runx2b (runx2b,runx2,LOC107678859,LOC107726745,LOC107697170,LOC107603075)


Basic Information

Item Value
gene id runx2b
gene name runx2b,runx2,LOC107678859,LOC107726745,LOC107697170,LOC107603075
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056718.1
NCBI id CM032087.1
chromosome length 27616869
location 22622388 ~ 22662318 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043218703.1
CCAGAAGAAGGAAAACAGAGGAAGGAAAAAAGCTGGCCCGCACGACTCCAGTGATGTCACGAGCATGTGACCCTGCTTCTCCAGTGACAGCGTTCtgagggaaagaaaaaagattttttaaaggCTCGTGCCTCTTTGGGTTTGTGTGAAGGCTCTGCTCACCTCCCGAGCAACCACAGAACCACAGAAAAGTTCGGCTCGGGATTTTTGCACGGCGGCGCTTCAATGGTTAACTGTCGCCGGTCAACTTCAGGTTTGAGGACCGCACCAACCAAGGCGTCAAGGGTCACCGAAAACCGCAGAGAAGCGAAATTTGGGCAACCATGGCATCCAACAGCCTCTTTAGTTCTGTGACCCCATGTCAGCAGAACTTCTTCTGGGATCCCAGCGCCGGCCGGAGGTTCAGTCCGCCGGTGTCGGTGAAGATGAACGATGTGAACCCGAGCGCaggacagcagcagcagcagcagcagcaggacgGCGCCGTGGTGCCAAGGCTCCGCGCGCAAGAGAACCGCTCCATGGCTGAGATCATCGCCGACCACCCCGCCGAACTGGTCCGGACCGACAGCCCGAACTTTCTCTGCTCGGTCTTGCCTTCTCACTGGAGGTGCAACAAAACTCTCCCGGTTGCGTTTAAGGTGGTGGCCCTGGGAGAGGTTCCTGACGGGACGGTGGTCACAGTAATGGCTGGGAATGATGAGAATTACTCAGCTGAGCTCAGGAATGCCTCAGGTGTTATGAAGAACCAGGTCGCCCGCTTCAACGACTTGCGCTTTGTGGGCCGAAGCGGAAGAGGGAAGAGCTTCACCCTGACGATTACAGTATTCACAAACCCACCGCAAGTGGCCACTTACCACAGAGCCATTAAGGTCACGGTGGACGGACCGCGGGAGCCCAGGAGGCACAGGCCGAAGTTGGATGACTCGCCAAAGGCTGGACTGTTCTCTGACCGTCTCAGTGAACTGGAGCGTATCCGGCAGACCACCATGCGGGTTACTGTGCCAACGCAAACGCCACGGCCGTCGCTTAGCAGCCCCAACTCCTTCACACCTCAGGGGCAGACTCAGATAACAGATCCACGCCAGGCTCAGTCTTCCCCACCTTGGTCATATGACCAGACGTACCCGTCGTACTTAAGTCCCATGGCCTCCCCGTCTGTGCACTCCACCACCCCGCTCTCTTCCAGCCGGGCCACTGGGCTGCCCTCCATCAGCGATGTGCCCAGACGCCTCCCAGGTTCGACAGATTTGAGTCCTTTTCCTGGCCAATTTGAGCGTCAGTTCCCCGCCTTCTCCTCGCTCACCGAGAGCCGTTTTTCCAGTCCCAGAATGCACTACCCGGCCACCTTCACGTACACGCCCACCCCCGTCAGCACCGGCATGTCCCTCGGCAGCGCTCACTACCACACCTACCTGCCCCCGCCGTACCCCGGCTCCACCCAGAGCCAAAGCGGACCCTTCCAGAGCAGCAGCACACCTTATCTCTACTACGGCGCCTCCTCGGGCTCCTACCAGTTCTCTATGGTTCCGGGCGGAGACCGGTCGCCCACCCGGATGATGCCGCCTTGTACTAGCGCATCTACGGGAACCAGCCTGGTCAACCCCAACCTCCCGGTCCAGGCCGATGGAGGCGGAGGGGTGGAGGGGGACGGAAGTCATAGCAACTCCCCCACTCTTCTCAATCCTGCTGGTAGAATGGACGAAGGCGTGTGGCGGCCATATTGATCGGACAATTACGTGAGCGTGGAACcttcaaacaaacagcatgGTTTTAAAGCACAAACCTTACTAGGATGTTCATCCTGTCTCGCTGAGCTACTTTCCCTCGCTAACATGAGTATTTATGAGCCTGTTGAAAGGGAAGTATTTTTTACATTGGACTTTTGTTGTTATTCTGGACCTTTTGACCTCTGGGATTCATTGTTATAGGCGGGATTATTTAGAATTGAAGGAATAGAGATGGATCGAGTATTTCATTAGCATTATGTCATTATATACTTGTCTtggcatgtttttaatatatcatttaaagcACTGAACAACATCTGTATGACCGTTTGTGATCGAATAtctctttttgtgcttttttttttaacttaagcaTTTAAGTTATACGTATTTGATAAAAGGATTTAAAGTAACTTATAAAAGCCATagattaaataatgtatttggaACTTGAGTCACAGAGGGAATATTTTTGTACAGCATCTATGTTCAAGTTAATGCAACTAATTTAGGGTAATTTAAATTTCTGTGCCTTAATTGATCACACAGAGTTGTATGTAGGGTCTCTGTGTCTAAGTACAATACATTTGTAAGCAGTTAATATTGCTTAATGATGCTAAGTGCTTTTTCACTGTTATAAAGCTTTAAACCAAAGAAACAGCCACGGATGCTCAAAAGTGTTTGCCAATGTGCTAGACCAAGCTTTCTTTGAGTAGCATGCATGTGCTGGGATAATTTATTTAGCTTATATGTTGCTTAACTAAACGCGGCTGGGAAAGGTTTCCAGTGGGGGAATATTGAAGGTTCTGGATGGTACAAGGATACTCTTTTCCTGATAACTGGAGCAATTCATATCCTCAAAAAAGAGGGTAATACACTCAGTTAAGGCACTATATTACCCATTGCAACAATGCAGCTGGagtaaattcctttttttttatttgtgttgtatttatagtatttaaacATTCGAAGTTTGGGgctcagtaattttttttaggaaattagTATTTTGCAAATgcgcattaaattgatcaaaaatcgACATGGATgagaaaacaattatatttcagATAAAGAGAAATgcatcagtttccacaaaaatacgaAATATATTTCAACgtgaattttaataataatacatattagaTCGATTTCTAAAGGCGCTATAGACTatggtaatgatgctgaaaattcagcttcgcgtcacagaaatgaaagaacattttaaaataaataaaagaaaaattgcagTGATGTTTTCACAGCGTTGCAGCTTTTATGCTAAagtgatcaaatgaatgcagcattaaaaaaactctatttttcaaaaacattaaacaaatcttactgagcccaaacttttgaccagtTGTGtagctatattttattttattgattattttattttattttattttatcgaCATTGTCGGTTATGAAACCTTAATTATCAGCTCAGTAATGTGCAAATTAGCTTCATGATTTCAGAATGCCAGTCGAGAAAAGACTGACTTGCCCAACTGCAATCGTCTAACGGAGTTATATTTATCGAGTGCCTTACGGTTGGAACTATACAGACCTCCCCAAACAACTGAAAGCTTTCTATGAAGCAGTGCTTTTTATACGGCTTATAAAGCCCATATttaagcaattaaattaaaataaaccaaagcTCTTAGCTTGAGTTGGATGTGTTTCTGACCTTCTTTACCTTAACATTGGTCCAGTATTGCATTTCTGGCAGAACTAGGTTCCTTTTGGCTGCTTCAAACCAGGGCCGTTGCTTGAATTCATCCCAGGATCCAGGTCGGCGTTCCCGGTTATCCCATCCTGACGGCAAAAACGGCTTCAAATCAGGGGCGTCTACCTATAAATTGAAATAGCTGTGAGTGTGTACGAAATGTTTACATCGTTCAGAGACCATGTCGTATATTACAGGAGGTAAATACACCACCCTAGTTTTGTTGAATTATTATCTCGTTTCTTCTTTTGTAAATTAGTATTTATCTGACAGGTTAACTGAGGGCAATTTGTAGCAAATTTGTCTCTGGTTCTTGCATGCTTTGTTTCCTTTGCACATCTGTGTTTAAATTATCTCGCTTTTCTTCCCTGTGAAGCCTGTTCTCTTTTATCCAAGGATAGAAAAAGGGTTTAAGGGAAATTATCATGACAACAGTGAAAGAAATTGGCTTTTTTTGATTGTTGTACGTTGTTATAATAGTTTTCTTTgtaagagaaataaaaaga
>XM_043218704.1
ATTGGGGCTTTATGAGTAAGCAGCTGAAAGAAGAGTAAGCTGCTCTCCTCGCATCACCTCAGGGTCAGAAGAGACAGGCTGCAGCACGCCGAGCGACCAACAGGGAAGGATGGAGAGGTAGAAAGAGAGCAGCAGGGAGAGAAGCACGAGCGTTCACGCCCCCCTCCGAAGCCTCATGACTCACGAGGGGTGAGCGGCAGCATCACGCCCACCCCTTCCCTCTCCAGTGCCAGGAAGAGCCGGCAAAACCACGCGTCTCCAGAAGAAGGAAAACAGAGGAAGGAAAAAAGCTGGCCCGCACGACTCCAGTGATGTCACGAGCATGTGACCCTGCTTCTCCAGTGACAGCGTTCtgagggaaagaaaaaagattttttaaaggCTCGTGCCTCTTTGGGTTTGTGTGAAGGCTCTGCTCACCTCCCGAGCAACCACAGAACCACAGAAAAGTTCGGCTCGGGATTTTTGCACGGCGGCGCTTCAATGGTTAACTGTCGCCGGTCAACTTCAGGTTTGAGGACCGCACCAACCAAGGCGTCAAGGGTCACCGAAAACCGCAGAGAAGCGAAATTTGGGCAACCATGGCATCCAACAGCCTCTTTAGTTCTGTGACCCCATGTCAGCAGAACTTCTTCTGGGATCCCAGCGCCGGCCGGAGGTTCAGTCCGCCGGTGTCGGTGAAGATGAACGATGTGAACCCGAGCGCaggacagcagcagcagcagcagcagcaggacgGCGCCGTGGTGCCAAGGCTCCGCGCGCAAGAGAACCGCTCCATGGCTGAGATCATCGCCGACCACCCCGCCGAACTGGTCCGGACCGACAGCCCGAACTTTCTCTGCTCGGTCTTGCCTTCTCACTGGAGGTGCAACAAAACTCTCCCGGTTGCGTTTAAGGTGGTGGCCCTGGGAGAGGTTCCTGACGGGACGGTGGTCACAGTAATGGCTGGGAATGATGAGAATTACTCAGCTGAGCTCAGGAATGCCTCAGGTGTTATGAAGAACCAGGTCGCCCGCTTCAACGACTTGCGCTTTGTGGGCCGAAGCGGAAGAGGGAAGAGCTTCACCCTGACGATTACAGTATTCACAAACCCACCGCAAGTGGCCACTTACCACAGAGCCATTAAGGTCACGGTGGACGGACCGCGGGAGCCCAGGAATCCACGCCAGGCTCAGTCTTCCCCACCTTGGTCATATGACCAGACGTACCCGTCGTACTTAAGTCCCATGGCCTCCCCGTCTGTGCACTCCACCACCCCGCTCTCTTCCAGCCGGGCCACTGGGCTGCCCTCCATCAGCGATGTGCCCAGACGCCTCCCAGGTTCGACAGATTTGAGTCCTTTTCCTGGCCAATTTGAGCGTCAGTTCCCCGCCTTCTCCTCGCTCACCGAGAGCCGTTTTTCCAGTCCCAGAATGCACTACCCGGCCACCTTCACGTACACGCCCACCCCCGTCAGCACCGGCATGTCCCTCGGCAGCGCTCACTACCACACCTACCTGCCCCCGCCGTACCCCGGCTCCACCCAGAGCCAAAGCGGACCCTTCCAGAGCAGCAGCACACCTTATCTCTACTACGGCGCCTCCTCGGGCTCCTACCAGTTCTCTATGGTTCCGGGCGGAGACCGGTCGCCCACCCGGATGATGCCGCCTTGTACTAGCGCATCTACGGGAACCAGCCTGGTCAACCCCAACCTCCCGGTCCAGGCCGATGGAGGCGGAGGGGTGGAGGGGGACGGAAGTCATAGCAACTCCCCCACTCTTCTCAATCCTGCTGGTAGAATGGACGAAGGCGTGTGGCGGCCATATTGATCGGACAATTACGTGAGCGTGGAACcttcaaacaaacagcatgGTTTTAAAGCACAAACCTTACTAGGATGTTCATCCTGTCTCGCTGAGCTACTTTCCCTCGCTAACATGAGTATTTATGAGCCTGTTGAAAGGGAAGTATTTTTTACATTGGACTTTTGTTGTTATTCTGGACCTTTTGACCTCTGGGATTCATTGTTATAGGCGGGATTATTTAGAATTGAAGGAATAGAGATGGATCGAGTATTTCATTAGCATTATGTCATTATATACTTGTCTtggcatgtttttaatatatcatttaaagcACTGAACAACATCTGTATGACCGTTTGTGATCGAATAtctctttttgtgcttttttttttaacttaagcaTTTAAGTTATACGTATTTGATAAAAGGATTTAAAGTAACTTATAAAAGCCATagattaaataatgtatttggaACTTGAGTCACAGAGGGAATATTTTTGTACAGCATCTATGTTCAAGTTAATGCAACTAATTTAGGGTAATTTAAATTTCTGTGCCTTAATTGATCACACAGAGTTGTATGTAGGGTCTCTGTGTCTAAGTACAATACATTTGTAAGCAGTTAATATTGCTTAATGATGCTAAGTGCTTTTTCACTGTTATAAAGCTTTAAACCAAAGAAACAGCCACGGATGCTCAAAAGTGTTTGCCAATGTGCTAGACCAAGCTTTCTTTGAGTAGCATGCATGTGCTGGGATAATTTATTTAGCTTATATGTTGCTTAACTAAACGCGGCTGGGAAAGGTTTCCAGTGGGGGAATATTGAAGGTTCTGGATGGTACAAGGATACTCTTTTCCTGATAACTGGAGCAATTCATATCCTCAAAAAAGAGGGTAATACACTCAGTTAAGGCACTATATTACCCATTGCAACAATGCAGCTGGagtaaattcctttttttttatttgtgttgtatttatagtatttaaacATTCGAAGTTTGGGgctcagtaattttttttaggaaattagTATTTTGCAAATgcgcattaaattgatcaaaaatcgACATGGATgagaaaacaattatatttcagATAAAGAGAAATgcatcagtttccacaaaaatacgaAATATATTTCAACgtgaattttaataataatacatattagaTCGATTTCTAAAGGCGCTATAGACTatggtaatgatgctgaaaattcagcttcgcgtcacagaaatgaaagaacattttaaaataaataaaagaaaaattgcagTGATGTTTTCACAGCGTTGCAGCTTTTATGCTAAagtgatcaaatgaatgcagcattaaaaaaactctatttttcaaaaacattaaacaaatcttactgagcccaaacttttgaccagtTGTGtagctatattttattttattgattattttattttattttattttatcgaCATTGTCGGTTATGAAACCTTAATTATCAGCTCAGTAATGTGCAAATTAGCTTCATGATTTCAGAATGCCAGTCGAGAAAAGACTGACTTGCCCAACTGCAATCGTCTAACGGAGTTATATTTATCGAGTGCCTTACGGTTGGAACTATACAGACCTCCCCAAACAACTGAAAGCTTTCTATGAAGCAGTGCTTTTTATACGGCTTATAAAGCCCATATttaagcaattaaattaaaataaaccaaagcTCTTAGCTTGAGTTGGATGTGTTTCTGACCTTCTTTACCTTAACATTGGTCCAGTATTGCATTTCTGGCAGAACTAGGTTCCTTTTGGCTGCTTCAAACCAGGGCCGTTGCTTGAATTCATCCCAGGATCCAGGTCGGCGTTCCCGGTTATCCCATCCTGACGGCAAAAACGGCTTCAAATCAGGGGCGTCTACCTATAAATTGAAATAGCTGTGAGTGTGTACGAAATGTTTACATCGTTCAGAGACCATGTCGTATATTACAGGAGGTAAATACACCACCCTAGTTTTGTTGAATTATTATCTCGTTTCTTCTTTTGTAAATTAGTATTTATCTGACAGGTTAACTGAGGGCAATTTGTAGCAAATTTGTCTCTGGTTCTTGCATGCTTTGTTTCCTTTGCACATCTGTGTTTAAATTATCTCGCTTTTCTTCCCTGTGAAGCCTGTTCTCTTTTATCCAAGGATAGAAAAAGGGTTTAAGGGAAATTATCATGACAACAGTGAAAGAAATTGGCTTTTTTTGATTGTTGTACGTTGTTATAATAGTTTTCTTTgtaagagaaataaaaaga

Function

symbol description
runx2b Enables DNA-binding transcription factor activity and vitamin D receptor binding activity. Acts upstream of or within chondrocyte differentiation; dorsal/ventral pattern formation; and positive regulation of transcription, DNA-templated. Predicted to be located in nucleus. Is expressed in several structures, including EVL; cranium; fin; osteoblast; and pharyngeal arch. Human ortholog(s) of this gene implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Orthologous to human RUNX2 (RUNX family transcription factor 2).
runx2 Enables sequence-specific double-stranded DNA binding activity. Involved in osteoblast differentiation; positive regulation of osteoblast differentiation; and regulation of transcription, DNA-templated. Located in nucleoplasm. Implicated in cleidocranial dysplasia and metaphyseal dysplasia-maxillary hypoplasia-brachydacty syndrome. Biomarker of esophagus squamous cell carcinoma.

NR:

description
PREDICTED: runt-related transcription factor 2 isoform X1

GO:

id name namespace
GO:0002062 chondrocyte differentiation biological_process
GO:0009953 dorsal/ventral pattern formation biological_process
GO:0045893 positive regulation of transcription, DNA-templated biological_process
GO:0005634 nucleus cellular_component
GO:0005524 ATP binding molecular_function
GO:0003677 DNA binding molecular_function
GO:0042809 vitamin D receptor binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K09280 RUNXA_B; runt-related transcription factor

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043218703.1 False 3979 mRNA 0.45 8 22622646 22662318
XM_043218704.1 True 4063 mRNA 0.45 7 22622388 22662318

Neighbor

gene id symbol gene type direction distance location
mmut mut,LOC107726757,LOC107697172,LOC107726528,LOC107667609 coding upstream 84527 22518165 ~ 22537861 (+)
mfsd2b si:dkeyp-115a10.3,mfsd2b,LOC107750078,LOC107697177,LOC107603080,LOC107667608 coding upstream 123780 22478061 ~ 22498608 (+)
LOC122325512 klhl29,LOC107667613,LOC107742703,LOC107697176 coding upstream 227954 22285647 ~ 22394434 (+)
trib2 trib2,LOC107742704,LOC107667617,LOC107717709,LOC107697179 coding upstream 463460 22150436 ~ 22158928 (+)
napbb si:rp71-81o21.2,napb,LOC107756672,LOC107667620,LOC107742707,LOC108411873,LOC107593246,LOC103023605,LOC106571745,LOC106610947,LOC100691502 coding upstream 530606 22085016 ~ 22091782 (+)
mark3b mark3b,LOC107697167,LOC107743287,LOC107678848,LOC108412004,LOC107726756 coding downstream 24254 22686572 ~ 22738127 (+)
laptm4a laptm4a,LOC107678852,LOC107726758,LOC107603102,LOC107743288 coding downstream 77315 22739633 ~ 22744277 (+)
ttc32 ttc32,LOC107678832,LOC107743292,LOC107697098 coding downstream 93674 22755992 ~ 22757979 (+)
zpax1 LOC107603073 coding downstream 96041 22758359 ~ 22763879 (+)
mixl1 LOC107743324,LOC107697096,LOC107726752,LOC107678837,LOC107603100,LOC107549665 coding downstream 105517 22767835 ~ 22769876 (+)
G141091 NA non-coding upstream 64886 22557229 ~ 22557502 (+)
G141084 NA non-coding upstream 79856 22542136 ~ 22542532 (+)
G141081 NA non-coding upstream 81061 22541118 ~ 22541327 (+)
LOC122324401 NA non-coding upstream 507521 22098405 ~ 22114867 (+)
G140933 NA non-coding upstream 520927 22101238 ~ 22101461 (+)
G141121 NA non-coding downstream 258375 22920693 ~ 22923128 (+)
G141168 LOC107603093,LOC107678851,LOC107549708,LOC107727631,LOC107697145 non-coding downstream 404269 23066587 ~ 23073665 (+)
LOC122324747 NA non-coding downstream 532303 23194621 ~ 23206082 (+)
G141207 NA non-coding downstream 667873 23330191 ~ 23332366 (+)
G141216 NA non-coding downstream 726174 23388492 ~ 23408824 (+)
fkbp1b fkbp1b other upstream 104705 22506727 ~ 22517683 (+)
ubxn2a LOC107742702,LOC107600119,LOC107603085,LOC107697178,LOC107750080,LOC107667622 other upstream 145614 22471761 ~ 22476774 (+)
G140785 NA other upstream 777687 21844146 ~ 21844701 (+)
ipo13b ipo13,LOC107745904,LOC107593276,LOC107697216,LOC107691006 other upstream 1420426 21168775 ~ 21201962 (+)
G140533 NA other upstream 1519878 21101768 ~ 21102510 (+)
matn3a matn3a other downstream 82094 22744412 ~ 22754161 (+)
si:ch211-203k16.3 LOC107549701,LOC107603096,LOC107697150,LOC108424433,LOC108257753 other downstream 180487 22842805 ~ 22860327 (+)
pln NA other downstream 681397 23343715 ~ 23351655 (+)
G141475 NA other downstream 1410553 24072871 ~ 24074423 (+)
G141524 NA other downstream 1777925 24440243 ~ 24493381 (+)

Expression


Co-expression Network