tsc1b (tsc1,tsc1b,LOC107595695,LOC107556942)


Basic Information

Item Value
gene id tsc1b
gene name tsc1,tsc1b,LOC107595695,LOC107556942
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056719.1
NCBI id CM032088.1
chromosome length 19199999
location 3617039 ~ 3634175 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043221479.1
TGCGTCCGGATACAGGCGTGTTTTTGAGCGCTCTGGGATTATTTCTCCTGCACAGCTGCGGAGGGTGACTGCGCAGGGAGGGTTGTGAGGTGTTCAAGATGGCGGCGCCCTGTGGAGTGCAGTTGCTCTAACAGTGGTGCCTGGAGACTGTATTGATGGGTGGCCCAGGGACCCCTCCAGGCTGGACAGGACACGGGACGGCGTGAGAGTGACATCTAAGAGTCCTTCCCCTGTCCCTAGACTGTTTTAGAGACACCCGCCTCCGAACCCTCCATACCACCATGTCCAGGGAACAGCTCAGCGTGGGGGACCTGCTTCCTCTGCTGGAGACCTCTGACCTCCGCCAGCTGGATGAGATCAAAGGCCTCATCAATGAACACCTCAACACAGATCGAGGGTCCATGCTGCTGAACGGCTTGGTGGACTATTTCCTGGAGACCAATTCCGCCCAGGCAGTGCACATCCTGTCCTCAGTGAGGGAGCCACATGATAAGCACCTTtttgataaaatgaatgaatgcatggcTAAAGCCCCCTGTCGCCTGCCCACACTCACTCTTCTGGGGCACGTTGTCCGTAAGCAGCCATCTTGGATCCACAAGATTGCTCGCTATCCGCTGCTGCTATCTCTCCTGAAATGCCTCAAGACAGACACCGATGTTGTGGTTCTTATAACTGGAGTCCTTGTGCTCATCACACTATTACCCATGATTCCCCAAGCTGGCAAGCAGCATCTCTATGAATTTTTTGATATCTTTGGCCGTCTGGCTTCTTGGAACCTGAGAAACCCAGGACACGTCCCAGAGGTTTATCTCATCCACCTGCATGCAAGCGTCTACTCTCTCTTCCACCGGCTGTATGGGATGTATCCCTGCAATTTTGTGTCTTACTTGCGCTCCCATTACAGCATGAAGGAAAACATGGATACTTTTGAGGAGGTGGTCAAGccCATGCTTGAACATGTGAGAATACATCCCGAATTAGTGACTGGAACCAAGGACCATGAACTAGACCCCAGTCGGTGGAAGAAATTTGAAATCCACGATATCGTTATTGAGTGTGCCAAAGTCTCTCTGGACCCAAAGGAGGCGTCCTGCGAAGAGGGCTATGCCAGCATGCCTGAGCATTTCTGTGCTCATCTACAACAACGTCCGGCTGATTGCACTGCCAGCCCTTACGGCGACTTCCACAGTAGCTACGGAAGTTCTTCCTCGACTCATTTCTCAACCCCTCGTCAGCCTGTCGTCCCTCCCTTGGCCCTGTCCTCTTTCTCAGGGACTCAGCCCCCCTATCGCAGTCCTACTGGAACCCGTCGACAGaacTCCAGCTGTGAATTTAATGCCACATATGGTTTTAAGGATTCCCTCTGGAGCCCCTCCTCTCAGTGTGGCATGGCCACACCTCCTTCCTCCCGTGGGATGTCACCGAATCCGGAAGTGTCCCAGAGTGCCTCTCACCTACCAACCCGCCTCTACAGCACACCTGGTGGTAAAGGCACCCCGTCCTCTAGCACCCCTGCGGCCGCCTCACCTCCTCCTAGCCTCTCTGATGAGTTTCTCCCTGTGTCTCTGCCTTGCAGTACCGCCAGTCCACCATGCAAGGATGGTAGACCTTTAGACCACACCAAACCCATCTTGGTCAGACAGGAGCCAGTCAGACAGGAGCTAGAAAGAGAGTTTGAGAAAACTGGACCTGAAACCATCAATCACAGAGATGAGAGAGGTGAGAACATGCCCATGACCCTGACCGAGCTGTCTGTGTACATGAAGGAGCAAGAACAACTGAGGATCGAGAAAGAGCGCGAGGACGCTGCCATTACAGAGGAGCTTCTGAAGTTAACAGAGGAAAAGCGGGATTTAGCTGGCCTTCGTGGCTTTGACTCTCCATTCTTCAGCACCACAGAGACCCTGACCGGAGCGCAAGAGAAACCCCTTCCTTCTTCTATCCTAGGCAGCTCAATTAGAGACCCTCACAACATGATCTCCACACCTGACAAGGCCGAGATCACGGCCAGCGACAGAGGCAGAGTCAGCAGAGGCCCATCCCAGGAGCATCCCTGGAACTTCCGGCCAGTGTTTATGCCCATCGAACACCCAACACACAGCCACCTCCATCGGAGCCCCTCCGCACCTGAGGACGAGGCccttaaatacagtttttgctCCCCGAGCCCAAGCAAGCCCCCACCCCTTGCCTACGAGGCTCTGTTTGACCTGGCCCTGCCTCGGGCAGCCTCTCTCTTCGTGGGGAGGAAAACCTCGGAGATTGTGCAGCGAGTAGCCTTGGAGAGGATCCAGAGAGGTGATGTGAGCAAGCAAGTGGAGGAGGGGTGTGTTGAGGGGGCTGTGTCTGCCTCACCTTTGGAGGTGCTAGATCGCCTCGTGCAGCAGGGCGGTGACGCCCATGACAAAGTGTTAAAAAGATTGCCTCTGCCAAGCAAGTCAGCTGACTGGACACACTTTGGAGGCTCTGCTCCTCTGGATGAGCTGCACACACTGCGCAGTCAGCTGCTTCTGTTACACAACCAGCTCTTATACGAGCGCTACAAGCGGGAGCAGCACGCCGTACGCAACCGACGTCTGCTTCGTCGAATCATCAATGCCACCGCGCTCGAGGAGCAGAATAACGCCATGaAGGACCAGCTGAACCTGCAGAGTGTGGATATCATGTCTTTGAGAGAGAGCCTGCAGGTAGAGCAGCAGAGATACCGGCAGCTCTGGGACGACCGAGAGACTGTAGTTACACGCCTGCACAGCCAGATACGCCAGCTACAACAGGCCAGAGATGACTACTACACCAAAAACCAGGAGTTACAGAGTAAACTACAGGAATGCCAGAAGCGAATAGGTGAGATGGAGGCGGAGCTGCAGAAGGCGAACAACAAAGTGTGCCACACAGGACACCTGCTAAATCAGCTTACTGCCAAGTTGTCATCGAGTGAAAGTATTCAGCAGCAGTTGAGTTTTCTAAACAAGCAGCTGCTGCTGCTAGGAGAAGCCCATAAACTGTGTGTTCAAGAGCTGCATCAGGCTGGACCAGATACTAGCAAGGAGGTCCAGATGCTGCAGACATCCTGGGGGAAGGAGACGGAGCGTCTAAAGCAGAATCTGTTACTTCAGAGCCAAAAGCTGGATGCTGCTCAGCAGAGAGTGGCAGAGCTAGAGACTCAACTCGCTAAGAAAGAGCACCTAATTGCAGAGCAAAAAAAGTTTCTAGAAGATGTCAAGGCTCAGGCTAAAGGGGAACTGCAGGCCTCCGAGAGCAGATATCAGGCACAGAGGCGAGTGACTCTGGCTCTGCAGACTGAGCTTCTGCAACTCTACAGCAGGCTGGAAACAGAGGACTCCTCTGGCACTGCTTCAGCCTTACCAGCAGAGAGCGCCACTGAACCCCGCAGTTCCCCCGAGCCCagTGTCATAGTGGTTGATGGTGCAGTAAAAACAGCCACCAAAGAAGACGGCAAGTCACCTCAGTCTCCACATGGCAATGGCAGCACCTTATCGCCAGCACAGCCAAGGCCAAGCAAGGCCAGCTCCTCCCCGGCCAACTCTGTAAACGGCAATCGAGACACTCCACCACCTGTCCTAGTGGAACCGCCCCCTCACCGTCCTCATTCCCCGCTGGGACCCCCAGGACCTTTGGTCCCGTCTGACACCCCACTCACTGTAGGCTCCTACCCCAGCGCCAAGAGCTTTCTGGGTATGCGTGCAAGAGAGCTATTTCGCAACAAAAGCGAGAGCCAGTGCGATGAGGATGAAGCCCCGCCCCCCCGTCTCACTGGCCTATCACAGGGTCTGAAAACTGAGCTCTGCGTGGAGCCGACAGCGAAGAGTACATCCAGCTCCACCACTGCGCAGAGCTTCACGCTCATCACATCCGCAAAAGAAACCCAACCTGATGCTCAGAGAGCCAAAAACCGAGACACGTTCGGGTCAAGATGCCCAGAGAGGCCCAGGCAGCAACCGTTAAGGATCATGGACTATAACAAAAGTCATCAGGAGCACAGCTAAAGTTATggaaaaatggagaaaaagagtGGTAGAGGGTCGAGAGATTGCAAATTTAGAATATTAGAGCGCAAGGCAAGACTCTTTCAATTTTCAGTGTTATCTGTCCCATTTCCACAAGCCGACAACAGGATTTGGAGTTAATAAATCAGTAAAACCCTCACTAAGATGGGACGAGTAAAAAGAATAGACTAAACCAACATATAAGTGGTCACAAAATGTCTTCTAGCAACCCCACTGCGTTGTTCACCAGAAATGTCACCGCTGcatctttttatttgttgttttttgctcatttatctGCTCCCTTTAACCAAGTTGTTGCAGCTCGTGGAAACTTTGCATTTATGTTGTTAGAAGCAATATAAGTTGATTTGATTTGTAGTGATGGTACAATGCTTACACCCTCACAGCTCACCCGCACAGAGCTGAAGTGTGTGCTTGGATGCCAGGAGGTGGATGGTTGTCTTGTGCCAAGCAGAAGtcagtgtttctttttaaaaccatCAGGTTTTACCTTTCAGACATGTCAGGTGCATTTATATGTGCTCAAATCATGTTTCTGTActatttttctgtgtgtgtgtgtgtgtgtgtgtgtgtatgtgtgagagagaaagtgatgGCCTGTATCCCAGACTTTTTTCTGGGTTAAATTGCACTGTAAGTTGTTACTGATTACGGAAAAAAATCTGTTACAGTCTTGGACTAGACTAAATCTGGATCCGAGAGATGATGCAGCCACAACGAGAGGAAGGTTcaacgtgttttttttaatatatttttttaattatttattttttcgtcctcttcttctttttagattttcaagTATTACCAGTTCTTTTAAAAGCTGTAAAGCAACGTAAACGAACAGCGGCCATAGATTCCTGACCATTACCCACGAGTCAAACCTATGAATCCTATCCTTCAGTAATCTCTATAAAACATCTAGTTACTATTTTCGAAGCCTTATCTTAATAATAAGTCAGACATCAGTCAAGTAATTTGCTTTAACGATACTAACCTTCAGTCTCAAGCTCAGTCATATTTTGCTGAAAACACGGTAGGACACGGTGATCTGTATTTTACCCTCTGCTTTCTCAGTGCCAAATACCCGATACAGTATTCTGTAGAGCTTAAATGTACTGGTTTTGTTCTAATATTCAAGCACATATATACTTAAGACTACCACATATCAGCTTGAGGGAGCAAATAAGACTTGATTTTGATGAGCTGAAAGCAATGAGATCTGTGCAATGCCAAGTAGACAGTGTAAAATATCAATTTTCTTTGACAAAATGGCCATAATAATAGGCTACGTTTAGGAATTGTGGATGGGGTGGTCATACACAAATCGTTCCCAAATCCTGTTGTCCTCTTGAAGTCTCTGCTGTTCCTTCTGCCTTGCTATCTAGAGCATGTACAACAATCCTCTTTTAATGCCAACAACAGGAACTATGACTTAACAAGATACAAGGTACAATCAGTGTGAAATGAAAGGAAGGTATGAATTCGAGCTCCTTTGCTGAAGATGAAAGTTCTGGGGTTTGTTGGGGGAGGAAAGGCAGGGTCGGTTGGAAAAGGTTCTTAAAGCAGTTGCTTGTGTTAACtgtgaatgacaaaaataaaatcgtCTTCAATGTTTTGCACTACA

Function

symbol description
tsc1b Predicted to be involved in negative regulation of TOR signaling; negative regulation of cell population proliferation; and regulation of cell cycle. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of TSC1-TSC2 complex. Human ortholog(s) of this gene implicated in intellectual disability; lymphangioleiomyomatosis; tuberous sclerosis; and tuberous sclerosis 1. Orthologous to human TSC1 (TSC complex subunit 1).
tsc1 Enables several functions, including chaperone binding activity; heat shock protein binding activity; and protein N-terminus binding activity. Involved in several processes, including activation of GTPase activity; negative regulation of ATPase activity; and regulation of cellular protein metabolic process. Located in several cellular components, including cell cortex; lamellipodium; and lipid droplet. Part of TSC1-TSC2 complex and chaperone complex. Colocalizes with actin filament. Implicated in intellectual disability; lymphangioleiomyomatosis; tuberous sclerosis; and tuberous sclerosis 1. Biomarker of breast cancer and pleomorphic xanthoastrocytoma.

NR:

description
unnamed protein product

GO: NA

KEGG:

id description
K07206 TSC1; tuberous sclerosis 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043221479.1 True 5664 mRNA 0.50 22 3617039 3634175

Neighbor

gene id symbol gene type direction distance location
trnam-cau_115 NA coding upstream 1808 3615160 ~ 3615231 (+)
bcr bcr,LOC107595694,LOC107679847,LOC107556943,LOC105889081,LOC105014833,LOC106566295 coding upstream 14559 3544243 ~ 3602480 (+)
atp2a2b atp2a2b,atp2a2,LOC107708347,LOC107556944,LOC108444117 coding upstream 74301 3514033 ~ 3542738 (+)
arpc3 arpc3,LOC107737855,LOC107707141 coding upstream 111452 3503222 ~ 3505587 (+)
gpn3 gpn3,LOC107686892,LOC107692302,LOC106563155 coding upstream 114297 3499645 ~ 3502742 (+)
stom stom,LOC107741953,LOC107556938,LOC107708355 coding downstream 103206 3737381 ~ 3748407 (+)
rxraa rxraa,rxra,LOC107708356,LOC107679846,LOC107556936,LOC107686886,LOC107573462 coding downstream 152584 3786759 ~ 3918707 (+)
brd3a LOC107708359,LOC107686882,LOC107573464,LOC107741956 coding downstream 303203 3937378 ~ 3945807 (+)
vav2 vav2,LOC107661185,LOC107722824,LOC107684912 coding downstream 312891 3947066 ~ 4074419 (+)
stx2a LOC107708345,LOC107565383,LOC107661188,LOC107566207,LOC107722811,LOC107684913 coding downstream 468731 4102906 ~ 4106152 (+)
G143638 NA non-coding upstream 6989 3608919 ~ 3610050 (+)
G143590 NA non-coding upstream 124452 3488511 ~ 3492587 (+)
LOC122326852 NA non-coding upstream 280350 3336261 ~ 3336689 (+)
G143578 NA non-coding upstream 301566 3315177 ~ 3315473 (+)
G143509 NA non-coding upstream 679422 2930262 ~ 2937617 (+)
G143656 NA non-coding downstream 117424 3751599 ~ 3752198 (+)
LOC122326834 NA non-coding downstream 129157 3763332 ~ 3769556 (+)
G143664 NA non-coding downstream 169283 3803458 ~ 3803769 (+)
LOC122326258 NA non-coding downstream 285558 3919733 ~ 3921719 (+)
G143717 NA non-coding downstream 441352 4075527 ~ 4086526 (+)
LOC122326950 ehmt2,LOC107661424,LOC107739706,LOC107706570,LOC107566632,LOC107751678,LOC107694038,LOC107694747,LOC107557450 other upstream 297026 3297990 ~ 3320013 (+)
gnrh2 LOC107595723 other upstream 786683 2829114 ~ 2830356 (+)
G143321 LOC107739705,LOC107661415,LOC107736881,LOC107692311,LOC107548771 other upstream 1379844 2233659 ~ 2237195 (+)
stxbp1a stxbp1a,stxbp1,LOC107661518,LOC107736879,LOC108437460 other upstream 1560360 2030104 ~ 2056679 (+)
LOC122326311 NA other upstream 2387984 1227998 ~ 1229055 (+)
G143650 barhl1b,barhl1,LOC107556939,LOC100712077,LOC102792687,LOC107708351,LOC107595696 other downstream 67254 3701429 ~ 3704397 (+)
G143725 si:ch73-287m6.1,LOC107565381,LOC107708362 other downstream 472626 4106801 ~ 4213772 (+)
G143726 si:dkey-112m2.1,LOC107661187,LOC107708339,LOC107565378,LOC107684910,LOC107566201,LOC108437247 other downstream 498261 4132436 ~ 4386212 (+)
si:ch211-222n4.2 LOC107722820,LOC107591717,LOC107685267,LOC107589267,LOC107706417 other downstream 877751 4511926 ~ 4524180 (+)
btc LOC107706483,LOC107681194,LOC107722828,LOC107703511 other downstream 1070982 4705157 ~ 4709441 (+)

Expression


Co-expression Network