nkx6.1 (nkx6-1,nkx6.1,LOC107706438,LOC107700773,LOC107722812,LOC107703597,LOC107591753)



Basic Information


Item Value
gene id nkx6.1
gene name nkx6-1,nkx6.1,LOC107706438,LOC107700773,LOC107722812,LOC107703597,LOC107591753
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056719.1
NCBI id CM032088.1
chromosome length 19199999
location 4585890 ~ 4588458 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043221810.1
TCAAGCTTCATCGTTCAGTGATTGTTCCGCGATTTATCTGCGGAGTGTTTAAGCCCTGTCCACAGAGACTTTTAAGCTCGTAAGATATCCCACTGCCTCACATGACCGGCACGCATGCAGATGTCCCTTTATTTAAGAAATAGATCTCAAATTGACTAGATTGATTTTGTCtcctttttgtatttaatagcTGGTCGGATGGCAGCTCTTTTAATGTGCAAATGAGAACCAATGAGGACAGACTCCTAAATTCAGTTCAGACACTCATCTGACACGGGCCACGTCACCGCCGGCCTCAGCCAATCGCGTCGCGCCGAGCCCCTCCACTTTCCCAGGCACGCTCTCAAAGTTTTGACTTTTTGCAGCAAAAGACGGCAGgttgatgaaaatgttttattatcttcCAGATCTTCATGTGAACTACCCAGAAAgactctctttttatttatagatttcaAAAACGCTCTCGTTGAAAGGACGCCGCTCTGTCGTATCATGCAAGAACTGAAAGAAGGGAATGGATTTTGCCAGAGGAGATGGGTATGAAGCTTCGGTGCAACTGATTGGGATTTTTTAGagaaaataacctttttttctaaaggcttgagtgtttttgtttggtttttccccctccttcctctctctctctctcttattcacTGTTTCGCGTTTGTTTTTACGTTTGGCGCTGGTCTCCATCGTCTTGCTTCTTGCGCAATATTTAGTTGAAGTTGAAGTTTCTTGGTAATGTTAGCTGTGGGGCAAATGGACGGGTCTCGCCAGAGCGCTTTCCTACTCAATACCCCACCTCTGGCTGCTTTACACAGCATGACCGAAATGAAGACACCACTTTACCCAGCATACCCGTTATCTTCCACCGGACCAGCATCCTCCACTTCGCCGACAGCTACCTCTCCGAATCCAGGCGGTATCCCGGTCTCGTCCCCGGGGATCAAAACATCCACCGGACTCTCGGTCCTCGGATCGCCCCAGTGCTCGATCGCCACACCTCACGGAATAAACGACATCCTCAGTCGACCCGCGGTGGTCACCGGAGCGGCGGCGGCGTCTTCTCCCGCTGGAATCTTGTCAGGACTGCCCCGCTTCAGCAGCCTGAGTCCTCCGCCGCCTCCAGGGCTGTATTTCAGCCCCAGCGCCGCGGCCGTGGCGGTGGCTCGTTATCCGAAACCCCTGACGGACCTTCCAGGCAGAACCCCTATATTCTGGCCTGGAGTTATGCAAAGCCCGCACTGGAGAGACGCCAGATTTGCTTGTTCCCCACATCAAAACTCGGTGCTCCTGGACAAGGATGGGAAAAGGAAACACACGCGACCAACGTTTTCCGGGCAGCAAATTTTTGCCCTGGAAAAAACATTTGAGCAAACGAAATATTTAGCTGGACCCGAGAGAGCGCGGCTGGCCTACTCTTTAGGAATGACAGAGAGCCAGGTCAAGGTGTGGTTTCAAAACCGAAGAACAAAATGGAGAAAACGGCACGCGGCCGAAATGGCCTCGGCGAAGAAGAAACAAGATTCGGAGACCGAGAGGCTGAAAGGGGCTTCGGAAAACgaagacgacgacgacgacTACAACAAACCCCTGGACCCAAACTCGGACGATGAGAAAATAACGCAGctgctgaaaaaacacaaaccgaACTCGGCTCTTATCATTCACACGTCGGAAAACGAGAGCTCGTAAAACGGAAACGGCGAACGGTCCGTCCGGTTCTTCGAGAAGTGTCAAAATATAATGTAGGCTGCTG
>XM_043221811.1
TCAAGCTTCATCGTTCAGTGATTGTTCCGCGATTTATCTGCGGAGTGTTTAAGCCCTGTCCACAGAGACTTTTAAGCTCGTAAGATATCCCACTGCCTCACATGACCGGCACGCATGCAGATGTCCCTTTATTTAAGAAATAGATCTCAAATTGACTAGATTGATTTTGTCtcctttttgtatttaatagcTGGTCGGATGGCAGCTCTTTTAATGTGCAAATGAGAACCAATGAGGACAGACTCCTAAATTCAGTTCAGACACTCATCTGACACGGGCCACGTCACCGCCGGCCTCAGCCAATCGCGTCGCGCCGAGCCCCTCCACTTTCCCAGGCACGCTCTCAAAGTTTTGACTTTTTGCAGCAAAAGACGGCAGgttgatgaaaatgttttattatcttcCAGATCTTCATGTGAACTACCCAGAAAgactctctttttatttatagatttcaAAAACGCTCTCGTTGAAAGGACGCCGCTCTGTCGTATCATGCAAGAACTGAAAGAAGGGAATGGATTTTGCCAGAGGAGATGGCATGACCGAAATGAAGACACCACTTTACCCAGCATACCCGTTATCTTCCACCGGACCAGCATCCTCCACTTCGCCGACAGCTACCTCTCCGAATCCAGGCGGTATCCCGGTCTCGTCCCCGGGGATCAAAACATCCACCGGACTCTCGGTCCTCGGATCGCCCCAGTGCTCGATCGCCACACCTCACGGAATAAACGACATCCTCAGTCGACCCGCGGTGGTCACCGGAGCGGCGGCGGCGTCTTCTCCCGCTGGAATCTTGTCAGGACTGCCCCGCTTCAGCAGCCTGAGTCCTCCGCCGCCTCCAGGGCTGTATTTCAGCCCCAGCGCCGCGGCCGTGGCGGTGGCTCGTTATCCGAAACCCCTGACGGACCTTCCAGGCAGAACCCCTATATTCTGGCCTGGAGTTATGCAAAGCCCGCACTGGAGAGACGCCAGATTTGCTTGTTCCCCACATCAAAACTCGGTGCTCCTGGACAAGGATGGGAAAAGGAAACACACGCGACCAACGTTTTCCGGGCAGCAAATTTTTGCCCTGGAAAAAACATTTGAGCAAACGAAATATTTAGCTGGACCCGAGAGAGCGCGGCTGGCCTACTCTTTAGGAATGACAGAGAGCCAGGTCAAGGTGTGGTTTCAAAACCGAAGAACAAAATGGAGAAAACGGCACGCGGCCGAAATGGCCTCGGCGAAGAAGAAACAAGATTCGGAGACCGAGAGGCTGAAAGGGGCTTCGGAAAACgaagacgacgacgacgacTACAACAAACCCCTGGACCCAAACTCGGACGATGAGAAAATAACGCAGctgctgaaaaaacacaaaccgaACTCGGCTCTTATCATTCACACGTCGGAAAACGAGAGCTCGTAAAACGGAAACGGCGAACGGTCCGTCCGGTTCTTCGAGAAGTGTCAAAATATAATGTAGGCTGCTG

Function


symbol description
nkx6.1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within cell fate commitment; enteroendocrine cell differentiation; and spinal cord motor neuron differentiation. Predicted to be active in nucleus. Is expressed in several structures, including DEL; endoderm; nervous system; neural tube; and pancreatic system. Orthologous to human NKX6-1 (NK6 homeobox 1).
nkx6-1 Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in several processes, including detection of glucose; positive regulation of type B pancreatic cell development; and regulation of transcription, DNA-templated. Predicted to act upstream of or within several processes, including neurogenesis; regulation of axon extension; and regulation of neuron migration. Located in extracellular exosome.

NR:

description
PREDICTED: homeobox protein Nkx-6.1

GO:

id name namespace
GO:0021522 spinal cord motor neuron differentiation biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0045165 cell fate commitment biological_process
GO:0003309 type B pancreatic cell differentiation biological_process
GO:0003310 pancreatic A cell differentiation biological_process
GO:0005634 nucleus cellular_component
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0000976 transcription regulatory region sequence-specific DNA binding molecular_function

KEGG:

id description
K08030 NKX6-1; homeobox protein Nkx-6.1

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043221810.1 True 1765 mRNA 0.50 3 4585890 4588458
XM_043221811.1 False 1478 mRNA 0.52 4 4585890 4588458

Neighbor


gene id symbol gene type direction distance location
rpl17 rpl17,LOC107722835,LOC107700774,LOC107703598 coding upstream 2588 4580634 ~ 4583302 (+)
LOC122327011 NA coding upstream 2733 4583099 ~ 4583157 (+)
LOC122327008 NA coding upstream 3900 4581918 ~ 4581990 (+)
LOC122327010 NA coding upstream 4764 4581051 ~ 4581126 (+)
nefla LOC107700775,LOC107706475,LOC107589231,LOC107703600,LOC107591713,LOC107722831 coding upstream 28264 4554358 ~ 4557626 (+)
abraxas1 fam175a,LOC107681177,LOC107589234,LOC107703595,LOC107591751,LOC107722832 coding downstream 98458 4686916 ~ 4690339 (+)
helq helq,LOC107681193,LOC107591711 coding downstream 103734 4692192 ~ 4698582 (+)
hpse hpse coding downstream 110268 4698726 ~ 4704776 (+)
amacr amacr coding downstream 132298 4720756 ~ 4729360 (+)
LOC122326163 LOC107681122,LOC107589283,LOC107706442 coding downstream 166168 4754626 ~ 4757400 (+)
LOC122326582 NA non-coding upstream 7762 4563334 ~ 4578128 (+)
G143745 NA non-coding upstream 33422 4551421 ~ 4552468 (+)
G143717 NA non-coding upstream 499364 4075527 ~ 4086526 (+)
LOC122326258 NA non-coding upstream 664171 3919733 ~ 3921719 (+)
G143664 NA non-coding upstream 782121 3803458 ~ 3803769 (+)
G143751 NA non-coding downstream 268 4588726 ~ 4589152 (+)
G143826 NA non-coding downstream 162759 4751217 ~ 4751510 (+)
G143827 NA non-coding downstream 163449 4751907 ~ 4752259 (+)
G143872 NA non-coding downstream 211644 4800102 ~ 4862403 (+)
G143887 NA non-coding downstream 302680 4891138 ~ 4893087 (+)
si:ch211-222n4.2 LOC107722820,LOC107591717,LOC107685267,LOC107589267,LOC107706417 other upstream 61710 4511926 ~ 4524180 (+)
G143726 si:dkey-112m2.1,LOC107661187,LOC107708339,LOC107565378,LOC107684910,LOC107566201,LOC108437247 other upstream 199678 4132436 ~ 4386212 (+)
G143725 si:ch73-287m6.1,LOC107565381,LOC107708362 other upstream 372118 4106801 ~ 4213772 (+)
G143650 barhl1b,barhl1,LOC107556939,LOC100712077,LOC102792687,LOC107708351,LOC107595696 other upstream 881493 3701429 ~ 3704397 (+)
LOC122326950 ehmt2,LOC107661424,LOC107739706,LOC107706570,LOC107566632,LOC107751678,LOC107694038,LOC107694747,LOC107557450 other upstream 1265877 3297990 ~ 3320013 (+)
btc LOC107706483,LOC107681194,LOC107722828,LOC107703511 other downstream 116699 4705157 ~ 4709441 (+)
slc45a2 slc45a2,LOC107589269,LOC107681104,LOC107591731 other downstream 142145 4730603 ~ 4745266 (+)
fybb LOC107706487,LOC107681167,LOC107589243 other downstream 311032 4899490 ~ 4911816 (+)
tnksa tnksa,tnks,LOC107706493,LOC107681059,LOC107591704,LOC108279024,LOC108436993 other downstream 359126 4947584 ~ 5028046 (+)
qpctlb qpctl,qpctlb,LOC107706454,LOC107703555,LOC107708501,LOC107591735 other downstream 912645 5501103 ~ 5506433 (+)

Expression



Co-expression Network