XLOC_006806 (sos2)



Basic Information


Item Value
gene id XLOC_006806
gene name sos2
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information


Item Value
chromosome id NC_007124.7
NCBI id CM002897.2
chromosome length 52186027
location 36638955 ~ 36663358 (-)
genome version GRCz11_2017_zebrafish_Genome

Sequence


>TCONS_00013102
tgcgcgccgtgtGAGCGGCTAAAGTTGTGTGGTTGTTCCCGGTGCTGGGAGCGCGCGGGGCCGATGCAGAGCAGGCATGCAGCACGACTTCAGCTCCAGCGAGGAGAACAGCGCGAGATGGCGAGGCCTGTTCGTGCAGGGGCTGCGAAAGGTGCAGGTGCAAGTGCATCCAAACCTGTCGGCTAAAGAAGATGCACTCCAGCACATTGAGGCACTTATACTGCAGCTCCTGAACAAGCTGTGTGTTACACAGCCCAGAACAATAGCTGATGTAGAGGACCGCGTCCAGAAGACGTTCCCAAATCCCATCGATAAATGGGCCATGGGTGACGCTCAGAATGCAATAGAGAAACGCAAGCGAAGAAACCCGCTGCTGCTGCCAGTTGATAAGATACATCCACTACTGAAGGAGGTGCTGGGCTATAAGATCGACTATAATGTGTGTCTATATATTGTTGCTGTGCTGGAGTACATCTCAGCTGACATCCTCAAGCTGGCTGGAAACTACGTGAGCAACATTCGACATTATGAGATCAGCCAGCAGGACATCACTGTCTCCATGTGTGCTGATAAGGTGTTAATGGATATGTTCGATCAAGAAGAGGAGATGGGGCTGTTGTCTCAGAGTGTGGAGGAGGTGTCTTCATCTGGTGTGCTCACATATGATGACCTGGTGCGTCTGGAGATCGCGGAGGAGCGTCAGTATCTGCGGGAGCTCGATCTCATCATCAAAGTATTCCGCCAAGCCTTTATGTCCAATAGCAAACTCTTCTCCGCTCAGGATGTGGAGCTGGCGTTCAGTAATATTCTAGAGGTTCAGGAGTTAACAGTGAAACTGTTGGGTCTTATTGAGGATGCGGTAGAAATGACAGCTGACGGGAGTCCACACCCTCTTGTGGGCAGCTGCTTTGAAGACCTCGCTGAAGAGCAGGCATTTGATCCCTATGAGACGCTCTCTCAGGACATCCTCTCTAAAGAATTCTGTCAACATTTCAACACACTGATGTCCCGCCCCACTGTAGCTCTGCACTTCCAGTCAATTGCAGAAGGCTTTAAGGAGGCAGTGCAGTACGTGCTTCCTCAGTTGATGATGGTTCCAGTTTACCACTGCATTCACTATTTTGAACTGTTACAGCAATTGCAGGAGTGCAGTGAAGAGCAAGATGACAGAGAGTGTTTGAAACAGGCACAGACTGCACTGATCAACCTACAATGCAGCATTGAACGCATATATGCTAAGCACCAACCACGGCGCAAACAAGGGGAACCACTGTATCGATTGTATAGTCGTGCATCTCGTAGCAAGCAGGCGGCTATAAAGCGTATGAACGACATCCAGAAGAGTATTGATGGCTGGGAGGGCAAAGACATTGGTCAGTGTTGTAGCCAGTTCATCCTGGAGGGGGCACTCCTTCGGGCTGGTGCCAAACATGAGCGGCACAACTTTCTATTCGATGGCCTCATGATAAGCTGCAAAGCCAATCAGAGCTCCAGGTTGCCAGGAGCAGGCAGTGGGGCAGAGTTTCGTCTGAAAGAGAAGTTCGTGTTACGCAAATATCGCATTGTAGATCGCGAGGATTCACCAGAGTTCCGTCATGCATTTGAGCTGGTGGGCCGTGAGGAAAGCGGAGCAGTGTTTAGTGCCCGTTCAGCAGAAGAAAAGAGTGCATGGATGGCTGCGCTGGTCACTCTGCAGTACCGGCCCACACTGGACCGCATGCTGGACACTGTCCTGCACCGTGAAGAACAAGCACAACCACTGAGGCTGCCATCACCAGACGTCTACCGGTTCGCCATCCAGGACTCCGAAGAGAATATCGTGTTCGAGGAAGGAGCACAAAGCAAGACTGGAATCCCCATTATTAAAGCTGGGACAGTGGTCAAGCTCATTGAGAGACTGACGTACCACATGTACGCAGACCCAAATTTTGTGCGTACGTTTCTGACTACATACCGCTCTTTCTGCAAACCACAAGACCTGCTCACACTACTGATTGAAAGGATTGAGATTCCAGAGCCCGAACCATCAGAAGCAGATCGAGAAGCTCTCTGGAATGGAGAACAACCAATGGCAGCTGAGCTTCAGAGATTTCGCAGAGAATACGTGCAGCCCGTCCAACTCAGGGTCTTGAATGTGTTCCGTCAGTGGGTGGAACATCACTTTTATGACTTTGAGAATGATCCTGAACTCTACGAGAGACTTGAAGGATATCTTATCAGCACCACACAGCTTAGAGGTAAATCTATGCGTAAGTGGGTGGAGTCTATCAGTAAGATCATGAGACGGAAGATACAAATGCAGTCTAACGGCATTAGTCACAACATTACCTTTGAGAGCCCACCTCCACCCATCGAATGGCACATCAGTCGCCCTGGGCAGGTCGACACCTTTGACCTCATGACCCTTCATCCGATAGAAATTGCTCGCCAGTTAACACTTCTGGAGTCTGATCTGTACAGAGCTGTTCGTCCGTCTGAGCTCGTAGGAAGTGTTTGGACAAAGGAAGATAAAGAGAAGAACTCTCCCAATCTGCTGAGGATGATCAGACACACAACCAATCTCACACTGTGGTTTGAAAAGTGTATAGTAGAGGCTGAAAATGTAGACGAGAGGGTTGCTGTATTTTCTCGCATTATTGAGATCCTGCAGGTGTTTCAAGAGCTTAATAACTTTAATGGGGTTTTGGAGATTGTGAGCGCCATCAATTCTGTACCGGTGTATCGTCTGGACCACACATTTGAGGCAGTGCCTGAGAGGAAGAGGAGGATTCTAGAAGAAGCTGTTGAACTCAGTCAGGATCATTTTAAGAAATATCTCGCCAAACTCAAGTCCATCAACCCACCCTGTGTACCTTTCTTTGGTATCTACCTGACTAACATTCTGAAGACTGAAGAGGGGAATCCAGATTTCCTAAAGCGGGACGGAAAAGAACTGATCAACTTCAGCAAGAGACGCAAAGTAGCAGAAATCACTGGAGAAATCCAGCAGTACCAGAACCAACCCTACTGCCTCAAAGTGGAACACGACATAAAGAGGTTTTTTGAGAATCTGAATCCAATGGGGAATATGAATGAAAAGGATTTCTCTGACTATTTGTTCAATAAGTCTTTAGAAATCGAACCACGGAACAGCAAGCAGCCACCTAGATTTCCCAGAAAGACTACATATTCTCTGAAGTCTCCGGGCGTTCGGCCTGTGCGCCAGGCGGTAGGTGGAGGAGGGACGCTAAAAGGTCACCCAGTGCCATTAGAAAGAGAACCACCTCACAAAATCACCTTCAGGAGCATCGCAGAAACTGAACCCGAGACGCCTCCCTCTCTGCCCACCTCTCCAAACACACCCACCCCTCCGCAGTCCGCCAGCTCTGACTTCAACTCTGTGTTTGAGCAGGACTTCATGCCCTACGGTAACAACACCATATTTGCCCCAGTTTTTCTGCCGCAGTCCAAGTTCCAGTCTGTGTCATGTGGTAGTTTACACCAGTTGATGAGTGATGAGCCACTCAAGCCCCCTCCATTACCTCCTCGCAGGAAAGATACTTCTTCAGATAAGAATTCCAGGTCTGACAGTCCTCCTGCCATTCCACCACGATTGCCTCCTCCTCCCCGCCTGCAGCCGCGTGTCCCAGTGATCAACGGGCCGACGGATGGGCCCTTGCCGAGCCCCCCACCACCTCTGCCCCGTGACCCCCTTCCGGACACTCCTCCACCAGTGCCCCAGAGACCACCCGAGATCTTCATCAACTACCCAGTGAACATGCAGCCATCTCCAGGGGGCCGTTTCCACTGGGACTTCACCACCTCACCTAGCACTCCTAATACCCCGCCTGGCACCCCCTCTCCCCGTGCTGTCCTCCCTGGAACCCCTTCTCCACGTGTGCCCCGGCGCCCCTGCACACCCAGCGTCAGTCAACCCATACTGGTTCACCTTCCTCCCCCGACACCGGCACCTCCCATCCCGCCTCGGCACAACTCCACCTCCGCCCTGCCAAAACTGCCACCCAAGACTTACAAAAGAGAACTGTCTCAATCTTCACACACTCTTTCTCAGCCCTCCCTACACACACTCTCGCTAGTTGACAACAGGGACAGCAACGAATAAGGGGGTGACCCTAAAATAGAGACGTTTGAGTTTTAACAACGTTTAACCTGGAAGCAGACAATCTGATGCTAGTAAAAACCTGAAGACGGTCATTGCTCTCGAAGAATGTGATTATCACTCATTTTTCACTTCCGTCACGTTCAGCATGCAAGGTCATGTGCTCGTCGACGGCACATTCGCTGATGGATTTACTGTTCCGAGGCCTTTCACCACCGTCAGACTCGGCTGTGGATGTTTATTTGGTTGCAGGTCAAAGGTTCATCCCTGGTTCAACCCGAACGCTCTCAGCACGCCTCTGTTCAGTTGCCTTTAACTCACAGCCGTGACCTTGACCAGAGATTGTACCCTTCAGGTGAACTCTGAACTCTTTGGTGAGAACTTTTTTCCTCACACTATTTAAAGCCAATATGATGTCTTAACCCCTCCCCCTTCAAAGCCGTACTCCTTTATTTGTCAATTTATCACAATCCCTGCCCCTCCACCAGTACTTACAACCCTTGATTTACGCTCTAGACTCTTAATGTGCCTTCAATATCAGTACTGAACAAAATTGAAGTGTCTGAAAACATTCGCCTTGACCATGCTTAGAACAAATGTCTAGACAGCACCTCTGTTAGTCCGTTTGTGTGTTTCAAGTATTCTGTACAGAGTGACATATCTGCCCTCACTTCTCACCTCGGCCCAGTGGCTGATGTATCTACTGACAATCTCAGTCTGAGACCCACCGGATTCACACACCATTGTAGAGTGTTTGGTGTGGACCAGTGTCGATTTTGTGTGTCTTAATAGTGTGCGGTGAGCCTTTTTTTGCACTTTAGGGCAGTACTGTTACAGAGAAGCAGAGGACTCAAACTCACAATCCTGTGACCTTATGACCCCTGTTCTGCTGATCCCCCTGTCCTCTGGGCTGGTCAGGACAACCATCGGGTTTGTGTCCCCAAGCTCATGATCTTTGGGGCGCTGCAGTCCGAATGTTCTATTGTAAATCATGCCTCCTGCTCTCATTCAGGTCCTCTTCATCAACCAAACCAGGTCCATATAGGAAGAGCTTTGCCACCAGAGCAACTCCTATCCAATCGACCACGGAAACTCTCTCCGGGGCGATTAGCCATAGAGGAACTGCAGTGTTTTGTAGTGATGTCACATCCTGTATGTGTAGACTCATCCTGGCCACTCCCActcagctgattggtcagttggtttGAAGTATTAGTAATTCCCAAAAAACTcactgtttgtgtatgtatgtgtgtgtgcgtgtgtgtgaatgtgtgtgtgcgcattcaAGGCCTGTAACTGCTTTTGTACCATGTTCTCCATGAGACTCATTAATAAACACGCAGTCTTATTTTCTACTGAA

Function


symbol description
sos2 Predicted to enable DNA binding activity; guanyl-nucleotide exchange factor activity; and protein heterodimerization activity. Acts upstream of or within pronephros development. Human ortholog(s) of this gene implicated in Noonan syndrome 9. Orthologous to human SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2).

GO:

id name namespace
GO:0048793 pronephros development biological_process
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0000786 nucleosome cellular_component
GO:0005085 guanyl-nucleotide exchange factor activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0046982 protein heterodimerization activity molecular_function

KEGG: NA

ZFIN:

id description
ZDB-GENE-090319-5 Predicted to enable DNA binding activity; guanyl-nucleotide exchange factor activity; and protein heterodimerization activity. Acts upstream of or within pronephros development. Human ortholog(s) of this gene implicated in Noonan syndrome 9. Orthologous to human SOS2 (SOS Ras/Rho guanine nucleotide exchange factor 2).

Ensembl:

ensembl_id ENSDARG00000060506

RNA


RNA id representative length rna type GC content exon number start site end site
TCONS_00013102 True 5462 mRNA 0.50 23 36638955 36663358

Neighbor


gene id symbol gene type direction distance location
XLOC_006805 cdkn3 coding downstream 17029 36612930 ~ 36621926 (-)
XLOC_006804 BX927407.1 coding downstream 26796 36587770 ~ 36612159 (-)
XLOC_006803 lgals3a coding downstream 56614 36568635 ~ 36582341 (-)
XLOC_006802 synj2bp coding downstream 72695 36557205 ~ 36566260 (-)
XLOC_006801 FP103009.1 coding downstream 93697 36537426 ~ 36545258 (-)
XLOC_006807 l2hgdh coding upstream 3304 36666662 ~ 36680531 (-)
XLOC_006808 cdkl1 coding upstream 29794 36693152 ~ 36703164 (-)
XLOC_006809 map4k5 coding upstream 42237 36705595 ~ 36761454 (-)
XLOC_006810 sav1 coding upstream 123719 36787077 ~ 36798204 (-)
XLOC_006811 nin coding upstream 136976 36800334 ~ 36844945 (-)
XLOC_006471 BX537274.2 misc downstream 26374050 10264741 ~ 10264905 (-)
XLOC_006338 rn7sk misc downstream 35812730 825904 ~ 826225 (-)
XLOC_006797 CR361558.1 non-coding downstream 239580 36399260 ~ 36399375 (-)
XLOC_006785 BX510990.1 non-coding downstream 676489 35962350 ~ 35962466 (-)
XLOC_006784 NA non-coding downstream 713471 35925042 ~ 35925484 (-)
XLOC_006779 BX663524.1 non-coding downstream 1046578 35592242 ~ 35592377 (-)
XLOC_006814 NA non-coding upstream 332275 36995633 ~ 36997760 (-)
XLOC_006815 NA non-coding upstream 346454 37009812 ~ 37012236 (-)
XLOC_006817 NA non-coding upstream 446854 37110212 ~ 37110536 (-)
XLOC_006819 AL845493.1 non-coding upstream 515244 37178602 ~ 37178716 (-)
XLOC_006829 NA non-coding upstream 864803 37528161 ~ 37535785 (-)

Expression



Co-expression Network


Homologous


species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000012_05094462_05108315 SOS2 coding CI01000012 null 5094462 ~ 5109691 (+)