dot1l (dot1l,LOC107719574,LOC107655195,LOC107586394,LOC107729667)


Basic Information

Item Value
gene id dot1l
gene name dot1l,LOC107719574,LOC107655195,LOC107586394,LOC107729667
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056720.1
NCBI id CM032089.1
chromosome length 18002998
location 11003059 ~ 11028113 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043223244.1
gtgAGCCGGTCAAGATGGCGGCGGCACTGCCGAGACGGAGCAGCCGCTCGGCTTAATCGATCATTTTCTCTAAATCACAGGGGCAGATCGGATTCAAACCGACCGAATCGTGCGGCGAAACTGTGCGAAACCAACCGCGGCCTGCGATAACCGACGTGAGATCCCATCGCGTTAAACCCGGCGTTTTTTCACGGAAATGCTCTCACTCTAGTTTGTGTCTCGTCCATTAGCCGTATTGGGGAGAATGGGAGAAAAGCTTGAGTTAAAGCTGAAGTCGCCGGTCGGAGCCGAAGCTGCAGGCTATCCGTGGCCCTTACCTATATATGATAAACATCACGATGCTGCACATGAAATCATTGAAACTATTCGCTGGGTGTGTGAAGAGATCCCAGACCTTAAGCTGGCCATGGAGAATTATGTTCTCATCGACTACGACACCAAGAGCTTTGAGAGTATGCAGAGGCTATGCGATAAGTACAACAGAGCTATTGACAGCATTCACCAACTGTGGAAAGGGACCACCCAACCCATGAAACTCAACAAGCGGCCTTCCAACGGCCTGCTGCGTCACATCCTGCAGCAGGTCTACAACCACTCCGTCACCGACCCAGAGAAACTCAACAACTACGAGCCGTTTTCTCCCGAGGTGTACGGAGAGACCTCCTTCGACCTGGTGGCTCAGATCATTGATGAGATGGAGATGATGGAAGACGACACCTTCGTGGACCTGGGCAGTGGAGTTGGTCAGGTAGTCCTGCAAGTCGCTGCAGCCACTAACTGTAAACACTACTACGGCGTGGAGAAGGCAGACATTCCAGCAACCTATGCAGAGTCAATGGACAAGGAGTTTAAGAGATGGATGAAGTGGTATGGCAAAAAACACGGCGAGTACACGCTTGAAAGGGGAGATTTCCTTTCAGAAGAATGGAGGGATCGAATAGCCAACACAAGtgttatttttgtgaataaCTTTGCCTTTGGTCCTGAGGTGGACCACCAGCTGAAGGAACGTTTCGCCAACATGAAGGAAGGTGGAAAAATTGTATCCTCAAAACCTTTTGCACCTCTTAACTTCAGAATAAACAGTCGAAACTTGAGTGATATTGGCACAATAATGAGAGTAGTTGAGCTGTCCCCTCTGAGGGGATCTGTTTCATGGACGGGGAAGCCAGTGTCGTACTATCTGCACACGATAGACCGCACCATActtgaaaactatttttctaGTCTCAAAAATCCTAAACTCAGGGAGGAGCAGGAGGCAGCCAGAAGGCGCCAGCAGAAGGACAGTAAAGAGAATAAGAGCAACACCACCACCCCGACCAAGCCCAAGGAGCACAAGCAGGCGCAGCATGACTCTGGTGGTGAGGAGCAGCGCTCAAACTCGCTCGTGCCAGTTAAACCGTCACCCAAACCCCGCCGGGCCAAGCTGCTGCCCAGGGGCCGTAAGCTCGGCAACAGGAAGCGCGGGCGGCCTAAGAAGGCTGCTGCTGCTACTGCAGCCGAGCGCAAGAACAAGAAGAGCCAGAGCGCCCTTGATCTGCTGCACGCCAAGACCCTCTCAGCGGCCCCCCCTCAGGATGCATACAGGTCACCTCAGAGTCCGTTCTATCAGCTACCTCCCAAAGTGCAGCATTATACATCGAGCCAGCTTCTCATGGGCCCCACTCCTCCAGGCCTGCAGGCTCTGCTCGATAACGTGAAGGTCCAGTACCTGCAGTTCATGGCCTACATGAAGACACCACAGTACAGGACCAACCTGCAGCAAGCCCTTGAGCAGGAAAAGctgagacacacagaacTGTCGGGTCAAGCCCAGCAGCTGCTTAACGCTTGTCATGCTCATAAGGAGAAGATCCGAGACCTTTTCCAGTCCAAACTGGAGGAGCTCGGCGTGAAGGCGGTGACCGTGGAGGACCTGGTACAGGCTCAGAAGGAGATCACGGCCCACAACATGCAGCTGAGGGAGCAGACCAAACAGCTGGAGAAGGACATGATGGAGCTCCGCGATCAGAGCCTGGTGCTGcTGAAGGCTCGCTGCGAGGAGCTCAAGCTGGATTGGGGATCTCTGTGTCTGGAGACTCTGTTGAAAGAGAAAGCGGCTCTTAGAAGACAAATCTCGGAGAAACAGCGCCACTGTCTGGAGCTCCAGATCAGCATCGTTGAACTAGAGAAGAGCCAGAGGCAGCAAGAGCTCCTGCAGCTCAAGTCTTACAACCCGTGTGAGGAGACTCCCTACCAAAAGGCCCTTCCCGGTCCAGAGCCCCGGCCCCCACTGGATTCCGACACCCCCAAACTCACCCCACACTCCTCTGTGGGGCTCAACGGCCTCAGCCCCGAGCTATCCGTCAACGGCACAGCCTCGCCGGGTTACGAGAGAGGCGGTGGCAACTCAATGGGCAAAAACGAGCTCCTCACCCGCTATCTGCCTATTTCCCCTGACCACGAAATTGTGCCGCCCACCCCAGACTCAAGAACCAGGCAGCTAGGGCAACTTCCCGACTACACCCGCTTTTCTCCAGCTAAGATCGCCCTTCGCAGGCACCTCAACCAAGATTCGGCTGCCAATCAGTTTAGAGCCCTCGGCAACATCCACCGGGGTGACGCTGGTGCTATTTCATCTCCAACTCTGGGATTAAAACATTCTTGCTCCTCACCCAGTTCAACTGATATTCAAGCGACCACAACGCCCAAGAGCACAGATAAGGAAAAGAGCCCGGCTGCCCCCGGCGACACTATAACCAGTCTGCCAATCAGCATCCCCCTCAGCACTGTGCATCCCAGCAAACTTCCTGTCAGCATCCCACTGGCCAGCGTGGTGCTGCCGAACCGCGTAGAAAGATTGaggAACACTCCTAGTCCGGTTTCGAATCCTGCAGGACAGAGTAATGGCAAGCCGCCTCTCACGCCTACCTCAGGGTATTCCTCCAGCTCAGGGTTGGTGAATGGCTCTCACACGGCCATGCTGACCGAGGACCAAGACTGTGACGCTGCATCCCCTCCCCCTCACAGCACCCCCATCATGGGCCTCCAGCCTCGTGGCTCTGGCCTCAGTCCTGCTCTGGGCACCGGAGGAGTGCTGCAGTATGCCGACGGCCCACCGAGGCTTCCACCCGAGGACGGCCATGACCGGCAGGGCCCCGAGTCTGACACGGAGCCCTTGGACAGCGAGGCCCGTCGCCGTATCTTTTTCTCCTcgtcctcttcttcctcctcatcttcGTCCTCCACAGGAGGCTCAAGGCTCCACCACGGGTCGGTAAAGCAGGGTCACCATCATCACAGTAAgcaccatcaccatcatcaccaccaccatcatcactCTCCGAGCTCCCACAGCCAAGAGGGGCGGAAACGAGGGCGTCGGAAGCGCAGCTCTTCTGGCGCCATTCCCCTTAGCGTATCCCCCAAAAGACGGCCATTTCCAGGACTTGGCTGCTCAAGCCATTCTTCTGGATCACCACTTAATATCAATTCAATGGTGAACAACATAAACCAGCCTTTGGAGATCTCGGCCATCTCTTCCCCAGAGCAGTCGGGACGAAGCCCATGCGGGACAGATCTAGATCAGCCTCCTGTGCTCAAAAGAGAGCGTCCCCTGGATCTCAATAACACAGGTCGTTATTCTTCCACTCCTAGTTCAGATGAAGAGGGCGGCAATTTTGCCCCGGACACCTCTAGTTCAAGCCGAATTGAGAGGAAAATCGCCACCATTTCCTTAGATCGAGATGGACCCATCAGAGATGTGGAAAGGGGCTCGCACGGACGTAAATCAGGTGCCAGTAGCGTGAGTAGTGAGGTATCATCTTCCTCTGGAGCCAGCAAGTGGAAATCCACCTTCTCCCCAATCTCTGACCCCAAACCAACTCCTCCGGATCTCCGCCAGGGTGGCTCGCCATTCGGTGTGAGTGCTTCCCGATGCGGTACGGACTCTGACTCGGACCAGAAACCGCAGAGGAGAGGGGGACGTGAGCGTGAGGCCTACGGGAACTCGAACCTCTTCCTCAGTCAAGATGGCGGCGGTCGCTCAGTCGTCAGCTCGTCTGAGCGGCCGCTGCAGAAACAGAAATCGCGTGAGTGGGACCTGAAGTCTGTAAGTGGATTGGCCAGCCAGAACCTCTTTATATCCGCTGCGGCCAGTGGAGGCATCTTGAGTGGGAAAGTGGGTGGGGCTGCCACAGTTTCGTCCGCCTCCTCAGTCGGACAGTACTTCCCCCTGGCCGGGGCTTCGGTCCTACAGTCCTGGACGCCCGGACCGGCCACCGGCGGAGCTCCCCGATTGGTCAACGGACATTCAGCGCTCAGCAGTTTCTCCAGCGCCGGGCTGGCAGGGGGCGCTGCAGGAGGGATATTTCACCACATGGTGCCTTCAGTCTCCTCACAGCAGTCTGGGGCCAATCTCCCGGGCCCCGGGGCCCTCAGTTCCCAGCAGAGGCATCTGGACGCGAACCCCAAAGCGGGGGCCTCGTTCTTGGCCTCTGGCCCCTCTCAGCACAGCCGCACACAGACAGTCCTACACGCCCCTCCCCGCCCACCCTCGCCCTCCCTCCGCCCCTCTCCTCCTGAGCGCGCGTCCTCCGCCTCCACCCCGTCCCAACCTTCCTCCCCGCGCTCCGAGCGCCACCAGTCCTCAAGGCCGCAGTCGTCCCTCCCcgcctccacctcctcctccccaTCTCTGGCCGCCACATCTGCTTCCTCCGCCTCCTCCGCTTCCTCCCGGCCCTTCACAGTGCACTATCCCCTGCACCTGCCGCCTCCCCACCCTCCCGGCAGCGCAGGTTCAGGTGGGGCTGGGACGTCCTGGAGGACTCTGGGTATGCAGGCGTCCTACGCGGCGGCCTCGCAGATCCCCGGCAATCGCCCCAGATAGGCCACGTCCGGGCGTAGCAGGGTGGGGGGAGGGTGGGGGCGGTTTGACGTGGAAAGTAGACTATTACTAGACGGACACAGGGAAGCTACTGCGCTCTGCCAGCTCTAATGTTATGAGTCCCAACAAGGTAACTGAAGAAATCTACCTCAACCCAACATAACCTATGCAATGGACAGGTGTGGACCAATGGGCTCGACTCGCTCACCGGTGCTCAAACGTTTGCTAAAAGACGCCACTGTAAAACTGGCATGGGTATCAGAACTTATCACAGGTGcagcttacacacacacacacacacacacagagcccctGAACCCCATTCAGATCGACACAGTATGCGGCTTCCTTGTTTTCCCCGAGTGTTTTAAGGCGACACCATGTTGGGCCGACGCTAACAGCCGTTCATCAGTTATTGTGAGTTTAACACGGCCTTACCGGTGGATGCTTTACTTAATTTGCAGCCATCTTTTGGTGGATTCACAGTCGATGACGCAGGAAGCGGTTTTTAAATGTCAGGAATATGATTACAGTCAGTCTGGTTTTAATACGCACTAAAAAAAGAGGCTAGTGTGAATCTCTGTAACCTCGCTGCTGTTATCAGCGGAAAGAAATGTGGCTTTTTGTGCTCGACGACTCCTATTCGGATGGTCTCCGTGAAGCCCCTGGAGCCTGTAGCGGGACGTCACCCGTACAGCCGGAGCTTGTGCTGTGAAATCGTTGTTAACGCGTCTGTCAGCTTGGCTTGGGCATTTTAACTTCTCCTCATATTAATTATTTGCCTTGTAAGCTGAAATATATAGGAAACCACAAGCTGCTTCTGTATAAGGGGGAATCTCTAAAGTAATATTTCACCTCAAAGACGACGTTAACGCTTCATATCGAAACAGTTACACACATTTTCCCAGATTctcattataataatgtaaaatatgcatatgaTGTGCATCGGTCGTGTTCTGTAATTCATTCAATGTTTTTAGAATTAATAAATTGCAATACTATTTTGAATTgcagtatgtttgtttttttgtttttttttttttgtaaaaatgtttataacatttttgcattataatattagGAGGTGAAATTGATTGTCATAAATCAAGCCACTACAAAAATTAGTATTAGCGTTGAATTTTTTTCACgtcatttttggggtgaaatatgaccaGGCACGTTCTTGATGGGCTTCACGAGATGCATCGGTTAAATaatttcgttttattttttacactggACAATTAACCTGTGGAGCTGTTAACGACGAACGTATCAAAAcagcatgtcatttttaaaatgtaagcttttattaatcaaagggaaaaatgttcattttacatgcatgtaaaaaaaaaaaaaaaaaaaaaaatgaaaccaacACACACGCACCTTCCAGGAATACACGATTAAAAGCCAATCTGCAGGGAGAGAAGCGGTTAGAGCCACAGAATGAGTGACAAGCCTGTAAGGAGCTGTTGAATCAGGTTAGTTTCTTTAACTAGCAGATCTTATTGAATCACTACGTTTACCGTTCGCTTTTGGTTTAGGGCCCTGTTTCAATACTCAAGCTTCCATGTTCCTAACGGTTACTGCTGAACCTTTAATACGATGCACATATTTTGTTCAATCGGAACGCGGTGTCTTACGCGGTACAGGCTTATTCAGGTGAATCTGGTGCTGAACCATGTTCCTCGCAGATTTCATAGGCGTTTTCCTTCGGATGACCAAATCCGATGCCGTCGTGGTGCTCTTCGCAAACCTGGAAAACCAGCACGCGCTcgtacatacaaacacactgatGAAAAGATGTACACACACTGGGAAATTGCAAGATCACAAAACGACATAAAACTACTGGGCAACTTCAACTCAtccttttgtttctctcttatTGCTttgtgtatgattttttttttttctgtactgtGAATGGTAGTCTCTCTCGGACTGTGtaattgtgtatataatttGGGTTATTTATCGTTTtaattttctgtctttttttttgttatttcttttgGTTTGTGATTGCTCTCGTTTTGTATCGGAGCAGAGCACAACATGTGCAAAGTGTATGTACTTGActcagtctaaaaaaaaaaaaatggtgctaCAATCTGTACAACTTTAGACTGTGCTTATTTATATTAAGATCATCATCGACAACGacaacaaaagaaatgaataaagatTTTTGGTGCTTCTTTTACACAGGGATGTTTGCGAGCCTTGcggcatttattttttcaatatttataatgtattatttggcGCCCAGCATGAAGCATCCCCTGCCTGTTTGGATCAGTGCCGTTTTTATATACGAGAAACACCTTTTGGTCTTAATCGAACTTAAAGAAGCATGAAAGTACATTGCAGAACTTTATAGGACGATATAACTTTTTCATTTGAAGTATTTACTTCAATGGTGCTCCGAAATCGACCTGCGTGACGGGTAGTGAATGCTTTGAATCACACGCGCGGCACACTGTTGAAATCGGTGCCGCGTGGCGTTTCGTAACAATTTTTGATTTCTCGTAAAGGAGAACACGTGCTAAGCCTGTTTTGCTTACCGTCTTGGGCCCGTACGGCTCGGTGCTGTTTCTTAAAACCGCGGTTTTTCTTCGCAGATGTAACGCAGACAGCTTCATCTTACACAAACTGGTGCTGACGTTCACGCAGATGTCGAAAATGAATACGCCCGTACCAAAACCTACGATCCACTATCGAAGCCTGTCCTAGAGCGCGTCATGTAAACCTAGAGTTTGAGCCTATTGCGTATCGTGATGTAAAGTTGTTCTGATGTGACCAGTCGTAGATTTGGCTAGTGTTTTTGTCAGTTGGCTAGTACTAGTGGTTGACCGATATGGGTTTTCCAATGACTGTTATCATATCTAGAGAATAGgctaatataatgttatttaatgtgttattcTGCGGAACACGAAAATGCTCGTAGAACGAAAGGCAAAGGGGTCCAAAATTTGGAAACCATTGACTTTTTGTATGAGATTTCCGCCTGCCCGATATATCGGTCTATCACTAACTGGTacagcgttaaaaaaaaaaaataattttttaaattgtcattgGCGTACAACATCGCCAATTTGAAGACAAAGCAGGAGTGGACGTCCTCATTGTTTTGCGTCCTTATTtccttttattgtgtttttgttgcttaAGTATGTGCTCAAGGAAAATTCAACCTCACCTAAGCTTTAGTCAGAATGCTGTGTAATAGACTATggtgtataataatattaaaaaacaaaacaaaaacaatgtgtaAATGGTCTTTCTCCAATTAACACGAGGACATTTGGATGAAATAGGATATTGACCAGTACATGAGTACATTGTTACCAGCActgagggtttttttgtttttgtttttttttgttttttaatagcaaTTAATAATCATTGTTAATGTTACCTGTTTTAATGGCCAATTTGTGTTTTGATATCTTTGCGACTGTTTATCAATGATGGTTTTATGATTTCATGATCCTGACCATTTGGATACTCTATAAAACAGTAAGGTGCTCTCCTACACTTTAAACAAGGAAAATGCAGCTATAAAAATTCAAGCACCTCTTGCATTACAAGGAgtaactatttaataaaatcagcgCAAGCTTTGCTTGTTTTACTTTG

Function

symbol description
dot1l Predicted to enable histone methyltransferase activity (H3-K79 specific). Acts upstream of or within canonical Wnt signaling pathway and intestinal epithelial structure maintenance. Predicted to be active in nucleus. Is expressed in hindbrain; intestine; and midbrain. Human ortholog(s) of this gene implicated in mixed phenotype acute leukemia. Orthologous to human DOT1L (DOT1 like histone lysine methyltransferase).

NR:

description
PREDICTED: histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X3

GO:

id name namespace
GO:0060070 canonical Wnt signaling pathway biological_process
GO:0060729 intestinal epithelial structure maintenance biological_process
GO:0003677 DNA binding molecular_function
GO:0018024 histone-lysine N-methyltransferase activity molecular_function

KEGG:

id description
K11427 DOT1L, DOT1; [histone H3]-lysine79 N-trimethyltransferase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043223244.1 True 8536 mRNA 0.50 29 11003059 11028113

Neighbor

gene id symbol gene type direction distance location
amh LOC107729672,LOC107676960,LOC107593309 coding downstream 2073 10997306 ~ 11000986 (-)
org LOC107729678,LOC107655182,LOC107719657,LOC107676951,LOC107586460 coding downstream 19071 10981892 ~ 10983988 (-)
lingo3a LOC107719577,LOC107655199,LOC107596880,LOC107729688,LOC107676981,LOC107586392 coding downstream 40716 10937626 ~ 10962343 (-)
atp8b3 atp8b3,LOC107676946 coding downstream 96038 10892097 ~ 10907021 (-)
pias4a pias4a,LOC107586389,LOC107655204,LOC107596878,LOC107676972 coding downstream 150880 10843805 ~ 10852179 (-)
ell ell,LOC107729685,LOC107719573,LOC107655162,LOC107586435 coding upstream 3609 11031722 ~ 11061071 (-)
fkbp8 fkbp8,LOC107676977,LOC107719572,LOC107699404,LOC107729668,LOC107586436 coding upstream 34652 11062765 ~ 11075653 (-)
ssbp4 ssbp4,LOC107719571,LOC107676978,LOC107729707 coding upstream 49483 11077596 ~ 11128670 (-)
tmem59l tmem59l,LOC107719570,LOC107676980,LOC107729706,LOC107699406,LOC108439280 coding upstream 134504 11162617 ~ 11175995 (-)
ankrd24 ankrd24,LOC107729675,LOC107719567 coding upstream 221875 11249988 ~ 11266155 (-)
G151704 NA non-coding downstream 69638 10932994 ~ 10933421 (-)
G151702 NA non-coding downstream 70550 10930882 ~ 10932509 (-)
G151668 NA non-coding downstream 218817 10783638 ~ 10784242 (-)
G151616 NA non-coding downstream 287102 10715425 ~ 10715957 (-)
G151612 NA non-coding downstream 293309 10709202 ~ 10709750 (-)
G151762 NA non-coding upstream 15884 11043997 ~ 11046227 (-)
LOC122327759 NA non-coding upstream 127674 11155787 ~ 11159729 (-)
G151774 crlf1b,LOC107676985,LOC107729674,LOC107719637,LOC107577518 non-coding upstream 148450 11176563 ~ 11179432 (-)
G151775 NA non-coding upstream 151809 11179922 ~ 11180390 (-)
G151773 NA non-coding upstream 156117 11184230 ~ 11185919 (-)
oaz1a oaz1a,oaz1s,oaz1,LOC107719576,LOC107655198,LOC107586434 other downstream 8107 10935052 ~ 10994952 (-)
micos13 si:dkey-78l4.14,LOC107596903,LOC107719663,LOC107586453,LOC107675912,LOC107655188 other downstream 580705 10419127 ~ 10422354 (-)
polrmt LOC107687709,LOC107728563,LOC107569934,LOC107655172,LOC107719647,LOC107569035,LOC101483880 other downstream 681396 10282022 ~ 10321663 (-)
G151425 NA other downstream 1019912 9957811 ~ 9983147 (-)
gpx4a gpx4a,LOC108429535 other downstream 1500053 9498669 ~ 9503006 (-)
rex1bd si:ch211-87h14.3,clg08h19orf60,cssa23h19orf60,LOC107676986,LOC107729673,LOC107593355,LOC107719569,LOC108439285,LOC103025814 other upstream 146030 11174143 ~ 11188692 (-)
cks2 cks2,LOC107699408,LOC107593315,LOC107729701,LOC103026129,LOC108230759,LOC105927846,LOC106584418 other upstream 201861 11229974 ~ 11231249 (-)
gna11a LOC107717982,LOC107676956,LOC107586405,LOC107699416,LOC107719558 other upstream 437739 11465852 ~ 11490654 (-)
LOC122327290 LOC107655377,LOC107755342,LOC107565170,LOC107659327 other upstream 765460 11793573 ~ 11804698 (-)
LOC122327182 NA other upstream 813475 11841588 ~ 11845142 (-)

Expression


Co-expression Network