pak2b (pak2b,pak2,LOC107741800,LOC107678112,LOC107679089)



Basic Information


Item Value
gene id pak2b
gene name pak2b,pak2,LOC107741800,LOC107678112,LOC107679089
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056720.1
NCBI id CM032089.1
chromosome length 18002998
location 2132741 ~ 2142363 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043223384.1
CGCACCGGAAGCAGTCGCTGTCTGTTTGCTGCAGGCGAGGGCAGAAAGAGACGCTGCTGGGCGCCTCCCCTTCCCCAAACCAGCACAAAAAAGCTGCCGAGACCAGCGGTACGCGGCGCACGACCCATCGGACGGGGCTCCCGCGTCGCCTCACGCCTCTCCCCGGACAGAGCAGCTCCCCCGCGGCCCGCCGGAGCGCGTCGCGCCGCACTTCGAGCTCCGCTTCACAGCTCTAACTCCTCCTTTTCTTTATCTCCACCCTCGATCGCTCCCCTCCACCCGCCCACTCCtccgctctttctctctgtgctcTCTCTCTGGACCATGTGTGACAATGGGGACGTGGAGGACAAGCCGCCCGCTCCGCCCGTCAGGATGAGCAGCACCATCTTCAGCGGCGGAGGCAAAGACGGCCTGGCGGCCAACCACAGCTCCAAGCCCCTGCCCTCGGTGCCCGAGGAGCGCAAGCGCAACAAGATCTACTCCATCTTCTCCGGCGCCGAGAAGGgcGGCCGAAGGAAAGACCGAGATAAAGAGCGTCCCGAGATCTCGCCGCCGTCGGACTTCGAGCACACTATTCACGTGGGCTTCGACGCCGTTACCGGAGAGTTTACAggGATGCCCGAGCAGTGGGCGAGGTTACTGCAGACCTCGAACATCACCAAATCAGAGCAGAAGAAGAATCCTCAGGCCGTCCTCGACGTGCTCAAGTTCTACGACTCGACAGGAAACGGCCGACAGAAGTACCTCAGCTTCTCCTCAGAGAAGGACGGCTTTCCCTCGGCTGAACAATCACCTGTGAAGAAATCCCCAGAGCCCTCGTCTCCAGTCAAAACGGtggatgatgaagatgacgatgaCGACGAGGAGACGCCGCCACCTGTGGTCGCCCCACGACCAGAACACACCAAGAGCGTATATACGCGACCATCGGTCATCGACCCCCTTCCTCCTCCGGTGACGTCTCCGGACAGCGATGTCGCGTTGAAGGCTGGCGACCGACAGAGACCCAAAAAGGGCAAGATGACAGACGAAGAGATAATGGACAAGCTCCGAACTATAGTCAGTATTGGAGatccaaaaaagaaatatacacGATACGAGAAGATCGGACAAGGGGCTTCGGGAACGGTGTTCACTGCCATCGACGTTGCTACTGGACAGGAGGTGGCCATCAAACAGATTAACCTGCAAAAGCAGCCCAAGAAAGAGCTTATCATCAACGAAATTCTCGTCATGAAGGAACTGAAGAATCCAAACATTGTCAACTTCTTAGACAGTTTTCTGGTAGGTGAGGAGCTGTTTGTCGTGATGGAGTACTTGGCTGGTGGCTCGCTCACAGATGTCGTAACAGAGACCTGTATGGACGAGGCTCAGATCGCCGCTGTATGCCGAGAGTGTTTGCAGGCTCTGGAGTTTCTTCATTCTAATCAAGTCATTCATCGAGACATCAAGAGTGACAACGTGCTACTGGGAATGGACGGTTCTGTCAAGCTCACGGACTTTGGATTCTGTGCTCAGATCACTCCCGAACAGAGTAAGAGGAGCACCATGGTGGGAACGCCATATTGGATGGCTCCGGAAGTCGTGACGCGCAAAGCCTATGGACCCAAAGTCGACATCTGGTCCTTGGGCATCATGGCTATCGAGATGGTGGAGGGAGAGCCGCCGTACCTCAACGAGAATCCACTGAGGGCGCTCTACCTGATTGCCACCAATGGGACTCCAGAGTTGCAGAGTCCTGAAAAGTTGTCGCCAATCTTCCGGGACTTCCTGAGTCGCTGTCTGGAGATGGATGTGGAGAAGAGGGGTGGTAGCAAAGAGCTTTTGCAGCATCCCTTCCTGAAGTTGGCCAAGCCTCTCTCGAGTCTCACTCCTCTGATTTTGGCGGCCAAGGACGCTATGAAGAACAACCGCTAGCTGTGCCCAAGAGCGCAGCGGACTGCTGAACACTCTCGAAATCTGTGCcaggtgtttttgtttttttcgttaatttttttttttttttttttttttacaagtgtGTCAACAACATATCAGTGTTGCCAAAACAAAAACTCTGAGCATTTCATTTGGGTCTTTGCCTGTTTTTAAACCTGTATTGACCCCTGTGGTGTTGGGGGACATTAGATGTTCTCCTCGTCCTCCTGCTCTCGTTAGATTCTTGTGGGACTTTGTCTGTGTTTTACGTATGAACTCTTCTACTCTTTGGCTTCTCTAGACCTCGTGTGTTCCATAATTGGTCACCAGAATCAATTATGGTGATTTCAAATCCAGCTGGAGatcttttgttagtttttttttctgtagccaGAATCACGACTGAAAACTGTGTAGCCTACTCCTGTTCTTGACCCGAAGGGAAGAGCACCTTACCGATACACGCCAACTGCGAGCAGTGAATGATTTTTGTAGTCACTTGTGCCTTTGTTGTTATTCCAGCAAACACCTTTATACTCTGTCTGAAGGGGCAGGTTCTTGCCATTGAACTTCCTCTAACCTGAGACAAAACTTTCATGTTATGAAATGTGTATATGACGTACTTCGAAGAAGAGTAGCATTTCAGTTGATGTAGTTAACCAAAAGCAGGATGCGTAGATTAGATAggtgtatgtttgtgtacatgaacacttttcttgttgttttagTAACTAACAGTTTATTACGAAGTAAATGCAGTTGTCAAGAAGTCACAATGTAAGAATTGATAactatttttatgcttttcagCCACTTGTTTTGCAAGTAAAAGCCGGATTCCTGCAAACTTCTGTGAACAATACAGTCATATTGAAACATTGTGTACATCTCTTGTTCTTCATTAAAAGAGGACTTGAAACTTGA
>XM_043223385.1
CGCACCGGAAGCAGTCGCTGTCTGTTTGCTGCAGGCGAGGGCAGAAAGAGACGCTGCTGGGCGCCTCCCCTTCCCCAAACCAGCACAAAAAAGCTGCCGAGACCAGCGGTACGCGGCGCACGACCCATCGGACGGGGCTCCCGCGTCGCCTCACGCCTCTCCCCGGACAGAGCAGCTCCCCCGCGGCCCGCCGGAGCGCGTCGCGCCGCACTTCGAGCTCCGCTTCACAGGACAAGCCGCCCGCTCCGCCCGTCAGGATGAGCAGCACCATCTTCAGCGGCGGAGGCAAAGACGGCCTGGCGGCCAACCACAGCTCCAAGCCCCTGCCCTCGGTGCCCGAGGAGCGCAAGCGCAACAAGATCTACTCCATCTTCTCCGGCGCCGAGAAGGgcGGCCGAAGGAAAGACCGAGATAAAGAGCGTCCCGAGATCTCGCCGCCGTCGGACTTCGAGCACACTATTCACGTGGGCTTCGACGCCGTTACCGGAGAGTTTACAggGATGCCCGAGCAGTGGGCGAGGTTACTGCAGACCTCGAACATCACCAAATCAGAGCAGAAGAAGAATCCTCAGGCCGTCCTCGACGTGCTCAAGTTCTACGACTCGACAGGAAACGGCCGACAGAAGTACCTCAGCTTCTCCTCAGAGAAGGACGGCTTTCCCTCGGCTGAACAATCACCTGTGAAGAAATCCCCAGAGCCCTCGTCTCCAGTCAAAACGGtggatgatgaagatgacgatgaCGACGAGGAGACGCCGCCACCTGTGGTCGCCCCACGACCAGAACACACCAAGAGCGTATATACGCGACCATCGGTCATCGACCCCCTTCCTCCTCCGGTGACGTCTCCGGACAGCGATGTCGCGTTGAAGGCTGGCGACCGACAGAGACCCAAAAAGGGCAAGATGACAGACGAAGAGATAATGGACAAGCTCCGAACTATAGTCAGTATTGGAGatccaaaaaagaaatatacacGATACGAGAAGATCGGACAAGGGGCTTCGGGAACGGTGTTCACTGCCATCGACGTTGCTACTGGACAGGAGGTGGCCATCAAACAGATTAACCTGCAAAAGCAGCCCAAGAAAGAGCTTATCATCAACGAAATTCTCGTCATGAAGGAACTGAAGAATCCAAACATTGTCAACTTCTTAGACAGTTTTCTGGTAGGTGAGGAGCTGTTTGTCGTGATGGAGTACTTGGCTGGTGGCTCGCTCACAGATGTCGTAACAGAGACCTGTATGGACGAGGCTCAGATCGCCGCTGTATGCCGAGAGTGTTTGCAGGCTCTGGAGTTTCTTCATTCTAATCAAGTCATTCATCGAGACATCAAGAGTGACAACGTGCTACTGGGAATGGACGGTTCTGTCAAGCTCACGGACTTTGGATTCTGTGCTCAGATCACTCCCGAACAGAGTAAGAGGAGCACCATGGTGGGAACGCCATATTGGATGGCTCCGGAAGTCGTGACGCGCAAAGCCTATGGACCCAAAGTCGACATCTGGTCCTTGGGCATCATGGCTATCGAGATGGTGGAGGGAGAGCCGCCGTACCTCAACGAGAATCCACTGAGGGCGCTCTACCTGATTGCCACCAATGGGACTCCAGAGTTGCAGAGTCCTGAAAAGTTGTCGCCAATCTTCCGGGACTTCCTGAGTCGCTGTCTGGAGATGGATGTGGAGAAGAGGGGTGGTAGCAAAGAGCTTTTGCAGCATCCCTTCCTGAAGTTGGCCAAGCCTCTCTCGAGTCTCACTCCTCTGATTTTGGCGGCCAAGGACGCTATGAAGAACAACCGCTAGCTGTGCCCAAGAGCGCAGCGGACTGCTGAACACTCTCGAAATCTGTGCcaggtgtttttgtttttttcgttaatttttttttttttttttttttttacaagtgtGTCAACAACATATCAGTGTTGCCAAAACAAAAACTCTGAGCATTTCATTTGGGTCTTTGCCTGTTTTTAAACCTGTATTGACCCCTGTGGTGTTGGGGGACATTAGATGTTCTCCTCGTCCTCCTGCTCTCGTTAGATTCTTGTGGGACTTTGTCTGTGTTTTACGTATGAACTCTTCTACTCTTTGGCTTCTCTAGACCTCGTGTGTTCCATAATTGGTCACCAGAATCAATTATGGTGATTTCAAATCCAGCTGGAGatcttttgttagtttttttttctgtagccaGAATCACGACTGAAAACTGTGTAGCCTACTCCTGTTCTTGACCCGAAGGGAAGAGCACCTTACCGATACACGCCAACTGCGAGCAGTGAATGATTTTTGTAGTCACTTGTGCCTTTGTTGTTATTCCAGCAAACACCTTTATACTCTGTCTGAAGGGGCAGGTTCTTGCCATTGAACTTCCTCTAACCTGAGACAAAACTTTCATGTTATGAAATGTGTATATGACGTACTTCGAAGAAGAGTAGCATTTCAGTTGATGTAGTTAACCAAAAGCAGGATGCGTAGATTAGATAggtgtatgtttgtgtacatgaacacttttcttgttgttttagTAACTAACAGTTTATTACGAAGTAAATGCAGTTGTCAAGAAGTCACAATGTAAGAATTGATAactatttttatgcttttcagCCACTTGTTTTGCAAGTAAAAGCCGGATTCCTGCAAACTTCTGTGAACAATACAGTCATATTGAAACATTGTGTACATCTCTTGTTCTTCATTAAAAGAGGACTTGAAACTTGA

Function


symbol description
pak2b Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within blood vessel development. Predicted to be active in cytoplasm. Is expressed in axial vasculature; endoderm; and nervous system. Human ortholog(s) of this gene implicated in ductal carcinoma in situ. Orthologous to human PAK2 (p21 (RAC1) activated kinase 2).
pak2 Enables several functions, including enzyme binding activity; identical protein binding activity; and protein tyrosine kinase activator activity. Involved in several processes, including cell-cell junction assembly; negative regulation of stress fiber assembly; and regulation of apoptotic process. Acts upstream of or within protein autophosphorylation. Located in cell-cell junction and cytosol. Implicated in ductal carcinoma in situ.

NR:

description
serine/threonine-protein kinase PAK 2

GO:

id name namespace
GO:0042981 regulation of apoptotic process biological_process
GO:0006950 response to stress biological_process
GO:0000910 cytokinesis biological_process
GO:0006468 protein phosphorylation biological_process
GO:0001568 blood vessel development biological_process
GO:0030036 actin cytoskeleton organization biological_process
GO:0007409 axonogenesis biological_process
GO:0000278 mitotic cell cycle biological_process
GO:0005737 cytoplasm cellular_component
GO:0005524 ATP binding molecular_function
GO:0004702 obsolete signal transducer, downstream of receptor, with serine/threonine kinase activity molecular_function

KEGG:

id description
K04410 PAK2; p21-activated kinase 2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043223384.1 True 2844 mRNA 0.51 15 2132741 2142363
XM_043223385.1 False 2726 mRNA 0.50 15 2132741 2142363

Neighbor


gene id symbol gene type direction distance location
aqp12 NA coding downstream 3776 2124590 ~ 2128965 (-)
trnai-aau_113 NA coding downstream 4806 2127862 ~ 2127935 (-)
LOC122327992 NA coding downstream 8772 2120589 ~ 2123969 (-)
LOC122328100 NA coding downstream 18498 2112781 ~ 2114243 (-)
LOC122328124 NA coding downstream 169514 1959836 ~ 1963227 (-)
pigx NA coding upstream 675 2143038 ~ 2146500 (-)
ing5a ing5,ing5a,LOC107574595,LOC107678097,LOC107548837,LOC107679074,LOC108424972 coding upstream 6315 2148678 ~ 2155381 (-)
lmnb2 lmnb2,LOC107679080,LOC107678108,LOC107744643,LOC107741802 coding upstream 64120 2206483 ~ 2217633 (-)
lonp1 lonp1,LOC107744642,LOC107679084,LOC107548847,LOC107678106 coding upstream 79476 2221839 ~ 2231871 (-)
gpr35.1 LOC107717171,LOC107678099,LOC107580869,LOC107678091 coding upstream 108848 2251211 ~ 2255460 (-)
LOC122327838 NA non-coding downstream 58 2129531 ~ 2132683 (-)
G148679 NA non-coding downstream 561 2129842 ~ 2132180 (-)
trnag-gcc_103 NA non-coding downstream 1458 2131213 ~ 2131283 (-)
trnad-guc_17 NA non-coding downstream 1783 2130887 ~ 2130958 (-)
trnai-aau_114 NA non-coding downstream 2045 2130623 ~ 2130696 (-)
G148707 NA non-coding upstream 13893 2156256 ~ 2156817 (-)
LOC122328197 NA non-coding upstream 376074 2518437 ~ 2524302 (-)
LOC122327855 NA non-coding upstream 384731 2527094 ~ 2563223 (-)
G148749 NA non-coding upstream 449209 2591572 ~ 2592729 (-)
G148860 NA non-coding upstream 555750 2698113 ~ 2759687 (-)
LOC122328032 NA other downstream 16558 2114320 ~ 2116183 (-)
G148613 NA other downstream 468114 1661185 ~ 1664627 (-)
G148574 NA other downstream 478401 1643710 ~ 1654340 (-)
LOC122327995 NA other downstream 506834 1580290 ~ 1625907 (-)
gpr35.2 NA other upstream 102268 2244631 ~ 2250561 (-)
LOC122327369 LOC107566359,LOC107727552,LOC107702633,LOC107698598,LOC107549380,LOC107733351,LOC107733325,LOC107566366,LOC107727554 other upstream 909037 3051400 ~ 3065177 (-)
dnase1l4.1 zgc:101000,LOC107566350,LOC107712182,LOC107702655 other upstream 1081785 3224148 ~ 3232213 (-)
cers5 cers5,LOC107698577,LOC107590873,LOC107694004,LOC107718462,LOC107712190 other upstream 1113033 3255396 ~ 3273051 (-)
si:rp71-36a1.1 NA other upstream 1183212 3325575 ~ 3366122 (-)

Expression



Co-expression Network