pink1 (pink1,LOC107714979,LOC107697909,LOC107751829)


Basic Information

Item Value
gene id pink1
gene name pink1,LOC107714979,LOC107697909,LOC107751829
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056721.1
NCBI id CM032090.1
chromosome length 19062720
location 17778474 ~ 17784124 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043225105.1
ACCAATGAGCGTTACGTAAACACCGTCCTTGAGGAAATAATGTAGGGACAAGTCGGCTCGGTAAACAGGGTCATCTTCGTGAATTGTAGTTCTTTACTCGGCTCAAAATGTCAGTGAAACATGCTCTCGGTCGGGGGTTGGAGCTGGGGAGGTCGCTTCTCCAGCTGGGGCTGTTCAAACCAGCCGGCCGCGTGGCAGCGAAGCTCCGCGGCGAGAGGCTGCGTGTGTCCCGCTCGACCCGCACCGTCCAGCCGCAGACCTTCCTGCCCGCTCGATACCGCTTCTTCCGGCTGTCTCTCAGCGGGCTGGCCGCGCAGCTCCAGTCTGGGGCTCTCAGGAGAGTGGCTGGAGGTGGTGCTCCCAGAAACAGAGGTGTTTTTCTGGCTTTTGGGCTGGGTTTGGGGCTGGTTGAACAGCAGCAGGAGGAGGACAGGACAAGCGCTGCTCTGTGTCGGGAGATACAGGCCGTATTCAGAAAGAAGAAGTTTCAGACCCCTCTGAAGTCTTTTACATCGGGGTACAAGTTGGAGGACTATGTGATTGGGAAACAGATCGGGAAAGGTTGCAACGCGGCGGTGTATGAGGCAGCGGCTCCGTTCTCGGCCCCTGCGGAGAGCGGGAAGTGTTCACTGGTGGAACTCAACCAGAAAGAAACGGATGATGACGATAAGACAGCAGGACCCCTTCGATTCTCAGCTAAACCCAGCTTTCCCTTAGCTGTCAAAATGATGTGGAACATTGGGGCTGGTTCATCAAGCGATGCCATTCTGCGCTCTATGTCTATGGAGTTGGTTCCTGCTTGTCCACAGGCTTTAAGGAAAGAGCAAGGAGAGATCGCTTTAGATGGCCGTTTTGGAATGGTGCCTAAAAGACTGACTGCTCATCCCAACGTGGTCGCAGTGTACCGGGCCTTCACCGCTGAGGTCCCGCTGCTGCCCGGAGCTCAGGAGGAGTACCCCGATGTCCTGCCTGCCCGGCTCAATCCGCTGGGTTTAGGCAGCAATCGCACGCTGTTCCTGGTCATGAAGAATTACCCGTGCAGCTTGCGGGAGTACCTGGGGGTGTGTGTGCCCGACCGGATGCAGGCGTCTCTCATGCTGCTACAGCTGCTAGAAGGGGTGGATCACCTGGGCAAGCAGGGCATCGCTCACAGAGACCTCAAATCAGACAATGTGCTCCTGGAATTTGACAGCTctgGGTGTCCCAGACTGGTGATCACTGACTTTGGCTGTTGTCTGGCAGAGGATTTTGGCCTCAAGCTGCCCTTCAACAGCTGCTGGGTTAACAGAGGAGGAAACGCCTGTCTGATGGCACCTGAGGTGGCCACAGCAGTTCCAGGACCTGGGGTGATGATAGATTACAGTAAAGCAGACGCCTGGGCTGTAGGTGCCATGGCCTATGAGCTCTTCGGTCAGCCGAACCCCTTCTACAGCTCAGAGGGACTGGAGAGTCGCAGTTATCAGGAACAACagcttcctcctcttcctgctgCTGTACCTGAGGATGTACAGCTAGTAGTGAAGCTACTGCTGCGCAGAAACACTCATAAGCGGCCCAGTGCACGTGTGGCTGCTAACATGCTTCACATGAGCCTGTGGGGCAGGCGAGCGTTGTCCAGCTTGGATCGGACCAGAATGGACGAGCTGTCGGACTGGCTGCTGTGTCAGTCAGCTGTGGTGCTGCTGAAGGGCCGAGGGTCCGGCGGGAGCTCCGTGGAAGCCGAACTCCAGAGATGCTTCCTCGCCAACATAGACCTGGAGGACCTCCGCTGCGCAGCCCGCTTCCTCGCGTACGGACAAGAGCAGTGGAAGTCCCTGCTAGCACACTACACTGACCCCTAGTGAGCGAGGGAGTGCTCACTAGAGAAACAAGCACAGTTGCACAGCTTTCGTTTTATTGTCCATCGCTGACGTATTTTGAAAGGATGGCAGTTTATGCATTTGCACTTTTAACTATGTACTTTATGCTGTTGATGACTCTTTAGAATAACAGCTTGAAGCAGGTACAAATTCATGCATAATGTAGTGCATAGTATACTGAACATCGCTTTTATAATGAAGGcggaataaataaatggatgtaTTTTCTGACagtatatttaatgcaaattagattttaacTTTTGGGAACTGATTGCATCGGTCGGTCGGAGGGGTCGAAAAAGCCTTTGGGATGTCGCTTCAGGGATTGAGCGAGtgattatatttttgaatgagTTCGCCGTTGCAATCTTTGGAGTAAGTTGTTTTGATGAATTGTGTAATAATACAATCGTGCATGTGCATTAAACTTAAACGGGCTGTATTTTCAAGGCACTTTATGGAAAGGAAATTTGAGTAGTATTCAAACaatgtgttttgttatttgCATGCAATAAAACAGTTTGCTGATCGAT

Function

symbol description
pink1 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within several processes, including dopaminergic neuron differentiation; nucleate erythrocyte development; and regulation of vascular endothelial growth factor signaling pathway. Located in cytosol and mitochondrion. Is expressed in several structures, including digestive system; gill; heart; nervous system; and spleen. Used to study Parkinson's disease and early-onset Parkinson's disease. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1).

NR:

description
serine/threonine-protein kinase PINK1, mitochondrial

GO:

id name namespace
GO:0051402 neuron apoptotic process biological_process
GO:0071542 dopaminergic neuron differentiation biological_process
GO:0060872 semicircular canal development biological_process
GO:1900746 regulation of vascular endothelial growth factor signaling pathway biological_process
GO:0048823 nucleate erythrocyte development biological_process
GO:0006468 protein phosphorylation biological_process
GO:2000377 regulation of reactive oxygen species metabolic process biological_process
GO:0005829 cytosol cellular_component
GO:0005739 mitochondrion cellular_component
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K05688 PINK1; PTEN induced putative kinase 1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043225105.1 True 2395 mRNA 0.52 9 17778474 17784124

Neighbor

gene id symbol gene type direction distance location
LOC122328974 agmat,LOC107714919,LOC102790280 coding downstream 554 17773405 ~ 17777920 (-)
tmed4 tmed4,LOC107594055,LOC107671834,LOC107715031,LOC107598625,LOC107697966,LOC107707037 coding downstream 340461 17433732 ~ 17438013 (-)
racgap1 racgap1,LOC107671897,LOC107594001,LOC107697971,LOC107756422,LOC107714933,LOC107599350 coding downstream 417090 17354147 ~ 17361384 (-)
bin2a LOC107671903,LOC107715035,LOC107594002,LOC107697868,LOC107598577,LOC107756358 coding downstream 427526 17344102 ~ 17350948 (-)
pou6f1 pou6f1,LOC107671889,LOC107715037,LOC107598516,LOC107756417,LOC107697973 coding downstream 447587 17316628 ~ 17330887 (-)
LOC122328575 LOC107714980,LOC107664226,LOC107563140,LOC107664227,LOC107714944 coding upstream 591 17784715 ~ 17786242 (-)
LOC122328417 LOC107563141,LOC107563138,LOC107664227,LOC107751839,LOC107599502,LOC107714980,LOC107664226,LOC107563140 coding upstream 3473 17787597 ~ 17788930 (-)
LOC122328416 LOC107599143,LOC107697854,LOC107751854,LOC107714945,LOC107563142,LOC107664148 coding upstream 4856 17788980 ~ 17796430 (-)
fam43b fam43b,LOC107563144,LOC107714947,LOC107664143,LOC107697855,LOC107577211 coding upstream 50719 17834843 ~ 17836972 (-)
vwa5b1 vwa5b1,LOC107706959,LOC107714920,LOC107664114,LOC107563127 coding upstream 94943 17879067 ~ 17914537 (-)
G158706 LOC107599375,LOC107715025,LOC107671876,LOC107594031,LOC104946192 non-coding downstream 29972 17746530 ~ 17748502 (-)
G158632 NA non-coding downstream 383052 17394021 ~ 17395422 (-)
G158628 NA non-coding downstream 391920 17383342 ~ 17386554 (-)
G158608 dazap2,LOC107715036,LOC107594003,LOC107671873,LOC107756418,LOC107598568 non-coding downstream 439555 17311328 ~ 17338919 (-)
G158605 NA non-coding downstream 486931 17289971 ~ 17291543 (-)
LOC122328377 NA non-coding upstream 15718 17799842 ~ 17844102 (-)
G158774 NA non-coding upstream 159801 17943925 ~ 17944160 (-)
G158887 NA non-coding upstream 215709 17999833 ~ 18001690 (-)
G158892 NA non-coding upstream 228002 18012126 ~ 18015877 (-)
G158882 NA non-coding upstream 257786 18041910 ~ 18043476 (-)
coq10a si:dkey-190g6.2,LOC107671896,LOC107715030,LOC107598614,LOC107697969,LOC102210977,LOC108425511,LOC102797363 other downstream 355957 17413703 ~ 17422517 (-)
G158609 NA other downstream 435089 17339267 ~ 17343385 (-)
slc48a1a slc48a1a,LOC107671836,LOC107598487,LOC107594008,LOC107756371,LOC107697869,LOC107757747 other downstream 594089 17176625 ~ 17184385 (-)
G158336 LOC107716221,LOC107570608,LOC107586536,LOC106567035 other downstream 1419769 16355369 ~ 16358705 (-)
tac3a LOC107708854,LOC107571761,LOC107681951,LOC107586540,LOC107695797 other downstream 1535079 16240810 ~ 16243395 (-)
march9 march9,LOC107593952,LOC107664138,LOC107714987,LOC107706970,LOC107599679,LOC107697857,LOC107088728,LOC108433385,LOC103130462,LOC105930772 other upstream 261802 18045926 ~ 18058739 (-)
hnrnpa1b hnrnpa1b,LOC107664187,LOC107714994,LOC107707002 other upstream 447519 18231643 ~ 18235536 (-)
hoxc1a LOC107598919,LOC107707004,LOC107697929,LOC107594049,LOC107664160,LOC107714959 other upstream 511922 18296046 ~ 18302575 (-)
hoxc6a hoxc6a,LOC107593966,LOC107664205,LOC107714999,LOC107706971,LOC107697939,LOC107598897 other upstream 558210 18342334 ~ 18350347 (-)
G159076 LOC107715021,LOC107664216,LOC107593990,LOC107598736,LOC107697953,LOC107707026 other upstream 963267 18747391 ~ 18754712 (-)

Expression


Co-expression Network