chrm2a (chrm2a,LOC107561244,LOC107658987,LOC107707993,LOC107568718,LOC107662193,LOC108427087)


Basic Information

Item Value
gene id chrm2a
gene name chrm2a,LOC107561244,LOC107658987,LOC107707993,LOC107568718,LOC107662193,LOC108427087
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NW_025047891.1
NCBI id JAEQBD010000236.1
chromosome length 1270053
location 967053 ~ 1037182 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043230810.1
ATATTGATGTAGCTTAGACGCCTGTAAAGCGAAGTGTGTTGATGATGTGAGAATGATGCTGTGAAGGGACCTCCTGCGTCTCCTCCCCTCCCTCCTGCTCTCCTGCTCCTCATTCCCACTCCTCATTTCGCGTTCACCCACGAGAAGAGATCCGAGCGTCCAGCATCATGTCCTCAGACGTCCAGCTGCGCGACCAAACGGACAGCAGCGACCCCGCGGGCGCCCGGAGCGACTGAGAGCAGGTGTCAGAAGTCATACGTCCTGCCCAAAGTGAACTGACCAGCTTTTGTCACCATGGATACAATAAACTTCACCTTCTGGAATGCCTCTGAGGGCAACGAGACCCTGGAGACGGTGGACGAGAGCCCGTACAAGACAGTGGAGGTGGTGTTCATTGTACTGGTGGCCGGCTCACTTAGCTTGGTGACTGTTATCGGGAACATCTTGGTCATGCTCTCCATCAAGGTAAACAGGAGCCTGCAGACTGTCAACAACTACTTCCTTTTCAGCCTGGCCTGTGCTGACCTCATCATTGGCCTTTGCTCTATGAACTTGTACACGGTCTACATTGTGATTGGATACTGGCCGCTCGGCCCGGTCGTGTGCGACTTGTGGTTGGCGCTGGACTACGTGGTCAGCAACGCCTCCGTCATGAACCTGCTGATCATCAGCTTCGACCGCTACTTTTGCGTCACCAAGCCGCTCAGCTACCCAGTGAAGAGGACCACCAAAATGGCAGGCATGATGATTGCTGCGGCATGGGTTTTGTCCTTCATCCTTTGGGCCCCGGCCATCCTGTTCTGGCAGTTCATCGTTGGCGGGCGCACTGTGCCAGAGAAGGAGTGCTACATTCAGTTCTTCTCCAACGCCGCGGTCACCTTCGGCACAGCCATTGCTGCTTTCTACCTGCCCGTCATCATCATGATGGTGCTCTACTGGCAGATATCTCGCGCTAGCAAGAGCCGAGTCAAGAAGGACAACCGCAAGCCGTCAGGCGGTAACATCGATGTAGCCTCGTCCAATCAGATCCGCGAAAACACAGCCAACAAACCAACCAACAACAACCTGACAGCTGACGAAACAGACCGAGGACAGACCCAGCTAACAGATGATGCCGCCAACCAACATGATGCCAAACTCCAGAACGGTAAAGCCCCATCCACGGCGAGCGGAGAAGCGGAGGCGGAAGATGCAGGACGAGGAAACTGCGTTCCCACTGAGGAGAAAGAGAGCTCCAATGACTCCACCTCTGGCAGCGGAGCTGTAACCAATCAAAAGGACGAGCCGGCTCCATCCAAAGCCAACGACAGCCAGGCTCCCACGAGGCACCGCGCCAAAGCTGGAGGCTCCAAACTGACGTGCATCAAGATCATCACCAAATCCCCAAAGGGCGACTGCTACGCGCCTTCAAACGCGACAGTGGAGATCGTCCCGGCCACCGAGAGGCAGAACCACgtggccaggaagatcgtgaaGATGACCAAGCAGCCGCCCAAGAAGAAAAAAGCACCGTCCTCTCGGGAAAAGAAGGTGACGCGCACCATCATGGCCATCCTGGTGGCCTTCGTGGCTACTTGGACGCCCTACAACGTGATGGTCCTCATCAACACCTTCTGCTCCAGCTGCATTCCCAACACCGTGTGGACCATCGGATATTGGCTCTGCTACATCAACAGCACCATCAACCCCGCCTGCTACGCCCTCTGCAACATCACCTTCAAAAAGACCTTCAAACACCTGCTGCTCTGCCAGTACAAGAACATACGCACGGCCCGATGagctgtagtgtgtgtgcatgcgttacactttacatgtgtgtgttctggtgaCAACGGCACAAAGGTACACGTGtggatgtgtttgtatgtgtggaAAGATCTGATgggttcatttgcaaaaacagataactatGTTTTCAACAATTTCcttaaatgtgaccctggaccacaaaacaaagtcgctggggtatatttatagcaatagcccaAAATACATTGTACGAGGCAAAtagtacatttttctttttatgccaaaaatcattagtacATTAAGTAAAAGTCATGTgccatgaagacattttgtcaatttcctgtaaatatatcaaaacttaattcttGATgggtaatatgcatttataagaacttcatttggacaactttaaaggcgatttgctcagtatttagaattttttgctccctcagattcatattagttgtatcttggccaaatactgtccttatatatatattcagctttcaggtaTAAATCTGTTAACAAACAATTAcccttatggctggttttgtggtccagggtcacaaatcacgttttttattgttatcatctTGTTTTACTGTGTataattttagttattattattattattcaatcgAATCAACCCAACTGTGGTTTGATTGATGTTAATTGGAATGCAGGACAATAAACAGTTATCTAAAAAAAGTTATCTGTTTCCACAAATGAACACTTCAATTACAAATGACAGATTGACCCATCAACACCCATCATATACAAAGTTTTAAGAATCTTTGTAAGTCCTTGTAGTTTGCCGAATTTGACACGGTCAGCTCCAAGTGCtccatttaaacacatttcaccATGTTTAAAATCACAGATTTCCCTAAAATGAGTGTAAAAACGTGCATCTGGGCAGATGTGtgattgcatttattgttttatatatatatata

Function

symbol description
chrm2a Enables G protein-coupled acetylcholine receptor activity. Acts upstream of or within cardiac conduction system development and negative regulation of heart rate. Predicted to be located in postsynaptic membrane. Predicted to be integral component of membrane. Predicted to be active in dendrite and synapse. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; digestive system; head; and neural tube. Human ortholog(s) of this gene implicated in several diseases, including Chagas disease; bipolar disorder; heroin dependence; major depressive disorder; and schizophrenia. Orthologous to human CHRM2 (cholinergic receptor muscarinic 2).

NR:

description
PREDICTED: muscarinic acetylcholine receptor M2

GO:

id name namespace
GO:0007213 G protein-coupled acetylcholine receptor signaling pathway biological_process
GO:0007268 chemical synaptic transmission biological_process
GO:0010459 negative regulation of heart rate biological_process
GO:0005887 integral component of plasma membrane cellular_component
GO:0016907 G protein-coupled acetylcholine receptor activity molecular_function

KEGG:

id description
K04130 CHRM2; muscarinic acetylcholine receptor M2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043230810.1 True 2705 mRNA 0.48 2 967053 1037182

Neighbor

gene id symbol gene type direction distance location
LOC122333207 NA coding upstream 34189 931241 ~ 932864 (+)
LOC122333262 NA coding upstream 107310 851301 ~ 859743 (+)
atp23 atp23,xrcc6bp1,LOC106576246,LOC106609469 coding upstream 119131 844355 ~ 847922 (+)
eps8a LOC107561250,LOC107568712,LOC107707945 coding upstream 131739 801545 ~ 835314 (+)
trnam-cau_120 NA coding upstream 167048 799934 ~ 800005 (+)
LOC122333216 NA coding downstream 46212 1083394 ~ 1086227 (+)
LOC122333217 LOC107707997 coding downstream 49590 1086772 ~ 1089265 (+)
slc38a4 slc38a4,LOC107658982,LOC107662190,LOC107707107,LOC107555871,LOC107590506,LOC108411501 coding downstream 77550 1114732 ~ 1139102 (+)
slc38a2 LOC107707990,LOC107658981,LOC107662192,LOC107590504 coding downstream 118282 1155464 ~ 1165727 (+)
scaf11 scaf11,LOC107707986,LOC107658980 coding downstream 129512 1166694 ~ 1176617 (+)
G178639 NA non-coding upstream 18146 946107 ~ 948907 (+)
G178633 NA non-coding upstream 43228 918789 ~ 923825 (+)
G178621 NA non-coding upstream 56458 845425 ~ 910595 (+)
G178627 NA non-coding upstream 98477 867454 ~ 868576 (+)
G178619 NA non-coding upstream 123078 842836 ~ 843975 (+)
G178664 NA non-coding downstream 105112 1142294 ~ 1142530 (+)
G178666 NA non-coding downstream 114094 1151276 ~ 1151551 (+)
G178670 NA non-coding downstream 143512 1180694 ~ 1182218 (+)
G178699 NA non-coding downstream 208990 1246172 ~ 1247077 (+)
G178593 NA other upstream 128500 836350 ~ 838553 (+)
crebl2 crebl2,LOC107658994,LOC107707978 other upstream 188688 775376 ~ 778365 (+)
LOC122333210 fam19a2,LOC107698008,LOC107662242,LOC107728758,LOC106576259 other upstream 428175 524311 ~ 538878 (+)
G178541 NA other upstream 510699 451126 ~ 456354 (+)
G178503 NA other upstream 700325 264517 ~ 266728 (+)

Expression


Co-expression Network