CI01000004_03238528_03240932 (GFI1AA, GFI1)


Basic Information

Item Value
gene id CI01000004_03238528_03240932
gene name GFI1AA, GFI1
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000004
NCBI id null
chromosome length 17451736
location 3238358 ~ 3241491 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000004_03238528_03240932.mRNA
AAATATTGTGCATGACGCGATGGATATTCAATTCTAAACCGTATAGACTATTAATAGCTATTATCTAATTTTCTTCCTTATTATTAGGGAAATAAATCTGCAGTTTTAAATGCTATTTGAAACTAATTGTTTATCCCCTGTGCTTGGAATTTGATGTTCTTCAAGTCTCGACATCAGGTTATTAACGACCGCAACAAAACCAATTAGTTATTGGCAATAATACCCTGGGCCCCATTTGCAGTCTGTTACTTGGAAGTGACGTGATGTTGATATATCATGCGGACAGAGGATCAGTTTACTAAATAAGGCTTTGAGATCAAGTTGCCAAGAGGGAGCCTATAACAAAGTGCGCCGTGCAGTTCCTCGACTTCAAATCGCTTTTGCTTTATTTGGGAGGTTTTGATTGCAAAAGGCTGCGGGATAGAGATTTGACAGACCTGCTGCTGTGTATATCAGGTGCATTTTTTCACACCGGCGCTGCTCTTGAAATCCACTTTTCAGGCAGGATTGGAGAGCCGTGAGTGATTGATGACCCTGAACCTGATAACGGAGAGTAAACATGCCGAGGTCATTTTTGGTGAAGAGCAAACGGGCGCACAGTTATCATCAACCCCGTTACCTGGACGACAACTGCATCCCAACTGAGAAACTTCTCACGTGCCAAGAAAGTCAAATGGGGCAAATCCCCGAGAGCCCGGCGGATGTGGGAAATCATTCCCCTAAAACCAGCATGGTGTGCACGGCGGATCATTCCTCCCAACAGTCCCCGCTGAGCTGCGAGGGCAGTGTGTGTGACCGCTCATCCGACTATGACGACTTCTGGAGACCCCTGTCCTCAGGAACCTCTCCAGATCTGGATAAATCGCCTTCTCCAGACGACTCTCAGCCTTTCGACTTGTCTTTTCGTCCGTACGTTTGGGCCCATTCAACATCCGAGCTCAGACACCTCATTCAATCTTGCAACCGTGTTTCTGCGGATTCAGAGACATCAATGGGGGTGTATGATGCCATGGACAGAAGGCCGGGTGCCCATCTCCTCATTGAACCAGCACAATCCGGGCGATTTTACCAGGACTATGGCTCCCTGAACACTAACCTGTTGGATAGTAGAGGCTTCTATGCAGACTTCAAGATGTCAACTAAAGTAGCAGAGATTGATTCGGAGTCTGATATTATGTCCACGCGACTTCAGCTAAGCGGCTCGTACAAATGCGTAAAATGCACTAAGGTGTTTTCAACCCCTCATGGGTTAGAAGTTCACGTGCGGCGGTCTCACAGTGGCACGAGGCCCTTCGCGTGCGAAATCTGTGGAAAAACGTTCGGCCACTCGGTCAGCTTGGAGCAACATAAAGCTGTCCATTCACAAGAAAGAGTCTTCAGCTGCAAAATCTGCGACAAAAGTTTCAAGAGGTCGTCCACTTTGTCCACGCACCTCCTCATCCACTCTGATACCAGACCATATCCCTGTCAGTACTGCGGCAAACGATTCCATCAGAAATCAGATATGAAGAAACACACGTTCATTCATACAGGTGAAAAGCCACACAAGTGTCAGGTGTGTGGAAAAGCCTTTAGTCAGAGTTCAAACCTCATCACACACAGCAGAAAACACACAGGATTCAAGCCTTTCGGATGCGAACTGTGTGGCAAAGGATTTCAGCGCAAAGTAGATCTGAGGAGACACAAAGAAACGCAGCATGGACTAAAATAACGCATTTTTTTTTCTTACATATGTTTGTTTGCACATGCATGTAACACTATTTAGAATTAGAAGGTAATATTGTGTGGTTTTATGAATTAAGAAAATAACGCATTTATTTGATTTCCGATACACAGTATTTTATAACAAGCTGGGATATTTTGTTCTAAATATTTAATAAA

Function

symbol description
gfi1aa Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within primitive erythrocyte differentiation. Predicted to be active in nucleoplasm. Is expressed in several structures, including artery; hematopoietic cell; intermediate cell mass of mesoderm; mesoderm; and sensory system. Human ortholog(s) of this gene implicated in acute myeloid leukemia and severe congenital neutropenia 2. Orthologous to human GFI1 (growth factor independent 1 transcriptional repressor).
gfi1 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to lipopolysaccharide; negative regulation of cellular biosynthetic process; and regulation of signal transduction. Located in nuclear body and nuclear matrix. Part of transcription repressor complex. Implicated in acute myeloid leukemia and severe congenital neutropenia 2. Biomarker of leukemia and myelodysplastic syndrome.

GO:

id name namespace
GO:0050767 regulation of neurogenesis biological_process

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000004_03238528_03240932.mRNA True 1881 mRNA 0.45 6 3238358 3241491

Neighbor

gene id symbol gene type direction distance location
CI01000004_03214098_03222707 GLMNA, GLMN coding downstream 15651 3214098 ~ 3222707 (-)
CI01000004_03204599_03205569 TCEANC2 coding downstream 32290 3204572 ~ 3206068 (-)
CI01000004_03187077_03196194 MRPL37 coding downstream 42160 3187077 ~ 3196198 (-)
CI01000004_03133701_03141953 ACOT11, ACOT11A coding downstream 96379 3133674 ~ 3141979 (-)
CI01000004_03106070_03109051 NA coding downstream 129307 3106042 ~ 3109051 (-)
CI01000004_03244252_03265862 EVI5 coding upstream 2412 3243903 ~ 3266047 (-)
CI01000004_03277921_03285364 FAM69AA, FAM69A coding upstream 36250 3277741 ~ 3285364 (-)
CI01000004_03433963_03436906 GADD45A, GADD45AA coding upstream 192341 3433832 ~ 3436906 (-)
CI01000004_03475454_03478135 NA coding upstream 233403 3474894 ~ 3479485 (-)
CI01000004_03505898_03508656 NSUN4 coding upstream 264307 3505798 ~ 3508770 (-)
G26820 NA non-coding downstream 23156 3214890 ~ 3215202 (-)
G26754 NA non-coding downstream 59000 3172410 ~ 3179358 (-)
G26744 NA non-coding downstream 105593 3132556 ~ 3132765 (-)
G26752 NA non-coding downstream 116098 3119950 ~ 3122260 (-)
G26751 NA non-coding downstream 121077 3116786 ~ 3117281 (-)
G26788 NA non-coding upstream 26192 3267683 ~ 3275721 (-)
G26810 NA non-coding upstream 59308 3300799 ~ 3306425 (-)
G26812 NA non-coding upstream 89254 3330745 ~ 3332243 (-)
G26811 NA non-coding upstream 101323 3342814 ~ 3355165 (-)
G26803 NA non-coding upstream 104509 3346000 ~ 3351924 (-)
CI01000004_01773383_01774888 INSL5B other downstream 1463417 1772928 ~ 1774942 (-)
G27746 NA other upstream 1936736 5178227 ~ 5203724 (-)
CI01000004_05617072_05627369 NA other upstream 2378892 5616644 ~ 5628289 (-)
CI01000004_06539836_06541252 NA other upstream 3293336 6538904 ~ 6541252 (-)
G29388 NA other upstream 3389802 6631293 ~ 6631907 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location