apex1 (apex1,LOC107658891,LOC107725930,LOC107583973,LOC107656416)


Basic Information

Item Value
gene id apex1
gene name apex1,LOC107658891,LOC107725930,LOC107583973,LOC107656416
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056702.1
NCBI id CM032071.1
chromosome length 29200999
location 1618977 ~ 1621881 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043236314.1
ATGCACATTGCAGAAAGCTTCGGCTTCCCGTCCTTGCAGAGCAGTTTATAGTTCTGCGCAGATTGAGGTTTTATTATAAAGTCAACTAACGATTAAAGTGTTAGCATACTGCAGGCACATGCATTTTGGTTTATGCAGTTCGCGTATTTTATGTGTCCGTGTGTGGGCTGTCAGTTTCTTACGTGTTTGTGGTCTTAAAACAACTGTAAGCATGCCTAAAAGAGCCAAGAAGAATGAGGAAGCTGTCGATGGGGAGACTGGCAATGGAGCTGAACctgcaaagaaagagaaaaagggaaAGGAGCCAGAGGCCCCAATTCTGTATGAAGATCCTCCAGATAAGATGACCAGTAAGGATGGCCGTGCATCCAACATGAAGATCACGTCCTGGAATGTGGACGGTCTGCGCGCGTGGGTCAAAAAGAACGGACTTGATTGGGTGCGTAAGGAGGATCCAGATGTGCTGTGTCTGCAGGAGACTAAGTGCGCTGAGAAAGCCCTGCCGTCTCAGATCACTGAAATGCCTGAGTATCCACACAAGTACTGGGCTGGATCAGAGGATAAGGAGGGTTACAGCGGAGTCGCCATGCTCTGCAAGACTGAACCACTCAGTGTCACCTATGGTATTGGTAAAGAAGAGCATGATAAAGAAGGTCGGGTGATCACTGCTGAGTTTCCGTCTTTCTTCCTGGTCACGGCGTATGTGCCTAATGCAAGTCGCGGTTTGGTGCGCCTCGACTACCGTAAGACCTGGGATGTGGATTTCCGGGCCTACCTGAGTGGCTTGGATCAGCGAAAGCCCCTGGTGCTGTGTGGAGATCTGAATGTGGCCCACCAAGAGATTGATCTAAAAAACCCCAAGGGTAACCGCAAGAACGCAGGCTTCACCCCCGAGGAACGTGAGGGCTTCACCAAACTTCTGGAGGCCGGTTTTACCGACAGTTTTCGGGAGCTATATCCGGATCAAGCCTATGCCTACACCTTCTGGACCTACATGATGAATGCCCGAGGCAAAAACGTCGGCTGGCGTTTGGACTACTTTGTGCTCTCGTCTGCCTTGCTCCCAGGTCTGTGTGACAGCAAGATCCGAAACACAGCCATGGGAAGTGACCACTGTCCTATTACCTTGTATTTGGCAGTGTAGAGCAGGCTTCTCAGGGCCCTACGTTTTTCAGTTCCGTATGCATCTGCATAGACATAAGAATCTAGTCCTGTTAGTTCTAGAATAGTATTTCAGTTCTAAAAACCAAATACAAACCCACATATAGGAATATGTGTCATGCAGACACGCATTGAAAAGAGTCTTGGATAAAGTGTTTTGCTGTTTTGGATAATTCTACTGTTAATGGTCATCTGAAAGTAGATTTTGACACtaaaatctcacaaaaaaaacaactttatatttgcaatgtttaaaaaaaaaaaacctcagacTGTTATCTAAATGATAAACCCTGCCAGACTACTGTAATAATTGTTTCAGTGTTGATTAtagcaaaacattttgaagcTTGTAAAATACATTGACCTGCAAAGATATATGATGTGTCTGATTAGTATGAAGTTCTTTGGATTTTGTCTTTGGTGCTATTTTAACCTTTGGATTCTTCTTTACTCTCGACTTAGTGAAGTTAGTGGTGGTTAAATGTTACATGTGCCACTTTCAAAAGACCAGTGTTTTTccttatgtacttttttttcccatagtGTGTCTGTATAGCCATTTTTCAGGTTTTCAAATAAagtagtttataaaaaaaaaaaaaaa
>XM_043236315.1
TTTATAGGGAAACATGCGCCTCATGCACATTGCAGAAAGCTTCGGCTTCCCGTCCTTGCAGAGCAGTTTATAGTTCTGCGCAGATTGAGGTTTTATTATAAAGTCAACTAACGATTAAAGTGTTAGGTGTCCGTGTGTGGGCTGTCAGTTTCTTACGTGTTTGTGGTCTTAAAACAACTGTAAGCATGCCTAAAAGAGCCAAGAAGAATGAGGAAGCTGTCGATGGGGAGACTGGCAATGGAGCTGAACctgcaaagaaagagaaaaagggaaAGGAGCCAGAGGCCCCAATTCTGTATGAAGATCCTCCAGATAAGATGACCAGTAAGGATGGCCGTGCATCCAACATGAAGATCACGTCCTGGAATGTGGACGGTCTGCGCGCGTGGGTCAAAAAGAACGGACTTGATTGGGTGCGTAAGGAGGATCCAGATGTGCTGTGTCTGCAGGAGACTAAGTGCGCTGAGAAAGCCCTGCCGTCTCAGATCACTGAAATGCCTGAGTATCCACACAAGTACTGGGCTGGATCAGAGGATAAGGAGGGTTACAGCGGAGTCGCCATGCTCTGCAAGACTGAACCACTCAGTGTCACCTATGGTATTGGTAAAGAAGAGCATGATAAAGAAGGTCGGGTGATCACTGCTGAGTTTCCGTCTTTCTTCCTGGTCACGGCGTATGTGCCTAATGCAAGTCGCGGTTTGGTGCGCCTCGACTACCGTAAGACCTGGGATGTGGATTTCCGGGCCTACCTGAGTGGCTTGGATCAGCGAAAGCCCCTGGTGCTGTGTGGAGATCTGAATGTGGCCCACCAAGAGATTGATCTAAAAAACCCCAAGGGTAACCGCAAGAACGCAGGCTTCACCCCCGAGGAACGTGAGGGCTTCACCAAACTTCTGGAGGCCGGTTTTACCGACAGTTTTCGGGAGCTATATCCGGATCAAGCCTATGCCTACACCTTCTGGACCTACATGATGAATGCCCGAGGCAAAAACGTCGGCTGGCGTTTGGACTACTTTGTGCTCTCGTCTGCCTTGCTCCCAGGTCTGTGTGACAGCAAGATCCGAAACACAGCCATGGGAAGTGACCACTGTCCTATTACCTTGTATTTGGCAGTGTAGAGCAGGCTTCTCAGGGCCCTACGTTTTTCAGTTCCGTATGCATCTGCATAGACATAAGAATCTAGTCCTGTTAGTTCTAGAATAGTATTTCAGTTCTAAAAACCAAATACAAACCCACATATAGGAATATGTGTCATGCAGACACGCATTGAAAAGAGTCTTGGATAAAGTGTTTTGCTGTTTTGGATAATTCTACTGTTAATGGTCATCTGAAAGTAGATTTTGACACtaaaatctcacaaaaaaaacaactttatatttgcaatgtttaaaaaaaaaaaacctcagacTGTTATCTAAATGATAAACCCTGCCAGACTACTGTAATAATTGTTTCAGTGTTGATTAtagcaaaacattttgaagcTTGTAAAATACATTGACCTGCAAAGATATATGATGTGTCTGATTAGTATGAAGTTCTTTGGATTTTGTCTTTGGTGCTATTTTAACCTTTGGATTCTTCTTTACTCTCGACTTAGTGAAGTTAGTGGTGGTTAAATGTTACATGTGCCACTTTCAAAAGACCAGTGTTTTTccttatgtacttttttttcccatagtGTGTCTGTATAGCCATTTTTCAGGTTTTCAAATAAagtagtttataaaaaaaaaaaaaaa

Function

symbol description
apex1 Predicted to enable DNA-(apurinic or apyrimidinic site) endonuclease activity; double-stranded DNA 3'-5' exodeoxyribonuclease activity; and phosphodiesterase I activity. Acts upstream of or within several processes, including heart contraction; heart looping; and negative regulation of apoptotic process. Predicted to be located in endoplasmic reticulum; mitochondrion; and nuclear lumen. Predicted to be active in nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in breast cancer; female reproductive organ cancer (multiple); spina bifida; and urinary bladder cancer. Orthologous to human APEX1 (apurinic/apyrimidinic endodeoxyribonuclease 1).

NR:

description
PREDICTED: DNA-(apurinic or apyrimidinic site) lyase

GO:

id name namespace
GO:0010628 positive regulation of gene expression biological_process
GO:0080111 DNA demethylation biological_process
GO:0043066 negative regulation of apoptotic process biological_process
GO:0001947 heart looping biological_process
GO:0060047 heart contraction biological_process
GO:0006281 DNA repair biological_process
GO:0005783 endoplasmic reticulum cellular_component
GO:0016607 nuclear speck cellular_component
GO:0005730 nucleolus cellular_component
GO:0005739 mitochondrion cellular_component
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity molecular_function
GO:0046872 metal ion binding molecular_function
GO:0016491 oxidoreductase activity molecular_function
GO:0003677 DNA binding molecular_function
GO:0003723 RNA binding molecular_function

KEGG:

id description
K01142 E3.1.11.2, xthA; exodeoxyribonuclease III

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043236314.1 True 1768 mRNA 0.44 6 1618977 1621859
XM_043236315.1 False 1742 mRNA 0.44 5 1618977 1621881

Neighbor

gene id symbol gene type direction distance location
LOC122342781 selenoo,LOC107579553,LOC107711487,LOC107725908,LOC105900684 coding downstream 15264 1601675 ~ 1603713 (-)
LOC122342889 NA coding downstream 25608 1591389 ~ 1593369 (-)
LOC122342888 LOC107584032,LOC107579834,LOC107656234,LOC107711464,LOC107725908 coding downstream 27672 1588279 ~ 1591305 (-)
ano2b LOC107658923,LOC107726040,LOC107583957,LOC107579307,LOC107656385,LOC107711491 coding downstream 56430 1530792 ~ 1562547 (-)
gnsa gns,gnsa,LOC107658926,LOC107656403 coding downstream 145752 1468197 ~ 1473225 (-)
si:ch211-214j24.10 si:ch211-214j24.10,LOC107725935,LOC107711484,LOC107583983,LOC107656420,LOC107579683,LOC107658903 coding upstream 3414 1625295 ~ 1628655 (-)
si:ch211-214j24.14 LOC107658910,LOC107579438,LOC107725940 coding upstream 33155 1655036 ~ 1658265 (-)
LOC122343486 LOC107583996,LOC107725944,LOC107658917,LOC107579452,LOC107656399,LOC107579492 coding upstream 44764 1666645 ~ 1670146 (-)
LOC122343487 LOC107583996,LOC107658917,LOC107725944,LOC107656399,LOC107579452,LOC107579492 coding upstream 53321 1675202 ~ 1678612 (-)
rad51ap1 LOC107658893,LOC107579575 coding upstream 59068 1680949 ~ 1683573 (-)
G25098 NA non-coding downstream 41252 1577201 ~ 1577725 (-)
G25028 NA non-coding downstream 42261 1576061 ~ 1576716 (-)
G25027 NA non-coding downstream 43558 1570293 ~ 1575419 (-)
G25019 tbc1d30,LOC107725910 non-coding downstream 138084 1478609 ~ 1480893 (-)
G25001 LOC107726026,LOC107658929,LOC107656386 non-coding downstream 198715 1418186 ~ 1420262 (-)
G25124 NA non-coding upstream 38724 1660605 ~ 1661388 (-)
G25125 LOC107583967,LOC107658918,LOC107725927,LOC107656410,LOC107711479 non-coding upstream 40464 1662345 ~ 1662607 (-)
G25126 cecr1b,LOC107656410,LOC107711479,LOC107583967,LOC107725927,LOC107581132 non-coding upstream 41192 1663073 ~ 1663900 (-)
G25127 NA non-coding upstream 43957 1665838 ~ 1666137 (-)
G25133 NA non-coding upstream 66477 1688358 ~ 1688894 (-)
zgc:113263 LOC107658878,LOC107583959,LOC107725918,LOC107656382,LOC107711463 other downstream 679 1609360 ~ 1618298 (-)
selenoo2 selenoo,si:dkey-14d8.2,LOC107579362,LOC107711485 other downstream 14287 1594284 ~ 1604690 (-)
LOC122342802 LOC107711465,LOC107656235 other downstream 32788 1580480 ~ 1586189 (-)
ptprz1b ptprz1,ptprz1b,LOC107725913,LOC107656236,LOC107658935,LOC107581028 other downstream 295580 1289314 ~ 1323397 (-)
G24875 NA other downstream 548881 1069160 ~ 1070096 (-)
ccdc167 ccdc167 other upstream 31710 1653591 ~ 1654826 (-)
rsph9 rsph9,LOC107658900,LOC107583979,LOC107579672,LOC107710090,LOC107656226 other upstream 276522 1898403 ~ 1902663 (-)
cald1a cald1a,LOC107583995,LOC107725991,LOC107658884,LOC107656362,LOC107710121 other upstream 421072 2042953 ~ 2088579 (-)
tnni4a zgc:101560,LOC107725970,LOC107584059,LOC107658770,LOC107656258,LOC107581287 other upstream 469470 2091351 ~ 2097801 (-)
dock4b dock4b,LOC107656358,LOC108425388 other upstream 677754 2299635 ~ 2375716 (-)

Expression


Co-expression Network