six1b (six1b,six1,LOC107589069,LOC107563694,LOC107697302,LOC108434988)


Basic Information

Item Value
gene id six1b
gene name six1b,six1,LOC107589069,LOC107563694,LOC107697302,LOC108434988
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056702.1
NCBI id CM032071.1
chromosome length 29200999
location 16937799 ~ 16939687 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043236321.1
GCTGCCGGGGATAGGGCAGCCGGAGAGCCAATCAGCAGTCGCGCAGTGCTCTTTTAGCGCGACATGAGTCGATAGTGAGCAAACTGTCTTCAACAAACACCCAAAACTTCACGGCGCGCGCAGAGGACATCTCCAACCCCAAAAAATCCCGTCAGGCGACCTAATCGCTCTCGTTAAACGAAGGCGAACGGAGGTGTCTCCCGTTCCGCTTCCTTCACAAGCATCTAGAGGAGAGCGGTCTGGTAGCGGGAGTCAGACGTCATGTCAATGTTGCCTTCCTTCGGGTTTACTCAGGAGCAAGTcgcgtgcgtgtgtgaggtGCTGCAGCAAGGGGGGAACCTCGAGCGTCTCGGCCGTTTTCTGTGGTCTCTTCCGGCCTGCGACCATCTCCACAAGAACGAGAGCGTCCTCAAAGCCAAGGCCGTCGTCGCCTTCCACCGTGGAAACTTCAGGGAACTTTATAAGATACTAGAGAGTCACCAGTTCTCTCCGCACAACCACCCGAAGCTGCAGCAGCTGTGGCTTAAGGCCCATTACATCGAGGCTGAAAAACTGAGGGGGCGACCGCTGGGAGCGGTGGGGAAATATCGGGTGCGGAGGAAATTTCCTCTGCCGCGCACAATATGGGACGGCGAGGAGACCAGCTACTGTTTTAAGGAGAAATCCCGCGGTGTGCTGCGGGAGTGGTACACGCACAACCCCTATCCGTCTCCGCGGGAAAAGAGGGAGCTGGCCGAGGCCACGGGGCTGACCACCACACAAGTGAGCAACTGGTTTAAAAACAGAAGGCAGAGGGATCGCGCGGCGGAGGCGAAAGAAAGAGAGAACAGCGAGAACAGCAACACCGGCGCTAACAAACAGAACCAGCTGTCACCGCTGGACGGCGGGAAGTCCCTGATGTCGAGCTCGGAGGACGAATTCTCGCCCCCGCAGAGTCCTGACCAGAACTCCGTGCTCCTGCTCCAGGGTAACATGAGCCACCCCGGCGCGTCCGCGTACTCCATGACCGGCCTCGGCGCCGCTCAGTCGGTGCACGGCATGCAAGGACACCCGCATCAGCTTCAGGATTCTTTACTGGGACCTTTAACTTCAAGCCTGGTGGACCTCGGTTCTTAAGCGATCGCGActgagcttttatttattttattttttgtttattttgtaccAAATATAGACTGAGATCTGCCACttttactgtacatatatataaggGGGGGGGGAAACAGAACAGTATAAATCTTAAGTAAAACTCCTTCATTTTTCTCTGGTTTTCAGAGAAATACTCAGTGGTACGCTTTTACCGTGGTAGACTATTACGGACTGACATTTGCCAAGTCGTTAAACTGGTCAGAGGACGAACCAAAAGCAGTTAATAAAGCGATTCTTTTCTTCAAACTAATAA

Function

symbol description
six1b Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including muscle organ development; nervous system development; and regulation of skeletal muscle cell proliferation. Predicted to be located in cytoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including ectoderm; musculature system; nervous system; pharyngeal arch; and trunk. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Orthologous to human SIX1 (SIX homeobox 1).
six1 Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II and protein localization to nucleus. Located in nucleolus and nucleoplasm. Implicated in autosomal dominant nonsyndromic deafness 23; branchiootorenal syndrome; and nephroblastoma. Biomarker of breast cancer; hepatocellular carcinoma; nephroblastoma; neurilemmoma; and ovarian carcinoma.

NR:

description
homeobox protein six1b

GO:

id name namespace
GO:0051146 striated muscle cell differentiation biological_process
GO:0043282 pharyngeal muscle development biological_process
GO:0006915 apoptotic process biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0002074 extraocular skeletal muscle development biological_process
GO:0048839 inner ear development biological_process
GO:0021984 adenohypophysis development biological_process
GO:0048935 peripheral nervous system neuron development biological_process
GO:0005634 nucleus cellular_component
GO:0005737 cytoplasm cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K15614 SIX1; homeobox protein SIX1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043236321.1 True 1402 mRNA 0.54 2 16937799 16939687

Neighbor

gene id symbol gene type direction distance location
six4b six4b,LOC107743978,LOC107589068,LOC107563693,LOC107697301,LOC107701468,LOC107718441 coding upstream 5593 16925017 ~ 16932206 (+)
rhoj rhoj,LOC107697308,LOC107743974,LOC107701469,LOC107707080,LOC108257930 coding upstream 99375 16822113 ~ 16838424 (+)
chrna2b chrna2b,LOC107697311,LOC107589091,LOC107723144,LOC107746381,LOC107563692,LOC107701496,LOC108434998 coding upstream 227643 16701043 ~ 16710156 (+)
LOC122342226 NA coding upstream 320581 16615345 ~ 16617218 (+)
ptprb LOC107709971,LOC107685369,LOC107738449,LOC107575178,LOC107562139 coding upstream 480502 16436391 ~ 16457297 (+)
rtn1b rtn1b,LOC107560379,LOC107697289,LOC107701456,LOC107718426,LOC107743986,LOC107589072,LOC108434986,LOC108257846 coding downstream 60218 16999905 ~ 17026338 (+)
rd3l rd3l,LOC107697292,LOC107560380,LOC107743985 coding downstream 94234 17033921 ~ 17037157 (+)
ppp1r13bb LOC107560381,LOC107718410,LOC107755206 coding downstream 101170 17040857 ~ 17083120 (+)
brf1b brf1b,LOC107718407,LOC107683968,LOC107701485,LOC107755207,LOC107560373 coding downstream 182746 17122433 ~ 17176497 (+)
nudt14 nudt14,LOC107755236,LOC107718404,LOC107701483,LOC107683965 coding downstream 326770 17266457 ~ 17293636 (+)
LOC122342883 NA non-coding upstream 26457 16897515 ~ 16911342 (+)
G29026 NA non-coding upstream 185210 16748718 ~ 16752589 (+)
LOC122343214 LOC107589090,LOC107723504,LOC107697312,LOC107563691,LOC107746370,LOC107701470 non-coding upstream 237581 16698521 ~ 16700218 (+)
G29011 NA non-coding upstream 327795 16609724 ~ 16610004 (+)
G28991 NA non-coding upstream 397639 16519411 ~ 16540160 (+)
G29078 NA non-coding downstream 1329 16941016 ~ 16941310 (+)
G29086 NA non-coding downstream 97586 17037273 ~ 17038220 (+)
G29089 NA non-coding downstream 107184 17046871 ~ 17085857 (+)
LOC122342667 NA non-coding downstream 150852 17090539 ~ 17119106 (+)
G29178 NA non-coding downstream 279455 17219142 ~ 17219514 (+)
G28982 NA other upstream 463418 16473898 ~ 16474381 (+)
G28899 NA other upstream 952073 15985219 ~ 15985726 (+)
G28891 NA other upstream 1095944 15841372 ~ 15841855 (+)
cdkn1d LOC107699204,LOC107719868,LOC107562144,LOC107601015,LOC107758204,LOC107687563 other upstream 1282521 15565499 ~ 15655278 (+)
G28806 LOC107744205,LOC107601002,LOC107687568,LOC107699198 other upstream 1382117 15439334 ~ 15555682 (+)
atp5mj NA other downstream 98732 17038419 ~ 17040830 (+)
G29526 NA other downstream 1360728 18300415 ~ 18301189 (+)
G29545 NA other downstream 1496773 18436460 ~ 18461317 (+)
G29642 NA other downstream 1943492 18883179 ~ 18886402 (+)
G29814 LOC107660256 other downstream 2350533 19290220 ~ 19342911 (+)

Expression


Co-expression Network