esr2a (esr2,LOC107718402,LOC107701482,LOC107755240,LOC107683963)



Basic Information


Item Value
gene id esr2a
gene name esr2,LOC107718402,LOC107701482,LOC107755240,LOC107683963
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056702.1
NCBI id CM032071.1
chromosome length 29200999
location 17397135 ~ 17410852 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043237874.1
GACGGACGGAGCAGAGCACACTTTAACATGCATCCTGACAGCTCATCAAAACACTGGCCATTCTCCCATTACATAGGCTGGAACGGGGATCAAATCaagcaataaaatgttattttgggaTTCTTGCCGACTCAGAAACCAAGCCTTACAGTGGACCATCTGTTGATCAACTAAACATCGATTGCAACAGGTGCTTGTGCTCGGTGCCTGGTATGTTTTGGCCAGTTGCCTGTCTGTGCTAAAACAAGGGTTCAAAAGTCCTCGGCTGACTCACCGTTGGCAGTCCAGAGAGACAGTGTGGCTAACTGCCTCTCTCGCAAAGTACAGTCTACAACACTGTGTAGGCTGCATCACGTTTCAGTATCGATGACTGAGGAGTGCAACATGACTCGCATCAATAGCTCCCTGTTGATGATAAGACAGCACTGAACCCGTCCGCCTTCGCTATGTCCGAGTATCCCGAAGGAGACAGTTGTCTACTTCAGCTGCAGGAAGTGGACTCCAACAGGGTGGGAGGTCACGTCCTCTCTCCTGCCTTTAACTCTTCCTCTCCATCTCTGTCGGTGGAGAGCCACCCCATCTGCATCCCATCACCCTACACAGACCTCAGCCATGACTTCTCCACCCTGCCCTTCTACAGTCCTGCTCTGCTGGGGTACGGCGCGTCGCCTCTCTCCGACTGCCCATCTGTGAGGCAGTCGCTAAGCCCCTCCCTCTTTTGGCCACCTCATAGCCATGTTTCTTCGATTGCGTTGCATCAGCAACAGAATCGACTGCAACAAAACCACCCAGCTGGTGGGACCTGGGCAGATCTTACACCACATGATCACAGCGAAGAGGAATACTGCAAACCGCTGGCGAAGAGGGTAGGAGATGCAGAGGAGAGTTCTACTTCTTTGAGAGGTAAAGCTGACATGCACTACTGCGCCGTCTGTAGCGATTACGCCTCCGGGTATCATTATGGCGTGTGGTCGTGTGAAGGATGCAAAGCCTTCTTCAAGAGAAGTATACAAGGACACAATGACTACATCTGCCCCGCCACCAACCAGTGCACCATCGACAAGAACCGCCGCAAAAGCTGCCAGGCCTGCCGTCTGCGAAAATGTTATGAAGTTGGAATGATGAAATGCGGGTTACGGCGAGATCGTGGTAGCTACCAACAAAGAGGAGGACAGCAGAAACGGCTGGCACGATTCTCTAGCAGGATGAGAACATGTGGCCCGAGATCTCAAGAAATCAAAAGTGTCCCACGACCCCTCGGTGGAAATAAGGTGCTTAATATAGCCTTGAGCCCCGAGGAACTAATTGCTCGAATCATGGATGCAGAGCCACCCGAGATTTACCTCATGAAAGACATGAAGAAGCCATTCACTGAGGCCAACGTCATGATGTCGCTGACCAACCTGGCCGACAAAGAGCTTGTTCACATGATCAGCTGGGCCAAGAAGATCCCAGGTTTTGTGGAGCTCAGTCTTTTTGACCAGGTCCATTTGTTGGAGTGCTGCTGGTTGGAGGTGCTGATGCTGGGACTGATGTGGCGGTCCGTTAATCACCCTGGAAAGCTCATTTTCTCCCCAGACCTCAGTCTCAGCAGGGACGAAGGCAGCTGTGTGCAGGGGTTTGTGGAGATCTTTGATATGCTGCTGGCAGCCACATCCAGGTTCAGAGAACTGAAGTTACAGAGAGAGGAGTATGTGTGTCTCAAAGCCATGATCCTGCTCAACTCCAACATGTGCCTGAGTTCGTCTGAGGGAGGAGAGGAGCTGCAGAGCCGGTCGAAGCTGCTGTGTCTGCTGGACTCGGTGACGGATGCTCTGGTGTGGGCCATCTCCAAGACGGGCCTGAGCTTCCAGCAGCGCTCCACCAGACTGGCTCATCTGCTCATGCTGCTCTCCCACATAAGGCACCTCAGTAACAAAGGCATGGACCACCTCCACTGcatgaagatgaagaagatgGTTCCTCTGTATGACCTGCTTCTGGAGATGCTGGATGCTCATATCATGCACAGCTCCCGTCTGTCTCACTCCGGCCCTCGAGTGGCTCCTGCTCCTAAAGAGAGCAAAGTCGCTCAGGAGGCCTTCGCCTGCACTTCTCAGCATGGAGAGACCTTAGGAGCCTCAACCATTTCTGTGCTGAGGAATGATCTATAGTTTTGGGAGAATGGACAACAAAAACAGCCGCGCAGAAAAAGTGGAATACAATTTCTCaagctaaaaaacattttctttttaaaaaatttggcGTTTGCTGTGaaatcctctttttctttttttaacagaacTCATTTTGAACACAGTTGTTTTGTTGTATGTAGCCGTGAACACGCAACACAAAGAAAAGTCCTTCACTTTTTACAAAACCTTATTAATTGCCGGTGGTTTAAAAACTGGTTACCATTTGCTTTTTTGAAATGTAACATGTAACACATATCTGAAATCTGCACCACAATCGAATGTACACTTTCTATTTCTACGCTTATCATTTCCTCCTCTTTCTAAAAAGTACATTTGCAACTCTTGCTTTTTGTGAAGGCCAAAAGAAAATCAGCTGCAGCAACTGCTGTAGATAGAGCGACTATTGAAGACGCTGTCAGAACAAACAGATTCGATTCCTTCACTTTCAAAACGACAATATGAGCAGTCAGTGCTGAAGATGAGAGAGGTTTGTATGCAGTGGGAGCAGAGACCAAAGGCTCAGAAGAACTGAATCaagccttttttttctgtcaggaCTTACATTAGTAGGGCCAAATTCAGGACAGCTGGATGGATGTTATGTTTGCATCTATTACTTTTCACAAAACAGAAGCTTGTTCATCCTGCTCTCTACCCAGTAAACCCTTTAACACCATAACAGCCTTGTACaaagcatttatacattttctaaagacaGCTCAATCGATTGCTACTATTCCACTGTGAAAATCTGTTTGTAAGATGCACCATATGTACCAAAAAAGTACTTGTGATATTGCACTTTAATATTTCTCTGAACTATCTGAAGCCCTATCTTGagaattatatatacagtagtcaacatttgaagtgcaTCAAAACcttaaactaaaacaatacccattcttgtcttaggacaacttttatgctccacttcaaatgttgactacgcTATATAAagagtttgtttgcaaaaacaggtaactccatttttaacatttgtcacgtttttttttttcattgttcattccagttaatctcaaTTAAACTGCCGTTGGCTTATTTTTActgggttaaaaaaaaccttaacattataaaatacatgatttttggaaaaaaaaatgattttcagctttttgcaaataatctctctctctctctgtgagtgtgtgtatacatatacatatactttttgtacacacacacacacatatacatatattgcaGTGCCTACAGTGCTTACAGCCTAgatgacaaaaactaaaaattgtaTACAGGTAAAGAGGAAATGTGTTACAAGATACAGAGTTGTAACAAGTACTTAATTGTAATAAACGCAcagattatttataaatgttattgtatCCGCCGGCAGCCATCTGGATTGTAACGGTTTTGATATATAGCACTAATACTGATTTTGACAAATTTTGGCAACTAAGCATTAAAGACAACTGTAACACAGATATTGTAgacagtgtttatttttgaacagaacaaaagtttcatttgcaaaatgtttttgcaaaatttCCTTTTCTGTACACATCTTTGTGTTCTGCCTTGCAGTGCTTATGTAACACTGTGTTATTTACAAAGGggtgtattaaaatgtttccatgtgcatttga
>XM_043237875.1
GACGGACGGAGCAGAGCACACTTTAACATGCATCCTGACAGCTCATCAAAACACTGGCCATTCTCCCATTACATAGGCTGGAACGGGGATCAAATCaagcaataaaatgttattttgggaTTCTTGCCGACTCAGAAACCAAGCCTTACAGTGGACCATCTGTTGATCAACTAAACATCGATTGCAACAGGTGCTTGTGCTCGGTGCCTGGTATGTTTTGGCCAGTTGCCTGTCTGTGCTAAAACAAGGGTTCAAAAGTCCTCGGCTGACTCACCGTTGGCAGTCCAGAGAGACAGTGTGGCTAACTGCCTCTCTCGCAAAGTACAGTCTACAACACTGTGCTGCATCACGTTTCAGTATCGATGACTGAGGAGTGCAACATGACTCGCATCAATAGCTCCCTGTTGATGATAAGACAGCACTGAACCCGTCCGCCTTCGCTATGTCCGAGTATCCCGAAGGAGACAGTTGTCTACTTCAGCTGCAGGAAGTGGACTCCAACAGGGTGGGAGGTCACGTCCTCTCTCCTGCCTTTAACTCTTCCTCTCCATCTCTGTCGGTGGAGAGCCACCCCATCTGCATCCCATCACCCTACACAGACCTCAGCCATGACTTCTCCACCCTGCCCTTCTACAGTCCTGCTCTGCTGGGGTACGGCGCGTCGCCTCTCTCCGACTGCCCATCTGTGAGGCAGTCGCTAAGCCCCTCCCTCTTTTGGCCACCTCATAGCCATGTTTCTTCGATTGCGTTGCATCAGCAACAGAATCGACTGCAACAAAACCACCCAGCTGGTGGGACCTGGGCAGATCTTACACCACATGATCACAGCGAAGAGGAATACTGCAAACCGCTGGCGAAGAGGGTAGGAGATGCAGAGGAGAGTTCTACTTCTTTGAGAGGTAAAGCTGACATGCACTACTGCGCCGTCTGTAGCGATTACGCCTCCGGGTATCATTATGGCGTGTGGTCGTGTGAAGGATGCAAAGCCTTCTTCAAGAGAAGTATACAAGGACACAATGACTACATCTGCCCCGCCACCAACCAGTGCACCATCGACAAGAACCGCCGCAAAAGCTGCCAGGCCTGCCGTCTGCGAAAATGTTATGAAGTTGGAATGATGAAATGCGGGTTACGGCGAGATCGTGGTAGCTACCAACAAAGAGGAGGACAGCAGAAACGGCTGGCACGATTCTCTAGCAGGATGAGAACATGTGGCCCGAGATCTCAAGAAATCAAAAGTGTCCCACGACCCCTCGGTGGAAATAAGGTGCTTAATATAGCCTTGAGCCCCGAGGAACTAATTGCTCGAATCATGGATGCAGAGCCACCCGAGATTTACCTCATGAAAGACATGAAGAAGCCATTCACTGAGGCCAACGTCATGATGTCGCTGACCAACCTGGCCGACAAAGAGCTTGTTCACATGATCAGCTGGGCCAAGAAGATCCCAGGTTTTGTGGAGCTCAGTCTTTTTGACCAGGTCCATTTGTTGGAGTGCTGCTGGTTGGAGGTGCTGATGCTGGGACTGATGTGGCGGTCCGTTAATCACCCTGGAAAGCTCATTTTCTCCCCAGACCTCAGTCTCAGCAGGGACGAAGGCAGCTGTGTGCAGGGGTTTGTGGAGATCTTTGATATGCTGCTGGCAGCCACATCCAGGTTCAGAGAACTGAAGTTACAGAGAGAGGAGTATGTGTGTCTCAAAGCCATGATCCTGCTCAACTCCAACATGTGCCTGAGTTCGTCTGAGGGAGGAGAGGAGCTGCAGAGCCGGTCGAAGCTGCTGTGTCTGCTGGACTCGGTGACGGATGCTCTGGTGTGGGCCATCTCCAAGACGGGCCTGAGCTTCCAGCAGCGCTCCACCAGACTGGCTCATCTGCTCATGCTGCTCTCCCACATAAGGCACCTCAGTAACAAAGGCATGGACCACCTCCACTGcatgaagatgaagaagatgGTTCCTCTGTATGACCTGCTTCTGGAGATGCTGGATGCTCATATCATGCACAGCTCCCGTCTGTCTCACTCCGGCCCTCGAGTGGCTCCTGCTCCTAAAGAGAGCAAAGTCGCTCAGGAGGCCTTCGCCTGCACTTCTCAGCATGGAGAGACCTTAGGAGCCTCAACCATTTCTGTGCTGAGGAATGATCTATAGTTTTGGGAGAATGGACAACAAAAACAGCCGCGCAGAAAAAGTGGAATACAATTTCTCaagctaaaaaacattttctttttaaaaaatttggcGTTTGCTGTGaaatcctctttttctttttttaacagaacTCATTTTGAACACAGTTGTTTTGTTGTATGTAGCCGTGAACACGCAACACAAAGAAAAGTCCTTCACTTTTTACAAAACCTTATTAATTGCCGGTGGTTTAAAAACTGGTTACCATTTGCTTTTTTGAAATGTAACATGTAACACATATCTGAAATCTGCACCACAATCGAATGTACACTTTCTATTTCTACGCTTATCATTTCCTCCTCTTTCTAAAAAGTACATTTGCAACTCTTGCTTTTTGTGAAGGCCAAAAGAAAATCAGCTGCAGCAACTGCTGTAGATAGAGCGACTATTGAAGACGCTGTCAGAACAAACAGATTCGATTCCTTCACTTTCAAAACGACAATATGAGCAGTCAGTGCTGAAGATGAGAGAGGTTTGTATGCAGTGGGAGCAGAGACCAAAGGCTCAGAAGAACTGAATCaagccttttttttctgtcaggaCTTACATTAGTAGGGCCAAATTCAGGACAGCTGGATGGATGTTATGTTTGCATCTATTACTTTTCACAAAACAGAAGCTTGTTCATCCTGCTCTCTACCCAGTAAACCCTTTAACACCATAACAGCCTTGTACaaagcatttatacattttctaaagacaGCTCAATCGATTGCTACTATTCCACTGTGAAAATCTGTTTGTAAGATGCACCATATGTACCAAAAAAGTACTTGTGATATTGCACTTTAATATTTCTCTGAACTATCTGAAGCCCTATCTTGagaattatatatacagtagtcaacatttgaagtgcaTCAAAACcttaaactaaaacaatacccattcttgtcttaggacaacttttatgctccacttcaaatgttgactacgcTATATAAagagtttgtttgcaaaaacaggtaactccatttttaacatttgtcacgtttttttttttcattgttcattccagttaatctcaaTTAAACTGCCGTTGGCTTATTTTTActgggttaaaaaaaaccttaacattataaaatacatgatttttggaaaaaaaaatgattttcagctttttgcaaataatctctctctctctctgtgagtgtgtgtatacatatacatatactttttgtacacacacacacacatatacatatattgcaGTGCCTACAGTGCTTACAGCCTAgatgacaaaaactaaaaattgtaTACAGGTAAAGAGGAAATGTGTTACAAGATACAGAGTTGTAACAAGTACTTAATTGTAATAAACGCAcagattatttataaatgttattgtatCCGCCGGCAGCCATCTGGATTGTAACGGTTTTGATATATAGCACTAATACTGATTTTGACAAATTTTGGCAACTAAGCATTAAAGACAACTGTAACACAGATATTGTAgacagtgtttatttttgaacagaacaaaagtttcatttgcaaaatgtttttgcaaaatttCCTTTTCTGTACACATCTTTGTGTTCTGCCTTGCAGTGCTTATGTAACACTGTGTTATTTACAAAGGggtgtattaaaatgtttccatgtgcatttga

Function


symbol description
esr2 Enables several functions, including estrogen receptor activity; estrogen response element binding activity; and nuclear receptor activity. Involved in cellular response to lipid and regulation of transcription, DNA-templated. Located in mitochondrion and nucleus. Implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); hypospadias; neurodegenerative disease (multiple); and ovarian dysgenesis 8. Biomarker of several diseases, including Alzheimer's disease; Crohn's disease; aortic valve stenosis; autoimmune disease (multiple); and urinary bladder cancer.

NR:

description
estrogen receptor beta 1

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0043401 steroid hormone mediated signaling pathway biological_process
GO:0030520 intracellular estrogen receptor signaling pathway biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0005496 steroid binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0008270 zinc ion binding molecular_function
GO:0030284 estrogen receptor activity molecular_function

KEGG:

id description
K08551 ESR2, NR3A2; estrogen receptor beta

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043237874.1 True 3808 mRNA 0.44 11 17397135 17410852
XM_043237875.1 False 3804 mRNA 0.44 11 17397135 17410852

Neighbor


gene id symbol gene type direction distance location
jag2b jag2,jag2b,LOC107718403,LOC107755239,LOC107601898 coding upstream 48265 17308293 ~ 17348870 (+)
nudt14 nudt14,LOC107755236,LOC107718404,LOC107701483,LOC107683965 coding upstream 103499 17266457 ~ 17293636 (+)
brf1b brf1b,LOC107718407,LOC107683968,LOC107701485,LOC107755207,LOC107560373 coding upstream 220638 17122433 ~ 17176497 (+)
ppp1r13bb LOC107560381,LOC107718410,LOC107755206 coding upstream 314015 17040857 ~ 17083120 (+)
rd3l rd3l,LOC107697292,LOC107560380,LOC107743985 coding upstream 359978 17033921 ~ 17037157 (+)
LOC122342653 l3hypdh,LOC107684001 coding downstream 72581 17483433 ~ 17490295 (+)
nmu nmu,LOC107684000,LOC107755222,LOC107568121,LOC107701461,LOC107718432 coding downstream 154601 17565453 ~ 17578804 (+)
clocka clock,clocka,LOC107701480 coding downstream 171218 17582070 ~ 17630822 (+)
kdr kdr,LOC107755244,LOC107665394,LOC107683984,LOC107718422 coding downstream 233583 17644435 ~ 17665897 (+)
LOC122343009 zgc:65851,LOC107670379,LOC107668750,LOC107599600,LOC107708255,LOC107755851,LOC107573085 coding downstream 394988 17805840 ~ 17811463 (+)
G29200 NA non-coding upstream 11455 17385289 ~ 17385680 (+)
G29192 NA non-coding upstream 102495 17294375 ~ 17294640 (+)
G29181 NA non-coding upstream 176519 17220257 ~ 17220616 (+)
G29178 NA non-coding upstream 177621 17219142 ~ 17219514 (+)
LOC122342667 NA non-coding upstream 278029 17090539 ~ 17119106 (+)
G29272 NA non-coding downstream 142981 17553833 ~ 17554190 (+)
LOC122342426 NA non-coding downstream 256298 17667150 ~ 17669761 (+)
LOC122343158 NA non-coding downstream 299203 17710055 ~ 17711711 (+)
G29305 NA non-coding downstream 327215 17738067 ~ 17739667 (+)
G29306 NA non-coding downstream 334676 17745528 ~ 17746317 (+)
atp5mj NA other upstream 356305 17038419 ~ 17040830 (+)
G28982 NA other upstream 922754 16473898 ~ 16474381 (+)
G28899 NA other upstream 1411409 15985219 ~ 15985726 (+)
G28891 NA other upstream 1555280 15841372 ~ 15841855 (+)
cdkn1d LOC107699204,LOC107719868,LOC107562144,LOC107601015,LOC107758204,LOC107687563 other upstream 1741857 15565499 ~ 15655278 (+)
G29526 NA other downstream 889563 18300415 ~ 18301189 (+)
G29545 NA other downstream 1025608 18436460 ~ 18461317 (+)
G29642 NA other downstream 1472327 18883179 ~ 18886402 (+)
G29814 LOC107660256 other downstream 1879368 19290220 ~ 19342911 (+)
G29835 NA other downstream 2320410 19731262 ~ 19786128 (+)

Expression



Co-expression Network