tmc2a (tmc2a,tmc1,LOC107684381,LOC107596032,LOC108437175,LOC107730318,LOC108259782)



Basic Information


Item Value
gene id tmc2a
gene name tmc2a,tmc1,LOC107684381,LOC107596032,LOC108437175,LOC107730318,LOC108259782
gene type misc
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056703.1
NCBI id CM032072.1
chromosome length 32833783
location 24265464 ~ 24277304 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>TU57931
CCAGGGGGCCTGTCACTCGAGCACCAGGCCCCAGGGGACCTGGACCTCTACCTGGCCAACCAGGGGCAGGCAGGGGTCAAGGGCCACCGCCTAGACGGCAGTAATGTGTGATCTATTCATATTATGTGCTCTGTTGAACTACGCACTCTATAATTTATGTAAACACTGGTTTGtttcattatataaatgaatatttaaagatgAAGATACTTGGAGATAGCATAATAATTATCATACATTCCTTTGCAGTAAATTGCATATATCATATACATGC
>TU57934
ATTGGAAATGCTGAGACAGCCGACAATAAATACGCCTCCATCACCACCAGCTTCAAAGAGTCCATTGTGGATGAACAGGAGAACCAAAAGGATGAGAACATTCATTTAAGGAGATTCCTACGTGTCCTAGCCAACTTTCTCATCACCTGTACCCTGGGAGGAAGTGGATATCTCATCTACTTTGTGGTCAAACGTTCCCAAGAGTTTGCCAACATGGACAACCTCTCATGGTATGAGAAGAATGAGCTGGAGATCATCATGTCACTGTTGGGTCTGGT
>TU57951
GCGCTAAAAAACCAGCAGCCGGTAAGAGGGGCAAAGCAGCCGCCAGTGAGGAcgaagatgaggatgatgaaCCTCCAAGGGGTCGCCGGGCGGCCAATAAAAAGAAAGCGGCGCAGGTTGATGAAGAAGACAGCGATGACGATATTCCACAGAGGAGATGTGCTGGGAATAGGAGAAGAGGAAAAGTACGTGAGAGTGGGCGAGATGGGGAAAATGAGAAGTCCGGGAGAAAAAACAGGAGAGGCG
>XM_043239462.1
GTTCAAGGACCTATTTGGCTAAAATGATTAACTTGCAGATTAAAAACAGCTCATGGGGTAAGGTGCTGAAAAACATAGAGGCAACCAATCCAATGCAAGAATGCAGAAGAAGTTCAGTTGTCTGTGCACACCCAAAAAGAAAGCGACAAAAACAGCCAATTGCAGTGCGAAATGCAATTGCTGTTCAGGGTTAGATATTAGTGAGTTTACATGTGCTATTAATTCTCTTAATAAATGAATTCTCTCTACTCTCACTTGGCACGAGTGTGAGATTCTTTTAGCAGTCCATTTAGTTTAACACGAATATGCCTTTATTCACATACcattcaaatgatttaatttgtcattttattatagcTAGATACTGTATATGCACATAGATGTGCAGGAATGTacattgtttttatcttttcacaCCGATGAGCATGTAATGACTTGCCGGTGAAAACTGAGATGCTGTGTCATCTACCAGGTGTCATGGTGCAGACGAGACAGGAGATCACATATATCTGTTTGTCTGCTTAGAGTTTCACTGTTCCTGAGTATCTGCATGTGTGTCTGCCTTCAATGGGAAAGAGGGACTGTACATACAATACGTACCGGTTTAGGCCCCCtagtttaaaatgacaatgtcGGAGTGATGGTTGTCGGCAGTCGTCTGTCACTGCAAACTTTCATTTGGACGTGTTTACGCTGCATTTACTTTGTAGCCGCAGAAGCTGCAAAGAAAGCGCACGTTAGAATGAAAGAGCAAAGCTTAATATactgtgaaatgtgtttaattgcCTTTGAAGGAAAACCTAAACCTTCATTAAATCTTTAAGGTGCCTCTTCTTGTGACAGCAGCATTAGGTGTCATGTGTCTCAATGAGTGAGAGTGCATCGAACAGTTTAAACGGATGCAGCGTGCCATCCAGAATGCTTTGTGATCGGAACATTAAAACACGGATGGAATTCGAATTGCTCATCCGAGGGACGATAATATAGTTATACTTCCTGTAAGTTCTCagctcatttttcttttttttttcatttctctttttatttcatttgggATCCAGTCCTGTCTTAAATACGGCTGTTTTTGTCTTAAAAGCTTAAGTTGAACTCAAATCGTCTAGACAAACCGTTCCAGttcatattaatatagtaatatcAGTCGCTATTACACACGTGAGGTGTTGCTATGGCAACGGGGAGTCAGTTACTGGAGAGCAGCTGCACACCTGTGCAGTAATTTGTTAGACCACAGGTGCAAGTAAAGAAATTCAGAGACTAAACGAGTTTAGAAGGGCAGAGAAATGCCGAAGAAAAGTGATACATCGAGAAAACTGGAAGACGtgggAATAGATATTGATGGAGATGCAGAGAGCGCTGAagAGGACAAGAAAGCAAAAGGCAAGGGCGCTAAAAAACCAGCAGCCGGTAAGAGGGGCAAAGCAGCCGCCAGTGAGGAcgaagatgaggatgatgaaCCTCCAAGGGGTCGCCGGGCGGCCAATAAAAAGAAAGCGGCGCAGGTTGATGAAGAAGACAGCGATGACGATATTCCACAGAGGAGATGTGCTGGGAATAGGAGAAGAGGAAAAGTACGTGAGAGTGGGCGAGATGGGGAAAATGAGAAGTCCGGGAGAAAAAACAGGAGAGGCGGAAACAAAAAGCAGAAGGATGGCAAGGGCAAAGGAAAAGACAAAGACAATGACAAAGACAGCGACaaagatgaaaagaagaaaaagaacagcAGTGGTGATGATTCCAAATCAGACGAAGAGGAGGAGTCCATGTCTGAAGGAGAAATGGCCAAACTgatggaggaggtggaggagaagaaaaaactgATAGCAAACATCAGGAACAAGCCCTGGCGGATGAGAAGACGGCTGAAAGTCCTCAAAGAGGCTCAGCAGTTTGTGGATAAATTTGAAGGTGCTTTGGGAAAAGGGAAAGGCAGGAAACTCTATGCCTACAAAGTCATGATGATGAAGAAATGGATAAAGTTTCAAAgagattttgaaaattttagGACGGCTTGCATCCCATGGGAGCGGAAAATAAAGGAAGTTGAGAGTCACTTTGGCTCCTCTGTTGCTTCATACTTTATTTTCCTCCGTTGGATGTACGGCATGAACTTGGTCCTCTTCAGCTTAACCTTTGGCCTGGTTGTGATACCAGAGGTTCTCATGGGACTTCCATATGGGTCCATTCCTCGGAAAACTGTGCCTACAGAAGAACAAGACACTGCTATGGACTATTCTGTTCTCACAGATTTCAATGGTTACTGCAAGTACTCAGTACTTTTTTATGGGTACTATAATAACCAGAGAACCATTGGCTTCCTGAAGTTTCGCCTCCCTCTGTCTTACCTCCTGGTGGGCATTGGGACCTTCGGGTATAGCCTCATGGTTGTGATCAGAACGATGGCTAAAAACGCAGATGTAGGGGGAGGGGATGGAGAAGACAATGAGTTCACCTTTGCCTGGAAGATGTTCACCAGCTGGGATTATCTTATTGGAAATGCTGAGACAGCCGACAATAAATACGCCTCCATCACCACCAGCTTCAAAGAGTCCATTGTGGATGAACAGGAGAACCAAAAGGATGAGAACATTCATTTAAGGAGATTCCTACGTGTCCTAGCCAACTTTCTCATCACCTGTACCCTGGGAGGAAGTGGATATCTCATCTACTTTGTGGTCAAACGTTCCCAAGAGTTTGCCAACATGGACAACCTCTCATGGTATGAGAAGAATGAGCTGGAGATCATCATGTCACTGTTGGGTCTGGTGGGTCCAATGCTCTTTGAAACTATTGCTGAGCTGGAGGAATACCATCCACGTATAGCTCTCAAGTGGCAGCTTGGGCGTATATTTGCACTCTTCCTTGGCAACCTCTACACATTTTTGCTGGCTCTATTTGATGAGGTCAATGCGAAACTTGAAGAGGAGGAATCAATAAAAAATGCCAGCATTTGGTTCATGAAGGAGTATTACGCCAACTACTCAGCCAACAACCCTAATGACACAGGCACTCCACCTCCTATCAATCCTGGTGATGTCATCAGAGGCCCATGCTGGGAAACTACAGTGGGAATAGAGTTTGTGAAGCTGACTGTATCAGATATACAAGTGACTTATCTGACCATCCTCATTGGTGACTTCCTGAGAGCGCTGATTGTGCGTTTCTTGAACTACTGCTGGTGTTGGGATCTGGAAGCTGGCTGGCCCTCCTATGGTGAATTTGATATAAGTGGCAACGTGCTTGGTTTGGTGTTTAACCAAGGAATGATCTGGATGGGGGCATTCTATGCTCCCGGTCTGGTGGGTATCAATGTACTGCGACTCCTGACCTCCATGTACTATCAATGTTGGGCTGTAATGGCCTGTAATGTCCCACATGAGAGGGTCTTTAAAGCTTCCAAATCCAATAACTTCTACATGGGCCTGTTACTGCTCATCCTTTTCTTGAGTCTCCTGCCTGTGGTTTACACCATCATGTCTTTGCCTCCCTCCTTTGACTGTGGACCCTTCAGTGGGAAAGAGCGAATGTTTGACGTCATTATGGAGACCATTGATCTGGATCTACCTGCTTTTATGGGGACGCTCTTTAGCTATGTAGCAAACCCTGGACTCATTATACCAGCAGTTCTTCTGATGGTTCTGGCCATTTACTACCTGAATTCTGTGTCAGAGGCCTATAAGAACTCCAACATGgagctaaaaaagaaaatgcagatgGCAAGAGATGAGGAAAAGAACAGACGGAACAACAAAGACAGCACTAACCAGGTGATGAAGGACCTGGAGGATCTACTTCCAAATCGCTCTCTTGTGCACCCTGCTCCTCCAGAGAAAAGTGCAGAAAAAAGACACGACCAAGGTGGAAAATCTCCAAAAGTGAAACCAGGCACAGCTGGTGTGCATCTGCAGAAAGACGTGTCCCTCGCGTCAGCTAATCCTAACGCCAGGGGGCCTGTCACTCGAGCACCAGGCCCCAGGGGACCTGGACCTCTACCTGGCCAACCAGGGGCAGGCAGGGGTCAAGGGCCACCGCCTAGACGGCAGTAATGTGTGATCTATTCATATTATGTGCTCTGTTGAACTACGCACTCTATAATTTATGTAAACACTGGTTTGtttcattatataaatgaatatttaaagatgAAGATACTTGGAGATAGCATAATAATTATCATACATTCCTTTGCAGTAAATTGCATATATCATATACATGCAGTGGCCCCAAAGTGAATTTGGACACTCAGTCACTTCCACTAATGCTGGACATACAAAGAgtacaatattttttgtcttaAGTTTGAACAGTATATagattgttttatcatttaaataaaagattttgctTGGATATTTGTGTCTTTTAATGCAGTGAGTTGTATTTTTGATTGTGTCTTAAGTGTTTAAATTCTCTTTGGGCCTACTGTATGTGTTATGTGTTCAATGCATGTGTATAATACCACCGCATATAACTGCTTTATTAGCAAACTACA

Function


symbol description
tmc2a Predicted to enable mechanosensitive ion channel activity. Acts upstream of or within detection of mechanical stimulus involved in sensory perception of sound. Predicted to be located in membrane. Predicted to be integral component of plasma membrane. Is expressed in inner ear and neuromast. Orthologous to human TMC2 (transmembrane channel like 2).
tmc1 Predicted to enable mechanosensitive ion channel activity. Predicted to be involved in detection of mechanical stimulus involved in sensory perception of sound and vestibular reflex. Located in stereocilium bundle. Is expressed in anterior crista; inner ear; lateral crista; neuromast; and posterior crista. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 36; autosomal recessive nonsyndromic deafness 7; and sensorineural hearing loss. Orthologous to human TMC1 (transmembrane channel like 1).

NR:

description
transmembrane channel-like protein 2 isoform X3

GO: NA

KEGG:

id description
K21988 TMC; transmembrane channel-like protein

RNA


RNA id representative length rna type GC content exon number start site end site
TU57931 False 274 lncRNA 0.43 1 24265740 24266013
TU57934 False 278 lncRNA 0.45 3 24269863 24270496
TU57951 False 246 lncRNA 0.54 1 24275360 24275605
XM_043239462.1 True 4510 mRNA 0.43 20 24265464 24277304

Neighbor


gene id symbol gene type direction distance location
LOC122345102 LOC107691787,LOC107600611,LOC107684345,LOC107595997,LOC107684346 coding downstream 746 24253333 ~ 24264718 (-)
pcsk5a pcsk5a,LOC107728213,LOC107691788,LOC107684380,LOC107730328,LOC107596014,LOC107600598 coding downstream 12833 24230346 ~ 24252631 (-)
ntrk2b ntrk2b,LOC107691713,LOC107728215,LOC107600581,LOC107730333,LOC107596017,LOC108443857,LOC103044160,LOC108259739,LOC107684341 coding downstream 77979 24166208 ~ 24187485 (-)
tmem150ab tmem150ab,LOC107684378,LOC107600579,LOC107572579,LOC107728219,LOC107691718 coding downstream 167290 24092380 ~ 24098174 (-)
fkbp6 fkbp6,LOC107695148,LOC107600609,LOC107691791,LOC107728208,LOC103911693,LOC107730305 coding downstream 178960 24082446 ~ 24086504 (-)
LOC122345313 LOC107681049,LOC107706956,LOC107574963 coding upstream 21226 24298530 ~ 24317831 (-)
cd180 LOC107742410,LOC107681052,LOC107600612 coding upstream 129691 24406995 ~ 24409513 (-)
pmchl LOC107683707,LOC107575048,LOC107738923,LOC107596031,LOC107730319,LOC107684382 coding upstream 253104 24530408 ~ 24530963 (-)
npr2 npr2,LOC107559735,LOC107746469,LOC107730344,LOC107684353,LOC107595992,LOC107683705,LOC108260050 coding upstream 268844 24546148 ~ 24585135 (-)
tprn tprn,LOC107559738,LOC107746472,LOC107684357,LOC107595990,LOC107730352,LOC107697983,LOC107734963 coding upstream 319783 24597087 ~ 24613743 (-)
G39123 NA non-coding downstream 45937 24218993 ~ 24219527 (-)
G39122 NA non-coding downstream 47034 24218100 ~ 24218430 (-)
G39121 NA non-coding downstream 50304 24214526 ~ 24215160 (-)
G39120 NA non-coding downstream 52705 24212442 ~ 24212759 (-)
G39059 NA non-coding downstream 158201 24101841 ~ 24107263 (-)
G39137 NA non-coding upstream 170 24277474 ~ 24280889 (-)
G39274 NA non-coding upstream 137596 24414900 ~ 24490792 (-)
G39285 LOC107738919,LOC107681053,LOC107600587,LOC107595995 non-coding upstream 193307 24470611 ~ 24479055 (-)
G39296 NA non-coding upstream 242363 24519667 ~ 24520387 (-)
G39298 LOC107683704,LOC107738921,LOC107600589,LOC107595993,LOC107730350 non-coding upstream 244258 24521562 ~ 24522021 (-)
G39113 NA other downstream 64968 24197705 ~ 24200496 (-)
aatf LOC107695156,LOC107730321,LOC107600606,LOC107603183 other downstream 267725 23979664 ~ 23997739 (-)
G38973 NA other downstream 377784 23887303 ~ 23887680 (-)
G38917 LOC107691721,LOC107751254,LOC107564048,LOC107721650,LOC107603186,LOC107663788 other downstream 508876 23751880 ~ 23756588 (-)
LOC122345364 NA other downstream 659716 23602236 ~ 23605748 (-)
anapc2 anapc2,LOC107559737,LOC107730340,LOC107746468,LOC107683706,LOC107595991,LOC107684355 other upstream 310420 24587724 ~ 24594116 (-)
naa38 naa38 other upstream 469368 24746672 ~ 24748610 (-)
LOC122345923 NA other upstream 476898 24754202 ~ 24758668 (-)
G39413 LOC102215562 other upstream 1004582 25281886 ~ 25282286 (-)
LOC122344921 NA other upstream 1284670 25561974 ~ 25568686 (-)

Expression



Co-expression Network