isl1a (isl1,LOC107661270,LOC107708623,LOC107599171,LOC107602011)



Basic Information


Item Value
gene id isl1a
gene name isl1,LOC107661270,LOC107708623,LOC107599171,LOC107602011
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056703.1
NCBI id CM032072.1
chromosome length 32833783
location 15121996 ~ 15128172 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043238532.1
agagatagggaCAAGAGTGGCCCATCAATACTGTGACCAAGCACGGGAGCTCAGCACACACCCCTAACTCTAATCGCAAGCATCTCGATTCCGGGAAGTCCTGCAACACCTCGAACCCTCGGCCACTTTCCCACCTTCTCAGATCAAAACACGGGCACTAAGGGCCTTCTGTCCGGTTTTAAAGTGGACCTAACACCGCCTTACTTTATTGACATGGGAGACATGGGGGATCCGCCAAAAAAAAAGCGTCTAATCTCGTTGTGTGTCGGCTGTGGGAATCAAATCCACGACCAGTATATTCTGCGCGTGTCCCCGGACCTGGAGTGGCACGCGGCGTGTTTGAAATGTGCAGAATGTAACCAGTATCTGGACGAGTCCTGTACGTGTTTTGTGCGAGACGGAAAAACTTACTGTAAGCGGGACTACATCAGGTTATACGGGATCAAATGCGCTAAATGCAACATCGGTTTCAGCAAGAATGACTTCGTGATGAGAGCACGCTCGAAGGTTTATCACATCGAGTGCTTCAGATGCGTGGCGTGTAGCCGGCAGCTCATCCCAGGAGATGAGTTCGCTCTGCGGGAAGACGGGCTCTTCTGCAGGGCCGACCACGACGTGGTGGAGCGGGCAACAATGGGTGCTGGTGACCCATTAAGCCCATTACATCCGGCGAGACCTTTACAAATGGCAGCAGAGCCCATTTCGGCACGTCAGCCTGCGCTTCGACCCCATGTGCACAAGCAACCTGAGAAAACAACCCGCGTCCGGACAGTCCTCAACGAAAAACAGCTCCATACCTTGAGGACTTGTTACAATGCCAACCCTCGACCCGACGCCCTCATGAAAGAGCAGCTCGTTGAGATGACGGGTCTCAGCCCGAGAGTCATCAGGGTTTGGTTTCAAAACAAGCGCTGCAAGGACAAAAAGAGGAGCATACTGATGAAGCAACTCCAGCAGCAGCAACCCAACGACAAAACGAACATCCAGGGGATGACAGGGACTCCAATGGTGGCGACCAGTCCAGAGAGACACGACGGTGGTTTGCAGGCAAACCAAGTGGAGGTGCAGAGTTACCAACCGCCTTGGAAAGTCCTGAGTGACTTCGCACTGCAGAGTGACATCGACCAGCCTGCCTTCCAGCAACTGgTGAATTTTTCCGAAGGAGGTCCAGGCTCGAACTCCACGGGGAGCGAGGTCGCCTCGATGTCCTCGCAGCTGCCAGATACACCGAACAGCATGGTAGCGAGTCCTATAGAGGCCTAGGCGAGTGGATTATCTACTGCACCTGAAGTCCGGCAAAGGACGCGTCCGGGAACCAATCTCAGAGAGAGGCTCGTGAAGTTTCTTCCATCCCTATTTCATTTAGGGCcgctcctgaaaaaaaaaaaaaaaaaaacacaccccaTCCTCCAACTGCACGAGGCCTCTATATCGAAACAACCCTTGGTTGTATTTATACACTGTGATGACAATCATGGGATTTAAACACACTCTCCGACCGAGCGAGTCCAACGAGTGTTGCGAAAAGACCGTTTAAAGTTGCAAACTCCCGCGAAAGTGGACCCAGCCGgcgcacacattcacacaccgAACCTGACATGATGACTGCAGCGCTCCGCGGCCGAGTGGACCTGGTCGGCGACACTTTTGCCAAATAACCCTCCACGTTTTCCCCCCACTTTTATGACAAATCATTGGACCTCTACGGATATAAGTCGCAAGAGAACTCAATctaatatacattcatatagCCTACTTTTGTGCGCGACGCGAGTAGCCTATAATGAAACCATgactgttttattctgtttctatAAAAGACCGAAATGGACTAGTTGACTGAAAGAGGGTATGGCAGCCGAGGTCTACTGCGATTACAGTTTTGTTATATCATATGGTCTCTTTTCAAACATCAAACCCAAGTACTAAAGCATTGCAACAAGGTATACCTCTATTTTGCCACAAGCTGTGTGGGAATTTCATGTGTTCGTGTCCGTCCAAGAACTTTTTTCTTTCCCAAAGATGTGTATAGGTTTAAGTTAAGTTAATATGACCGATTAGCTCTGGAGGTTTCGTTTTGTTCatgtgttacaaaatattttattatttattgtcgAAAGACATGCCACTTTTGTGTACTTTTACTTGCTGAAGAagtaaaaaaagaggaaaagaataCTGTCGACTCCGAATGATCTATCATAATTGACGTTTCCTGTCGTTTGATCAAAGACTGATGTAAGAACAACGCCATATGTAGACTTATCTTCAGGAATATTTGATCAATAAAAATTTGACGTGTACTGTAAGTAAACGGTCGGACACGCGGGGCTTTCTTAAATGTTACTATTTTTGTAGCCTATGTTTCTGGCATGATAATTTGAGGGTTGCTCTTTGTAATGTATCACGCAAAAACAAAACGAGTAGATTAGGCAAGAGAAACAAATCAGTTCTCGTTTGATCAAATAACGCGGTTAACGGCATTGCAGGCCATAgcattcttaaagggacagtccacgcaaaaaatgacaaattcgCCATTAAcatgtttcctttttatttacGAAGAAAGTATTAATACTATGTATTTAAAGACCACTGTGTGATCGAGAAATTCaggaatttaaaaattaaactcaGTTGACAGCGGTGACTCATTTTCACACTGACCTGCAGTGAGTTTGTACAAACAGTTAAGTAACAGAATTAAACCTCAATATGAAACACTCCAGACTTTCAGAAAATTATGTCAGGTGCTAGAACAATGACCTTGACTACTGCTCTGTACATGACCGATCACTATGGGCATTGTTCTGCAGCTTCCATGCTTCCGTTGCGCAAACAATTGTTGCAAATTGAGATACTCGTCATGAATACTGAAGATCTATTCAACACCATATATTACTAAAACATTGTTTAGATATATTTGATTATCATCTTGATTATTATCTTTGATTAccacagaaaatgtttaagataaATATACAAGAGGGGCAGGTACGGCTATTTCTGCACTTTC
>XM_043238533.1
agagatagggaCAAGAGTGGCCCATCAATACTGTGACCAAGCACGGGAGCTCAGCACACACCCCTAACTCTAATCGCAAGCATCTCGATTCCGGGAAGTCCTGCAACACCTCGAACCCTCGGCCACTTTCCCACCTTCTCAGATCAAAACACGGGCACTAAGGGCCTTCTGTCCGGTTTTAAAGTGGACCTAACACCGCCTTACTTTATTGACATGGGAGACATGGGGGATCCGCCAAAAAAAAAGCGTCTAATCTCGTTGTGTGTCGGCTGTGGGAATCAAATCCACGACCAGTATATTCTGCGCGTGTCCCCGGACCTGGAGTGGCACGCGGCGTGTTTGAAATGTGCAGAATGTAACCAGTATCTGGACGAGTCCTGTACGTGTTTTGTGCGAGACGGAAAAACTTACTGTAAGCGGGACTACATCAGGTTATACGGGATCAAATGCGCTAAATGCAACATCGGTTTCAGCAAGAATGACTTCGTGATGAGAGCACGCTCGAAGGTTTATCACATCGAGTGCTTCAGATGCGTGGCGTGTAGCCGGCAGCTCATCCCAGGAGATGAGTTCGCTCTGCGGGAAGACGGGCTCTTCTGCAGGGCCGACCACGACGTGGTGGAGCGGGCAACAATGGGTGCTGGTGACCCATTAAGCCCATTACATCCGGCGAGACCTTTACAAATGGCAGAGCCCATTTCGGCACGTCAGCCTGCGCTTCGACCCCATGTGCACAAGCAACCTGAGAAAACAACCCGCGTCCGGACAGTCCTCAACGAAAAACAGCTCCATACCTTGAGGACTTGTTACAATGCCAACCCTCGACCCGACGCCCTCATGAAAGAGCAGCTCGTTGAGATGACGGGTCTCAGCCCGAGAGTCATCAGGGTTTGGTTTCAAAACAAGCGCTGCAAGGACAAAAAGAGGAGCATACTGATGAAGCAACTCCAGCAGCAGCAACCCAACGACAAAACGAACATCCAGGGGATGACAGGGACTCCAATGGTGGCGACCAGTCCAGAGAGACACGACGGTGGTTTGCAGGCAAACCAAGTGGAGGTGCAGAGTTACCAACCGCCTTGGAAAGTCCTGAGTGACTTCGCACTGCAGAGTGACATCGACCAGCCTGCCTTCCAGCAACTGgTGAATTTTTCCGAAGGAGGTCCAGGCTCGAACTCCACGGGGAGCGAGGTCGCCTCGATGTCCTCGCAGCTGCCAGATACACCGAACAGCATGGTAGCGAGTCCTATAGAGGCCTAGGCGAGTGGATTATCTACTGCACCTGAAGTCCGGCAAAGGACGCGTCCGGGAACCAATCTCAGAGAGAGGCTCGTGAAGTTTCTTCCATCCCTATTTCATTTAGGGCcgctcctgaaaaaaaaaaaaaaaaaaacacaccccaTCCTCCAACTGCACGAGGCCTCTATATCGAAACAACCCTTGGTTGTATTTATACACTGTGATGACAATCATGGGATTTAAACACACTCTCCGACCGAGCGAGTCCAACGAGTGTTGCGAAAAGACCGTTTAAAGTTGCAAACTCCCGCGAAAGTGGACCCAGCCGgcgcacacattcacacaccgAACCTGACATGATGACTGCAGCGCTCCGCGGCCGAGTGGACCTGGTCGGCGACACTTTTGCCAAATAACCCTCCACGTTTTCCCCCCACTTTTATGACAAATCATTGGACCTCTACGGATATAAGTCGCAAGAGAACTCAATctaatatacattcatatagCCTACTTTTGTGCGCGACGCGAGTAGCCTATAATGAAACCATgactgttttattctgtttctatAAAAGACCGAAATGGACTAGTTGACTGAAAGAGGGTATGGCAGCCGAGGTCTACTGCGATTACAGTTTTGTTATATCATATGGTCTCTTTTCAAACATCAAACCCAAGTACTAAAGCATTGCAACAAGGTATACCTCTATTTTGCCACAAGCTGTGTGGGAATTTCATGTGTTCGTGTCCGTCCAAGAACTTTTTTCTTTCCCAAAGATGTGTATAGGTTTAAGTTAAGTTAATATGACCGATTAGCTCTGGAGGTTTCGTTTTGTTCatgtgttacaaaatattttattatttattgtcgAAAGACATGCCACTTTTGTGTACTTTTACTTGCTGAAGAagtaaaaaaagaggaaaagaataCTGTCGACTCCGAATGATCTATCATAATTGACGTTTCCTGTCGTTTGATCAAAGACTGATGTAAGAACAACGCCATATGTAGACTTATCTTCAGGAATATTTGATCAATAAAAATTTGACGTGTACTGTAAGTAAACGGTCGGACACGCGGGGCTTTCTTAAATGTTACTATTTTTGTAGCCTATGTTTCTGGCATGATAATTTGAGGGTTGCTCTTTGTAATGTATCACGCAAAAACAAAACGAGTAGATTAGGCAAGAGAAACAAATCAGTTCTCGTTTGATCAAATAACGCGGTTAACGGCATTGCAGGCCATAgcattcttaaagggacagtccacgcaaaaaatgacaaattcgCCATTAAcatgtttcctttttatttacGAAGAAAGTATTAATACTATGTATTTAAAGACCACTGTGTGATCGAGAAATTCaggaatttaaaaattaaactcaGTTGACAGCGGTGACTCATTTTCACACTGACCTGCAGTGAGTTTGTACAAACAGTTAAGTAACAGAATTAAACCTCAATATGAAACACTCCAGACTTTCAGAAAATTATGTCAGGTGCTAGAACAATGACCTTGACTACTGCTCTGTACATGACCGATCACTATGGGCATTGTTCTGCAGCTTCCATGCTTCCGTTGCGCAAACAATTGTTGCAAATTGAGATACTCGTCATGAATACTGAAGATCTATTCAACACCATATATTACTAAAACATTGTTTAGATATATTTGATTATCATCTTGATTATTATCTTTGATTAccacagaaaatgtttaagataaATATACAAGAGGGGCAGGTACGGCTATTTCTGCACTTTCTATT

Function


symbol description
isl1 Enables DNA-binding transcription factor activity, RNA polymerase II-specific; DNA-binding transcription factor binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in cardiac cell fate determination; positive regulation of transcription by RNA polymerase II; and secondary heart field specification. Predicted to be part of chromatin. Predicted to be active in nucleus. Implicated in type 1 diabetes mellitus and type 2 diabetes mellitus.

NR:

description
PREDICTED: insulin gene enhancer protein ISL-1

GO:

id name namespace
GO:0021522 spinal cord motor neuron differentiation biological_process
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0055011 atrial cardiac muscle cell differentiation biological_process
GO:0055012 ventricular cardiac muscle cell differentiation biological_process
GO:0031017 exocrine pancreas development biological_process
GO:0008016 regulation of heart contraction biological_process
GO:0048665 neuron fate specification biological_process
GO:0048936 peripheral nervous system neuron axonogenesis biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K09370 ISL1; insulin gene enhancer protein ISL-1

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043238532.1 False 3019 mRNA 0.46 6 15122000 15128172
XM_043238533.1 True 3020 mRNA 0.45 6 15121996 15128172

Neighbor


gene id symbol gene type direction distance location
fsta fst,fsta,LOC107746798,LOC107599173,LOC107708632,LOC107602023,LOC107661233 coding downstream 98540 15016899 ~ 15023456 (-)
hspb3 hspb3,LOC107746796,LOC107599178,LOC107744878,LOC107602000 coding downstream 202057 14918926 ~ 14919939 (-)
snx18a snx18,snx18a,LOC107599175,LOC107661231,LOC107746794,LOC107744868,LOC107602026 coding downstream 204232 14906584 ~ 14917764 (-)
si:dkey-193c22.1 si:dkey-193c22.1,LOC107661268,LOC107602027,LOC107599182,LOC107744872,LOC107746871,LOC107736603 coding downstream 241923 14876022 ~ 14880073 (-)
wdfy3 wdfy3,LOC107681281 coding downstream 246519 14812557 ~ 14875477 (-)
parp8 parp8,LOC107746800,LOC107661236,LOC107708633 coding upstream 46216 15174388 ~ 15199837 (-)
golph3a golph3,LOC107681169,LOC107552603,LOC107746803,LOC107602021 coding upstream 140504 15268676 ~ 15279272 (-)
mtmr12 mtmr12,LOC107746804,LOC107552602,LOC107708634,LOC107602020 coding upstream 152042 15280214 ~ 15292882 (-)
eef2l2 eef2l2,LOC107681082,LOC107746808,LOC107552597,LOC107676651,LOC108414462,LOC107708638,LOC108255789 coding upstream 322852 15451024 ~ 15457371 (-)
akr1a1a akr1a1a,LOC107602015,LOC107708643,LOC107676648,LOC105901177,LOC108414433 coding upstream 343920 15472092 ~ 15477073 (-)
G36714 NA non-coding downstream 216375 14905385 ~ 14905621 (-)
G36708 NA non-coding downstream 240931 14880865 ~ 14881065 (-)
G36696 NA non-coding downstream 423043 14698736 ~ 14698953 (-)
G36631 NA non-coding downstream 469603 14652095 ~ 14652393 (-)
G36602 NA non-coding downstream 633268 14485814 ~ 14488728 (-)
G36811 NA non-coding upstream 40875 15169047 ~ 15169358 (-)
G36967 NA non-coding upstream 433550 15561722 ~ 15562078 (-)
G36968 NA non-coding upstream 433976 15562148 ~ 15562363 (-)
G36969 NA non-coding upstream 435926 15564098 ~ 15565262 (-)
G36986 NA non-coding upstream 585503 15713675 ~ 15713975 (-)
LOC122345141 LOC107752369,LOC107661250,LOC107567461 other downstream 819615 14292063 ~ 14302381 (-)
znhit1 znhit1,LOC107752359,LOC107661214,LOC106567874 other downstream 839376 14279674 ~ 14282620 (-)
rnf214 LOC107663407,LOC107746393,LOC107599207,LOC107596114,LOC107734124,LOC107661199,LOC107599223 other downstream 1065291 14040982 ~ 14056705 (-)
tmprss13b LOC107746439,LOC107663381,LOC107599230 other downstream 1112460 14001934 ~ 14009536 (-)
LOC122345901 NA other downstream 1273926 13845403 ~ 13848070 (-)
pdzd2 pdzd2,LOC107746802,LOC107681406,LOC107661237 other upstream 77779 15205951 ~ 15264945 (-)
zfr zfr,LOC107746805,LOC107681158,LOC107552600,LOC107602019 other upstream 165684 15293856 ~ 15308440 (-)
npr3 LOC107681138,LOC107746807,LOC107552598,LOC107602007,LOC107708637,LOC107661273 other upstream 221844 15350016 ~ 15367413 (-)
alkbh2 alkbh2,LOC107746816,LOC107552593,LOC107676640 other upstream 439847 15568019 ~ 15578967 (-)
cenpv cenpv,LOC107718355,LOC107676655,LOC107746825,LOC107680877,LOC107553589,LOC107552586 other upstream 575361 15703533 ~ 15709430 (-)

Expression



Co-expression Network