CI01000004_15483948_15538159 (INSR, INSRA)


Basic Information

Item Value
gene id CI01000004_15483948_15538159
gene name INSR, INSRA
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000004
NCBI id null
chromosome length 17451736
location 15483948 ~ 15538159 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000004_15483948_15538159.mRNA
TGCTCAAGTAAAGACATCAGAAATAACGTGACCAACCTGCGGGTGCTGGAGAACTGCACCGTGATCGAAGGCCACTTAAAGATCCTACTCATGTTCACGACCAAACCGGAGGATTTCCGTGGCCTGAGTTATCCCAAGCTGACAGTAGTGACGGACTACTTTCTCCTGTTCCGTGTCTATGGCCTAGAGAGCCTCAGCGACCTGTTTCCCAACCTCACGGTGGTGCGAGGCAATAATCTCTTCTTCAACTATGCGCTCGTGCTGTTCGAGATGCTGCAGCTGAAGGAGATCGGTCTTCACAGTCTGATGAATATCACCCGTGGGGCCGTGCGTGTGGAGAAGAACCCAGACCTCTGCTACCTCTCTACCCTCGACTGGTCCATGATCCTTGACTCGGTGGAGGACAACTACATTGTGGCCAATAAAAATGATCGAGAGTGCGGAGATGTCTGCCCCGGCACGGTTCAGGGCAAAACCACCTGCCCCCTCACCACCATCAACGGGGACTTCAGCGAGCGCTGCTGGAACCAGAGGCATTGCCAGCGAATGTGTCCATCCTCATGCAAGCACCGTGCCTGCACAAGAGACAACCAGTGCTGCCACGACCAGTGTCTGGGCGGCTGTTCGGAGCCCAACTCATCGCGCAAATGCGTGGCCTGTCGCAACTACATGCACAATAACATCTGCGTTGAAAAGTGCCCAGCTGGTTTCTACACCTTTAAGGGCTGGCGCTGCGTCAACTTCAGCTTTTGCCAGGAGCTCCACAACAAGTGCAAGCAGGGCAAAGGTGACTGCCACGAATACGTCATTCATGATGGTGCCTGCATCCCAGAGTGCCCTTCTGGGTACACCACTGTAAACTCCACTACGTTGAACTGCACCCCGTGCGCTGGCCTCTGTCCCAAAGTGTGCATGGGGCTGAAGACAGTTGACTCAGTCACTGCGGCGCAGGCTCTGAGAGGATGCACTGTGATCAATGGCAGTTTGGTCATCAACATCCGCGGAGGGAATAACATAGCCGCAGAGCTGGAAGCTAACCTGGGCCAGCTGGAGGAGATCACCGGCTACCTGACAGTGCGACACTCATATGCCCTAGTCTCCCTATCTTTCCTTCGCAAGCTCCGAATCATCCATGGAGAGACACAGGAAGTTGGGAATTATTCATTCTACGCGCTCGATAACCAGAACCTGCGTCAGCTGTGGGACTGGAACAAACACAACCTGACCATCCAGCAAGGTCGCATGTTTTTCCATCATAACTCCAAACTTTGCATGTCGGAGATCCGGAAGATGGAGGAGGTGACTGGCACTAAGAACCGGCAAACAAAGAATGACATTGTCTCAAAGACCAATGGAGATCAGGCTTCATGTGAGAGCCAGGTTTTGAAGTTCACACAGATTCGCACACTTTCAGACAAGATCATAATTAAATGGGAACCTTTCTGGCCGCCAGATTTTCGAGACCTCCTGGGATTCATGGTTTTATACAAAGAGGCGCCATATAAGAATGTGACTGAGTTCGATGGTCAGGATGCATGTGGCTCTAACAGCTGGGTCATAGCAGATGTGGACCCTCCGCCTCGCGCCACAGAGGGAAAAGAACAGCAGGAGCCTGGATACCTCATCCTTCCTCTGAAGCCATGGACGCAGTATGCCATCATGGTCAAAACCCAGCTCTCCGCTTCTGATGAGCACCAGGTCCATGGGGCAAAGAGCGAAATCATCTATGTCCGCACCAATGCTACCAAACCCTCTGTGCCCCTGGACCCCATATCCTCGTCAAACTCCTCATCTCAGATCATTCTGAAGTGGAAGCCTCCTAACGATCCAAACGGAAACATCACACACTACTTAGTCTTCTGCCAGCAGCAACCAGAGGCCAGCGAGCTCTACAAGTTTGATTACTGTCAGAAAGGTATGAAGCTGCCCACCAGAGCTCCCACACAAGTGGACAACGAAGAGGAACAGAAGTGGAACCAAACCGAGGAGCAAGGCCAAGATAGCCGCTGCTGCGCCTGCCCCAAAACAGAGAAACAGCTGAAGAAAGAGGCAGAAGAGACAGAGTACCGCAAAACCTTTGAGAACTACCTCCATAATGAAGTCTTTGAGCTCAGGACATCAAGACAGCGCAGATCTCTGGTGGGCATTGCCAATAGGACCTCCTCTCGTCTTTTCACTACACCCTCCTCGTTGCCCAATGGCTCTGCCACTCGTAGCCCAGAGGAAGAAGCAGAGGCCAATAAGATTTCACTGATTGTTCGTGCCAAGGAGTCGACAGTCATCTCCAATCTGCGCCATTTCACCAGCTACCAGATAGAAATCCATGCCTGCAACCATGAGAGTGACCCCACTCGCTGCAGTATGGCGGCCTACGTCAGTGCCCGCACCATGCCCGAAGAAAAAGCTGATGACATTGTGGGTCCGATAACCTATGAGGTGTCGGAGTACTCTGTACACATCAGGTGGATGGAGCCCAAGGCCCCTAATGGCATGATTATTCTCTATGAAGTCCATTACAAGAGACTGGGAGATACAGAGGAGCTGCACCACTGCGTATCCAGGAAGAATTATATTGCAGACGGAGGCTGTAAGCTGAGAGTGGTGCACCCTGGGAACTATACAGTGCGGATCAGAGCAACCTCCTTGGCAGGCAATGGATCGTGGACAGAGCCAACACACTTCTATGTTCAGGACCTACGTGTGGACCCATCCAACATGCTGAAGATTGTGATTGGTCCGGTGATCTGTGTCTTTTTACTCCTTGTGATGGGAGGTGTGGGCTTTTTCATGTTCAAGAAAAAGCAAACAGAAGGTCCAACTGGGCGACTTTATACCTCCCCAAATCCAGAGTATTTCAGCCCAGATGAGGTGTATGAGCCAGACGAGTGGGAGGTGCCCCGTGAAAAGATTAACCTATTGCGAGAGTTAGGCCAGGGATCTTTCGGCATGGTGTATGAGGGCATCGGAAAGGACATAGTCAAAGGCGAGCCACAGACCCGTGTTGCAGTGAAGACGGTTAACGAGTCGGCCAGCCTCAGAGAGAGGATCGAGTTCCTCAACGAAGCTTCTGTGATGAAGGCGTTCAGCTGCCACCATGTGGTGAGGCTGCTGGGGGTGGTGTCTAAAGGCCAGCCCACCCTAGTGGTGATGGAGCTCATGACACATGGAGATCTGAAGAGTTTCCTGCGTTCTCTCAGACCTGACTCAGAGAATAACCCAGGTCGGCCTCCTCCAACGCTGAAAGAGATGATTCAAATGGCCGCAGAGATAGCAGATGGCATGGCTTACTTGAACGCCAAGAAGTTTGTGCACCGAGACCTTGCTGCCAGGAACTGCATGGTGGCCGAAGACCTGACCGTAAAAATTGGAGATTTTGGCATGACGAGAGACATTTATGAGACGGATTACTACAGAAAGGGTGGGAAGGGCCTGCTTCCTGTGAGATGGATGGCCCCTGAGTCGCTGAAGGATGGAGTCTTCACCGCTCATTCAGACTGCTGGTCGTTTGGTGTGGTGTTATGGGAGATCAGTACTCTGGCTGAGCAACCCTACCAGGGGCTGTCCAATGAACAAGTCCTTAAGTTTGTGATGGAGGGAGGATTCCTGGACAGACCTGACAACTGCGCAGACAGATTGCATAACCTGATGCAGATGTGCTGGCATTACAATCCCAAAATGAGGCCCGCCTTCCAGGAGATCATCGAGATGCTCCGGGAGGATCTGCATCCCTCGTTTCAGGAGGTCTCCTTTTTCTACAGTGAGGAGAACAAGCCGCCCGAGACGGAAGAGTTTGATATGGACCTGGAGAACATGGAGAGCATCCCGCTGGACCCTTCCTCGTACTCTCAGAGGGAGTGCTGTCTAGATGGGGATGAGGGCTCATCCGTGGGCCTTCGAGGGAGTTATGAGGAGCACGTGCCGTATACGCATATGAACGGCGGCAAGAAAAACGGACGCATCTTATCCCTACCCCGATCTAACCCTTCT

Function

symbol description
insra Predicted to enable insulin receptor substrate binding activity and insulin-activated receptor activity. Acts upstream of or within with a positive effect on glycolytic process. Acts upstream of or within with a negative effect on gluconeogenesis. Acts upstream of or within chordate embryonic development and developmental growth. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be part of insulin receptor complex. Predicted to be active in axon. Predicted to be integral component of plasma membrane. Is expressed in several structures, including fertilized egg; immature eye; liver; male organism; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in Donohue syndrome; diabetes mellitus (multiple); familial hyperinsulinemic hypoglycemia 5; and reproductive organ cancer (multiple). Orthologous to human INSR (insulin receptor).
insr Enables several functions, including insulin-like growth factor binding activity; peptide binding activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including positive regulation of cellular metabolic process; positive regulation of intracellular signal transduction; and protein phosphorylation. Located in caveola. Is integral component of plasma membrane. Part of insulin receptor complex. Colocalizes with nuclear envelope and nuclear lumen. Implicated in Donohue syndrome; diabetes mellitus (multiple); familial hyperinsulinemic hypoglycemia 5; and reproductive organ cancer (multiple). Biomarker of Alzheimer's disease; breast cancer; hepatocellular carcinoma; renal cell carcinoma; and seminoma.

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process

KEGG:

id description
K04527 INSR, CD220; insulin receptor

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000004_15483948_15538159.mRNA True 3987 mRNA 0.52 20 15483948 15538159

Neighbor

gene id symbol gene type direction distance location
CI01000004_15456870_15468826 NA coding downstream 15122 15456503 ~ 15468826 (-)
CI01000004_15434959_15441538 DAPK3 coding downstream 42410 15434879 ~ 15441538 (-)
CI01000004_15429682_15430354 NA coding downstream 52899 15428518 ~ 15431049 (-)
CI01000004_15416876_15425066 NA coding downstream 58784 15416876 ~ 15425164 (-)
CI01000004_15370117_15389832 PRKCI coding downstream 94116 15369754 ~ 15389832 (-)
CI01000004_15561061_15573201 HIAT1A, MFSD14A coding upstream 21750 15559909 ~ 15573201 (-)
CI01000004_15581505_15586825 NA coding upstream 43231 15581390 ~ 15586825 (-)
CI01000004_15653837_15673610 NFATC4 coding upstream 115566 15653725 ~ 15673610 (-)
CI01000004_15702447_15708692 METTL17 coding upstream 164212 15702371 ~ 15708692 (-)
CI01000004_15726420_15733105 NA coding upstream 187893 15726052 ~ 15733105 (-)
G34734 NA non-coding downstream 85171 15398571 ~ 15398777 (-)
G34733 NA non-coding downstream 85940 15397806 ~ 15398008 (-)
G34634 NA non-coding downstream 165726 15316241 ~ 15318222 (-)
G34611 NA non-coding downstream 191283 15286323 ~ 15292665 (-)
G34717 NA non-coding downstream 203806 15279943 ~ 15280142 (-)
G34768 NA non-coding upstream 138413 15676572 ~ 15682517 (-)
G34613 NA non-coding upstream 154931 15693090 ~ 15694289 (-)
G34595 NA non-coding upstream 158846 15697005 ~ 15700776 (-)
G34640 NA non-coding upstream 210490 15748649 ~ 15748929 (-)
G34608 NA non-coding upstream 225083 15763242 ~ 15765773 (-)
G34718 NA other downstream 202299 15281016 ~ 15281649 (-)
CI01000004_15086759_15087492 NA other downstream 393590 15086671 ~ 15087575 (-)
G34668 NA other downstream 431173 15051176 ~ 15052775 (-)
G34632 NA other downstream 458727 15011361 ~ 15025221 (-)
CI01000004_14827536_14831360 NA other downstream 655825 14827496 ~ 14831526 (-)
G34633 NA other upstream 249227 15787386 ~ 15787897 (-)
CI01000004_15832789_15836192 NA other upstream 294414 15832573 ~ 15836231 (-)
G34796 NA other upstream 322454 15860613 ~ 15863748 (-)
G34934 NA other upstream 863586 16401745 ~ 16421506 (-)
G34982 NA other upstream 964566 16502725 ~ 16515974 (-)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location