hmgcra (hmgcra,LOC107720287,LOC107699716,LOC107756298,LOC107587518,LOC107703249,LOC107555490)


Basic Information

Item Value
gene id hmgcra
gene name hmgcra,LOC107720287,LOC107699716,LOC107756298,LOC107587518,LOC107703249,LOC107555490
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056703.1
NCBI id CM032072.1
chromosome length 32833783
location 18869042 ~ 18877023 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043238778.1
GGAGAATGCCGGTTTTGGCGACCGGAGTCCTCAAACGTCAGGATATGGATTAATGTCGTCTGTAGTTATTTAATTCGGCCGCTCCAATCATGAAAAACGCACCTAAATGCTAATTTATAACAGCGAAAACATCTATAGGTTATAGGTAAATCAGCCGCATATGTGGAGGATTTTACAGTGATTTGCTGTTGGTGTACTAATTCTTTAACCCTCGTTGACCCTTACTGTAAGTGACTGTAACACACCTTCAAAATGCTGACGAGACTTTTCCGAATCCACGGCCTGTTTGTGGCCTCCCATCCTTGGGAAGTCATTGTGGCTACTGTCACTCTCACCATCTGCATGATGTCCATGAATATGTTCACTGGAAATAACCAAATTTGTGGCTGGAACTTTGATTGCCCCAAATTGGAAGAGCAAATCTTAAGCAGCGACATCATTATCCTGACAATCACAAGATGCATAGCAATAGTCTACATTTACTTTCAATTCCAAAATCTTCGACAGTTAGGATCCAAATACATATTGGgCATAGCAGGACTGTTCACAATATTCTCCAGTTTTGTGTTTAGCACAGTCGTAATTCACTTCCTGGACAAGGAGCTTACAGGCCTCAATGAGGCTTTACCGTTCTTTCTGCTGTTGATTGATCTCTCCAAAGCATGCGCTCTGGCTAAGTTTGCCTTGAGTTCAAACTCACAGGATGAGGTGAGGGAAAATATTGCCAAAGGAATGGCCGTTTTAGGACCCACTTTTACTCTTGATGCCCTTGTGGAGTGCCTGGTGATCGGTGTGGGAACAATGTCAGgTGTGCGACAGCTCGAGATCATGTGCTGCTTCGGTTGCATGTCTGTATTGGCTAACTACTTTGTGTTCATGACCTTCTTCCCGGCCTGTGTCTCTCTTGTGCTGGAGTTGTCCAGAGAGAGCAGGGAGGGACGGCCCATCTGGCAGCTGAGTCACTTTGCTAGAGTtctggaggaggaagaggacaaCAAGCCTAACCCTGTCACACAAAGAGTCAAAATGATCATGTCTCTTGGCCTGGTCATGGTTCACGCTCATAGCCGGTGGATTGCAGATCCCACATCAAGTAATGGAACTCTTGATCTTCCTCAAGTTGGAGTGAGCCTGAATGAAAATATGCCCAAAAGAATTGAGCCAGACATGCCCCTTTGGCACTTTTACCTGTCCAGgaTGATCAGCATGGACATTGAGCAGGTGATCACACTGGGTCTTGCTCTGTTCCTGGCTGTGAAGTACATTTTCTTCGAGCAGGTGGAGATGGAGTCTACCCTGTCCCTGAAAGTCCCCACTCCTAGCTCCATGCTCTCTCAGAAATGGTCTCCTGATCAGTGCTGCAGGAAAGAGGTTCCCGTTTCCAGCAAGCCGGAGAAAACTCCCCCTTCCCCTCCAGTTGTTACCAAAGAAGAAAGAGGTTTGCTCTTCTTACCTTTACTCATTTGTGTTAGCTTTTTGTCAGTGGAATCTAACTTCAGTGTCTTTCTTTCAGATTTAGTCATTCGTCCCCTGCCTGCCCCTGAGCCTGAGCATAAAAGTACTTTTGTTTTGGGAGAGGATGAAACTCAGGAAATTGTCGATGCGTCGGAGAGCGTGATCAGTGTTCCTGCTGAACCCAGACCTGTGGAAGACTGTCTGTCCATTCTGAAAAACCCAGATATGGGCGCGCGCTACCTCAGCGATGAAGAGGTGATCGTGTTGGTGAACTCAAAGCACATCCCAGCTTACAAATTGGAGGCCATGATGGAAACCCCTGAACGGGGGGTGATGATCCGTAGAAAAATGCTCAGCCCCAAATTCCCAGAGCCCACAGCTCTCACCTGTCTGCCTTATAAAGACTATGACTACTCTAAGGTGATGGGAACATGTTGTGAGAACGTCATCGGTTACATGCCAGTTCCTGTGGGGGTTGCTGGCCCTCTGTTATTGGACGGAAAGCAGTTTCAGGTCCCCATGGCAACAACTGAGGGCTGCCTGGTTGCCAGCACAAATAGAGGCTGCAGAGCTATTGCATTGGCAGGAGGTGCCAATAGCCGTGTTCTTGCAGATGGAATGACCAGAGGGCCGGTGGTACGTCTGCCCTCTGCCTGTCAGGCAGCTGAAGTCAAGGCCTGGCTGGAAAGCGATGAAGGCTTCGGGAGCATCAAAGAGGCCTTTGACCAGACCAGCAGGTTCGCACGATTGGAGaagcttctgattggcctggCGAGTCGCAATCTATACATTCGGTTCCAGTCCAGGACTGGAGACGCAATGGGGATGAACATGATCTCAAAAGGAACAGAACAGGCTCTTGCCAGGCTGAAGGAGGAGTTTCCAGAGCTTCAGATTTTGGCTGTTAGTGGAAACTACTGCACTGACAAAAAACCTGCCGCCATCAACTGGATCGAGGGCAGGGGCAAGTCAGTGGTGTGTGAGACCACCGTCCCAGCCAAAGTCGTCAAAGAGattttaaAGACGTCTACTGAGGCTCTGGTAGATGTCAACATCAGCAAGAACTTGGTTGGGTCTGCTATGGCTGGAAGCATCGGAGGTTACAACGCTCACGCCGCCAACATCGTAGCTGCTATCTATATCGCTTGTGGACAGGACCCAGCACAGACGGTGGGCAGCTCTAATTGTATCACTATTATGGAAGCCTCAGGCCCCACCGGGGAGGATCTTTATATCAGCTGTACTATGCCCTCCATTGAGCTGGGCACTGTGGGCGGAGGCACTAACCTTCCTCCTCAGCAAGCTTGTTTACAGATGTTAGGCGTGCTGGGCGCCAGTCAGGAGTGCCCGGGTGAAAATGCCCGACAGCTTGCCAAGGTGGTGTGTGGTACCGTACTTGCCGGAGAGCTGTCACTCATGTCTGCACTCGCTGCAGGACACCTGGTCAAAAGTCACATGACTCACAACAGaTCAAAAGTGAATTTGCAAGAAGCTCCAGGAACATGCACTAAGCAGGCATCTTGAGACGTCGCCTGCTGAAGATGCAAAAGGCACATAAAGAAGGAGGATCTCAAGTTTAAAGGCAAATGTGATTAGTAATTTAGATTATGTTAAAGACCAGCAAAAGGAATACAGACGTAAGACTGGTCCCCTGATCTGTTAAAAGGAGTTGTCTTGTAACTACAGGCATTCTTTCAAAGAAATCCGGTTGCAATCAAAGACTGGAATCAGGACCTGCTGCGTTCACACAAGCCTAGAGCCAGTATTTCTAAATCATATCTGAGCAGAAATAGCTGCTTCTGGACCTGCTTTGTTAAGCTTAACTTGCTATGGAGAGCAAAGCAAATCTCAAGTTTCACTGCGGCCAGCGCATAGAGAAACAGAAAGCCACGTAATTTAACTTATTTCTTAAATTCAGTATAGTTCAGATCACATACATGACTGACTGGATGgggttttatttcattatctgTTGGGGATAGCAACAGGGATCATATCGTTGCCAACTTTTTGCCAACTGGAAACAGCAACATTAGACAGAAAGGGAAGGATAAAGTTTACTCTTCATTGCACTTATTAAGGGAAATGGCATAGAGCAGTACTGATACAAAGAGGAATATAAAGTACTATGATTCACTAGTTAATACACACGTAGAATATTACAGAACGACTCTGAAATTGCCAAATGCAGCCGTCAGCAGTGCTTGCTATGTTTTCCGTGTCAGAAtgtacattgatttttttttttttttttttgctatgacACAGGAAATGAATGACTTTTGTAATTAAAAGGGTTGTGCTGTGGCACGACGGATATACAAAAATTTCAAAAGGTGCTACGATCCACACAATGTTTCAGTTCTTTGTAAATTTAGCtatttctttgtgtttaaaCACCTCTAATAATGGGTTCATGTAACAACACTTAACTTAACGCCTTGCATGTTTCCGAAGGCTTGAAACGGCTTTTATTTATATGGTTCTGGTTTTTGTGTCATGGAAAAGAGTGGCTGTTTAGACATGTACGTTTCATGCTGAAGACATTGAAAGGAAGCTTTGTTCTTTGTCCCCCCCCCAAAGGCTCAATTCAAATTCtccaataaataataaactgcaaacgttttgtatatttttttataataaaaagaaaatgtagaatTCATTGA
>XM_043238780.1
GGAGAATGCCGGTTTTGGCGACCGGAGTCCTCAAACGTCAGGATATGGATTAATGTCGTCTGTAGTTATTTAATTCGGCCGCTCCAATCATGAAAAACGCACCTAAATGCTAATTTATAACAGCGAAAACATCTATAGGTTATAGGTAAATCAGCCGCATATGTGGAGGATTTTACAGTGATTTGCTGTTGGTGTACTAATTCTTTAACCCTCGTTGACCCTTACTGTAAGTGACTGTAACACACCTTCAAAATGCTGACGAGACTTTTCCGAATCCACGGCCTGTTTGTGGCCTCCCATCCTTGGGAAGTCATTGTGGCTACTGTCACTCTCACCATCTGCATGATGTCCATGAATATGTTCACTGGAAATAACCAAATTTGTGGCTGGAACTTTGATTGCCCCAAATTGGAAGAGCAAATCTTAAGCAGCGACATCATTATCCTGACAATCACAAGATGCATAGCAATAGTCTACATTTACTTTCAATTCCAAAATCTTCGACAGTTAGGATCCAAATACATATTGGgCATAGCAGGACTGTTCACAATATTCTCCAGTTTTGTGTTTAGCACAGTCGTAATTCACTTCCTGGACAAGGAGCTTACAGGCCTCAATGAGGCTTTACCGTTCTTTCTGCTGTTGATTGATCTCTCCAAAGCATGCGCTCTGGCTAAGTTTGCCTTGAGTTCAAACTCACAGGATGAGGTGAGGGAAAATATTGCCAAAGGAATGGCCGTTTTAGGACCCACTTTTACTCTTGATGCCCTTGTGGAGTGCCTGGTGATCGGTGTGGGAACAATGTCAGgTGTGCGACAGCTCGAGATCATGTGCTGCTTCGGTTGCATGTCTGTATTGGCTAACTACTTTGTGTTCATGACCTTCTTCCCGGCCTGTGTCTCTCTTGTGCTGGAGTTGTCCAGAGAGAGCAGGGAGGGACGGCCCATCTGGCAGCTGAGTCACTTTGCTAGAGTtctggaggaggaagaggacaaCAAGCCTAACCCTGTCACACAAAGAGTCAAAATGATCATGTCTCTTGGCCTGGTCATGGTTCACGCTCATAGCCGGTGGATTGCAGATCCCACATCAAGTAATGGAACTCTTGATCTTCCTCAAGTTGGAGTGAGCCTGAATGAAAATATGCCCAAAAGAATTGAGCCAGACATGCCCCTTTGGCACTTTTACCTGTCCAGgaTGATCAGCATGGACATTGAGCAGGTGATCACACTGGGTCTTGCTCTGTTCCTGGCTGTGAAGTACATTTTCTTCGAGCAGGTGGAGATGGAGTCTACCCTGTCCCTGAAAGTCCCCACTCCTAGCTCCATGCTCTCTCAGAAATGGTCTCCTGATCAGTGCTGCAGGAAAGAGGTTCCCGTTTCCAGCAAGCCGGAGAAAACTCCCCCTTCCCCTCCAGTTGTTACCAAAGAAGAAAGAGATTTAGTCATTCGTCCCCTGCCTGCCCCTGAGCCTGAGCATAAAAGTACTTTTGTTTTGGGAGAGGATGAAACTCAGGAAATTGTCGATGCGTCGGAGAGCGTGATCAGTGTTCCTGCTGAACCCAGACCTGTGGAAGACTGTCTGTCCATTCTGAAAAACCCAGATATGGGCGCGCGCTACCTCAGCGATGAAGAGGTGATCGTGTTGGTGAACTCAAAGCACATCCCAGCTTACAAATTGGAGGCCATGATGGAAACCCCTGAACGGGGGGTGATGATCCGTAGAAAAATGCTCAGCCCCAAATTCCCAGAGCCCACAGCTCTCACCTGTCTGCCTTATAAAGACTATGACTACTCTAAGGTGATGGGAACATGTTGTGAGAACGTCATCGGTTACATGCCAGTTCCTGTGGGGGTTGCTGGCCCTCTGTTATTGGACGGAAAGCAGTTTCAGGTCCCCATGGCAACAACTGAGGGCTGCCTGGTTGCCAGCACAAATAGAGGCTGCAGAGCTATTGCATTGGCAGGAGGTGCCAATAGCCGTGTTCTTGCAGATGGAATGACCAGAGGGCCGGTGGTACGTCTGCCCTCTGCCTGTCAGGCAGCTGAAGTCAAGGCCTGGCTGGAAAGCGATGAAGGCTTCGGGAGCATCAAAGAGGCCTTTGACCAGACCAGCAGGTTCGCACGATTGGAGaagcttctgattggcctggCGAGTCGCAATCTATACATTCGGTTCCAGTCCAGGACTGGAGACGCAATGGGGATGAACATGATCTCAAAAGGAACAGAACAGGCTCTTGCCAGGCTGAAGGAGGAGTTTCCAGAGCTTCAGATTTTGGCTGTTAGTGGAAACTACTGCACTGACAAAAAACCTGCCGCCATCAACTGGATCGAGGGCAGGGGCAAGTCAGTGGTGTGTGAGACCACCGTCCCAGCCAAAGTCGTCAAAGAGattttaaAGACGTCTACTGAGGCTCTGGTAGATGTCAACATCAGCAAGAACTTGGTTGGGTCTGCTATGGCTGGAAGCATCGGAGGTTACAACGCTCACGCCGCCAACATCGTAGCTGCTATCTATATCGCTTGTGGACAGGACCCAGCACAGACGGTGGGCAGCTCTAATTGTATCACTATTATGGAAGCCTCAGGCCCCACCGGGGAGGATCTTTATATCAGCTGTACTATGCCCTCCATTGAGCTGGGCACTGTGGGCGGAGGCACTAACCTTCCTCCTCAGCAAGCTTGTTTACAGATGTTAGGCGTGCTGGGCGCCAGTCAGGAGTGCCCGGGTGAAAATGCCCGACAGCTTGCCAAGGTGGTGTGTGGTACCGTACTTGCCGGAGAGCTGTCACTCATGTCTGCACTCGCTGCAGGACACCTGGTCAAAAGTCACATGACTCACAACAGaTCAAAAGTGAATTTGCAAGAAGCTCCAGGAACATGCACTAAGCAGGCATCTTGAGACGTCGCCTGCTGAAGATGCAAAAGGCACATAAAGAAGGAGGATCTCAAGTTTAAAGGCAAATGTGATTAGTAATTTAGATTATGTTAAAGACCAGCAAAAGGAATACAGACGTAAGACTGGTCCCCTGATCTGTTAAAAGGAGTTGTCTTGTAACTACAGGCATTCTTTCAAAGAAATCCGGTTGCAATCAAAGACTGGAATCAGGACCTGCTGCGTTCACACAAGCCTAGAGCCAGTATTTCTAAATCATATCTGAGCAGAAATAGCTGCTTCTGGACCTGCTTTGTTAAGCTTAACTTGCTATGGAGAGCAAAGCAAATCTCAAGTTTCACTGCGGCCAGCGCATAGAGAAACAGAAAGCCACGTAATTTAACTTATTTCTTAAATTCAGTATAGTTCAGATCACATACATGACTGACTGGATGgggttttatttcattatctgTTGGGGATAGCAACAGGGATCATATCGTTGCCAACTTTTTGCCAACTGGAAACAGCAACATTAGACAGAAAGGGAAGGATAAAGTTTACTCTTCATTGCACTTATTAAGGGAAATGGCATAGAGCAGTACTGATACAAAGAGGAATATAAAGTACTATGATTCACTAGTTAATACACACGTAGAATATTACAGAACGACTCTGAAATTGCCAAATGCAGCCGTCAGCAGTGCTTGCTATGTTTTCCGTGTCAGAAtgtacattgatttttttttttttttttttgctatgacACAGGAAATGAATGACTTTTGTAATTAAAAGGGTTGTGCTGTGGCACGACGGATATACAAAAATTTCAAAAGGTGCTACGATCCACACAATGTTTCAGTTCTTTGTAAATTTAGCtatttctttgtgtttaaaCACCTCTAATAATGGGTTCATGTAACAACACTTAACTTAACGCCTTGCATGTTTCCGAAGGCTTGAAACGGCTTTTATTTATATGGTTCTGGTTTTTGTGTCATGGAAAAGAGTGGCTGTTTAGACATGTACGTTTCATGCTGAAGACATTGAAAGGAAGCTTTGTTCTTTGTCCCCCCCCCAAAGGCTCAATTCAAATTCtccaataaataataaactgcaaacgttttgtatatttttttataataaaaagaaaatgtagaatTCATTGA

Function

symbol description
hmgcra Predicted to enable hydroxymethylglutaryl-CoA reductase (NADPH) activity. Acts upstream of or within skeletal muscle tissue development. Predicted to be located in endoplasmic reticulum; membrane; and peroxisome. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum membrane and peroxisomal membrane. Is expressed in gut and liver. Human ortholog(s) of this gene implicated in several diseases, including asthma; coronary artery disease (multiple); dementia; diabetes mellitus (multiple); and neurodegenerative disease (multiple). Orthologous to human HMGCR (3-hydroxy-3-methylglutaryl-CoA reductase).

NR:

description
3-hydroxy-3-methylglutaryl-coenzyme A reductase

GO:

id name namespace
GO:0007517 muscle organ development biological_process
GO:0015936 coenzyme A metabolic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0008299 isoprenoid biosynthetic process biological_process
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0050661 NADP binding molecular_function
GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity molecular_function

KEGG:

id description
K00021 HMGCR; hydroxymethylglutaryl-CoA reductase (NADPH)

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043238778.1 True 4124 mRNA 0.46 19 18869042 18877023
XM_043238780.1 False 4049 mRNA 0.46 20 18869042 18877023

Neighbor

gene id symbol gene type direction distance location
ttc37 ttc37,LOC107720289,LOC107756296,LOC107703247 coding downstream 36529 18815078 ~ 18832513 (-)
mctp1a mctp1a,mctp1,LOC107756292,LOC107720291,LOC107703246,LOC107587547 coding downstream 63180 18678708 ~ 18805862 (-)
kiaa0825 kiaa0825,LOC107720295,LOC107699712,LOC107587549,LOC107756295,LOC107703244 coding downstream 220364 18535605 ~ 18648678 (-)
fam172a fam172a,LOC107720296,LOC107703201,LOC107756291 coding downstream 334535 18385973 ~ 18534507 (-)
LOC122345814 LOC107567414,LOC107756269,LOC107699689,LOC107575123,LOC107720179,LOC107720216 coding downstream 822655 18043514 ~ 18046387 (-)
ccdc180 ccdc180,LOC107587542,LOC107579191 coding upstream 44404 18921427 ~ 18932581 (-)
card9 LOC107699720,LOC107756300,LOC107555475 coding upstream 55677 18932700 ~ 18937965 (-)
snapc4 LOC107699680,LOC107720210 coding upstream 61299 18938322 ~ 18949359 (-)
entr1 LOC107720284,LOC107699695,LOC107587560,LOC107555476,LOC107703226 coding upstream 72539 18949562 ~ 18952735 (-)
otpb otpb,otp,LOC107720233,LOC107587559,LOC107555478,LOC108423578 coding upstream 202720 19079743 ~ 19083078 (-)
G37637 NA non-coding downstream 55271 18813564 ~ 18813771 (-)
G37571 NA non-coding downstream 477394 18373317 ~ 18391648 (-)
G37570 NA non-coding downstream 495792 18372208 ~ 18373250 (-)
G37569 NA non-coding downstream 498225 18370523 ~ 18370817 (-)
G37565 nr2f1a,nr2f1,LOC107671052,LOC107567418 non-coding downstream 503575 18362413 ~ 18365467 (-)
G37757 ckmt2b,ckmt2,LOC107720280,LOC107756255 non-coding upstream 191891 19068914 ~ 19075774 (-)
G37774 NA non-coding upstream 246002 19123025 ~ 19123308 (-)
G37776 NA non-coding upstream 255790 19132813 ~ 19133144 (-)
G37792 NA non-coding upstream 347329 19224352 ~ 19225429 (-)
G37799 NA non-coding upstream 404842 19281865 ~ 19282092 (-)
LOC122344738 acsl1b,LOC107571490,LOC107678619,LOC107758469,LOC107552354,LOC108274927 other downstream 1518662 17346469 ~ 17350380 (-)
LOC122345693 NA other downstream 2009111 16787809 ~ 16859931 (-)
G37277 ncam1a,LOC107681081,LOC107548183,LOC107756101 other downstream 2155875 16687260 ~ 16713167 (-)
G37258 ncor2,LOC107687981,LOC107684513,LOC107753125 other downstream 2235921 16596855 ~ 16633121 (-)
LOC122344728 uprt,LOC107733222,LOC107672530,LOC107680369,LOC107748634 other downstream 2490527 16376266 ~ 16378515 (-)
mtx3 cmya5,mtx3,LOC107699728,LOC107703257,LOC107720274,LOC107756304,LOC107555495,LOC107756305,LOC107720223,LOC107703259 other upstream 298440 19175463 ~ 19183978 (-)
kcnt1b LOC107720246,LOC107699766,LOC107672542 other upstream 987996 19865019 ~ 19935576 (-)
G38058 NA other upstream 1174636 20051659 ~ 20055798 (-)
G38140 si:ch211-236k19.4,LOC107552622,LOC107740829,LOC107699705,LOC107731026,LOC107672535,LOC107587659 other upstream 1248566 20125589 ~ 20127390 (-)
LOC122345844 ppil3 other upstream 1517708 20394731 ~ 20396734 (-)

Expression


Co-expression Network