XLOC_000007 (f7)


Basic Information

Item Value
gene id XLOC_000007
gene name f7
gene type coding
species zebrafish (Danio rerio)
category of species model fish

Chromosome Information

Item Value
chromosome id NC_007112.7
NCBI id CM002885.2
chromosome length 59578282
location 119960 ~ 125246 (+)
genome version GRCz11_2017_zebrafish_Genome

Sequence

>TCONS_00000019
GTAAAGCGCAGTAAATATGAGTCTGCTGCTTGTGTTTTCTCTGCTCTCGAGTCTCCATTACTGCCATTCAGCAGCAGTGTTCGTGCACAGAGATGAAGCTCACGAGGTGTTGATCAGGAGCAAACGAGCCAACTCAGGCTGGTTTGAGGAGCTGAAGACGGGGAATCTGGAGCGCGAGTGTCTGGAGGAGAAATGCTCGTATGAGGAGGCGCGCGAGGTGTTCGAGCACACAGAGGCCACGAATGAGTTCTGGAAGATCTACGATGTTAAAGATCACTGCGCATCCAGTCCATGTGAGCATGACGGCCTCTGCACCACACAGAACGCGGACTcctacatgtgtttgtgtgcgccgGGCTTCAGCGGACGCCACTGTGAGCAATCGATTGGAGACGTTACCGACTCCTGTCTGCATGATAACGGCGGCTGCGAACACTTCTGCACGGAGCAGGACGGATGGAGAAACTGCTCCTGCGCAGACGGCTATTACCTAGATAACGGCGGGCAGAAGTGCCGGAGTCACGaggtgTTTCCGTGTGGGAAGGTTCCTCTCCTGCAGGCTGGAAAAGCTGCGGATCATCAGGTGGATCTCAGATCTCGTATCGTTGGAGGATCTGAATGTCCTAAAGGTCACTGTCCGTGGCAGgtgctgcTGAAGTACGGTGAGAAGGGTTTCTGTGGAGGTGTGATCTACAAGCCCACCTGGATCCTCACAGCTGCTCACTGCTTGGAAAAGCTCAAGGTCAAGTTCCTCAGGATAGTGGCAGgtgagcATGATCTGGAGGTGGACGAAGGCACGGAGCAGCTCATCCAGGTGGATCAGATGTTCACACACCCTGCGTACGTGTCTGAGACAGCGGACAGTGACATCGCCCTGCTGCGTCTGCGCACCCCCATCGTCTACAGTGTGTATGCGGTGCCGGTGTGTTTGCCGCTGCGGGAGATGGCGGAGCGCGAGCTGTGGGCGGTCAGCAAACACACGGTGAGCGGCTGGGGCAAACGCAGCGAGGACGGGCCGACCTCTCGTCTGCTGCGCCGGCTGCTGGTGCCGCGCATCCGCACGCAGGAGTGTGTGCAGGTCAGCAACCTCACGCTCACCAGCAACATGTTCTGCGCCGGATACATCGAGGGCCGGCAGGACTCCTGTAAGGGTGACAGCGGCGGCCCGCTGGTGACCCGGTACCGAGACACCGCCTTCCTACTGGGCATCGTGAGCTGGGGGAAAGGCTGCGCTCGCCCGGGCTCCTACGGCATCTACACACGCGTCTCCAACTACCTGCAGTGGATCCGACAAACAACCAACACCACGATACACTGATGAAGACATGACCCATGTGCATATCTCATCAAGATTGCTACTCTTAGGTGAACAATTAACAAATATTAACTATTATAGTTAATGTTTGTTAAAAATAGCACaattatattgaaaataaaaaatatttatattaattatgaagACGGTGTTATAGCCCAAAATACCCAATAGTTGAGCATCAGCTGCTTTCCTGAGATCCTGTACATATTAGACTCAGATCTGATATTTTGCGCAGGTTATATTGCATTTTTAGCAGGTATTTAATGATTTTGCTCTGATTAATCAGGAGATGTGCAGCTCATTATCTCCATATTATTAATGCTCAACTGTAGTAAACACTCGCTTTACATAAATCCAAAACCAGCCAATAAATATCAGCGCATCCCTATTTAACGCTTGTGTTCATGTCTGATGATCTTCTGTTGTGTGTATTCTCTCAGTGGCTTGTCCATCACTGTCTCATTATCCAATAAATAATGCAGATGTGATTC

Function

symbol description
f7 Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Acts upstream of or within blood coagulation, fibrin clot formation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in blood plasma; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including acute pancreatitis; artery disease (multiple); diabetes mellitus (multiple); factor VII deficiency; and obesity. Orthologous to human F7 (coagulation factor VII).

GO:

id name namespace
GO:0072378 blood coagulation, fibrin clot formation biological_process
GO:0007596 blood coagulation biological_process
GO:0006508 proteolysis biological_process
GO:0005576 extracellular region cellular_component
GO:0005615 extracellular space cellular_component
GO:0005509 calcium ion binding molecular_function
GO:0004252 serine-type endopeptidase activity molecular_function
GO:0016787 hydrolase activity molecular_function
GO:0008233 peptidase activity molecular_function
GO:0008236 serine-type peptidase activity molecular_function

KEGG:

id description
ko04610 Complement and coagulation cascades
ko01002 Peptidases and inhibitors

ZFIN:

id description
ZDB-GENE-010814-1 Predicted to enable calcium ion binding activity and serine-type endopeptidase activity. Acts upstream of or within blood coagulation, fibrin clot formation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in blood plasma; liver; and yolk syncytial layer. Human ortholog(s) of this gene implicated in several diseases, including acute pancreatitis; artery disease (multiple); diabetes mellitus (multiple); factor VII deficiency; and obesity. Orthologous to human F7 (coagulation factor VII).

Ensembl:

ensembl_id ENSDARG00000034862

RNA

RNA id representative length rna type GC content exon number start site end site
TCONS_00000019 True 1809 mRNA 0.51 8 119960 125246

Neighbor

gene id symbol gene type direction distance location
XLOC_000006 f7l coding upstream 814 109798 ~ 119146 (+)
XLOC_000005 hikeshi coding upstream 80769 36552 ~ 39191 (+)
XLOC_000004 eed coding upstream 85630 27690 ~ 34330 (+)
XLOC_000003 CU651657.1 coding upstream 92705 25585 ~ 27255 (+)
XLOC_000002 nfkbiz coding upstream 96571 18716 ~ 23389 (+)
XLOC_000008 f7i coding downstream 2004 127250 ~ 134079 (+)
XLOC_000009 f10 coding downstream 10657 135903 ~ 142469 (+)
XLOC_000010 prozb coding downstream 19038 144284 ~ 151998 (+)
XLOC_000011 NA coding downstream 31546 156792 ~ 157282 (+)
XLOC_000012 cul4a coding downstream 32547 157793 ~ 167398 (+)
XLOC_000018 NA non-coding downstream 230235 355481 ~ 358562 (+)
XLOC_000024 dre-mir-155 non-coding downstream 451198 576444 ~ 576521 (+)
XLOC_000026 NA non-coding downstream 669730 794976 ~ 911551 (+)
XLOC_000028 NA non-coding downstream 890566 1015812 ~ 1033638 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
grasscarp (Ctenopharyngodon idella) CI01000299_06295715_06298755 F7 coding CI01000299 null 6295613 ~ 6298775 (-)