LOC122346795 (igfbp2,igfbp2a,LOC107688817,LOC107731775,LOC107719297,LOC107663074,LOC108438161)


Basic Information

Item Value
gene id LOC122346795
gene name igfbp2,igfbp2a,LOC107688817,LOC107731775,LOC107719297,LOC107663074,LOC108438161
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056704.1
NCBI id CM032073.1
chromosome length 27473687
location 7725403 ~ 7732324 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043241647.1
ATGATAGTGGAGCATTTGAAGGATGAAAGGATTTTATGGCAGCATGTCATCTTCACTGATCTGGAGTGCAGTGAGGTGCAGGACTCTTTTGACATTGGTCTGACTGAGGTTCCTCCTATAAGGAAGCCCACCAAAGACAGTCCATGGAAGGAGAGCGCTGTCCTTCAACACCGCCAGCAGCTAAAGACCAAGATGAAGTACAACAAAGTTGAGGACCCTAAAGCGCCACATGCCAAACAGaGCCAGTGTCAGCAGGAGCTTGACCAGGTCCTGGAAAGGATTGCAAAAATACCCTTCAGAGATAACAGGGGCCCCCTGGAGGACCTTTATTCCCTGCACATGCCCAACTGTGACAAGAGAGGGCAGTACAACCTGAAACAGtgtaagATGTCAGTGAATGGACATCGTGGTGAGTGCTGGTGTGTGAACCCGCACACAGGTAGACCCATCCCCACCTCTCCGCTGATAAGGGGGTGA

Function

symbol description
igfbp2a Enables insulin-like growth factor I binding activity and insulin-like growth factor II binding activity. Involved in negative regulation of DNA replication; negative regulation of developmental growth; and regulation of insulin-like growth factor receptor signaling pathway. Acts upstream of or within circulatory system development; negative regulation of cell population proliferation; and regulation of growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including brain; head; immature eye; testis; and yolk syncytial layer. Human ortholog(s) of this gene implicated in obesity. Orthologous to human IGFBP2 (insulin like growth factor binding protein 2).
igfbp2 Enables insulin-like growth factor I binding activity. Involved in positive regulation of activated T cell proliferation. Located in extracellular space. Implicated in obesity. Biomarker of Alzheimer's disease; Kuhnt-Junius degeneration; and obesity.

NR:

description
PREDICTED: insulin-like growth factor-binding protein 2-A

GO:

id name namespace
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway biological_process
GO:0007507 heart development biological_process
GO:0008156 negative regulation of DNA replication biological_process
GO:0001525 angiogenesis biological_process
GO:0001558 regulation of cell growth biological_process
GO:0008285 negative regulation of cell population proliferation biological_process
GO:0048640 negative regulation of developmental growth biological_process
GO:0040015 negative regulation of multicellular organism growth biological_process
GO:0005576 extracellular region cellular_component
GO:0031994 insulin-like growth factor I binding molecular_function
GO:0031995 insulin-like growth factor II binding molecular_function

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043241647.1 True 477 mRNA 0.51 4 7725403 7732324

Neighbor

gene id symbol gene type direction distance location
LOC122347094 tns1a,LOC107688818,LOC107709585,LOC107719294,LOC107562221,LOC107663075 coding downstream 30284 7661464 ~ 7695119 (-)
tns1a tns1a,LOC107688818,LOC107709585,LOC107663075,LOC107719294,LOC107586330 coding downstream 66203 7608473 ~ 7659200 (-)
LOC122346455 tns1a,LOC107688818,LOC107709585,LOC107562221,LOC107663075,LOC107586330,LOC107719294 coding downstream 337104 7385719 ~ 7388299 (-)
col18a1b LOC107709584,LOC107586328,LOC107688819 coding downstream 342598 7356348 ~ 7382805 (-)
LOC122347322 zgc:162999,LOC107586326,LOC107562228,LOC107688822,LOC108438154,LOC107709582,LOC107677632,LOC107719292 coding downstream 387515 7333023 ~ 7337888 (-)
LOC122347101 igfbp2,igfbp2a,LOC107731775,LOC107688817,LOC107719297,LOC107663074,LOC108438161 coding upstream 233424 7965748 ~ 7980089 (-)
inha inha,LOC107731770,LOC107688903,LOC107719299,LOC107694906,LOC107569459,LOC107586362 coding upstream 280801 8013125 ~ 8015759 (-)
cacng1a cacng1a,cacng1,LOC107586374,LOC107688902,LOC107716892,LOC107569457 coding upstream 450691 8183015 ~ 8188384 (-)
cacng4a LOC107688901,LOC107586376,LOC107716888 coding upstream 466787 8199111 ~ 8202841 (-)
psmd12 psmd12,LOC107688808,LOC107694910 coding upstream 470655 8202979 ~ 8206792 (-)
G43478 NA non-coding downstream 226968 7461191 ~ 7498435 (-)
G43472 NA non-coding downstream 294957 7429778 ~ 7430446 (-)
G43251 NA non-coding downstream 902382 6815260 ~ 6823021 (-)
G43161 NA non-coding downstream 1242010 5995956 ~ 6483393 (-)
G43516 NA non-coding upstream 65800 7798124 ~ 7799697 (-)
G43528 NA non-coding upstream 124141 7856465 ~ 7857596 (-)
G43513 LOC107688815 non-coding upstream 317073 8049397 ~ 8050678 (-)
G43660 NA non-coding upstream 450355 8182679 ~ 8182882 (-)
G43691 NA non-coding upstream 561730 8294054 ~ 8294286 (-)
G43463 nomo,LOC107677623,LOC107562229,LOC107709581,LOC107733372,LOC107688882 other downstream 139036 7579895 ~ 7586367 (-)
nomo nomo,LOC107677623,LOC107562229,LOC107709581,LOC107733372,LOC107688882,LOC107586361 other downstream 395838 7316947 ~ 7329565 (-)
LOC122346787 unc80,LOC107733373,LOC107677624,LOC107688825 other downstream 410629 7274840 ~ 7314774 (-)
agap1 agap1,LOC107688827,LOC107709574,LOC107677621,LOC107748916,LOC107586321,LOC103044997 other downstream 480224 7108162 ~ 7245179 (-)
trim63a trim63a,murf1,LOC107586317,LOC105896535 other downstream 697976 7001115 ~ 7027427 (-)
LOC122346476 cidec,LOC107731779,LOC107688813,LOC107694911,LOC107710160 other upstream 4766 7737090 ~ 7770451 (-)
G43514 spega,LOC107731772,LOC107688815,LOC107586363,LOC107719300 other upstream 314778 8047102 ~ 8048008 (-)
G43801 pick1,LOC107734822,LOC107734770,LOC107572282 other upstream 976382 8708706 ~ 8713858 (-)
G43890 NA other upstream 1528292 9260616 ~ 9261245 (-)
G43896 NA other upstream 1533678 9266002 ~ 9267324 (-)

Expression


Co-expression Network