gfi1ab (gfi1,gfi1ab,LOC107659005,LOC107590681,LOC107692343,LOC107566482)



Basic Information


Item Value
gene id gfi1ab
gene name gfi1,gfi1ab,LOC107659005,LOC107590681,LOC107692343,LOC107566482
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_056704.1
NCBI id CM032073.1
chromosome length 27473687
location 13489950 ~ 13495596 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence


>XM_043242777.1
ATAACGTTCAGGAAGCTTTTTGTCTCTTACGCGTAAAACCCATGAGATGAGATGGGCTGCGCGCTCTTCTCCTCGAACTAAACCCCGAGCGTCCTGCCTTCATCTCACAGCGAGCCCTGCGATCAGAGATAAAAAAGCCGCCGCATCCGTGGATCTGACAGATTGCTTGATCTTCACTAATGACTCAGGACACAACAGGAAGGAACCAGAGGAGACACAATGCCTAGGTCTTTCTTGGTGAAGAGCAAAAAAGCGCACAGCTACCACCAGCCCCGATCTTTGGAGGATGACTACAGCAGGCTTGATACTATTTTAGCTCACATATGTGCAGAAAGCAAAACTTCAGAGGAGTCGGATGCCCTGCCGGGAGACACTGCTGGCGCTTGTTCGCCGGACTCTCAGCTGGTGGATCAAGCTGATCTTTCTTCCAAGTCTCCTCTCAGCTGCGGGGGAAGCGTGTGCGACCGCTCCTCGGATTACGAAGACTTCTGGCGACCTCCATCACCATCAGCATCACCTGagtcAGAAAAGTCCTTTTCGCCCTCCGCTGAGGAAACGCAGCCATTCGCCGTCCCCTTCAGGCCTTACGCGTGGAGCAGGTACTCTGGATGTGAAATCAGGCAGCTGGTACAGCATACTCTCAACCATCACCACTCTCTGGACCTCGAGCGACCCGCTCCTCCGGCCTACTACAATGACCGCGTGGTCGAGTCCTCGCTCTTCACCGAAAGGGGGTCCGGCGCGAGCATCTACAACAGTTACAGTCCCACCGCCACCCTGTTCGAGCGCGCCACCGCCTCTGCGCTTTACGATGACAGCAACATCCTGGGAAAAGGACCCGAGATGAAAGCCGGCTCCGACGCGATGTGTAGCCGCCTCCTGTTGAACGGCGCGTACAAATGCATCAAATGCAGCAAGGTGTTTTCTACTCCGCACGGCCTGGAAGTGCACGTCCGGAGGTCGCACAGCGGAACGAGGCCCTTCGCTTGCGACATCTGCGGGAAAACGTTTGGACACGCGGTCAGTCTGGAACAACACAGAGCCGTGCACTCACAAGAGAGAAGCTTCGATTGTAAAATCTGCgggaaaagttttaaaaggtCGTCCACTCTGTCCACGCACCTCCTCATACACTCCGACACGCGGCCCTATCCGTGCCAGTACTGCGGGAAGAGGTTTCACCAGAAGTCAgacatgaagaaacacacgTTCATCCACACAGGGGAGAAGCCACACAAATGCCAGGTGTGTGGGAAAGCTTTCAGTCAGAGCTCCAATCTGATAACGCACAGCCGAAAACACACCGGATTCAAGCCGTTTGGATGTGACCTCTGCGGCAAAGGGTTCCAGCGCAAGGTCGATTTGAGAAGACACAAGGAAACACAGCACGGGCTGAAGTGAGGGGACGCTTCGGGACTTTACCAAACACTATCgggacttttttattttattttttttttaatttaacgaGCCGCAGATGCTCATTCATGAAacattaaatcagtgttttagaGTAGGCGACTAATAGCGTTTACATTAGCCGTAGAGCTGTTTATGCTCGGTGAGGTTTGCCTACGAGTCAGCGGCAGGCCAGCAGGTCTGGCAGCTTTCGAGGCGATGCTGTGCGGGGCATCACAGGGTATCTCCATCCAGATCAATAGCCCGCTGCAGAGACATGCCGGGCACCGTGTCTGAACCCAAAATATTATCACCAAAATAATCAGGGACGAAATATAACCGCCGCGAGAAAGGACACTGTATCACCCAAAATATCAGCTGAAGGAGAGAAAAATCACCGCATCTCAAAAGAATGCCACTTTGTTTTTCGAGGCTGCGGAGGGAATGCTGGCAAAACAAGCACTACAATAGACTGCGAGATTTCATCAATAAAAGGATTGTTTGTGTACTATAGCCTAAACTTATATGATCTGGCAACCTGTCGAAGTCTTTCcgttcatctttttttttttttccttttcgttTTCTTTAGCTTAGCCcgaataaacaaatacaactcAATTGTCTATACCTTTTCGAATAAATTTAAtcgctaaattaaattaaattaaatctgttttatatcatttacacTATTTATTGGAATAAAGAATTTTAAGGAGA

Function


symbol description
gfi1ab Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within peripheral nervous system development. Is expressed in anterior lateral mesoderm; nervous system; and ventral wall of dorsal aorta. Human ortholog(s) of this gene implicated in acute myeloid leukemia and severe congenital neutropenia 2. Orthologous to human GFI1 (growth factor independent 1 transcriptional repressor).
gfi1 Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and transcription cis-regulatory region binding activity. Involved in several processes, including cellular response to lipopolysaccharide; negative regulation of cellular biosynthetic process; and regulation of signal transduction. Located in nuclear body and nuclear matrix. Part of transcription repressor complex. Implicated in acute myeloid leukemia and severe congenital neutropenia 2. Biomarker of leukemia and myelodysplastic syndrome.

NR:

description
zinc finger protein Gfi-1-like

GO:

id name namespace
GO:0007422 peripheral nervous system development biological_process
GO:0003676 nucleic acid binding molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K09223 GFI1; growth factor independent 1

RNA


RNA id representative length rna type GC content exon number start site end site
XM_043242777.1 True 2121 mRNA 0.50 7 13489950 13495596

Neighbor


gene id symbol gene type direction distance location
glmnb glmnb,LOC107659021,LOC107692340,LOC107590673,LOC107731827 coding downstream 11039 13471896 ~ 13478911 (-)
trnaa-cgc_55 NA coding downstream 22011 13467868 ~ 13467939 (-)
trnaa-ugc_115 NA coding downstream 22385 13467494 ~ 13467565 (-)
trnaa-ugc_114 NA coding downstream 22724 13467155 ~ 13467226 (-)
trnaa-cgc_54 NA coding downstream 22893 13466986 ~ 13467057 (-)
evi5b evi5,LOC107590647,LOC107692341,LOC107566483 coding upstream 539 13496135 ~ 13535440 (-)
dipk1ab fam69a,fam69ab,LOC107590645,LOC107659006,LOC107566484 coding upstream 47611 13543207 ~ 13561025 (-)
zbtb11 zbtb11,LOC107731844,LOC107659025,LOC107590644,LOC107732022,LOC107692345,LOC107566487 coding upstream 66449 13562045 ~ 13569922 (-)
dpt dpt,LOC107659007,LOC107732012,LOC107590680,LOC107692436 coding upstream 83196 13578792 ~ 13585368 (-)
nme7 nme7,LOC107659027,LOC107731836,LOC107732015,LOC107692347,LOC107548663 coding upstream 111920 13607516 ~ 13638945 (-)
G44942 NA non-coding downstream 132429 13356987 ~ 13357521 (-)
G44941 NA non-coding downstream 135167 13354307 ~ 13354783 (-)
G44940 NA non-coding downstream 135770 13353915 ~ 13354180 (-)
G44939 NA non-coding downstream 136300 13353364 ~ 13353650 (-)
G44938 NA non-coding downstream 136881 13352462 ~ 13353069 (-)
G45014 NA non-coding upstream 41348 13536944 ~ 13611593 (-)
G45036 NA non-coding upstream 197742 13693338 ~ 13694164 (-)
G45039 NA non-coding upstream 201903 13697499 ~ 13697711 (-)
LOC122347350 NA non-coding upstream 328076 13823672 ~ 13835591 (-)
G45058 NA non-coding upstream 341709 13837305 ~ 13837538 (-)
LOC122347614 rab6ba,rab6b,LOC107696768,LOC107552273,LOC102207753,LOC100696791,LOC107694122,LOC103354239 other downstream 592232 12525756 ~ 12897718 (-)
brdt brdt,LOC107678354,LOC107749988,LOC107675431,LOC107730697,LOC107564432 other downstream 2420484 11055035 ~ 11069466 (-)
gng12b LOC107555383,LOC107678346,LOC107705318,LOC107564436,LOC105895117,LOC108271932 other downstream 2504818 10948692 ~ 10985132 (-)
ntn1a ntn1a,LOC107555375,LOC107704007,LOC107733905,LOC107569361,LOC107757426,LOC107660463,LOC105903456,LOC106587088,LOC105012279 other downstream 2654425 10578989 ~ 10835525 (-)
tmem131 tmem131,LOC107659030,LOC107692350,LOC107732007 other upstream 159664 13655260 ~ 13681294 (-)
pex5la pex5la,LOC107709207,LOC107590632,LOC107659033,LOC107692357,LOC107548659,LOC107732026 other upstream 222606 13718202 ~ 13785903 (-)
G45257 ttc22,LOC107590622,LOC107692368,LOC107659045,LOC107591163 other upstream 664879 14160475 ~ 14193166 (-)
LOC122347580 ttc4,LOC107738930,LOC107659046,LOC107709194,LOC107692369 other upstream 1831987 15327583 ~ 15330851 (-)
insl5a LOC107692440 other upstream 1993522 15489118 ~ 15490685 (-)

Expression



Co-expression Network