hsd17b4 (hsd17b4)


Basic Information

Item Value
gene id hsd17b4
gene name hsd17b4
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056706.1
NCBI id CM032075.1
chromosome length 24299999
location 1005559 ~ 1016565 (+)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043247205.1
GTGGGGCAAAAGTCACGGCGGAGCGTTTCGCGGCAGCTCTTCAGTGTTTTCTACAGAGTGACAAACATCACCTCAGTCACCAGGaactcacaaaacacacatcgTCTGAAGATGTCAGCGCCTTTGACTTTCGACGGCAGAGTCGTGCTGGTGACCGGAGCCGGAGGAGgttTGGGAAGGGAGTATGCTCTGGCGTTCGGTCAGAGAGGAGCCGCTGTCATCGTCAATGATCTGGGAGGAGATATTAAAGGAGGTGGCAGGAGCTCAGCGGCCGCTGATCAAGTGGTGGAGGAGATCAGGGCAAAAGGAGGCAAAGCCGTGGCTAACTACGATTCAGTGGAAGACGGAGAGAAGCTCATCCAGACCGCGCTGGACACGTTTGGCCGCATAGataTCGTGGTGAATAACGCTGGGATCCTGCGGGACCGATCGTTCTCCAGGACCAGTGACGTGGACTGGGACCTGATCCAGCGAGTGCACCTGAGAGGCTCGTTCCTCGTCACACGCGCCGCCTGGAACCACATGAAGAAGCAGAAGTTCGGGAGGGTCATCATGACGTCGTCGGCGGCGGGCATCTACGGAACCGGCCAGGCTAACTACAGCGCGGCCAAGCTGGGTCTGCTGGGGCTGTCCAACACGCTGGCCATCGAGGGACAGAAGTACAACATCCACTGCAACACGGTGGCCCCGACCGCTGGCTCCCGGCTGACCGAGACCGTCATGCCCCCAGATCTGGTGCAGTCTCTGAAGGCGGAGTACGTGGCTCCTCTGGTCCTCTGGCTCTGTCATGAAGCGTGTCAGGAGAACGGAGCGCTGTTCGAGGTCGGCGCCGGATGGATCGGGAAACTGCGCTGGGAGAGGAGTCTGGGACGCATCGTGAGGCAGAAGAACCGGAGCATGACGCCGGAGGACGTTCGAGACTCTTGGAGCCGGATCTGTGACTTCAGCGACGCCTCCAAACCCAGCAGCATCCAGgAGTCGCTGCAGACGCTGGTGGAGGTTCTGTCCAGAGTGGAAGAAGAACGTGAGATCGGAGCCAACCCGACCGGAGCATCCGCCGAAACAAACCCCTCGGTGGCCGTGGGACAGACGCTGCCGGAGATGAGCttctcttacacacacatgAACTGTATCCTGTACGCTCTGGGAGTGGGGATGTCCACCAGAGAGTCTGACCACCTCAGGTTCCTGTATGAAGGTCACCAGGACTTCAGCTGTCTGCCCACCTTCGGAGTGATTCCTGCCCAGAGCGCCATGATGGGCCTCGGCAGCGTCCCGGGCCTCGACATCGACTTCACCAGGctGCTGCATGGAGAGCAGTATCTGGAGATGTTCAGACCGATGCCCACCTCAGGGACTCTGACGTCTCGGGCCGCCGTGGCAGACGTTCTGGACAAAGGCTCAGGGATGGTCATCCTGCTGGACGtGCACACGTTCAGCGGCGGTCAGCCCGTGTGTTATAACCAGTTCTCGGTGTTCGTGGTCGGCTCCGGAGGATTCGGAGGGAAGCGGGCGTCCCAGAAGAGCGTGGCCACGGCTCCTCTTCCAGACAGAGCTCCAGACGCCGTGATCGTGGATCAGACCTCCAGAGATCAGgcggCTCTCTACAGACTCAGCGGTGACTGGAACCCGCTCCACATCGACCCCAGTTTCGCTGCGATGGGAGGGTTCAAGTCTCCCATCCTGCACGGCCTGTGTTCGTTGGGCTTCGCCGCTCGACACGTTCTGAAGCAGTACGCCGGAAACGACGTGTCCAGATTCAAGGCCATCAAGGTGCGTTTCGCCAAGCCCGTGTATCCGGGACAGTCTCTGCAGACGGAGATGTGGAAGGAAGCGAACAGAATTCACGTCCAGTGTAAGGTCAAGGAGTCGGGAGACGTGGTTCTGTCAGGAGCGTATATAGACTTACACTCAGAAGCGTCGGTGGGCCCCGGGCTGCCTCAGCCCGGCGGCGGCCTGCAGAGCGACCTGGTGTTCGCCGAGATCGAGCGCAGGATCAGAGACGACGGCGAGCAGCTGGTGAAGAAGGTCAAGGCCGTGTTCGGCTGGGAGATCAGCAAAGACGGCAGAACCGTCCGAGAGTGGACCATCGACCTGAAGACGGGCCGAGGATCTCTCCACAGAGGAGCTTCTGAAGCCGACGTGACCTTCAGCGTCTCAGACGAGGACTTCATGGAGGTGGTGATGGGAAAACTCAACCCTCAGAAGGCGTTCTTCGCCGGGAAGCTGAAAGTCAGAGGGAACGTCATGCTGAGCCAGAAGCTGGAGGCCGTTCTGAAGGACTACGCCAAGCTCTGAAGATCCAGATCCATCCCCGCTGACGAGAGCTCTGGAGAAAAACCCTGTCTTGTTTTCTCGTATAAATTCTTGAATCAAGATGTAAAAATGACTGATAGCTCTTCTTTTCTGAAAACAACAACCACATCGAGTtcgtttttgcttaaaacaagtaaaaatatctGCAGAGGGGGCAGGAAATAATAAGATATTAATACTAGTgctgattaattgcatttaaaataagtttgtttacataaatacagaggtgcatgtatatatatatatat

Function

symbol description
hsd17b4 Predicted to enable 17-beta-hydroxysteroid dehydrogenase (NAD+) activity; 3-hydroxyacyl-CoA dehydrogenase activity; and enoyl-CoA hydratase activity. Acts upstream of or within embryonic organ development and neuron development. Predicted to be active in peroxisome. Human ortholog(s) of this gene implicated in D-bifunctional protein deficiency; Perrault syndrome; and Stiff-Person syndrome. Orthologous to human HSD17B4 (hydroxysteroid 17-beta dehydrogenase 4).

NR:

description
peroxisomal multifunctional enzyme type 2

GO:

id name namespace
GO:0008152 metabolic process biological_process
GO:0016491 oxidoreductase activity molecular_function
GO:0032934 sterol binding molecular_function

KEGG:

id description
K12405 HSD17B4; (3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043247205.1 True 2567 mRNA 0.57 24 1005559 1016565

Neighbor

gene id symbol gene type direction distance location
LOC122351116 ppic,LOC107704600,LOC107713556,LOC107726227,LOC107566397,LOC100333141,LOC107703627 coding upstream 82351 918543 ~ 923208 (+)
LOC122351049 cep120,zgc:163014,LOC107726217,LOC107712640,LOC107694735 coding upstream 128612 853071 ~ 876947 (+)
LOC122350421 slc12a2,LOC107697601,LOC107712558,LOC108442001,LOC108265961,LOC107573338,LOC105890695,LOC107726215 coding upstream 163627 822359 ~ 841932 (+)
LOC122350422 NA coding upstream 184874 810039 ~ 820685 (+)
LOC122350088 NA coding upstream 203814 789181 ~ 801745 (+)
sema6a LOC107661172,LOC107663594 coding downstream 53276 1069841 ~ 1129502 (+)
cdo1 cdo1,LOC107729053,LOC107573765,LOC103396961 coding downstream 154084 1170649 ~ 1178671 (+)
tmed7 LOC107729055,LOC107728255,LOC107661170,LOC108265697,LOC107663596,LOC107572957,LOC107573769 coding downstream 169204 1185769 ~ 1187485 (+)
LOC122350615 fem1c,LOC107728259,LOC107572967,LOC106580179 coding downstream 171783 1188348 ~ 1199937 (+)
LOC122350068 ccdc112,LOC107573794,LOC107578772 coding downstream 187676 1204241 ~ 1209643 (+)
G59814 NA non-coding upstream 28853 973486 ~ 976706 (+)
G59824 NA non-coding upstream 45388 958679 ~ 960171 (+)
G59825 NA non-coding upstream 47328 957223 ~ 958231 (+)
G59811 NA non-coding upstream 54586 947677 ~ 950973 (+)
G59815 NA non-coding upstream 131360 873888 ~ 874199 (+)
G59845 LOC107698412,LOC107571775,LOC107726226,LOC100537613 non-coding downstream 4627 1021192 ~ 1022914 (+)
G59876 NA non-coding downstream 140357 1156922 ~ 1161160 (+)
G59877 NA non-coding downstream 145855 1162420 ~ 1164776 (+)
G59898 NA non-coding downstream 251619 1268184 ~ 1268392 (+)
G59899 NA non-coding downstream 251873 1268438 ~ 1268674 (+)
znf608 znf608,LOC107574328,LOC107697597,LOC107712568,LOC107704598,LOC107573349,LOC107726216 other upstream 153555 842077 ~ 852004 (+)
G59807 NA other upstream 200720 803653 ~ 804839 (+)
cdc14b cdc14b,LOC107661524,LOC107704583,LOC107568104,LOC107726879,LOC107570987 other upstream 454872 537775 ~ 550687 (+)
pggt1b pggt1b other downstream 194250 1210815 ~ 1218804 (+)
G60259 LOC107560031,LOC107559593,LOC108412499,LOC107754396 other downstream 898895 1915460 ~ 1918371 (+)
polb polb,LOC107670984,LOC107722860 other downstream 998294 2014859 ~ 2020034 (+)
LOC122350053 NA other downstream 1014259 2030824 ~ 2035980 (+)
LOC122350758 dynll1,dynll2a,LOC103397138,LOC100698873,LOC107559583 other downstream 1021134 2037699 ~ 2039836 (+)

Expression


Co-expression Network