tp73 (tp73,LOC107698840)


Basic Information

Item Value
gene id tp73
gene name tp73,LOC107698840
gene type coding
species tiger barb (Puntius tetrazona)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_056706.1
NCBI id CM032075.1
chromosome length 24299999
location 22881023 ~ 22914169 (-)
genome version ASM1883169v1_2021_tiger_barb_Genome

Sequence

>XM_043247500.1
TATGGCCGGTCGGTTCCGTAGCTGTTCGCCGTGAGCGTCGTGTAATCTGCCCTGCGGTGGATTGTCCAACATCCAAGATGTCCCAGCCGTCCACCGCTGATGAGGGAACAACCTTTGAGCACTTGTGGAGCACCCTCGAGCCAGACAGCACATATTTTGAGCTTCCTCAGGCAGGACACTCGGGGGACAGGGTGGCTTCCAGCAGCCTGCCCAGCAACCGCGCTGAAGTCTGCATGGACGTCTACCACATGAGAGACATGAACGACAACGTCATGTCTCAGTACAGCCTACTGAGCAGCAGTATGGAACAAGGCTTGGGGAACAGAGCAGCGTCTACCAGTCCCTACAGCTCAGAGACCACCTCCAACGTGCCAACGCCGTCACCCTACTCCCAGCCAAACTCGACCTTCGAGGCCATGTCTCCAGCCCCGGCCATCCCCTCCAACACTGACTATCCCGGGCCGCACAACTTCGAGGTCACCTTCCAGCAGTCGAGCACCGCCAAGTCAGCCACCTGGACGTACTCTCCGTTGCTCAAGAAGCTGTACTGTCAGATCGCCAAGACCTGTCCGATTCAGATCAAACTGGCTTCCTCGCCTCCGAACGGCAGCGTGATACGAGCCATGCCCATCTACAAGAAAGCCGAGCACGTCACGGAGGTGGTCAAACGGTGCCCTAACCATGAACTCGGACGGGACTTCAACGAAAGTCAGACAGCTCCTGCCAGTCACTTGATTCGAGTGGAGGGTAATAATCTGAGTCAGTATGTTGATGATCCTGTGACCGGCCGACAGAGCGTTCTCGTTCCGTATGAAGCTCCACAGGTGGGGACCGAGTTCACAACCATTCTGTATAATTTCATGTGCAACAGCAGTTGTGTCGGTGGAATGAACCGCAGACCCATCCTCATCATTATCACACTGGAGACGCGAGACGGACAGGTTCTCGGCAGGCGTTCGTTTGAGGGCCGAATCTGCGCCTGTCCCGGTCGAGACCGCAAAGCAGACGAGGATCATTTCAGGGAGCAGCAGGCTCTAAATGAGAGCGTCGCCAAAAACGGAAACGCCAATAAACGAAATTTCAAACAGGCTCCGGTCAACATTACAGGCCCTTCCATCAACATCAAGAAGAGGCGACACGGAGAAGAGGACATGTATTACATACCAGTGCGAGGCCGGGAAAACTTCGACATCCTGATGAAGATAAAGGACAGTTTGGAACTTGTGGAGTTTGTACCTCAACAGTTAGTGGATTCATACagacagcaacagcagcagctccTACAGAGACAGAGCCATGTAGCCTCTCCGTCTCCGTATGGCACGCTCAATAACATGAATAAGATCCACGGCTCCATCAGCAAGCTTCCCTCAGTCAATCAGCTCGTGACCCAGCAGACCCAGCAGAGCGCAGGGCCCTCTGCGTCCATGTCACATATGGGTGGGAACATGCTGGGCGGACACCACATGCAGTCGAACGGCGACGTGAACGGAGCGCATGCGTCTCAGTCTATAGTGTCAACCTCTCACTGTACCCCCCCACCTTACAACCCCGACCCCAGCCTCGTCAGTTTCTTAACCAGCCTGGGCTGCCAAAACTGCATCGACTACTTCACATCACAGGGACTCCAGAGTGTCTACCACCTTCAGACTCTTTCTATGGAGGACCTTGGGGCGCTGAAGATCCCTGAGCAGTTCCGGATGGCGATCTGGAGAGGCCTGCAGGACATGAAGCAGGGCCACGATTACGGCCAGCAGCTCATCCGCTCCAGCAGTAACATGGCCACCATGGCCATCGGCGGCGGGGGAGAGCTGCAGCGGCAGCGCGTCATGGAGGCCGTGCACTTCAGAGTGCGCCACACCATCACCATCCCCAACCGCGGCGCCCCCGCCGGAGCGGAGGAGTGGGCCGACTTCGGCTTCGACATGCCCGACTGCAGGATACACAAGCACTCCATCAAGGAGGAGTTCGCGGAGAGCGACGTTCGCTGAGAGGCGACGGACAGTTCGCGTTTCCATAGAGTAGCACTTCCGTATTTGACCACGGcgacaaaaaaaaacgattcgCTTTTTATGAAGGtgaatcaaatgaatcattttattcgATTGATAGTCATTTGAGGCCTTACGCTAAAATCACAtcacgcaaaaaaaaacaagacccATTAGCTAAAACATATTATTAGGATGTAGTTATGAGCAAGCAGTGTATGGTTTCAGAACATTGCCTTATTTATTTCGGCTTGGTGTAAATAATTATCGTGCAATCATGTATTGAATTACATGTGAAGTTATGCCCGCAGATCAAGTGGATTGCTTGACCCACAAAATCatactttatatttactttttttgaaagaaaaacgcAGGTTTATCGACGCCAGACGTGTACAACTAAACCACTTTCTCATAAATAAGTCatacaaatataacaattagttcattttacaaaaacagcGATGCAAACAAcaccattttttaattattagcattttttttaaaactaagaCACTTTTTTGAAAGTGGCGCTTTAcactgcaactttttttttgattttatgaaTTATGCGTTAAGTATTATGTTATTGACAGGGAGACACTGGATCATCATAAGGGATGTCAGATTTGTAAAGTTTTGTGGTATTAGCCTTGCAGGACAAGGTTTTATTTATCATGCTGAACTGATATAATGTCTATTTTTCCTTTTACCGTACGTAATCGCCGTcttgttagtttgttttaaatgtctgtaaatgtattattttttttatgtaatagtaAATTGATGGCTCAGACAAGGTATTAAGGTGACAACTGTTCATCCTATCCAGGTGACATTTCATCCccagtgtgtatatgtatatatataatatgattttacaattttattttatgagaacatgaatgcattttaaaaaggaaatgtattaaatgtatttttaaaaaatcagcaAAGCACGTCAAATACGAATTTTAGAATAAATGTgctaaattgtaaatatataaaaattggaCTTTAAtcgaaatattattattattattatcaatacaCAGATGATAACCctgggcaactttttgagcaacaCGGATTTAAATTTTCcagacagaaatgtaaaaagacAGAAACTTGCTCAAAAAGTAGCCCGgggtattattatttaattttggggCTGAAAAAGGACATACCTGGATTCAATTTTGTGAGTTTCACCTCTGcgacacaaaagaagaaaaaccatGTACTATTTAAAAACCCAACTCCGCTTTAATATCCCTTTTAACATTGCTAGCACGAAGATGATGAGAAAGTTTGATTTGGTGGTTTGTATGTAGTCAGAGGTACCTTTATTTAACAGGccaatgcatttgtaaataactAGTGTTGGCCGTGTAACTCCATGTTGTTCACGTGACGAGAACAGAACGTTTTAAACTGGGACCCAGGAGGTTAATCGAGGTTAATCGAGGCCGTGGCGGTGAAATACCGTCGTATAGTTTAAAGCACTTTACAGCTTTAGGATATGGTGAACAATGTTCTATTCACAGTTGATATCAGTCAGTATTATGTCATGCCGTGTCATTTTGACAACTACagattttagaaatgtttttaagagtTACTATCTTGTGTTTTCATTAAAGAGCTGTAacgctgtttctttttttttttttatattgccaTGTTTGAATGATGTAAAGTGAgttcttttttcaaataaatgctaaagtGTGCAAATCAAAGGGTGTTTTAATGCGACAAAAGTGCGATGATACAGCATGATTATATcataaaaagaagcaaattagTGTTAGTTAATCGtgtgatgaataaaaagaaaacatggatAGAGTGCAAGTCTTtaagaatagaattagaataaaattaGGGTTGTGCTGTCGGTTTAACTCGTTAGCTTAATTAATTAGTAATAGAAAAATAacttgatttaaatattttaacacactTCTGCCAAACCTGTGTCATCTTGCATTACATACAGTTGACTTTTGACGAATATGAAGCAGGGCAACAACTCTATAAATGCAGTTGTGTGtcctaaaatttaaaatatagtagtttttttttcttattttctcagTATTA

Function

symbol description
tp73 Enables DNA-binding transcription factor activity. Acts upstream of or within embryonic cranial skeleton morphogenesis and regulation of transcription, DNA-templated. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Is expressed in several structures, including gonad; musculature system; nervous system; pharynx; and renal system. Human ortholog(s) of this gene implicated in breast cancer; lung cancer; nephroblastoma; and renal cell carcinoma. Orthologous to human TP73 (tumor protein p73).

NR:

description
tumor protein p73 isoform X2

GO:

id name namespace
GO:0010332 response to gamma radiation biological_process
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator biological_process
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator biological_process
GO:0031571 mitotic G1 DNA damage checkpoint biological_process
GO:0000122 negative regulation of transcription by RNA polymerase II biological_process
GO:0010165 response to X-ray biological_process
GO:0051262 protein tetramerization biological_process
GO:0034644 cellular response to UV biological_process
GO:0043508 negative regulation of JUN kinase activity biological_process
GO:0048701 embryonic cranial skeleton morphogenesis biological_process
GO:0043524 negative regulation of neuron apoptotic process biological_process
GO:0000785 chromatin cellular_component
GO:0005829 cytosol cellular_component
GO:0005634 nucleus cellular_component
GO:0005667 transcription regulator complex cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0002039 p53 binding molecular_function
GO:0003682 chromatin binding molecular_function
GO:0003684 damaged DNA binding molecular_function
GO:0003690 double-stranded DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function

KEGG:

id description
K10148 TP73; tumor protein p73

RNA

RNA id representative length rna type GC content exon number start site end site
XM_043247500.1 True 4103 mRNA 0.44 15 22881023 22914169

Neighbor

gene id symbol gene type direction distance location
rer1 rer1,LOC107698848,LOC107595758,LOC107748969,LOC107678415,LOC107710784,LOC107602473 coding downstream 908 22875118 ~ 22880115 (-)
aak1a aak1a,LOC107678431,LOC107710782,LOC107698849,LOC107748970,LOC108426667,LOC107595757,LOC107602451 coding downstream 6125 22837109 ~ 22874898 (-)
LOC122349927 LOC107710781,LOC107748971,LOC107678464,LOC107698851 coding downstream 56432 22818969 ~ 22824591 (-)
LOC122351014 LOC107757082,LOC107703982,LOC107757083,LOC107757080,LOC107678397 coding downstream 64676 22812855 ~ 22816347 (-)
LOC122350037 LOC107575601,LOC107757083,LOC107574252,LOC107752574,LOC107678367,LOC107678397,LOC107752571,LOC107552256,LOC107703982 coding downstream 90536 22779254 ~ 22790487 (-)
LOC122350809 NA coding upstream 17964 22932133 ~ 22935123 (-)
kiaa2013 si:dkeyp-104h9.5,kiaa2013,LOC107698843,LOC107678452 coding upstream 33687 22947856 ~ 22955895 (-)
clcn6 clcn6,LOC107710774 coding upstream 520702 23434871 ~ 23446449 (-)
LOC122351104 NA coding upstream 543442 23457611 ~ 23475050 (-)
pex10 pex10,LOC107748993,LOC107687115,LOC107691068,LOC107710779 coding upstream 562353 23476522 ~ 23480310 (-)
G66235 LOC107703993,LOC107755595 non-coding downstream 175898 22699448 ~ 22705125 (-)
G66217 LOC107664463,LOC107755600 non-coding downstream 223364 22654971 ~ 22657659 (-)
G66207 NA non-coding downstream 255846 22580402 ~ 22625177 (-)
G66206 NA non-coding downstream 331705 22547651 ~ 22549318 (-)
G66163 gkap1,LOC107562640,LOC107757429,LOC107664507,LOC107678454,LOC107553117 non-coding downstream 493240 22386082 ~ 22387783 (-)
G66337 NA non-coding upstream 68542 22982711 ~ 22983165 (-)
G66339 NA non-coding upstream 71177 22985346 ~ 22986961 (-)
LOC122350914 NA non-coding upstream 137713 23051882 ~ 23054592 (-)
G66368 NA non-coding upstream 326803 23240972 ~ 23245510 (-)
G66372 prdm16 non-coding upstream 468969 23383138 ~ 23383354 (-)
ddx51 ddx51 other downstream 45432 22829204 ~ 22835591 (-)
G66310 NA other downstream 84661 22795622 ~ 22796362 (-)
LOC122350259 LOC107678445,LOC107752560,LOC101882811,LOC107553112,LOC107757078,LOC108426735,LOC107703990,LOC107757081,LOC107553140,LOC107678447,LOC107752570 other downstream 133944 22727180 ~ 22747079 (-)
LOC122349902 nfu1,LOC107678441,LOC107553147,LOC107664472,LOC107570003 other downstream 240700 22637275 ~ 22640323 (-)
gfpt1 gfpt1,LOC107678434,LOC107553119,LOC108426669,LOC107710818,LOC107752562,LOC103362312,LOC101170101,LOC107562636 other downstream 615162 22243202 ~ 22265861 (-)
tprg1l tprg1l,LOC107698845,LOC107710788,LOC107678419,LOC107748986 other upstream 12287 22926456 ~ 22931165 (-)
G66410 LOC107687112,LOC107595766 other upstream 662784 23576953 ~ 23583368 (-)
G66451 LOC107595774,LOC107733967,LOC107748958,LOC107693424 other upstream 743896 23658065 ~ 23663536 (-)
LOC122350426 NA other upstream 906331 23820500 ~ 23821991 (-)
LOC122350723 si:ch211-117c9.5,slc6a8,slc6a7,LOC107601348,LOC107697011,LOC107566000,LOC107673283,LOC107750894,LOC103370863,LOC105906418,LOC107601746,LOC107653404 other upstream 1249798 24163967 ~ 24183176 (-)

Expression


Co-expression Network