CI01000006_06049283_06057849 (TRPC6, TRPC6A, TRPC6B)


Basic Information

Item Value
gene id CI01000006_06049283_06057849
gene name TRPC6, TRPC6A, TRPC6B
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000006
NCBI id null
chromosome length 13024002
location 6049283 ~ 6058876 (+)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000006_06049283_06057849.mRNA
ATGAATCAAAGGAGACCTGTTCTGGAAGATAAAAATCAATCAAAGTATCACACAATTGAAAAGAGGAACAGAAGTAAAGACAATCTACTGATGAACGAAGACTTTGGTGAGGACTCTTATGGCAGTTATGGATACTACCATGGCCTAACACCTGTCGAGGAACGTTTCCTTGATGCTGCCGAGTATGGAAATATACCTGTCGTGCGCCGGATGCTTGAGGAGATCCCTGAGCTGGATGTTAACTGTGTGGACTACATGGGCCAGAATGCATTGCAGTTGGCAGTGGCAAACGAACACTTAGAGGTAACAGAGCTCCTGTTGAAGAAAGACAATCTGTCGCGTATTGGGGATGCACTATTGTTAGCCATCAGCAAAGGTTACACCAGGATTGTCGAGGCCATTTTGAGCCACAAAGCTTTCGCCGACTCCAAGAGACTCACAGCAAGCCCCAGTCAGGCTCCGATGCACGATGACTTTTTTGCGTATGACGAAGACGGCACGCGCTTTTCTCATGATGTCACTCCAATCATTCTAGCATCTCACTGTCACGAATACGAGATCGTGCACATTCTTCTGGGAAAGGGTGCTCGCATTGAGCAGCCACATGACTACTTTTGTGCCTGCGACACCTGCAATTACCATCAAAAGTACGATTCTTTTTGCCACTCCCGCTCGCGTATCAATGCCTACAGGGGATTGGCCAGTCCAGCGTACCTCTCTCTGTCCAATGAGGATCCTGTGCTGGCTGCTCTGGAGCTCAGCAATGAGCTCGCCTCCTTGGCCAATATTGAAAAGGAATTTAAGAATGAATATAGGAAACTTTCTATGCAATGCAAAGACTTTGTTGTGGGGCTTCTGGACCTGTGTCGGAGCACAGAGGAAGTGGAAGCCATTCTGAATGGCGAAGAGGATGAGAATTTAGAACTGCCCGGCCGACCAAGTCTCTTTCGCTTAAAACTCGCAATAAAGTACGAACTGAAAAAGTTTGTGGCCCATCCTAACTGTCAACAACAGCTCTTGTCAATATGGTACGAAAACCTGCCCGAACTCAGGCAGCAGACCACAGCCATTAAGTTCTTAGTGGTTTTAGGTGTTGCAATGGGACTCCCCTTTCTAGCTATGGTGTATTGGGTGGCACCATGCAGCAAGATGGGAAAGATCATGCGTGGCCCTTTCCTTAAGTTTGTGGCACACGCAGCCTCCTTCACTATTTTCCTTGGCCTTTTGGTCATGAACGCTGCAGACCGCTTTGATGGGACAAAGCTGCTTCCAAATATGACCATTCATGACTATCCGACGCAGCTGTTTCGTATGAAAACAACTCCCTTTACATGGATGGAAATGCTCATCATTTCCTGGGTCATAGGGATGATTTGGGCAGAGTGCAAGGAGATCTGGTCTCAAGGTCCAAGAGAATATCTTCTTGAGCCTTGGAATTTTCTAGACTTTGGAATGTTGGCCATTTTTGTGGCATCCTTCATCTCAAGGATAATGGCTTTCTGGCATGCATGTGTAGCACAACGCTATGTTGATGAGCACTACACAGATTTAACCAATGTAACTTTGCCTTTTGAGGTGGGATACTTCCAGTTGGCTCGGATCAATTGGCTCCCGTCTGATCCTCAGTTAGTTTCAGAGGGCTTGTACGCTATTGCAGTGGTCCTGAGTTTTTCTCGAATTGCGTACATCCTGCCAGCAAATGAGAGCTTTGGACCCCTGCAGATATCTTTGGGACGAACTGTGAAGGACATCTTCAAGTTCATGGTTATCTTCATCCTGGTCTTTCTGGCTTTCATGATTGGAATGTTCAACCTCTACTCATATTATCGGGGTGCTAAACAGAATGAAGCTTTCACAACTGTAGAAGAAAGCTTCAAAACATTGTTTTGGGCGATATTTGGCCTTTCTGAGGTCAGATCAGTAGTCGTGAACAATGGACACAAGTTCATCGAGAACATTGGCTATGTTCTCTATGGAGTTTACAATGTGACAGTGGTCATTGTCCTACTCAACATGCTTATTGCCATGATCAACAGTTCCTTTCAGGAGATTGAGGATGATGCAGATGTGGAGTGGAAGTTTGCCCGGGCCAAGCTCTGGTTCACCTACTTTGAGGAGGGCAGGACTCTCCCTGTGCCTTTTAACTTGGTTCCCAGTCCCAAGTCTGTTGTGGGTCTGGTGATGGGGGCTAAAAGTCTCCTGCAGGAGCTTTTTGACAGACACAAAGCCATTATGAAGGGATCTGAGCTCAGTGAGAAAATTATGAAGCGTCTCGTTAAGCGATACATCATCAAAGCTCAAAATGACAAAGAATGTGATGAAGTCAATGAGGGTGAACTGAAGGAGATTAAGCAGGACATTTCAAGCCTTCGCTATGAGCTGCTGGAGGAGAAGTCACACAACATGGAGGAGCTGGCAAAGCTAGGACTCTTAAGTAATATGCCTCATTTCTCCTTTTTGTGTAACAAAAGAATTTCTGTTCAGGTCACAGTTAAGTCTCCAACTAAGCATGAGACGAACTCAGGAACATTTATGTTATGCAAATTAAAAATATCACAGAGTTATGTTGTGAAAGTAAGGCCATGTTTTTGGTTTTTGAAATCCATGAAATCCAAATGCTCCTCAGAGAATGGAAAAATAAAGAATGCAGCAGGCTTCATGAATCAGAGCCGTTTTGTTTGACTCTGCTGACACAATAACACATGCTGCTAAGTTGGCAAAGCTTTGTTTAACCAGAGCAACACAAACCTTTAGATAAAGCCTGCCCAGAATAATAATAAAAAAATAAAATAAAATTTATATATATATATATATATATATATATATATATATATATATATACTTGTGGCNNNNNNNNNNAAATTTATATATATATATATATATATATATATATATATATATATATATACTTGTGGCTAAATCCTGGTAAGGTTTTTATTGTAAAAGCTACTACAGTCTGTAATTGCAGTTCCAAACGTTGGTTCGGGAGGAGCCTAAACATTCAATCATAATTACGAGCGTATATAAGCAGCAGTCACTGCGTCATCCCAGTGCAATTCTTCCAGCATCTCCTCCTCAATTTCTCTTATTCTCCCTCTAAACAGCACTGTTATAGGGGGGTTTAACTCGGAGCTCAAGCCGAGACTTGGGTTCGAGCCTCCTTCGGGGACAGCAAGCCAAGTTTGTTTTACCATTAACCATTCAGACTGAATGGGCAGGCGAACTTGTGAATATGCACTTGAATGGTACATCTTTGACGTCCTTGCTGTTCACATGTTGTAACATCAATTGCAATACTGTAATTGCATTTCCTTTCTGGAAATCACTTTGCTGGTCTCCCCTGGACTTTTTCTTAAAGGTCCTTAGATGATGATGTCAGAGATAGTACCTATCCATCCACAGTACAGTCAGGAAAAACCACTTTTTACAAACAAATGATACCACAGGAGAATTTAACTTACAAAAATACTAATGTGGGTCATACTGATGTACTGTATAGTACAAAGGCAAAGTGAAGTAATCTTTTCACATTTCTAAATCTGGAATTTTTTTTGTCATTTTTCATGTTCTCTCAACAGTGTATATAGAATGCAAAGCAGGCCAAAACTGTGAATGCCTTTTAGATTTGAAATGAATTGGCAAAGATGTATGGATGGAGACAGACAGACGGACAAAAGAACAGGTCAAAACACAATCATGGTTTCAGTAA

Function

symbol description
trpc6b Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in metal ion transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane. Is expressed in trigeminal motor nucleus. Human ortholog(s) of this gene implicated in chronic fatigue syndrome; focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 2; and nephrotic syndrome type 2. Orthologous to human TRPC6 (transient receptor potential cation channel subfamily C member 6).
trpc6a Predicted to enable inositol 1,4,5 trisphosphate binding activity and store-operated calcium channel activity. Predicted to be involved in metal ion transport; regulation of cytosolic calcium ion concentration; and single fertilization. Predicted to act upstream of or within ion transport and transmembrane transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of cation channel complex. Predicted to be integral component of plasma membrane. Is expressed in several structures, including cardiovascular system; gut; integument; keratinocyte; and pectoral fin. Human ortholog(s) of this gene implicated in chronic fatigue syndrome; focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 2; and nephrotic syndrome type 2. Orthologous to human TRPC6 (transient receptor potential cation channel subfamily C member 6).
trpc6 Enables cation channel activity; inositol 1,4,5 trisphosphate binding activity; and protein homodimerization activity. Acts upstream of or within positive regulation of calcium ion transport and positive regulation of ion transmembrane transporter activity. Located in cytoplasm and plasma membrane. Implicated in chronic fatigue syndrome; focal segmental glomerulosclerosis; focal segmental glomerulosclerosis 2; and nephrotic syndrome type 2. Biomarker of pulmonary hypertension.

NR:

description
Trpc6 protein

GO:

id name namespace
GO:0015279 store-operated calcium channel activity molecular_function

KEGG:

id description
K04969 TRPC6; transient receptor potential cation channel subfamily C member 6

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000006_06049283_06057849.mRNA True 3709 mRNA 0.42 12 6049283 6058876

Neighbor

gene id symbol gene type direction distance location
CI01000006_06038315_06045317 ANGPTL5 coding upstream 3599 6038315 ~ 6045684 (+)
CI01000006_06006532_06022059 POLQ coding upstream 27101 6004802 ~ 6022182 (+)
CI01000006_05987812_05989546 NA coding upstream 58746 5987760 ~ 5990537 (+)
CI01000006_05977013_05979433 GUCA1D coding upstream 69393 5976481 ~ 5979890 (+)
CI01000006_05933352_05969576 NA coding upstream 79165 5933174 ~ 5970118 (+)
CI01000006_06095035_06097240 FBXO40.2 coding downstream 36159 6095035 ~ 6097240 (+)
CI01000006_06100199_06103495 FBXO40.1 coding downstream 41323 6100199 ~ 6103523 (+)
CI01000006_06104927_06109730 NA coding downstream 46051 6104927 ~ 6109820 (+)
CI01000006_06111210_06113067 NA coding downstream 52231 6111107 ~ 6113123 (+)
CI01000006_06122278_06122736 NA coding downstream 63203 6122035 ~ 6122751 (+)
G43887 NA non-coding upstream 245122 5792917 ~ 5804161 (+)
G43898 NA non-coding upstream 258369 5789421 ~ 5790914 (+)
G43903 NA non-coding upstream 275334 5771881 ~ 5773949 (+)
G43942 NA non-coding upstream 606360 5442465 ~ 5442923 (+)
G43934 NA non-coding upstream 620965 5428100 ~ 5428318 (+)
G43970 NA non-coding downstream 13521 6072397 ~ 6072706 (+)
G43988 NA non-coding downstream 51290 6110166 ~ 6110406 (+)
G43990 NA non-coding downstream 61482 6120358 ~ 6120735 (+)
G43908 NA non-coding downstream 92997 6151873 ~ 6154727 (+)
G43904 NA non-coding downstream 135293 6194169 ~ 6199969 (+)
G43896 NA other upstream 277508 5770089 ~ 5771775 (+)
G41996 NA other upstream 925134 5117206 ~ 5124149 (+)
CI01000006_03734862_03735227 BANF1, BANF1.S, BANF1.L other upstream 2313305 3734554 ~ 3736035 (+)
G41591 NA other upstream 3209862 2836167 ~ 2839421 (+)
G41424 NA other upstream 3388713 2645662 ~ 2660570 (+)
CI01000006_07167131_07168925 NA other downstream 1107913 7166778 ~ 7168925 (+)
G44872 NA other downstream 1297476 7356352 ~ 7387884 (+)
G45178 NA other downstream 1563115 7607604 ~ 7683671 (+)

Expression


Co-expression Network

Homologous

species gene id symbol gene type chromosome NCBI id location
zebrafish (Danio rerio) XLOC_019586 trpc6a coding NC_007132.7 CM002905.2 22801257 ~ 22812449 (-)
bowfin (Amia calva) AMCG00016308 trpc6a,LOC108429885,LOC108264040,LOC107691992,LOC107713306 coding CM030122.1 CM030122.1 15577433 ~ 15596800 (-)