tyms (tyms)


Basic Information

Item Value
gene id tyms
gene name tyms
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035912.1
NCBI id CM008315.1
chromosome length 41032606
location 22934665 ~ 22939259 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007230333.3
GCATGCAGGCGCGCGCTGTGCTGGAACATTCAtagatacacacacaaagagagacaCGCAGATAGAGCTCCAGCAACATTTTAAACGGTATAACTTCTCTAAaactgtacagatatatatatatatataacaatgcCAGCCACGTCTGAGCTCCTGCACGGGTCGGGCGGTGAAGCGGTGGAGGAGCCGGTTAAGGAGAAGAGCGCTGATCCTGCTGCTCATTTCTCTCTGTTCTGTGATGAGCGCGGATATCTGAACCAGATCCAGTACATTCTACAGAACGGAGTGAAGAAGGGAGACCGGACCGGGACCGGGGTCGTGTCTGTGTTCGGGTTACAGGCCAGATACAGCCTCAGAGATCAGTTCCCTTTACTCACCACCAAGAGAGTCTTCTGGAAGGGGATCTTAGAGGAGCTGCTGTGGTTCATAAAGGGTTCAACAAATGCCAAAGAGCTTTCAGAGAAAGGTGTAAAGATTTGGGATGCGAATGGGTCACGGGACTTCCTGGACAAGAGTGGATTTACTGAGCGGGAGGAGGGAGATCTAGGACCTGTATATGGTTTTCAGTGGAGGCACTATGGTGCTGAATATAAAGACATGCACACAGATTACTCTGGGAAAGGTGTTGACCAATTGCAGAAAGTCATTGACACCATTAAGTCCAATCCAGAAGACAGGAGGATCATTATGTGTGCTTGGAACCCTAAAGatttgcCTCTGATGGCTCTTCCACCCTGCCATGCTCTGTGCCAGTTCTATGTCTCTGAGGGTGAACTGTCTTGCCAATTATACCAGCGCTCGGGGGATATCGGTCTGGGTGTTCCATTCAATATCGCAAGCTATGCCCTTCTGACATACATGATAGCACACATCACAGGACTCAAGCCTGGTGATTTTGTACATACTCTTGGTGATGCCCACATCTACTTGAATCACATCGAACCTCTGAAAGTTCAGCTTCAGAGGGAACCTCGCCCTTTCCCCAAATTGAAGATTCGTCGCACTGTGGAACGCATTGATGATTTCACAGCCGAGGATTTTGAGATTTGTGGCTATGATCCCTACCCCACTATCAAGATGCAGATGGCAGTATAAAAACCACAAACTCTCGGCTTGAGGGAgtagtgtttttaaaacatgtttctgTAATTGTATCTAATGTGTGATGGATGCGTTTGTTGATGATTGGTGCTGGTTTTTGTATGTGGTTACTGAggaaaacaatgtaaatatttgtgtactaatgtacattttttttttttttttttttataattttattgtttttaaggtTTATAAAATTGCActtgaaataaacatttttcaactTTA

Function

symbol description
tyms Enables thymidylate synthase activity. Acts upstream of or within dTMP biosynthetic process and retina development in camera-type eye. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including anterior neural tube; blood; nervous system; optic vesicle; and ventral mesoderm. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); and rheumatoid arthritis. Orthologous to human TYMS (thymidylate synthetase).

NR:

description
thymidylate synthase

GO:

id name namespace
GO:0006231 dTMP biosynthetic process biological_process
GO:0006235 dTTP biosynthetic process biological_process
GO:0060041 retina development in camera-type eye biological_process
GO:0032259 methylation biological_process
GO:0004799 thymidylate synthase activity molecular_function

KEGG:

id description
K00560 thyA, TYMS; thymidylate synthase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007230333.3 True 1331 mRNA 0.44 7 22934665 22939259

Neighbor

gene id symbol gene type direction distance location
clul1 NA coding upstream 1954 22921010 ~ 22932711 (+)
LOC111194171 NA coding upstream 37674 22893635 ~ 22896991 (+)
hacd1 hacd1,LOC107702201,LOC107571282,LOC107568855,LOC107691470 coding upstream 64525 22854584 ~ 22870140 (+)
ncf2 ncf2 coding upstream 216100 22703645 ~ 22718565 (+)
prkdc prkdc,LOC107724397,LOC107742141,LOC107598697 coding upstream 250135 22612645 ~ 22684530 (+)
LOC103031382 NA coding downstream 52203 22991462 ~ 23003994 (+)
adcyap1 adcyap1 coding downstream 77522 23016781 ~ 23022412 (+)
trnat-cgu NA coding downstream 125769 23065028 ~ 23065099 (+)
trnaa-cgc_2 NA coding downstream 126028 23065287 ~ 23065358 (+)
smchd1 smchd1 coding downstream 251205 23190464 ~ 23250746 (+)
G143382 NA non-coding upstream 135837 22754052 ~ 22798828 (+)
G143375 LOC101487086,LOC103370675 non-coding upstream 187857 22745712 ~ 22746808 (+)
G143374 NA non-coding upstream 189019 22743634 ~ 22745646 (+)
G143363 NA non-coding upstream 195730 22737043 ~ 22738935 (+)
G143343 NA non-coding upstream 244761 22689533 ~ 22689904 (+)
G143621 enosf1 non-coding downstream 675 22939934 ~ 22942369 (+)
G143623 enosf1,LOC107086472 non-coding downstream 12054 22951313 ~ 22954599 (+)
G143626 NA non-coding downstream 17552 22956811 ~ 22958211 (+)
G143627 NA non-coding downstream 19009 22958268 ~ 22960220 (+)
G143642 NA non-coding downstream 129115 23068374 ~ 23069875 (+)
G143324 NA other upstream 324218 22535685 ~ 22610447 (+)
G143182 mlrn,LOC103039566,LOC106517213,LOC104925296,LOC105008240,LOC106578694 other upstream 1026351 21811291 ~ 21908314 (+)
G143122 LOC108436138 other upstream 1287960 21645905 ~ 21646705 (+)
LOC103047556 LOC108436107,LOC108267807 other upstream 1322983 21598682 ~ 21611682 (+)
plag1 plag1,LOC107730125,LOC107698667,LOC107660303,LOC107705642,LOC107570428 other upstream 1354941 21569082 ~ 21579724 (+)
LOC111194251 NA other downstream 445909 23385168 ~ 23395240 (+)
LOC111194174 NA other downstream 464429 23403688 ~ 23406894 (+)
G143836 NA other downstream 888689 23827948 ~ 23916082 (+)
ppp3ca ppp3ca,LOC103369319 other downstream 1497120 24436379 ~ 24602402 (+)
G144017 NA other downstream 1767824 24707083 ~ 24711533 (+)

Expression


Co-expression Network