LOC103047294 (gpx4,gpx4a,LOC108429535)


Basic Information

Item Value
gene id LOC103047294
gene name gpx4,gpx4a,LOC108429535
gene type misc
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035901.1
NCBI id CM008304.1
chromosome length 40584741
location 12334344 ~ 12340913 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>TU56432
TTCTGGTGTGGGAGAGAGGAGTGTTCAGAGTGTTTAGTGTGGTAAAAGTGTTAAGAGGCCATGCGCCTCCTAAGCTCCGCGGTGCTGTTCTCCGTGGTGCTGCAGGCAATGGCCGCGCAGTTGGAGGACTGGCAGACGGCGACGTCCATCTATGACTTCAGTGCCATTGATATTGATGGCAATGAAGTGTCCCTGGACAAATACAGggGTAAAGTGGTCATCATTACCAACGTTGCTTCCAAATGAGGCAAAACCCCCATAAACTACTCTCAGTTTGCAGAGATGCACGCCAAGTACGCTGAGAAAGGTTTAGCCATCCTGGCCTTCCCATCCAACCAGTTTGGAAATCAGGAACCAGGCTCCAGTGCACAAATCAAAGAATTTGCGAAGTCTTACAACGCACAGTTTGACATGTTCGGCAAGATTGATGTGAATGGGGCCGACGCTCATCCTCTGTGGAAGTGGCTGAAGAGCCAGCCCAATGGCAAAGGATTCCTGGGAAATGGAATCAAGTGGAACTTCACTAAGTTCCTGATTAACCGTGAGGGCCAGGTTATGAAGAGATACTCTCCAATGAGTGATCCAAGTGTGGTGGAAAAGGATCTGCCCAAATATCTGTAGCTCTGTGATGATGGCACCTTAATTTAGGCCCCTATCCTCTCCTGTGGATCGCTGACTGTCAGTGGGATCAAACCATGGACTAATGACGGTCTGTCTGGAAACCCGTCGTACGGAAAGGACAGACCTGATGCATTTGGCGTGCAAAACCTCCTGGGTGGATCACCAGGACACAAGCGGTCAGCCGGAGAGGGTCCCTGTTCTTCCACTGTTCTAATGCTCTCACATTATAATAAATTCTACTGTACTTACATATGTGTAACTATTTCTGAATAAACTCACTGAATCTCAATTTAAACTGGAATTGTCCTGATTTATTGACACTG
>XR_002649936.1
GGCGGGGTGTTGAAGAGTTACAGTGTTATTCAAGTCCAGTTACCCAACAGCTCCGGAGAAGAAAGAGCCTTTTATTGTGGGTTTCACTGCCTGATCCCACACATCCAGGCTGTGATGTAACTGTCCTCTGCAGAGGACCTTCAACGTTCTGCAgatgaaaacagcaaaaatgcaGTTTATTAACAGCGTGTTGTTCTTCGGAACTCTGGCAGGCAGTGGGATGATGGGCATGATGGCCGCGCAGTTGGAGGACTGGCAGACGGCGACGTCCATCTATGACTTCAGTGCCATTGATATTGATGGCAATGAAGTGTCCCTGGACAAATACAGggGTAAAGTGGTCATCATTACCAACGTTGCTTCCAAATGAGGCAAAACCCCCATAAACTACTCTCAGTTTGCAGAGATGCACGCCAAGTACGCTGAGAAAGGTTTAGCCATCCTGGCCTTCCCATCCAACCAGTTTGGAAATCAGGAACCAGGCTCCAGTGCACAAATCAAAGAATTTGCGAAGTCTTACAACGCACAGTTTGACATGTTCGGCAAGATTGATGTGAATGGGGCCGACGCTCATCCTCTGTGGAAGTGGCTGAAGAGCCAGCCCAATGGCAAAGGATTCCTGGGAAATGGAATCAAGTGGAACTTCACTAAGTTCCTGATTAACCGTGAGGGCCAGGTTATGAAGAGATACTCTCCAATGAGTGATCCAAGTGTGGTGGAAAAGGATCTGCCCAAATATCTGTAGCTCTGTGATGATGGCACCTTAATTTAGGCCCCTATCCTCTCCTGTGGATCGCTGACTGTCAGTGGGATCAAACCATGGACTAATGACGGTCTGTCTGGAAACCCGTCGTACGGAAAGGACAGACCTGATGCATTTGGCGTGCAAAACCTCCTGGGTGGATCACCAGGACACAAGCGGTCAGCCGGAGAGGGTCCCTGTTCTTCCACTGTTCTAATGCTCTCACATTATAATAAATTCTACTGTACTTACATATGTGTAACTATTTCTGAATAAACTCACTGAATCTCAATTTAAA
>XR_002649937.1
GTTCTGACCTGGGAGAGTGAAGAGTTCTGGTGTGGGAGAGAGGAGTGTTCAGAGTGTTTAGTGTGGTAAAAGTGTTAAGAGGGTGCTCAGGCGTGCTGCAGGCTGCTTCAGCAGCCATGCGCCTCCTAAGCTCCGCGGTGCTGTTCTCCGTGGTGCTGCAGGCAATGGCCGCGCAGTTGGAGGACTGGCAGACGGCGACGTCCATCTATGACTTCAGTGCCATTGATATTGATGGCAATGAAGTGTCCCTGGACAAATACAGggGTAAAGTGGTCATCATTACCAACGTTGCTTCCAAATGAGGCAAAACCCCCATAAACTACTCTCAGTTTGCAGAGATGCACGCCAAGTACGCTGAGAAAGGTTTAGCCATCCTGGCCTTCCCATCCAACCAGTTTGGAAATCAGGAACCAGGCTCCAGTGCACAAATCAAAGAATTTGCGAAGTCTTACAACGCACAGTTTGACATGTTCGGCAAGATTGATGTGAATGGGGCCGACGCTCATCCTCTGTGGAAGTGGCTGAAGAGCCAGCCCAATGGCAAAGGATTCCTGGGAAATGGAATCAAGTGGAACTTCACTAAGTTCCTGATTAACCGTGAGGGCCAGGTTATGAAGAGATACTCTCCAATGAGTGATCCAAGTGTGGTGGAAAAGGATCTGCCCAAATATCTGTAGCTCTGTGATGATGGCACCTTAATTTAGGCCCCTATCCTCTCCTGTGGATCGCTGACTGTCAGTGGGATCAAACCATGGACTAATGACGGTCTGTCTGGAAACCCGTCGTACGGAAAGGACAGACCTGATGCATTTGGCGTGCAAAACCTCCTGGGTGGATCACCAGGACACAAGCGGTCAGCCGGAGAGGGTCCCTGTTCTTCCACTGTTCTAATGCTCTCACATTATAATAAATTCTACTGTACTTACATATGTGTAACTATTTCTGAATAAACTCACTGAATCTCAATTTAAA

Function

symbol description
gpx4a Predicted to enable glutathione peroxidase activity and phospholipid-hydroperoxide glutathione peroxidase activity. Predicted to act upstream of or within response to oxidative stress. Predicted to be active in mitochondrion and nucleus. Is expressed in epidermal superficial stratum; gut; liver; otic vesicle; and yolk syncytial layer. Human ortholog(s) of this gene implicated in spondylometaphyseal dysplasia Sedaghatian type. Orthologous to human GPX4 (glutathione peroxidase 4).
gpx4 Enables glutathione peroxidase activity; identical protein binding activity; and phospholipid-hydroperoxide glutathione peroxidase activity. Involved in arachidonic acid metabolic process; lipoxygenase pathway; and protein polymerization. Located in cytosol. Part of protein-containing complex. Implicated in spondylometaphyseal dysplasia Sedaghatian type.

NR:

description
PREDICTED: phospholipid hydroperoxide glutathione peroxidase, mitochondrial-like isoform X1

GO:

id name namespace
GO:0006979 response to oxidative stress biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0004602 glutathione peroxidase activity molecular_function

KEGG:

id description
K00432 gpx, btuE, bsaA; glutathione peroxidase

RNA

RNA id representative length rna type GC content exon number start site end site
TU56432 False 944 TUCP 0.48 8 12336542 12340913
XR_002649936.1 True 1040 misc_RNA 0.48 7 12334344 12340885
XR_002649937.1 False 972 misc_RNA 0.49 7 12336518 12340885

Neighbor

gene id symbol gene type direction distance location
LOC103046074 hmha1b,LOC108429536,LOC108271042,LOC107655244,LOC107669820 coding upstream 11272 12287917 ~ 12323072 (+)
LOC103046586 LOC108429538 coding upstream 49125 12248637 ~ 12285219 (+)
LOC103045466 LOC108429539,LOC108271013,LOC106573581,LOC107599449 coding upstream 93938 12145212 ~ 12240406 (+)
trnaa-agc_12 NA coding upstream 221140 12113132 ~ 12113204 (+)
LOC103025613 ncan,LOC107097932,LOC103150419,LOC107554802 coding upstream 256366 11814497 ~ 12077978 (+)
LOC103021640 pip5k1c,LOC108429534 coding downstream 701 12341614 ~ 12388429 (+)
LOC103047600 rab11b,LOC108429533,LOC107599444,LOC107655249,LOC107592688,LOC108280567 coding downstream 57360 12398273 ~ 12405148 (+)
march2 march2,LOC106613717,LOC107592682,LOC107655247 coding downstream 66633 12407546 ~ 12419643 (+)
hnrnpm hnrnpm,hnrpm coding downstream 79674 12420587 ~ 12429846 (+)
LOC103025446 nphs2 coding downstream 308838 12649751 ~ 12657114 (+)
G41961 NA non-coding upstream 6106 12327895 ~ 12328238 (+)
G41954 NA non-coding upstream 48364 12285553 ~ 12285980 (+)
G41906 NA non-coding upstream 212914 12118432 ~ 12121430 (+)
G41842 NA non-coding upstream 612540 11721332 ~ 11721804 (+)
G41841 NA non-coding upstream 613349 11720121 ~ 11720995 (+)
LOC107197698 NA non-coding downstream 91114 12432027 ~ 12437339 (+)
G41975 NA non-coding downstream 113582 12454495 ~ 12456795 (+)
G42070 NA non-coding downstream 293549 12634462 ~ 12634735 (+)
G42091 NA non-coding downstream 346612 12687525 ~ 12692753 (+)
G42103 atpaf1 non-coding downstream 401228 12742141 ~ 12744624 (+)
tmem221 tmem221 other upstream 575636 11753887 ~ 11758708 (+)
tmem161a tmem161a,LOC107728546,LOC107687722,LOC107554814,LOC107599454,LOC107719614 other upstream 624661 11669447 ~ 11709683 (+)
G41828 LOC108429549,LOC108271147 other upstream 754015 11571226 ~ 11580329 (+)
LOC103037553 LOC107753862,LOC107597184 other upstream 2311380 9995709 ~ 10022964 (+)
LOC103022991 NA other upstream 3398858 8921928 ~ 8935486 (+)
G42068 NA other downstream 291903 12632816 ~ 12633429 (+)
G42096 LOC108429524,LOC108271269,LOC103369106,LOC106613566,LOC106574586 other downstream 364646 12705559 ~ 12715028 (+)
G42208 ier5 other downstream 1107679 13448592 ~ 13450477 (+)
LOC103032215 NA other downstream 1168107 13509020 ~ 13522257 (+)
LOC103034435 NA other downstream 1276170 13617083 ~ 13622042 (+)

Expression


Co-expression Network