mknk1 (mknk1)



Basic Information


Item Value
gene id mknk1
gene name mknk1
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035901.1
NCBI id CM008304.1
chromosome length 40584741
location 15227150 ~ 15234385 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_015603344.2
gttgtgttttttcttctcagTCTCCCGCCCCGCGCGCTTGCACTAGCTGACAGACTGGCAGAGGCAGGCAGGACCGGCGCGAACTCCAGCTTGCAGGGATGGTGAGGCAGAGCCAGCTCCACTGCACGGGCCAGATGACCAGAGAGTCTTTGGCATCTGGTCCATCAGATGGTGATGCAGGCCTCCCTCCGCTTCCTCCTGCCTCCCGCTGTGCCTCCCAGACATCTTCAGTGGGGATGGAGAGCAGCCAGCCAGTGAATATTGCAGACTCAGGGATACGCAGGAAGAAAAAGCGCCGGACCCGAGCCGCAGACAGCTCAACAGACACATTCAGTGATCTCTACAAACTCACGGATGAGGTGCTAGGGCAAGGAGCCTATGCTAAAGTTCAGTGCTGTGTGAATCTACAAAATGGCAAAGAATATGCTGTGAAGATCATTGAGAAGATTGCTGGCCACAGTCGGAGCAGGGTGTTCAGAGAGGTGGAGACCTTATATCAGTGCCAGGGGAATAAAAACATCCTGGAGCTCATTCAGTTCTTTGAGGATAATAGCTGCTTTTATTTGGTGTTTGAAAAGCTGAATGGAGGCTCCATTCTAACACACATTCAGAGGAGGAAGCACTTTGATGAAAGGGAAGCCAGTCATGTTGTCCGGGATATAGCTAATGCTCTTGACTTCCTGCACACTAAAGGAATTGCTCACCGGGATCTGAAACCTGAAAACATCCTTTGTGTACATGTCGATAAGGTGTCTCCTGTGAAGATCTGTGATTTTGACCTGGGAAGTGGAGTAAAGTTGAGCAGTGCCTGTACTCCTATAACTACACCAGAGCTTACCACAccgTGTGGCTCAGCTGAGTACATGGCTCCTGAGGTGGTGGAGGTCTTTACAGATGAGGCAACCTTCTACGATAAACGATGTGATCTCTGGAGCCTTGGAGTTATACTCTACATCCTGCTTAGTGGCAGTCCCCCTTTCACTGGCCACTGTGGCACTGACTGTGGCTGGGAGAGAGGTGAAACCTGCCGTGCCTGCCAGAACAACCTGTTCGAACGAATCCAGGAGGGAAAATATGAGTTTGATGAACGGGACTGGGCTCATATCTCAGACAGTGCCAAAGACCTGATCTCTCGGCTGCTGGTGCGAGATGCTATGCTGCGGCTCAGTGCTGCACAGGTCCTACAGCACCCGTGGGTGCAAGGGaatgctcCTGAAAGAGGTCTTCCAACTCCACATGTCTTACAAAgGAAGTGCAGCACTAAGGACCTGACTCTGTTTGCGGCCGAGGCCATGGCTTTTAACAGGCAGCTCTCTCAGCAGGACGAGGAGCTGGAGCAGGATGAGGGCGGGGCCATCGTATGCTCTATGAGACTCTCACCTCCCTCCAACTCCAGACTAGCCCGACGCAGAGCGCAGTCCCTTGCACTTCGCAGCACTAACGAGTTCCTGTCTACTGCGCAGGTGCCAGAATAAGCCTATGCATTATATGAACATGTCTTATACTTCCTACACACTTTCTCAGTACAAATGCACATACTACACTGCTGCATTTGATGATCTTAaattacacatacatacatacacacacacacacacacacaaatgcataaacacacacagtatttaagtatttattaccAAATATTTGTGGCTCAGAAAGATTTACAGTGGTGCTTGGGTAGTAAGgaaaatacagatatttttattttagtctagTTTACTAGAATGATTCTTCTTTTACccttgtatgtttttttaaactaaatattttaggatgtttttagtttaaaacactggtgttttgttgcacatttgTTCGCTTTAGTTGCGTTGTGGTCTTGTTCTCATGGTTTAAACTATGTTTCAGGTTGGGACTACAGTTAAGCCCAGTACTTCTTAACAGCCAGTGTAAATAGTGTTGAGACTTGAGGAAATGCATGAAACCATACTGCCTTTtgcatttatatacagtgtaagAGTGGTGAAATTACGGACCTCcctattgattatatatttacctcaaaTCCAGTTTGCACAttgtttttgcacatttttactacaaGCAGTGTTACTGACTCGGCCAGGAAGTAGCatgctttttgtaaaaaacattGCTGGACTTCTAGAAAGTTTCAACTAAAATGAAAGGTTAATTTTACACTTGTAAATGTCAGTACATGTTGCACAGCTgtgttcttgttcttttttttttttaagtattttgttCTGCATATCTCTATTTTTACACTATGTTTGTGTTTACAGTTATtgattttaatttgtattttttaaaatgttaattaatagaGAATTTAACTCTTAAA

Function


symbol description
mknk1 Predicted to enable calcium-dependent protein serine/threonine kinase activity; calmodulin binding activity; and calmodulin-dependent protein kinase activity. Predicted to be involved in intracellular signal transduction; peptidyl-serine phosphorylation; and protein autophosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human MKNK1 (MAPK interacting serine/threonine kinase 1).

NR:

description
MAP kinase-interacting serine/threonine-protein kinase 1-like isoform X1

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function

KEGG:

id description
K04372 MKNK, MNK; MAP kinase interacting serine/threonine kinase

RNA


RNA id representative length rna type GC content exon number start site end site
XM_015603344.2 True 2326 mRNA 0.45 14 15227150 15234385

Neighbor


gene id symbol gene type direction distance location
LOC103027889 mob3c,LOC103027889,LOC108438648,LOC108270829,LOC106574029,LOC106613547 coding upstream 1980 15213259 ~ 15225170 (+)
LOC103027567 LOC108438649,LOC108270756 coding upstream 56512 15143469 ~ 15170638 (+)
LOC103026176 bt3l4,btf3l4,LOC103026176,LOC105028135,LOC107562065 coding upstream 85754 15138264 ~ 15141396 (+)
ptgfr ptgfr coding upstream 90741 15130977 ~ 15136409 (+)
zgpat zgpat coding upstream 129937 15091371 ~ 15097213 (+)
atp5b atp5b,LOC107723059,LOC100693141,LOC102199207 coding downstream 18530 15252915 ~ 15257121 (+)
LOC103028308 abcb11,abcb11b,LOC108438644,LOC107692229,LOC107602798,LOC108270741,LOC105911976,LOC103354593 coding downstream 41041 15275426 ~ 15296603 (+)
LOC103028625 NA coding downstream 122427 15356812 ~ 15376156 (+)
LOC103030416 LOC103030416,LOC108438642 coding downstream 149425 15383810 ~ 15403511 (+)
LOC111192508 NA coding downstream 170597 15404982 ~ 15413569 (+)
G42756 LOC108438650,LOC108270818,LOC107656106,LOC107753833,LOC107562086,LOC107602768,LOC107723066 non-coding upstream 35180 15102476 ~ 15191970 (+)
G42763 NA non-coding upstream 61456 15164715 ~ 15165694 (+)
G42648 txlng non-coding upstream 165703 15058618 ~ 15061447 (+)
G42647 txlng,LOC107665847 non-coding upstream 169475 15057215 ~ 15057675 (+)
G42637 txlng non-coding upstream 172270 15017800 ~ 15054880 (+)
G42807 NA non-coding downstream 143616 15378001 ~ 15378608 (+)
G42810 NA non-coding downstream 180292 15414677 ~ 15415189 (+)
G42813 NA non-coding downstream 186327 15420712 ~ 15421122 (+)
G42814 NA non-coding downstream 186767 15421152 ~ 15421453 (+)
G43035 NA non-coding downstream 800813 16035198 ~ 16037119 (+)
G42605 NA other upstream 327902 14895062 ~ 14899248 (+)
eps15l1 eps15l1 other upstream 1092604 14070423 ~ 14134546 (+)
LOC103037142 LOC108429501 other upstream 1369789 13810833 ~ 13857361 (+)
LOC103034435 NA other upstream 1605108 13617083 ~ 13622042 (+)
LOC103032215 NA other upstream 1704893 13509020 ~ 13522257 (+)
LOC103036127 cunh19orf24 other downstream 744101 15978486 ~ 15984632 (+)
LOC103040819 reep6,LOC107698004,LOC107745351,LOC107658751 other downstream 1206546 16440931 ~ 16446287 (+)
LOC103044285 NA other downstream 1582216 16816601 ~ 16819251 (+)
LOC111192574 NA other downstream 1713995 16948380 ~ 16950360 (+)
dda1 dda1,LOC105913185,LOC107685208,LOC105012003 other downstream 1778082 17012467 ~ 17017856 (+)

Expression



Co-expression Network