bmp4 (bmp4)



Basic Information


Item Value
gene id bmp4
gene name bmp4
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 26604718 ~ 26613764 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>NM_001291252.1
GAGATCAGTCTGAGAGTGAGGGAGCGCGAGCgagtgtgagtaagtgagtgagcgagtgtgtTGGTGAGAGTCGCGCGCGCCCTGCTCTGGAGCTACCCGCCTGCCCGCGCTCTGTCCCGGGACAGTTCGGACCTAATGAGCCGCGCGAGCTTCTGGCAGCGCTCTGACCCGTGTTTACCGGACTTGTGTCGCGAGGCCTGAGCGCGTTTGGAGGAGCCCGTGCGCCCGTCCCGTTTCGGTTTCGCTCTGAGGACACCGCGCCTCTACCCATGGACAAGACTCTCTCCAAAGTCCTCAAGCAGCCTCCCAGCACCACGTAACATTTCCTCAAAGAACTCGTCCGGCGTCGGCTCCCAACAAACATGGACTGTTTTCCCATGCTTTATTTTCTGTCGAGACATCATGATTCCTGGTAATCGAATGCTGATGGTCATTTTATTATGCCAAGTCGTACTGGGAGAGAGCAACCATGCTAGTTTGATACCTGAGGAAGGGAAGAAGAAAGTGTCGGGTCATCACCCGGGTCAGAGTCATGAACTGCTGCGGGACTTTGAGGCCACGCTGCTGCACATGTTCGGCCTGCAGAGGCGGCCACGGCCCAGCCGCTCAGCAGTGGTGCCCCAGTATCTGCTGGACCTCTATAGGCTTCAATCGGGCGAGGCGGACGAGGCCGGAGCGCAAGAGGTCAACTTTGAGTACCCCGAGAGGTCCACGAGCCGAGCCAACACTGTAAGAGCATTCCACCATGAAGAGCACATGGAGCAGGTGCCGTCAGACGGGCCATACATGACTGGCACTCCACTGCGCTTCATCTTTAACCTCAGTAGCATCCCAGAAGACGAGCTGCTGTCCACAGCCGAGCTGCGTTTGTACAGGCGGCAGATCGAAGAGGCCATCTCAGAGGTCCAGGACGAGGGAAACGAGGGCCTCCACCGGATAAACGTGTACGAGGTGCTGAAGCCGCCGCGCTCTGGGCAGCTAATCACGCGGCTTCTGGACACAAGACTGGTGCACCACAACACGTCCAGCTGGGAGAGCTTTGACGTGAGTCCAGCTGTGCTGCGCTGGACTCGCGACCGCTTGCCCAATCACGGGCTGGCCTTGGAGGTGCTACACCTGAACCAAACGCCTCGGCACCAGGGCAAGCACGTCCGCATCAGCCGCTCCCTGCACCAAGCTCCAGACGAAGACTGGGACCAGCTGCGCCCACTGTTGGTGACTTTTGGCCACGATGGCAAAGGCCACCCGTTAACACGCAGGACCAAACGCAGCGCCAAGCAGCGAGGCCGCAAGCGCAATCGCAACTGCCGGAGACATGCGCTGTATGTGGACTTCAGTGACGTGGGCTGGAATGACTGGATAGTAGCCCCTCCTGGCTACCAGGCCTACTACTGTCATGGGGAATGCCCATTCCCTCTGGCGGACCATCTGAACTCCACTAACCACGCTATTGTACAAACACTGGTCAACTCGGTGAACAGTAATATCCCCAAGGCCTGCTGCGTGCCCACTGAGCTCAGTGCCATCTCAATGCTCTACTTGGACGAGACTGACAGGGTGGTCCTGAAAAACTACCAAGAAATGGTAGTGGAGGGCTGCGGCTGCCGCTAGCTGGGTTACGAAAAATCCAGCCGGCCCCATTCTACGCTCAAATATCTTCACTTGGACGCTTATTTATAACGTTTATTTTGAGATGTATGTTTGTCTCCTTTTTGTTTCCTTGACCATATGATCATATATtttgacaaaatatatatatatttatatctacatattaaaaaaataaaagtgagaccttattttaaacattaataagaaTCTGTACAACTTTTCATAATGTATATTAGAGTGTATAAGGGTTTTTAAATGAGaaaagaatgcaaaaaaaacaccaaaaaagtaAAGTATGTATACTggtaatatttatttctttcatactctatacatttacaaaaaaatgggaAATGCATAACCTCCCAGCCAACTTCCTATTTGAGCAGATGAACAAATGCAATATGCATTATTTGTGTACGAAAATAGAGCACTGTGTGAAATGCTGAACTGATTTGTGTGAGGAATCAGTTGAAGAAATCATAAATGTACTTTGATTTTAATTCACGTTTTTGCATCAACTTTTAGACATGTGATTTTAGATGTCCCCATaatttgttcctttttttaaataaatggtgAAACG

Function


symbol description
bmp4 Predicted to enable BMP receptor binding activity and cytokine activity. Acts upstream of or within several processes, including animal organ development; determination of bilateral symmetry; and embryonic morphogenesis. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cardiovascular system; fin; head; inner ear; and mesoderm. Human ortholog(s) of this gene implicated in several diseases, including CAKUT (multiple); cleft lip; orofacial cleft 11; ossification of the posterior longitudinal ligament of spine; and otosclerosis. Orthologous to human BMP4 (bone morphogenetic protein 4).

NR:

description
bone morphogenetic protein 4 isoform X1

GO:

id name namespace
GO:0040007 growth biological_process
GO:0005576 extracellular region cellular_component
GO:0008083 growth factor activity molecular_function

KEGG:

id description
K04662 BMP4; bone morphogenetic protein 4

RNA


RNA id representative length rna type GC content exon number start site end site
NM_001291252.1 True 2197 mRNA 0.51 4 26604718 26613764

Neighbor


gene id symbol gene type direction distance location
snx14 snx14 coding upstream 98206 26488033 ~ 26506512 (+)
LOC103026145 LOC108270054,LOC108423543 coding upstream 120096 26474775 ~ 26484622 (+)
LOC103029223 akirin2,LOC100499587,LOC100379102 coding upstream 170526 26425098 ~ 26434192 (+)
ptpn21 ptpn21 coding upstream 184408 26401087 ~ 26420310 (+)
LOC103030701 NA coding upstream 243972 26357779 ~ 26360746 (+)
LOC103023862 ddhd1 coding downstream 79654 26693418 ~ 26716015 (+)
stxbp6 stxbp6 coding downstream 182044 26795808 ~ 26897068 (+)
c9h15orf41 cunh15orf41,c9h15orf41,cssa01h15orf41,clg19h15orf41,LOC105897278 coding downstream 814988 27428752 ~ 27506291 (+)
spred1 spred1 coding downstream 1157029 27770793 ~ 27813908 (+)
LOC103043868 atxn3,LOC108423524,LOC106596382,LOC107575702,LOC107683100 coding downstream 1234913 27848677 ~ 27855382 (+)
LOC111193231 NA non-coding upstream 38874 26507339 ~ 26565844 (+)
trnay-gua_9 NA non-coding upstream 96593 26508040 ~ 26508125 (+)
G83672 NA non-coding upstream 181657 26422514 ~ 26423061 (+)
G83663 NA non-coding upstream 264446 26339831 ~ 26340272 (+)
G83661 NA non-coding upstream 265019 26339182 ~ 26339699 (+)
G83760 NA non-coding downstream 105214 26718978 ~ 26719365 (+)
G83759 NA non-coding downstream 105871 26719635 ~ 26723005 (+)
G83761 NA non-coding downstream 110575 26724339 ~ 26724613 (+)
LOC111193232 NA non-coding downstream 291117 26904881 ~ 26924218 (+)
G83785 NA non-coding downstream 433782 27047546 ~ 27054268 (+)
spata7 NA other upstream 205451 26392890 ~ 26399267 (+)
LOC103031022 LOC103031022,LOC108423548 other upstream 277380 26321185 ~ 26327338 (+)
c9h14orf132 csgr16h14orf132,LOC108423442,LOC108269530,LOC108413331,LOC107582175 other upstream 299335 26275001 ~ 26305383 (+)
G83602 NA other upstream 351116 26235498 ~ 26253602 (+)
LOC103033015 LOC108423550,LOC108270308 other upstream 629435 25919557 ~ 25975283 (+)
fermt2 fermt2 other downstream 114059 26727823 ~ 26777488 (+)
fam98b NA other downstream 1202041 27815805 ~ 27822211 (+)
LOC103044189 LOC108423527,LOC107677688 other downstream 1210492 27824256 ~ 27831584 (+)
LOC107197841 NA other downstream 2356500 28970264 ~ 28970839 (+)
LOC103045392 NA other downstream 2385738 28999502 ~ 29025114 (+)

Expression



Co-expression Network