gckr (gckr)


Basic Information

Item Value
gene id gckr
gene name gckr
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 24981376 ~ 24997874 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007252055.3
TGTGAATGAAACCAGAGAATACTGAGTACATGGGATTGGTTTGTTACATCAGAAGTCACCAAATATCACTACAAAATAGAAGAAATGCAACACTGGGAGCAATCAGGTTACGAGCCGTCCTTACCCATCACAGAGAAATCAAATCCAATCACCACAGATATCGATAGAGCAGACCCCAACGGGATTGTACAAATGCTGGAAAAATGTGATGCAGAGATGTTTCAGAAAACAGTGCATGAAGACTCCATGTATCAGaaattgaacagctgttctgtgatccAAACAATGGTGGATATATCTAAGAAAGTGGAAATGATTCTCAAGGATCCAGAAAACAGTCTGATTGTACTGAGTGGATGTGGTACCTCAGGCCGTGTTGCATTTCTTTTGGCGACATCCTTTAACAGATGGCTCGCTGCTCTTCATGAAAATCAAATCTATTCTTACATCATTGCTGGAGGTGACAAggcCCTGCTGACATCACAGGAGGCTCCAGAGGACAACCCCTCGCTGGGAGCACTCATGCTGGACAAGGTTTGTTCGGGCAAGAAGCACGTCCTCTTTTTTGGGATATCCTGTGGTTTGTCCGCTCCTTTTGTTGCTGGACAGCTTCACCTCTGTCTGAACAACCTGGAGGTCTTCACTCCAGTGCTGGTTGGGTTTAATCCTGTGAACATGGCACGGACTGAGCTCATGCGGGACTTTCCATCAAACTTCAGGAAGATTGCagagaaaatgagtgaaatgCAGAAACACCAAAGGGCTTTTGTGCTTAATCCAGCAGTGGggCCTGAAGCTATTACCGGATCTTCAAGAATGAAAGGAGGAAGTGCCACAAAACTAATGCTGGAAACTGTTCTTCTGGCGGGACATGAAGCTATGTACAATAAGACAGCAGTAACACCTGATGGTGAGTTGGCCTTGATCGAAATGAATGAGAAAGTTCATAAAGTCACAtactcaaagaacaaaaaactgGCCGCCCTGGTTCAGAAGGCTGGAGTCAGCCTGCGGGGGAAAGGACATGTGTATTACCTTGGATGGCAAACTCTAGGCATTATTGGGATTATAGACGCCAGCGAATGCATTCCAACATTTGGAGCAGCCTTTGAAGATATCAGAGGCTTTATTTGCAGAGGCTTCAGTGAAATCAACAACAAAGAGGGAGACCTGTCATCTGAGGGACTACATTTCTCTATCAGCCACAAGGACTTTGTGAAGAGGATTTTACCCAGCCTGAGTGACAATGACATGGTGATTTTTCTCTTCAGTGTACATGATGACCTGAATGAGGTGTCTGAGTTGGCCAAGTGTGTAGGACATAATACATCAAATATCCATGCACTCATCCATGACCTTGATGGACACTGTGTTCCAGACAGCATTAAGGGCTTATTTATGACTGCCCTCAACATCACATGGCCGTCCTCTTTATATGAACAGCGCTCGATCCTAATGAACCAGCACTGGGAACTTTCTACCAAATGGTGCCTCAACGCAATCAGCACAGGTGCTCATATTCTAAAAGGGAAAGTGTACAAGAATTACATGATAGATCTCAGAGTAACCAATAGCAAACTCTACAGAAGAGCTATTGGTATGTTACAGAGGTTCACGAATAGCACCCAAACACAGAGTGAAACAGCTCTACTGAAATCCATCTATTTTGTGGAGGAGTTGACCGAAGAGATAAGCTCAGCAGAcgtcacacaacacacactgacgGCTAACCAAAAGGACCAGGTTGTTCCCACTGCACTGGTGATGCTACAGACTGGCTGTTCGCTTGCTGAGGCAAAGTCTCACTTAGATGCTCACCCTGTGATTCGAGATGCAGTGGCTGCCTGCCTGAGGTTGTCTTAATGTGCTGAAGGTCTGAAGACTGCAGCCTGTGAATAGAGCAGTAAAAATTAATAGGTATATAATAAGTAACAATTATGATATATGATGAATAATCGTAAAATGTACAACAAAAGATGTAGTCCCTTAAAGTGCAAACAAATATTGCTGTTATTTGCTTTAGGATTGCTAataactactactaatactatcaAAAACTTTTACTACATGTAATGGCACAGGGACTAGTATcacgtcccatgacttttgccatgtctcattGGAGCTAAAGAACATGGCACAGACCAGTGGGGTATGCGAATGTGGAGGTGTTTTCTGCTAGAGTTGCTGGTCTGACCATGCTAGCCTGATTCTGCTGGTCTTGATCATTAGTTAAGATGACTGTATTTTGTACAATCTCAGGATATTCACTAGATCTAAAGTGctgaaatggtaaaaatatactGAAGAAAACTGGAACAACATGGAAAACCTTTACAACAAAGTTATTTCTTCtattcaaataaattatttcagttcTGTATAAAACCTTTCTTGTTATGTAATAATGAACTAAATGGCaaaatttacagtgttttaccgtCGCGAATCTTTCATTAATTAAGTTTATGCTCAATCAATTTTAAGCAAactgtcaaatttaaataaacatacagtaatgtgctgtgtgttttggACACCTGTGGAAATGtttagcaaagaaaaaaaatcttatctgtgaagtaagtgtttattagctcagtaaaacactagcattacaataaat

Function

symbol description
gckr Predicted to enable several functions, including carbohydrate binding activity; enzyme inhibitor activity; and fructose-6-phosphate binding activity. Acts upstream of or within endocrine pancreas development; glucose homeostasis; and pancreas regeneration. Predicted to be active in cytosol; mitochondrion; and nucleoplasm. Human ortholog(s) of this gene implicated in end stage renal disease and type 2 diabetes mellitus. Orthologous to human GCKR (glucokinase regulator).

NR:

description
glucokinase regulatory protein

GO: NA

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007252055.3 True 2626 mRNA 0.42 19 24981376 24997874

Neighbor

gene id symbol gene type direction distance location
ptk2b LOC108428731,LOC108270138 coding upstream 98624 24849576 ~ 24882752 (+)
trnal-cag_10 NA coding upstream 153620 24827674 ~ 24827756 (+)
LOC103046279 NA coding upstream 155276 24814910 ~ 24826100 (+)
LOC103033951 LOC108428726 coding upstream 167567 24807926 ~ 24813809 (+)
LOC103034484 LOC107576683 coding upstream 175991 24799032 ~ 24805385 (+)
LOC103039108 NA coding downstream 461 24998335 ~ 25008777 (+)
xkr6 xkr6,xkr6a,LOC108269486,LOC107693112 coding downstream 47839 25045713 ~ 25071105 (+)
enpp4 enpp4 coding downstream 89729 25087603 ~ 25095143 (+)
clic5 clic5,LOC105909474,LOC103355727 coding downstream 100165 25098039 ~ 25109750 (+)
mcm8 mcm8,LOC107594086,LOC107678783 coding downstream 669825 25667699 ~ 25683838 (+)
G83307 NA non-coding upstream 48837 24931919 ~ 24932539 (+)
G83295 NA non-coding upstream 87737 24893243 ~ 24893639 (+)
G83180 NA non-coding upstream 141248 24838530 ~ 24840128 (+)
G83167 NA non-coding upstream 208583 24771882 ~ 24772793 (+)
G83123 NA non-coding upstream 338721 24642392 ~ 24642655 (+)
G83354 NA non-coding downstream 130086 25127960 ~ 25187909 (+)
G83438 cdc5l,LOC107594083,LOC107552094 non-coding downstream 363853 25361727 ~ 25367281 (+)
G83440 cdc5l,LOC106599718 non-coding downstream 372377 25370251 ~ 25387590 (+)
G83441 NA non-coding downstream 380697 25378571 ~ 25379291 (+)
G83446 NA non-coding downstream 466026 25463900 ~ 25464253 (+)
LOC111193228 NA other upstream 45190 24934164 ~ 24936186 (+)
ephx2 ephx2,LOC107733988,LOC107692411,LOC107653762 other upstream 56561 24895894 ~ 24924815 (+)
G82853 tulp4,LOC108428686,LOC107589648,LOC107734174,LOC107692724,LOC107742753,LOC107653590 other upstream 839144 24139389 ~ 24142232 (+)
G82811 psma3,LOC107729246,LOC107725600 other upstream 1007401 23909682 ~ 23973975 (+)
timm9 timm9,LOC107729247,LOC107693171,LOC107689314 other upstream 1103606 23875439 ~ 23877770 (+)
c9h8orf74 NA other downstream 32123 25029997 ~ 25034121 (+)
supt3h supt3h other downstream 163044 25160918 ~ 25329482 (+)
LOC103033015 LOC108423550,LOC108270308 other downstream 921683 25919557 ~ 25975283 (+)
G83602 NA other downstream 1237624 26235498 ~ 26253602 (+)
c9h14orf132 csgr16h14orf132,LOC108423442,LOC108269530,LOC108413331,LOC107582175 other downstream 1277127 26275001 ~ 26305383 (+)

Expression


Co-expression Network