LOC103021856 (bmp2,LOC108414145,LOC108270435)



Basic Information


Item Value
gene id LOC103021856
gene name bmp2,LOC108414145,LOC108270435
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 25718474 ~ 25724909 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007252060.3
AAGGCTTTATAtgtaagctgtattttttttgcttctttttaggagagataatGGATCATGAAGGGAGAGGAGGGAATTTCATCAGTCATCTCATGTGTTGGATGGACCTGTACCGTTTCAACCACTGGGAACCCGAGCACCACACCATTATTAATCCTTATTTGACAGCATGGATAGGGTGGTGtttgattttctttcttttttttttcttccttcttttcttctttgctCGCTGTGTTCATTCGTGACATCACTGAGCCACTAAAAGCCACATGGGCAgaaggagagaggaagagaaggagagagagtgtcAGTGAGAACAGTGCGCACACCAGACTCCACcaagctctctctttctctctctatctgtctatagGAGGAAAACCAGACCTTCTGCTGCTCTTCTGACTTGACTTCAGGAGGTCCATGCGTTTGGGAAGCTCTCAGAGATGGATGTTTTGGATGGAGGACCCTGAGATGGAACCAGCAATGATTTGAAAGGAAGTAACCAATTACTGGTGCTGGGCAGCTGAGTTCTGAAGAGTTTGGAGTTCTTCTGCTGGACTTTCTCCTCTGGAGCTAGCAGTGCGTGCACGTAGTTAGGGCACGCGCGTACGCACACACGTTTACGCGCGCATACTGCATACACCCACCACAGCACTCAAGGTCTCAAAACACAGTTGGACTCGATTGGACAAGGTGGTGAAGGTAGACTACAACTTCTGGTACAATCTGGATTGATTCTTCAGTGGAGGCTTCTACATCTTATCTTCCTCTACTGATGGACAGACTGCGAGTGCTTGGTTAGAACCTGCTGAGGAGGTTCTCCAGTTCTTTATCTGGGACTATGACTTAGGGTCCCAACCGTCTACGATACGCTTGCGTTTTAACGTCCAGCAGACGTGAGCAGGATGAGGTCCAACTTTAGAAGCTAGAAGaagaataataagaagaaggacataaaggaggaggaggacccACAGTGACGGACATGGCTAAGTGGTACCGGAGACGCCAAGTGGACGCGCGCCTCTGCCCGTGCCCGTGTGATTAAGCGCCACCAGCCCCCAGGTCTTGACCGACCGGGCGCGcgcctggctggctggctggctgggtGACCATGCGCTCCGCCGCGCTGCGCCGCGCGCTGcccctcctgctgctgctactggCTTACGCGCGTCTCGGGGGCTCCGCGGGGCTCGTGCCCGAGCCGGGCCGCAGGAGATACGCTGCGCCCTTGTCGCAGGACACCCTCAGCACCTTCGAGGCGCGACTCCTCAGCCTCTTCGGCCTCAAGCAGAGGCCCACCCCCAGCAGATCCGCCGTGGTTCCGCGCTACATGCTGGACCTGTTCACTGCGTACTCCGCCAACGCGGAGCCAAAGCACGGCGCGAGCAGGCGCGCGCTCGGGAGAGAGTCCGAGAAGTCCGCCAGCCGCGCGAACACCATAAGAAGCTTTCACCATGATGAATCTACAGAGCAGCTGTTGAGTCATGGCAGAAAGACGACTCAAAGGTTCCTCTTCAATCTGAGCTCCATCCCTGGAGAGGAGTTTGTCACTTCAGCCGAGCTGAGGATTTACAGGGAGCAGGTCATGGCGGCCACCAatagcaggagcagcagcaacagcagcagcctcGCTGGGCGCCATCGCATTAACATCTATGAGATCATGAAGCCTGGGCGTCCTTTGAAAGAGCCCATTACGAGACTCCTAGACACCAGGTTGGTGCAGCACAGCCTGAGCAAGTGGGAGAGCTTTGACGTAAGTCCGGCCGTCTCGCGGTGGACTGCCGAGGACCACGCCAACCACGGCTTTGTGGTGGAAGTGGTTCACCCGGAAGACGCAGACGGGGACTACAAGAAGCACGTCCGAGTCAGCAGATCGCTGCATGACAGCGAGGACTCGTGGCCACAGATGAGGCCTCTGCTGGTGACGTTCAGCCACGACGGGAAAGGACATGTGCTCCACAGCCGGCAGAAGCGGCAAGCGAGGATCAACAAGCCGAAGAAGAAGCACAAAGCCAACTGTAGGAGGCATTCCCTCTATGTGGACTTCAGCGACGTGGGCTGGAATGACTGGATAGTGGCCCCTCCAGGTTACCACGCCTTTTACTGCCAAGGAGAATGCCCCTTCCCTTTGGCAGACCACCTCAACTCCACCAACCACGCGATAGTACAGACGCTGGTGAACTCAGTGAACACAAACATTCCCAAGGCCTGCTGCGTGCCCACAGACCTGAGCCCCGTGTCCCTGCTCTACCTGGACGAGTACGAGCGGGTGATCCTGAAAAACTACCAGGACATGGTGGTGGAAGGCTGTGGGTGCCGCTGATGGACCTTAAgcagagacttttttttttgcgaagacACTTTATGACCCAGTACTACACTTTTATTTATGCTAaagtaaaaacacatattttggaaACAAagtatataaagctatatttatgTCCATTAatgggaaaataaatatttttaattggagtTCAGCTAATGTATTTTTCTGATGTACATTTCAACTAGTACAGTTCCGCATATGAAGTATACAGctcagattttttgtttttgtatttatttctagCATAACCACTTTTAGGGAatagtttaaatagtttatatatctatttatgtGTACtcaaagcaaaaatatatatacatatagatgtGTAAAACATCCACAACACACCGTACCACCATAGATTGGTTTATGTGTCTCCTATCATTTCTAGAGTGGAAAGCAAGGCTTGTGTATTGTGAGTTGATGAAGATTTAAACCTAATGTTAAGCGTTTCAGTGACAGTCCCATctgccttaattttttttagtgtcACATGAAGCACTGAATAGGTTGGATTTCCAGagagagattaagcctagtcctagacTCTAGACCTAGTATCTCTTCCAGTGGAGAATCCCCATTCACTGTGCTGTATGCTCTgcgactaggcttaatccctgtctgggaaaccagTCCAATTGGTTCAGTTAGTTGAGTAATCCAAAAGCATGCACTCCAGTTGGGCCTTTCCTGCAGTGAGAAGCAGTGGTGAATGTGAATGCACTTATCTAGAAGCAATGTGACAGGTAGTTGACACTGAATGCTCAGGAACTTTGGAACTGTTGGTGTGCGTGAGGTCTACAGTGCGAGCCTATGAAATCTATCAATAGCCTTACAGACAGTTACTATATGTCCTTCTCATTCTGATGCATGGGTTTCCCAAAGGCTAATCCATTCCCCTTTATagacccaatcccatttctcaaTTGTAACCAACCCCTTGTTTTCACTCTTAAGTGTTGAAATCCTCCCTCTAAGAAAAGGGACACTGTGATACGTTGTCAAAACTGTTAGCGATGCTCTGAAGGCAACCCTGTCACCTGTTTATGGCCACTCCTTATTCATTTGTGATAGGGAGCTGAAGTTAGCTAGACATTCACTATTTTTTGTTCAGCTAATTTGCCTGTTCCACCGTAAATCATGCAGGAGCCGCAGTTGTAACTGAATGTAActgctgcatcatttaaggtggaatgtgaAATGTATCTGAACTATACTAGCAATGTTTATTCTTGTTAATAAGAAAGGGTGGTTATCATATTTTTGAACAAAGAAAGCACAACATTGGTGGGTCTCTTCGGTCACTTGTGCAGCCATCTTGCCTGTGGATTTTTTATTGTAACAAATTGTTTGGAAGAAAAATCAGGAGggccataaataaataaatgtagccACAATGCTTCACCCTACTCCCCTATCCCAACGAGAATTGGAGCTCCCTAAACCCCTAGGTGTGATTGCACAAAGTGAaagggtaagtggtagggcaaAAGTTTGAAATGTGTTTGGGCCATAGTGAAGTCTTAGTAAAGCC

Function


symbol description
bmp2 Enables several functions, including BMP receptor binding activity; co-receptor binding activity; and phosphatase activator activity. Involved in several processes, including regulation of cellular biosynthetic process; regulation of signal transduction; and transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within several processes, including animal organ development; positive regulation of cellular metabolic process; and regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Located in cell surface; extracellular space; and intracellular membrane-bounded organelle. Part of BMP receptor complex. Implicated in bone disease (multiple); hemochromatosis type 1; otosclerosis; prostate cancer; and tooth agenesis. Biomarker of prostate cancer and prostate carcinoma.

NR:

description
bone morphogenetic protein 2

GO:

id name namespace
GO:0040007 growth biological_process
GO:0005576 extracellular region cellular_component
GO:0008083 growth factor activity molecular_function

KEGG:

id description
K21283 BMP2; bone morphogenetic protein 2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007252060.3 True 3884 mRNA 0.49 2 25718474 25724909

Neighbor


gene id symbol gene type direction distance location
gdf3 gdf3 coding upstream 1028 25715058 ~ 25717446 (+)
crls1 crls1,LOC107663140,LOC107738554,LOC107678734,LOC103476593 coding upstream 27580 25684805 ~ 25690894 (+)
mcm8 mcm8,LOC107594086,LOC107678783 coding upstream 34636 25667699 ~ 25683838 (+)
clic5 clic5,LOC105909474,LOC103355727 coding upstream 608724 25098039 ~ 25109750 (+)
enpp4 enpp4 coding upstream 623331 25087603 ~ 25095143 (+)
LOC103033987 plcb1,LOC103033987,LOC108423552,LOC107663155,LOC107678738 coding downstream 110231 25835140 ~ 25916844 (+)
LOC103041814 LOC108423416 coding downstream 603892 26328801 ~ 26330956 (+)
LOC103041516 NA coding downstream 607018 26331927 ~ 26335823 (+)
LOC103041211 LOC103041211,LOC108423415 coding downstream 626222 26351131 ~ 26352435 (+)
LOC103030701 NA coding downstream 632870 26357779 ~ 26360746 (+)
G83456 NA non-coding upstream 181204 25517590 ~ 25537270 (+)
G83449 NA non-coding upstream 222814 25495158 ~ 25495660 (+)
G83446 NA non-coding upstream 254221 25463900 ~ 25464253 (+)
G83440 cdc5l,LOC106599718 non-coding upstream 330884 25370251 ~ 25387590 (+)
G83522 hao1 non-coding downstream 73551 25798460 ~ 25802452 (+)
LOC111193229 NA non-coding downstream 259772 25984681 ~ 25993012 (+)
G83601 NA non-coding downstream 510007 26234916 ~ 26235175 (+)
G83649 NA non-coding downstream 585800 26310709 ~ 26310948 (+)
G83661 NA non-coding downstream 614273 26339182 ~ 26339699 (+)
supt3h supt3h other upstream 388992 25160918 ~ 25329482 (+)
c9h8orf74 NA other upstream 684353 25029997 ~ 25034121 (+)
LOC111193228 NA other upstream 782288 24934164 ~ 24936186 (+)
ephx2 ephx2,LOC107733988,LOC107692411,LOC107653762 other upstream 793659 24895894 ~ 24924815 (+)
G82853 tulp4,LOC108428686,LOC107589648,LOC107734174,LOC107692724,LOC107742753,LOC107653590 other upstream 1576242 24139389 ~ 24142232 (+)
LOC103033015 LOC108423550,LOC108270308 other downstream 194648 25919557 ~ 25975283 (+)
G83602 NA other downstream 510589 26235498 ~ 26253602 (+)
c9h14orf132 csgr16h14orf132,LOC108423442,LOC108269530,LOC108413331,LOC107582175 other downstream 550092 26275001 ~ 26305383 (+)
LOC103031022 LOC103031022,LOC108423548 other downstream 596276 26321185 ~ 26327338 (+)
spata7 NA other downstream 667981 26392890 ~ 26399267 (+)

Expression



Co-expression Network