ttc8 (ttc8,LOC106591546)


Basic Information

Item Value
gene id ttc8
gene name ttc8,LOC106591546
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 28079573 ~ 28085275 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007257365.3
TTATCCAACACGCATGCGCCTAGCTTACGTTACCGGGGTAACGCCAAGCTTGAAGCTTAGCTAAAACAGCATTAGCCAGCGCACAGGCTAGTTATTATCAGGCGGGTATTTACAGGCGTCTCTGTAGAAATGGAGGTGACTTTATCCATGGACCCACTCTTTTTAGCGTGGAGCTATTTTAGAAGACGAAAGTTCCAGAAATGTTCGGATATTTGCACAAAGGTGTTGGAAGACAGTCCTTACGACCAGgaACATGATACACCACTCCATATTTCTGAGGCGGCTTGGAGTCTGAAGACAAGAGCTGTGACTGAGATGGTGTACATTGATGAGGTGGAAGTGGATCAGGAGGGGATTGCAGAAATAATGTTGGATGAAAGTTCCATTGCTCAGGTGGCACGCCCTGGAACATCACTTAGACTCCCTGGAACAAGTCATGGGGGAGGACCTACTCCAGCTGTCAGgcCAATGACCCAATCAGGACGCCCCATCACAGGATTTGTAAGGCCCAGCACTCAGTCTGGTAGACCAGGGACCATGGAGCAAGCCATCAGAACTCCTCGCACAgcaaacactgcccgcccagtCACTAGTTCCTCTGGAAGATTTGTCAGATTGGGCACGGCTTCCATGCTCACAAATCCAGATGGACCTTTCATAAACTTATCCAGGTTAAATTTGGCAAAGTATTCCCAGAAACCAAATTTATCTAAGacCTTATTTGAATACATCTTTCATCATgaaaatgatgtaaaaaatGCATTGGACCTAGCTGCTCTTGCCACTGAGCATGCCCAGTTCAAAGATTGGTGGTGGAAAGTTCAGCTGGGCAAATGTTATTACAGGCTTGGTTTGTATCGTGAAGCTGAGAAACAGTTTAGATCAGCCCTCAACCACCAAGAATTTGTAGATACATATCTCTACCTGGCAAAGGTATATCAGCGACTGGATCAGCCCATAACTGCCCTAAACCTCTTCAAACAAGGCCTGGATCATTTCCCAGGAGAGGTGACTTTGCTAACTGGAATCGCTCGGATTCATGAGGAGATGAATAACATCACTTCAGCCACAGAGTACTACAAAGATGTCTTAAAGCAGGACAATACACATGTGGAAGCCATTGCCTGCATTGGAAGTAACCATTTTTATACAGACCAACCAGAGATTGCCCTACGCTTCTACAGACGCTTGCTGCAGATGGGTGTGTACAACTGCCAGCTGTATAATAACCTGGGCCTGTGCTGCTTTTATGCTCAGCAGTATGACATGACATTGTCATCATTTGAAAGAGCATTAGCTCTGGTTTCCAGTGATGAGGAACAGGCAGACGTCTGGTATAATCTTGGACATGTTGCAGTGGGTATAGGTGACTTGCCTCTGGCCTATCAATGCTTTAAATTAGCTTTGGCTTTCAACAATGATCATGCTGAGGCTTATAACAATTTGGCAGCACTGGAGCTGAGGAAAGGCCGCATTGAGCAGGCAAAAGCTTTTCTACAGACAGCTGCTACTCTGGCCCCGCATATGTATGAGCCACATTATAACTTTGCTATACTATCGGATAAGgtGGGTGATCTTCAGAGTAGCTACATGGCTGCTCAGAAGTCTGAGGACGCCTTTCCTGAGCACGTGGACACGCAGCAGATGCTGAAGAGCCTCAGGCACCACTTTGCTGTACTTTAAAAGAGTAATGGAATAGAAGACCACATTAACCTCATGTTTAGagatgtttatagagtc
>XM_007257366.3
TATCCAACACGCATGCGCCTAGCTTACGTTACCGGGGTAACGCCAAGCTTGAAGCTTAGCTAAAACAGCATTAGCCAGCGCACAGGCTAGTTATTATCAGGCGGGTATTTACAGGCGTCTCTGTAGAAATGGAGGTGACTTTATCCATGGACCCACTCTTTTTAGCGTGGAGCTATTTTAGAAGACGAAAGTTCCAGAAATGTTCGGATATTTGCACAAAGGTGTTGGAAGACAGTCCTTACGACCAGGCGGCTTGGAGTCTGAAGACAAGAGCTGTGACTGAGATGGTGTACATTGATGAGGTGGAAGTGGATCAGGAGGGGATTGCAGAAATAATGTTGGATGAAAGTTCCATTGCTCAGGTGGCACGCCCTGGAACATCACTTAGACTCCCTGGAACAAGTCATGGGGGAGGACCTACTCCAGCTGTCAGgcCAATGACCCAATCAGGACGCCCCATCACAGGATTTGTAAGGCCCAGCACTCAGTCTGGTAGACCAGGGACCATGGAGCAAGCCATCAGAACTCCTCGCACAgcaaacactgcccgcccagtCACTAGTTCCTCTGGAAGATTTGTCAGATTGGGCACGGCTTCCATGCTCACAAATCCAGATGGACCTTTCATAAACTTATCCAGGTTAAATTTGGCAAAGTATTCCCAGAAACCAAATTTATCTAAGacCTTATTTGAATACATCTTTCATCATgaaaatgatgtaaaaaatGCATTGGACCTAGCTGCTCTTGCCACTGAGCATGCCCAGTTCAAAGATTGGTGGTGGAAAGTTCAGCTGGGCAAATGTTATTACAGGCTTGGTTTGTATCGTGAAGCTGAGAAACAGTTTAGATCAGCCCTCAACCACCAAGAATTTGTAGATACATATCTCTACCTGGCAAAGGTATATCAGCGACTGGATCAGCCCATAACTGCCCTAAACCTCTTCAAACAAGGCCTGGATCATTTCCCAGGAGAGGTGACTTTGCTAACTGGAATCGCTCGGATTCATGAGGAGATGAATAACATCACTTCAGCCACAGAGTACTACAAAGATGTCTTAAAGCAGGACAATACACATGTGGAAGCCATTGCCTGCATTGGAAGTAACCATTTTTATACAGACCAACCAGAGATTGCCCTACGCTTCTACAGACGCTTGCTGCAGATGGGTGTGTACAACTGCCAGCTGTATAATAACCTGGGCCTGTGCTGCTTTTATGCTCAGCAGTATGACATGACATTGTCATCATTTGAAAGAGCATTAGCTCTGGTTTCCAGTGATGAGGAACAGGCAGACGTCTGGTATAATCTTGGACATGTTGCAGTGGGTATAGGTGACTTGCCTCTGGCCTATCAATGCTTTAAATTAGCTTTGGCTTTCAACAATGATCATGCTGAGGCTTATAACAATTTGGCAGCACTGGAGCTGAGGAAAGGCCGCATTGAGCAGGCAAAAGCTTTTCTACAGACAGCTGCTACTCTGGCCCCGCATATGTATGAGCCACATTATAACTTTGCTATACTATCGGATAAGgtGGGTGATCTTCAGAGTAGCTACATGGCTGCTCAGAAGTCTGAGGACGCCTTTCCTGAGCACGTGGACACGCAGCAGATGCTGAAGAGCCTCAGGCACCACTTTGCTGTACTTTAAAAGAGTAATGGAATAGAAGACCACATTAACCTCATGTTTAGagatgtttatagagtc
>XM_022673098.1
AACCAACCTACCTTGTAGTTCGGAGTCCAGCACCTTTCCCTGCTCACACCCAAACCTAAACCTAGTAATTAAAAGTTGAAAATTGTATGTATAAGCAAGGATATCACAAAAGTATGCTGGACCAGAACTAAAGAACTGTGTCCTAGTCCCTGTCCTCCAAACACCCCACTCCCCACTGCTACCCAAAGCCTACCTTTAGGTGTAGTAGTCAGACAGACCCCTAGAAAACCCAACCAATCCACCTGTATGAATCACTCCCACTCCGTCCTCGACTCCTAATATAGTAGAAAGGCGGCTTGGAGTCTGAAGACAAGAGCTGTGACTGAGATGGTGTACATTGATGAGGTGGAAGTGGATCAGGAGGGGATTGCAGAAATAATGTTGGATGAAAGTTCCATTGCTCAGGTGGCACGCCCTGGAACATCACTTAGACTCCCTGGAACAAGTCATGGGGGAGGACCTACTCCAGCTGTCAGgcCAATGACCCAATCAGGACGCCCCATCACAGGATTTGTAAGGCCCAGCACTCAGTCTGGTAGACCAGGGACCATGGAGCAAGCCATCAGAACTCCTCGCACAgcaaacactgcccgcccagtCACTAGTTCCTCTGGAAGATTTGTCAGATTGGGCACGGCTTCCATGCTCACAAATCCAGATGGACCTTTCATAAACTTATCCAGGTTAAATTTGGCAAAGTATTCCCAGAAACCAAATTTATCTAAGacCTTATTTGAATACATCTTTCATCATgaaaatgatgtaaaaaatGCATTGGACCTAGCTGCTCTTGCCACTGAGCATGCCCAGTTCAAAGATTGGTGGTGGAAAGTTCAGCTGGGCAAATGTTATTACAGGCTTGGTTTGTATCGTGAAGCTGAGAAACAGTTTAGATCAGCCCTCAACCACCAAGAATTTGTAGATACATATCTCTACCTGGCAAAGGTATATCAGCGACTGGATCAGCCCATAACTGCCCTAAACCTCTTCAAACAAGGCCTGGATCATTTCCCAGGAGAGGTGACTTTGCTAACTGGAATCGCTCGGATTCATGAGGAGATGAATAACATCACTTCAGCCACAGAGTACTACAAAGATGTCTTAAAGCAGGACAATACACATGTGGAAGCCATTGCCTGCATTGGAAGTAACCATTTTTATACAGACCAACCAGAGATTGCCCTACGCTTCTACAGACGCTTGCTGCAGATGGGTGTGTACAACTGCCAGCTGTATAATAACCTGGGCCTGTGCTGCTTTTATGCTCAGCAGTATGACATGACATTGTCATCATTTGAAAGAGCATTAGCTCTGGTTTCCAGTGATGAGGAACAGGCAGACGTCTGGTATAATCTTGGACATGTTGCAGTGGGTATAGGTGACTTGCCTCTGGCCTATCAATGCTTTAAATTAGCTTTGGCTTTCAACAATGATCATGCTGAGGCTTATAACAATTTGGCAGCACTGGAGCTGAGGAAAGGCCGCATTGAGCAGGCAAAAGCTTTTCTACAGACAGCTGCTACTCTGGCCCCGCATATGTATGAGCCACATTATAACTTTGCTATACTATCGGATAAGgtGGGTGATCTTCAGAGTAGCTACATGGCTGCTCAGAAGTCTGAGGACGCCTTTCCTGAGCACGTGGACACGCAGCAGATGCTGAAGAGCCTCAGGCACCACTTTGCTGTACTTTAAAAGAGTAATGGAATAGAAGACCACATTAACCTCATGTTTAGagatgtttatagagtc

Function

symbol description
ttc8 Acts upstream of or within several processes, including Kupffer's vesicle development; animal organ development; and establishment of pigment granule localization. Predicted to be part of BBSome. Used to study ciliopathy. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome; Bardet-Biedl syndrome 8; and retinitis pigmentosa 51. Orthologous to human TTC8 (tetratricopeptide repeat domain 8).

NR:

description
PREDICTED: tetratricopeptide repeat protein 8 isoform X1

GO:

id name namespace
GO:0001755 neural crest cell migration biological_process
GO:0046907 intracellular transport biological_process
GO:0032402 melanosome transport biological_process
GO:0070121 Kupffer's vesicle development biological_process
GO:0051877 pigment granule aggregation in cell center biological_process
GO:0060026 convergent extension biological_process
GO:0001947 heart looping biological_process
GO:0005622 intracellular anatomical structure cellular_component

KEGG:

id description
K16781 TTC8, BBS8; tetratricopeptide repeat protein 8

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007257365.3 False 1740 mRNA 0.46 15 28079573 28085275
XM_007257366.3 False 1709 mRNA 0.46 14 28079574 28085275
XM_022673098.1 True 1752 mRNA 0.46 14 28080695 28085275

Neighbor

gene id symbol gene type direction distance location
LOC103040475 LOC108423515,LOC108269951 coding upstream 6979 28010514 ~ 28072594 (+)
LOC103041699 prima1,LOC108423434,LOC108270468 coding upstream 158400 27906826 ~ 27921173 (+)
LOC103042002 LOC108423517 coding upstream 184590 27881028 ~ 27894983 (+)
ddx24 ddx24 coding upstream 209600 27860194 ~ 27869973 (+)
LOC103042318 LOC103042318,LOC108423523 coding upstream 220832 27855741 ~ 27858741 (+)
ndc80 ndc80 coding downstream 9088 28094363 ~ 28101936 (+)
nek9 nek9 coding downstream 18641 28103916 ~ 28113291 (+)
acyp1 acyp1 coding downstream 33746 28119021 ~ 28121707 (+)
LOC103036705 fos,LOC108423428,LOC107702235 coding downstream 42118 28127393 ~ 28130890 (+)
jdp2 jdp2,jdp2a,LOC107701522,LOC107589793,LOC107702236 coding downstream 49038 28134313 ~ 28150109 (+)
G84001 NA non-coding upstream 156215 27923069 ~ 27923358 (+)
LOC111193235 LOC103459065 non-coding upstream 233607 27831977 ~ 27845966 (+)
G83972 NA non-coding upstream 374692 27704254 ~ 27704881 (+)
LOC107197843 NA non-coding upstream 464006 27604237 ~ 27615567 (+)
G83826 NA non-coding upstream 810342 27268958 ~ 27269231 (+)
G84164 NA non-coding downstream 216458 28301733 ~ 28360989 (+)
LOC111193142 NA non-coding downstream 243500 28328775 ~ 28331408 (+)
G84219 NA non-coding downstream 288673 28373948 ~ 28374517 (+)
G84264 NA non-coding downstream 502121 28587396 ~ 28587954 (+)
G84280 NA non-coding downstream 620618 28705893 ~ 28723051 (+)
LOC103044189 LOC108423527,LOC107677688 other upstream 247989 27824256 ~ 27831584 (+)
fam98b NA other upstream 257362 27815805 ~ 27822211 (+)
fermt2 fermt2 other upstream 1302085 26727823 ~ 26777488 (+)
spata7 NA other upstream 1680306 26392890 ~ 26399267 (+)
LOC103031022 LOC103031022,LOC108423548 other upstream 1752235 26321185 ~ 26327338 (+)
LOC107197841 NA other downstream 884989 28970264 ~ 28970839 (+)
LOC103045392 NA other downstream 914227 28999502 ~ 29025114 (+)
LOC111193240 NA other downstream 955704 29040979 ~ 29041607 (+)
LOC111193135 NA other downstream 957942 29043217 ~ 29043739 (+)
LOC107197844 NA other downstream 986616 29071891 ~ 29078898 (+)

Expression


Co-expression Network