hmgcl (hmgcl,LOC107583590,LOC107721118,LOC107670875,LOC107715992)


Basic Information

Item Value
gene id hmgcl
gene name hmgcl,LOC107583590,LOC107721118,LOC107670875,LOC107715992
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 8552448 ~ 8566788 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007257567.3
CTCTgcggtatctctctctctgtagagtAAACAGTAGAGGAGGACATGGCGGCCGTGCTAATGAGGTTTGTCCCCAGTTCTCTTGGACCAGCTGCGGTCCAGAGGTCTCTGTCCTTCAGCTCCAGCGCTGCCGTCCGAGCCaTCAGCTTGTCTCCAACAAAACCTCTCCCAGAAAAGGTGAAGATTGTTGAAGTGGGACCCAGAGATGGACTACAGAATGAGAAGACTCTTGTCCCTGCTGAGGTGAAGATCCGTCTAATTGACATGCTGTCGGAGGCGGGGCTTCCTGTCGTTGAGGCCACTAGTTTTGTGTCACCTAAATGGGTCCCTCAGATGGCAGATCAGGAGGAGGTGATGCGTGGAATTCACAGGAAGAACGGAGTTAATTACCCAGTACTGACCCCCAACCTGAAGGGCTACAGAGCAGCTgtaAATGCCGGAGCAAAGGAGGTTGCAATATTTGGAGCTGCCTCTGAGCTCTTCAGTAAGAAGAACATTAACTGCTCAGTGGAGGAGAGTCTACAGCGCTTTGAGGAAGTGATGACAGCAGCCAAACAGGATGGAATACCTGTGAGAGGATATGTGTCTTGCGTACTTGGCTGCCCATATGAAGGGAAGGTATCTGCAGCTAAAGTTGCGGAAGTTGCTAAGCGGCTCTACTCTATGGGTTGCTATGAGATTTCCCTGGGCGACACCATTGGCGTTGGTACTCCAGGAGGCATGATCGAGATGCTGGAGGCGGTGAAGAAAGAGGTGCCTGTGCAAGCCCTAGCTGTGCACTGCCACGATACCTATGGACAGGCACTTGCTAACATCCTGGTAGCTCTGCAGAACGGCGTGAGTGTTGTGGATTCCTCAGTGTCTGGATTAGGTGGATGCCCATATGCCCAGGGGGCTTCTGGCAATGTGGCTACAGAGGACGTTGTGTACATGCTCCACGGACTAGGCATTCACACTGGAGTGGATCTACACAAGCTGATGGATGCCGGCTCGTATATCTGCCGTTCCCTCAACAGAAGGACGAGTTCCAAAGTCGCACAAGCCGCCTGTAAACTGTGATTTGCAATACAAattgggtgtgtttgtgtttgactctctttctttctcactatGTCTCCTGTTGGTTTCCTATGGGCATGTGcatttctctcgctctctgtctctttgcTTTATGGCAAAGGAAGCCCAGACATGGCTGATGGGCCTTCTGAGACACTGCTAAGGCACGGATGCAGCACTGTGTGCTTTGTTCTGAAGGCTGTGGAACGATTTTCCTGACTTTCCTTCTCCTCTCATAATGGAAGGAAGTCAGGAAGAACGTATGAATTAGCTGGTCCACTGTTTGCTTTTGGATGGGAGCCTAAATGCACAGTGGCACTGGAGGCCCTTCTGATGAATTAGCCtgtaattatatatacacacagacacacacacactcttcatctctgtttgtttgtcagGACGGAGTGTATGACGACTGTTTCTCGTCTTAATCGCCCAGCCTTGACAAGCCCCGTGTGTACAAGAGCCTGAGAGTTTCTCGTGAAGATACAGAAGCAAGCATCGAAACCCCTTTATTCTAGTGCCTTGTTTTCACGCCGGCTAAACGGCTCGCATGCCAATTTTAGCCTCCCGACTAATCTCCCGAGTGCTTCTTGGAAAGTTAAATATTGAGCTTTGGAGCTGGAAGGTTCAAACAACACCCACAGCACATGTGGAGCAGGGCCTGTCAGCTACAGAAGCATCTCAAAATCAATGTAACCCAGATGTGAGAGGGGTTTGGTTGATGGGATGGATGACCCAGTTATCcctggttcacactacacaactttgaGTAGTCAGGTCGTTGTTCTGTTCACACTGTATTGCTGGTTGTGAAGTATTTGTCAACACGAGGTCACTAGTTACACGATTTTTAACTCAGACTCATCGGGCTGTGCTTCAATAACACATTTTGTGATGTGAACACTCAGGAACTAAACGCACACAGAAACTATTGATGCCATGCTTCCCTCTCTCTACATGATCCTATTTACTGTTTGTAGTCACTGCCCTTGTCTCACAGTCACTGACTGGtctagatattaaacctgctagatcTTTGCCTGGCTTCTTTGATTCAGCTTGGTGAGTGTATTTTAGCAGTTCACACAACACGGCAAGTGATCTCTGATTTAAAAGCAGCAATCAGAGCAGAGATCGGcttgaaaacttgaaaaaaaaaaaa
>XM_022672670.1
CTCTgcggtatctctctctctgtagagtAAACAGTAGAGGAGGACATGGCGGCCGTGCTAATGAGGTTTGTCCCCAGTTCTCTTGGACCAGCTGCGGTCCAGAGGTCTCTGTCCTTCAGCTCCAGCGCTGCCGTCCGAGCCaTCAGCTTGTCTCCAACAAAACCTCTCCCAGAAAAGGTGAAGATTGTTGAAGTGGGACCCAGAGATGGACTACAGAATGAGAAGACTCTTGTCCCTGCTGAGGTGAAGATCCGTCTAATTGACATGCTGTCGGAGGCGGGGCTTCCTGTCGTTGAGGCCACTAGTTTTGTGTCACCTAAATGGGTCCCTCAGATGGCAGATCAGGAGGAGGTGATGCGTGGAATTCACAGGAAGAACGGAGTTAATTACCCAGTACTGACCCCCAACCTGAAGGGCTACAGAGCAGCTgtaAATGCCGGAGCAAAGGAGGTTGCAATATTTGGAGCTGCCTCTGAGCTCTTCAGTAAGAAGAACATTAACTGCTCAGTGGAGGAGAGTCTACAGCGCTTTGAGGAAGTGATGACAGCAGCCAAACAGGATGGAATACCTGTGAGAGGATATGTGTCTTGCGTACTTGGCTGCCCATATGAAGGGAAGGTATCTGCAGCTAAAGTTGCGGAAGTTGCTAAGCGGCTCTACTCTATGGGTTGCTATGAGATTTCCCTGGGCGACACCATTGGCGTTGGTACTCCAGGAGGCATGATCGAGATGCTGGAGGCGGTGAAGAAAGAGGTGCCTGTGCAAGCCCTAGCTGTGCACTGCCACGATACCTATGGACAGGCACTTGCTAACATCCTGGTAGCTCTGCAGAACGGCGTGAGTGTTGTGGATTCCTCAGTGTCTGGATTAGGTGGATGCCCATATGCCCAGGGGGCTTCTGGCAATGTGGCTACAGAGGACGTTGTGTACATGCTCCACGGACTAGGCATTCACACTGGAGTGGATCTACACAAGCTGATGGATGCCGGCTCGTATATCTGCCGTTCCCTCAACAGAAGGACGAGTTCCAAAGTCGCACAAGCCGCCTGTAAACTGTGATTTGCAATACAAattggaCTCGTGTCCTGAAAGAGTCAGTGTTGATTACAGTACTAATAGCAAGCCTTGCACTGGTAATGCATTTCCTTgtaaaattgggagaaaatttgaaattttaattgattttgttatttataatgttctgttaataatggaaaatatagtgattatttaagaataaatgtaaataaatgtttggcgttattttaaattgatatatatatttttaataaaatctgattgacttatgaattattcatcCGCTATTTTATGACGCAATAAAAGTTGAAAAAGGAAATGAA

Function

symbol description
hmgcl Predicted to enable hydroxymethylglutaryl-CoA lyase activity. Predicted to be involved in ketone body biosynthetic process; leucine catabolic process; and lipid metabolic process. Predicted to be located in peroxisome. Is expressed in liver. Human ortholog(s) of this gene implicated in amino acid metabolic disorder. Orthologous to human HMGCL (3-hydroxy-3-methylglutaryl-CoA lyase).

NR:

description
PREDICTED: hydroxymethylglutaryl-CoA lyase, mitochondrial isoform X1

GO:

id name namespace
GO:0004419 hydroxymethylglutaryl-CoA lyase activity molecular_function

KEGG:

id description
K01640 E4.1.3.4, HMGCL, hmgL; hydroxymethylglutaryl-CoA lyase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007257567.3 True 2227 mRNA 0.48 8 8552448 8563360
XM_022672670.1 False 1361 mRNA 0.47 9 8552448 8566788

Neighbor

gene id symbol gene type direction distance location
LOC103031442 LOC103359616 coding upstream 45287 8469601 ~ 8507161 (+)
erich1 NA coding upstream 109893 8415207 ~ 8442555 (+)
ppie ppie coding upstream 743498 7802220 ~ 7808950 (+)
LOC103024072 pabpc4,LOC107654874,LOC107716002 coding upstream 753189 7766569 ~ 7799259 (+)
LOC103024901 NA coding upstream 787771 7759849 ~ 7764677 (+)
trmt61b NA coding downstream 56613 8623401 ~ 8634193 (+)
greb1 greb1,LOC107719472,LOC107697724,LOC107590942 coding downstream 1199378 9766166 ~ 9819445 (+)
LOC103026171 LOC108413038 coding downstream 1675800 10242588 ~ 10252495 (+)
LOC103026492 NA coding downstream 1715877 10282665 ~ 10292293 (+)
LOC103026974 NA coding downstream 1762180 10328968 ~ 10336716 (+)
LOC111193184 NA non-coding upstream 14067 8536432 ~ 8538381 (+)
G78810 NA non-coding upstream 39801 8512397 ~ 8512647 (+)
G78806 NA non-coding upstream 41624 8476510 ~ 8510824 (+)
G78797 NA non-coding upstream 67187 8463424 ~ 8485261 (+)
G78808 NA non-coding upstream 72861 8478006 ~ 8479587 (+)
G78824 NA non-coding downstream 25957 8592745 ~ 8593288 (+)
G78834 NA non-coding downstream 83007 8649795 ~ 8672419 (+)
G79035 NA non-coding downstream 725770 9292558 ~ 9293030 (+)
G79041 NA non-coding downstream 806868 9373656 ~ 9373883 (+)
G79042 NA non-coding downstream 807296 9374084 ~ 9375551 (+)
G78817 gale,LOC107583591,LOC107721820,LOC107583106 other upstream 2480 8529854 ~ 8549968 (+)
G78818 NA other upstream 14766 8535916 ~ 8537682 (+)
fam167b LOC108433301,LOC101067225 other upstream 823447 7656307 ~ 7729001 (+)
G78671 LOC107659230,LOC107583602 other upstream 944784 7594707 ~ 7607664 (+)
LOC103024862 LOC108430185 other upstream 1680043 6857354 ~ 6872405 (+)
spata17 NA other downstream 928661 9495449 ~ 9554725 (+)
LOC103029457 LOC108441045 other downstream 1316218 9883006 ~ 9955038 (+)
LOC103025860 pcgf5b,LOC103025860,LOC108430201,LOC107583544,LOC107553461,LOC107715951,LOC107670868 other downstream 1971291 10538079 ~ 10556868 (+)
fam98a fam98a,LOC107583540,LOC107744493,LOC107670808 other downstream 2234569 10801357 ~ 10814914 (+)
G79654 NA other downstream 2987894 11554682 ~ 11555139 (+)

Expression


Co-expression Network