lck (lck,LOC107716006,LOC107654872,LOC107721256,LOC108270195)


Basic Information

Item Value
gene id lck
gene name lck,LOC107716006,LOC107654872,LOC107721256,LOC108270195
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 7682841 ~ 7744462 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022672660.1
ACGCACCACATGTGTGTGAAGCTGAAGCAGCGCTGCACCAGTCTTATCTGCGCACCTTTCCTTCACAGGTCTAGAAGCTTCTCTAGAAGCGTTTCGGATCCTGTAAAACCGTGGATATAAGGATGAGGACCAGTCCCACCCATCCATGAAATCTGAGGACCACCTGAGACCACCAGCAGTGATACTATAACAGACACCATGGGGAACTGTGGCTCCTACGACTCAGACGGTGAATTCTCCTACCACCCCGACGATGAACTCTGCGAACACTGCAACTGCCCTATTCCCCCAGGAAACCAGACGCAGTATAATGACAAATTTCCATTCAACTCCAACTACACACCTCCCCCAACTTCCCCATTACCAGATAACTTGGTGGTGGCCATGCACAGCTATCAGCCATCCCACAGTGATGACCTGGGCTTCGAAAAAGGAGAGAAGATGAAGATCCTCTTAGAAGATGATCCAGAATGGTACATGGCAGAGTCTCTGTCTACGGGACAGAGGGGCTACATTCCACGCAACTTTGTGGGCAAACTCAACAGCATGGAGACTGAAGCCTGGTTCTTTAAGAACCTCTCCAGAAATGATGCCATGAGGCATCTGCTGGCTCCAGGAAACACACAAGGTTCCTTCCTGATCCGAGAGAGCGAGACCACGCCAGgtagtttctctctgtctgtgcgcGATTTAGACCACACGGATGGTGATGTCATCAAGCACTACAGAATCCGCAACCTGGACGCCGGTGGCTTCTACATCACTGGCAAGATCTCCTTCAGCACACTGTCTGAGCTGGTCAGACATTACTCCCGAGAGGCTGATGGTCTGTGTACACGGCTGATTAAGCCATGTCAGACGAGCATGCCACAGAGGCCGTGGTGGCAGGATGAGTGGGAGGTTCCCCGTGAATCTCTGAAGCTGGAGAGGAGGCTGGGCCAGGGCCAGTTTGGGGAGGTGTGGATGGGCATGTACAATAATAGCAGAAGGGTGGCTATTAAGAGCCTGAAGACTGGCACCATGTCCATCGGGGCCTTCCTGGCCGAAGCCAACCTGATGAAGACGCTCCAGCACCCGCGCCTTGTCCGCCTGTTCGCAGTGGTGACGCAGGAGCCCATCTATATCATCACTGAGTACATGGAGAACGGCAGTCTGGTGGATTTTCTGAAGACTCCTGAGGGAGCAAGTCTGCAGACCAACACCTTGATTGATATGGCATCTCAGGTGGCAGATGGAATGGCCTACATTGAGCATAAGAACTACATCCACCGAGACCTGAGAGCCGCTAACATCCTGGTATCTGACACGCTCATCTGCAAGATCGCTGACTTCGGCCTGGCTCGCCTCATTGAGAACGATGAATACACAGCCAGGGAAGGTGCAAAGTTCCCCATCAAATGGACGGCTCCTGAAGCCATAAACTACGGCACCTTCTCCATCAAATCGGACGTGTGGTCTTTCGGAATCCTGCTGACCGAGATTGTGACCTATGGCAGAATCCCTTACCCAGGCATGTCCAATCCAGAAGTGATCCAGAACCTGGAGAACGGATACCGCATGCCCTGTCCAGACAACTGCCCCGATGGCCTCTACAACGTCATGACCGCGTGCTGGACTGAAAACCCAGAGAACCGGCCAACCTTTGAGTACCTGCGCGGTGTGCTGGAGGATTTCTCCACCGCCACAGAGGGCCAGTACCAGGAGCAGCCCTGCTGAGATCCATCAGTACCCCTCCTCCGCCTCCTACCAGAACTCTTAGGATTCTTTCTCAGTTCTTCAGTGGCACTATATGTGCATCATCCtgaaacatttctcacaaaaacaaaactgtatatattaaCAGCACCAATAGTATGTTTAAGGATGTTGTGCTTATATGACGGGATTAATTATGATTCTACAAATACTGTTGCCTGCAGTCTGCTCAGGAATGCTTCTACACgggaataattcataatattaACATCACTATACATATGTGTAGGGTaccatgtaaaaatgttttgttgttgttgtttattttagcttttattttttaaatctacacAACTCTTTCATCCATTATCTCCTCGTCATCTTTACCATCTTTACTTTTTACCATAGAACTGTAATTACTTTGATATGAAAATTGATACGAAATTGTGAATGTTCTTGTTTGAGGAGCTGTGGTGGCAGCGGACCCTTACTCtgaatttcattttgttttcatcTTTTCGCTTGACGTCCAATTGCGTGTGAGCTGAGAAGTGACAGTCCACACCACCAACTAGATTGGACCAGCCAGAACTGAGTTCTGAGTCAGAACTCACAtctagaaatatttaaaatgtgtggtATTAACTGATCCAACTAATTACtggctcattgctatcttaaaccctgccaaaattctttttttttttttatgccctccgcctgcattgtttaaatagcaacagagcttgtaaatatatctacagCAATGGCTGTGGTTGTCTGGATTGAGGTTTGTTCAGGTATATTTCTGGTaagttgctatcttggcaacagtaaacacaggtgcaccactgactgaaagctACCTAGACAACATCTGACACCAACAGTCAGATGCTCTTTGCATCTGAACTCCCGAAATCTGGTCACTGAACAGAAGCTTGATTGTTTGATGTTGGATGCTGTACCATTGTGGCATTATCTTGTCgtatcttatttctttttgaattctttgatttttttttcttctcatgtTCCTCATGATGctgaataaaattaaaggtCATTGTACTGTAATTGGACACGACATTTTTTGCATAtctaaattaagttaaatttagctaagttaagtaaacaaaactgtaattctaaaataaaagaaaaagtcaaa

Function

symbol description
lck Predicted to enable non-membrane spanning protein tyrosine kinase activity and signaling receptor binding activity. Predicted to be involved in T cell differentiation; cell surface receptor signaling pathway; and innate immune response. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in cytosol. Predicted to be extrinsic component of cytoplasmic side of plasma membrane. Is expressed in T cell; head kidney; lymphocyte; pro-T cell; and thymus. Human ortholog(s) of this gene implicated in immunodeficiency 22. Orthologous to human LCK (LCK proto-oncogene, Src family tyrosine kinase).

NR:

description
tyrosine-protein kinase Lck

GO:

id name namespace
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0005524 ATP binding molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function

KEGG:

id description
K05856 LCK; lymphocyte cell-specific protein tyrosine kinase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022672660.1 True 2866 mRNA 0.46 13 7682841 7744462

Neighbor

gene id symbol gene type direction distance location
rtn4ip1 rtn4ip1,LOC107659252 coding upstream 239120 7410429 ~ 7443721 (+)
rab3gap2 rab3gap2,LOC107659254 coding upstream 370549 7284848 ~ 7312292 (+)
LOC103030509 ppp1cb,LOC103030509,LOC100692170 coding upstream 405738 7255113 ~ 7277103 (+)
LOC111193178 NA coding upstream 438089 7226490 ~ 7244752 (+)
hhat hhat coding upstream 609333 6974915 ~ 7073508 (+)
LOC103024901 NA coding downstream 15387 7759849 ~ 7764677 (+)
LOC103024072 pabpc4,LOC107654874,LOC107716002 coding downstream 22107 7766569 ~ 7799259 (+)
ppie ppie coding downstream 57758 7802220 ~ 7808950 (+)
erich1 NA coding downstream 670745 8415207 ~ 8442555 (+)
LOC103031442 LOC103359616 coding downstream 725139 8469601 ~ 8507161 (+)
LOC103026041 NA non-coding upstream 53949 7626997 ~ 7628892 (+)
G78668 NA non-coding upstream 130473 7547456 ~ 7552368 (+)
G78646 NA non-coding upstream 293152 7389465 ~ 7389689 (+)
LOC103029755 NA non-coding upstream 336391 7343193 ~ 7346450 (+)
G78603 iars2,LOC107654863,LOC107582886,LOC107715938 non-coding upstream 361591 7319609 ~ 7321250 (+)
G78725 NA non-coding downstream 2559 7747021 ~ 7748434 (+)
G78728 NA non-coding downstream 6952 7751414 ~ 7758200 (+)
G78753 NA non-coding downstream 240119 7984581 ~ 7986723 (+)
G78760 NA non-coding downstream 250165 7994627 ~ 7996807 (+)
G78786 NA non-coding downstream 538478 8282940 ~ 8332434 (+)
G78671 LOC107659230,LOC107583602 other upstream 75177 7594707 ~ 7607664 (+)
LOC103024862 LOC108430185 other upstream 810436 6857354 ~ 6872405 (+)
LOC103025550 qkia,LOC108413473,LOC107721620,LOC107590898,LOC107697705,LOC103376478,LOC108269894 other upstream 2152786 5452115 ~ 5530055 (+)
G78111 pole2 other upstream 3384657 4289507 ~ 4298184 (+)
g2e3 g2e3 other upstream 3857969 3765780 ~ 3824872 (+)
G78817 gale,LOC107583591,LOC107721820,LOC107583106 other downstream 785392 8529854 ~ 8549968 (+)
G78818 NA other downstream 791454 8535916 ~ 8537682 (+)
spata17 NA other downstream 1750987 9495449 ~ 9554725 (+)
LOC103029457 LOC108441045 other downstream 2138544 9883006 ~ 9955038 (+)
LOC103025860 pcgf5b,LOC103025860,LOC108430201,LOC107583544,LOC107553461,LOC107715951,LOC107670868 other downstream 2793617 10538079 ~ 10556868 (+)

Expression


Co-expression Network