plk4 (plk4,LOC107703461,LOC107561682,LOC107664465,LOC107718857,LOC107586821)


Basic Information

Item Value
gene id plk4
gene name plk4,LOC107703461,LOC107561682,LOC107664465,LOC107718857,LOC107586821
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 18568668 ~ 18579571 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022672858.1
atgtttgacGTGATTCAGTCCTTAATGCAAAACCTAACTAACAACGAGAGATGCGCAATAAATGGAAAAATACTTAGGACGTCCGGGGATCTTTCAATCGAGGACTTTAAGGTTCTCACCTTACTTGGTAAGGGATCCTTTGCATGTGTTTACAGAGCTAAGTCTGTGAACACGGGCTTGGAGGTGGCGATCAAAATGATTGATAAGAAAGCCATGCACAAAGCTGGCATGGTCCAACGTGTCATTAATGAGGTAGAGATTCAGTGTCGGTTAAAACATCCGTCAATACTGGAGCTGTACAATTACTTTGAGGACAGTAATTATGTGTACCTGGTGCTGGAGATGTGCCATAATGGGGAGATGAGCCGCTATCTGAAAGACAGGAAGAAACCTTTCACAGAAGAAGAAGtgAGACTCTTCATGCATCAGATTGTAAAGGGCATGCTGTATCTGCACACCCATGGAATTATGCACAGGGATCTGACCCTATCTAACCTGCTGCTCAGCAGCAGCATGAACATTAAGATAGCAGACTTTGGTCTCGCCACGCAGCTCAAACTGCCCAGCGAGAAGCACTTCACCATGTGCGGCACACCTAACTACATCTCTCCTGAGGTAGCCACACGCAGTGCCCACGGCCTGGAGTCTGATGTCTGGTCACTGGGCTGCATGTTCTACGCCTTCCTAACAGGCAGGCCTCCTTTCGATACGGACACTGTCAAACAGACCCTCAACAAAGTGGTTTTAGGAGAGTATCAGATGGCCACTCACGTGTCAGCTGAGGCTCAGGATCTGATTCGGCAGCTGTTACAGAAGGACCCTACTCTCAGACCCAGCCTCTCAGCGGTGCTGGACCACCCTTTTATGACCCAGAGTGGACCCACTGCAAGCAAAGATTCTGGCGCTAGTGAGGGAGGCTCTATAGATAGTGGCATAGCAACAATATCTACAGCTTCCAACACCACGAGCAGCAGCAACAGCCGTCTCCACAGGAAAGCCCGGCAGGTGATTGGCCAGGCCTTACCGAACCGCATGGTGCCGCTCCCCAGCCAGTCGCAGCACTCCACTAGCTCCAGTTTTAAGAGTGGGCAAGACTGGCAGCCACATCCATCAGGCAATATGAGGCTTCTTGTGGATGCAGACCGTGAAAGGCCCCATTCTCGATACCTGAGACGTGCCCACTCCTCTGATCGGTCAGGTGCTGGATTTAGCCATGCTAGGCAGGAGGTGGAGTTGGAGCGATGCCACTCAGAGGAGGTGATTCCAGGCTCCAATCGGATCTTCCCATCAGCTTCAAGCTACCGGGAAACTCCTCATGGCTATTCTGAACATGGGCGGCTTCCTTCCCCCCCGGTCAAACAGCCTGCAAACCCTGGGTCCTCCTTCTCTACTCCAGCACATCCAGTCAGACTGCAGATGGCTGAATCAGAGACACAGCCATGGTTCAGTACAGATGGGTCTTTTAAGAGGCCAGCAGATGTCAGCGGCCACAGCAGCAGTGGAAGTTTTCATTCTGGGCGGGAAGCATTGGAGGCTGTACCTTCCTGCAGTGACAGACCAATGCTGAGAGGAACCAGTGGTCTTCCTCCAAACTCATACAGCCATTCATCCTTGCAGAACAATCCAAGACCCTGCAGGGGGGGTGGACTGGGAGGGGGGCAATTGCCTGCATCTAAGGACTGTCTAGATGTACAGGGTGCACCTCTTTCCAAGAGCAAAGCTAATGTGGTAAAGGAGAAGAAGAGTCCATTTCCTCCTCTGTGTGCAGCCAGACTGAAGCCTATCAGACAAAAGACCAAAAATGCTGTGGTCAGCATCCTAGACACAGGAGAAGTGTGTATGGAGCTTTTGAAAGGCCAGGGAACCCAGGAGAGGGTCAAAGAAGTGCTCAGGATATCCTGCGATGGATCCATGgtcacTGTGTACCAGCCCAACGATGGTAAAGGGTTCCCTGTCTTGGACCATCCACCTTCTCCCCCAGAAGATATTTTTATATGCAGTTATGAGGATTTGCCAGAGAAATACTGGAAGAAGTATCAGTATGCTACTAAGTTTGTTCAGTTGGTGAAGTCAAAGACTCCTAAAGTAACCTTGTACACCAAGTTTGCCAAATGCATGTTGATGGAGAACTCCCCTAATGCAGACCTGGAAGTGTGCTTTTAtgatgGTGCCAAAACCCACAGGTCGGGTGATCAGGTACGAGTGGTGGAGAAAAGTGGAAAGTCATACACGATGAAAGGGGATATTGGCCTGAGTGGTGTCAGTCCTGAGTGCAGACTCTACATGGAGCTTGCAGATGAGgGTCACAGAATGTGTCTCTCTTTGGAGGCTGCAATAAGTGCTGAGGAGCAGCGTAGTGCCAGAGCTACACCTTTCTTCCCCATCACTATTGGCAGGAGGCCAACTAACCCTACCTCCTCATTCCCTGCAACACAGCCTGCTTCTGATCAGAGTCCTGCAATGCCTGCTGAGGTGGCTCAGGTGTGCCTGAGTCCGCCCCAGGCACCCCATATCACCCCTTCTATGATTTCCTACAATGGGTCTGATTTCACAACAGCCAGTCTGGCCAAAGGCAGCTCACCCCAGTCAGCCAAAGATGGGCATAATGTCAATACTGGAAAAGTACTTAAGTCCATCTTTGTACCCAACATTGGTTGGGCCTCACAGCTAACAACTGGAGAAGTGTGGGTTCAGTTTAATGATGGATCCCAGCTAGTGGTCCAAGCAGGGGTCTCCTGTATCACGTTCACCTCCCCAGAAGGACACATCACAAGGTATAAGGAGAATGAGAAGCTACCAGAGCTGGTAAAGGAGAAACTGCATTGCCTGTCCTCCATCCTAAGCCTCCTGGCCAGTCCAGCTGTACGACGCTGAGCAGCAGAAATAGCTTGGAGAAAAGGACCATAGTGAAAAGCacttctttatttcagtaaaaaaaaatctctttcaaaaaaatgcattaagtatctgtaaatacattttaaaacgtTGTACAGATTGTTCCAAGATtatgaaaattatatatttttatgttgtacAGTATGGATTTTTTTGTAGTGGTTGTTATGAGCATTTggattgtgtaaaaaaaatatttttttactcagcaAAAAGGTTACTCCAGAGCTGCAGTGAAATGTCATGGGCAAAAATGCAAGTAATAAACATCGTCTGCTGGCTAAACCTC
>XM_022672859.1
TCCGGTTGCGTCGTCACGATTCTAACGGGCGGACTTTTCAAAATGGAGGAAAAGCAAATATTTTGGAGGGGAACAAAAGTACAacgtttaaatgtgttttacgTGGATTATGTGGATAAAGCGCAGCTGTTTATGaaatagaaaagggtttttatgACGGCGGAGCACTGTTTAGGCCCCGCGGATGATATGAAGTGAAGATGAGTGTCTCAATCGGGGACAAAATTGAGGACTTTAAGGTTCTCACCTTACTTGGTAAGGGATCCTTTGCATGTGTTTACAGAGCTAAGTCTGTGAACACGGGCTTGGAGGTGGCGATCAAAATGATTGATAAGAAAGCCATGCACAAAGCTGGCATGGTCCAACGTGTCATTAATGAGGTAGAGATTCAGTGTCGGTTAAAACATCCGTCAATACTGGAGCTGTACAATTACTTTGAGGACAGTAATTATGTGTACCTGGTGCTGGAGATGTGCCATAATGGGGAGATGAGCCGCTATCTGAAAGACAGGAAGAAACCTTTCACAGAAGAAGAAGtgAGACTCTTCATGCATCAGATTGTAAAGGGCATGCTGTATCTGCACACCCATGGAATTATGCACAGGGATCTGACCCTATCTAACCTGCTGCTCAGCAGCAGCATGAACATTAAGATAGCAGACTTTGGTCTCGCCACGCAGCTCAAACTGCCCAGCGAGAAGCACTTCACCATGTGCGGCACACCTAACTACATCTCTCCTGAGGTAGCCACACGCAGTGCCCACGGCCTGGAGTCTGATGTCTGGTCACTGGGCTGCATGTTCTACGCCTTCCTAACAGGCAGGCCTCCTTTCGATACGGACACTGTCAAACAGACCCTCAACAAAGTGGTTTTAGGAGAGTATCAGATGGCCACTCACGTGTCAGCTGAGGCTCAGGATCTGATTCGGCAGCTGTTACAGAAGGACCCTACTCTCAGACCCAGCCTCTCAGCGGTGCTGGACCACCCTTTTATGACCCAGAGTGGACCCACTGCAAGCAAAGATTCTGGCGCTAGTGAGGGAGGCTCTATAGATAGTGGCATAGCAACAATATCTACAGCTTCCAACACCACGAGCAGCAGCAACAGCCGTCTCCACAGGAAAGCCCGGCAGGTGATTGGCCAGGCCTTACCGAACCGCATGGTGCCGCTCCCCAGCCAGTCGCAGCACTCCACTAGCTCCAGTTTTAAGAGTGGGCAAGACTGGCAGCCACATCCATCAGGCAATATGAGGCTTCTTGTGGATGCAGACCGTGAAAGGCCCCATTCTCGATACCTGAGACGTGCCCACTCCTCTGATCGGTCAGGTGCTGGATTTAGCCATGCTAGGCAGGAGGTGGAGTTGGAGCGATGCCACTCAGAGGAGGTGATTCCAGGCTCCAATCGGATCTTCCCATCAGCTTCAAGCTACCGGGAAACTCCTCATGGCTATTCTGAACATGGGCGGCTTCCTTCCCCCCCGGTCAAACAGCCTGCAAACCCTGGGTCCTCCTTCTCTACTCCAGCACATCCAGTCAGACTGCAGATGGCTGAATCAGAGACACAGCCATGGTTCAGTACAGATGGGTCTTTTAAGAGGCCAGCAGATGTCAGCGGCCACAGCAGCAGTGGAAGTTTTCATTCTGGGCGGGAAGCATTGGAGGCTGTACCTTCCTGCAGTGACAGACCAATGCTGAGAGGAACCAGTGGTCTTCCTCCAAACTCATACAGCCATTCATCCTTGCAGAACAATCCAAGACCCTGCAGGGGGGGTGGACTGGGAGGGGGGCAATTGCCTGCATCTAAGGACTGTCTAGATGTACAGGGTGCACCTCTTTCCAAGAGCAAAGCTAATGTGGTAAAGGAGAAGAAGAGTCCATTTCCTCCTCTGTGTGCAGCCAGACTGAAGCCTATCAGACAAAAGACCAAAAATGCTGTGGTCAGCATCCTAGACACAGGAGAAGTGTGTATGGAGCTTTTGAAAGGCCAGGGAACCCAGGAGAGGGTCAAAGAAGTGCTCAGGATATCCTGCGATGGATCCATGgtcacTGTGTACCAGCCCAACGATGGTAAAGGGTTCCCTGTCTTGGACCATCCACCTTCTCCCCCAGAAGATATTTTTATATGCAGTTATGAGGATTTGCCAGAGAAATACTGGAAGAAGTATCAGTATGCTACTAAGTTTGTTCAGTTGGTGAAGTCAAAGACTCCTAAAGTAACCTTGTACACCAAGTTTGCCAAATGCATGTTGATGGAGAACTCCCCTAATGCAGACCTGGAAGTGTGCTTTTAtgatgGTGCCAAAACCCACAGGTCGGGTGATCAGGTACGAGTGGTGGAGAAAAGTGGAAAGTCATACACGATGAAAGGGGATATTGGCCTGAGTGGTGTCAGTCCTGAGTGCAGACTCTACATGGAGCTTGCAGATGAGgGTCACAGAATGTGTCTCTCTTTGGAGGCTGCAATAAGTGCTGAGGAGCAGCGTAGTGCCAGAGCTACACCTTTCTTCCCCATCACTATTGGCAGGAGGCCAACTAACCCTACCTCCTCATTCCCTGCAACACAGCCTGCTTCTGATCAGAGTCCTGCAATGCCTGCTGAGGTGGCTCAGGTGTGCCTGAGTCCGCCCCAGGCACCCCATATCACCCCTTCTATGATTTCCTACAATGGGTCTGATTTCACAACAGCCAGTCTGGCCAAAGGCAGCTCACCCCAGTCAGCCAAAGATGGGCATAATGTCAATACTGGAAAAGTACTTAAGTCCATCTTTGTACCCAACATTGGTTGGGCCTCACAGCTAACAACTGGAGAAGTGTGGGTTCAGTTTAATGATGGATCCCAGCTAGTGGTCCAAGCAGGGGTCTCCTGTATCACGTTCACCTCCCCAGAAGGACACATCACAAGGTATAAGGAGAATGAGAAGCTACCAGAGCTGGTAAAGGAGAAACTGCATTGCCTGTCCTCCATCCTAAGCCTCCTGGCCAGTCCAGCTGTACGACGCTGA

Function

symbol description
plk4 Predicted to enable protein serine/threonine kinase activity. Acts upstream of or within centriole assembly; cilium assembly; and developmental growth. Predicted to be located in centriole; deuterosome; and nucleolus. Predicted to be active in cytoplasm; microtubule cytoskeleton; and nucleus. Is expressed in brain; eye; nervous system; and pronephros. Used to study ciliopathy. Human ortholog(s) of this gene implicated in microcephaly and chorioretinopathy 2. Orthologous to human PLK4 (polo like kinase 4).

NR:

description
serine/threonine-protein kinase PLK4-like

GO:

id name namespace
GO:0098535 de novo centriole assembly involved in multi-ciliated epithelial cell differentiation biological_process
GO:0046601 positive regulation of centriole replication biological_process
GO:0006468 protein phosphorylation biological_process
GO:0098536 deuterosome cellular_component
GO:0005814 centriole cellular_component
GO:0005730 nucleolus cellular_component
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function

KEGG:

id description
K08863 PLK4; polo-like kinase 4

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022672858.1 True 3187 mRNA 0.49 16 18569530 18579571
XM_022672859.1 False 3002 mRNA 0.50 16 18568668 18579258

Neighbor

gene id symbol gene type direction distance location
hspa4l hspa4l,LOC107561683,LOC107586823 coding upstream 1014 18551021 ~ 18567654 (+)
mrpl35 mrpl35 coding upstream 39979 18523754 ~ 18528689 (+)
LOC103034157 LOC108425685,LOC108269929,LOC107719399,LOC107664487,LOC107586877,LOC106610886,LOC106580683 coding upstream 58199 18503191 ~ 18510469 (+)
zfyve28 zfyve28 coding upstream 71629 18481679 ~ 18497039 (+)
LOC103032442 LOC108425610 coding upstream 128579 18436289 ~ 18440089 (+)
LOC103031945 itpk1,itpk1b,LOC108435758,LOC107664466,LOC107561681,LOC106597151 coding downstream 1298 18580869 ~ 18632555 (+)
eml5 eml5,si:dkey-1f12.3,LOC108435760 coding downstream 54598 18634169 ~ 18704075 (+)
npc2 npc2 coding downstream 128841 18708412 ~ 18712887 (+)
atg2b atg2b,LOC107738272,LOC107664023 coding downstream 136967 18716538 ~ 18749129 (+)
msh4 msh4 coding downstream 171122 18750693 ~ 18764580 (+)
G81558 chmp3,LOC107732730,LOC107586824 non-coding upstream 18461 18545469 ~ 18550207 (+)
G81539 NA non-coding upstream 67957 18447388 ~ 18500711 (+)
G81540 NA non-coding upstream 69790 18475117 ~ 18498878 (+)
G81547 NA non-coding upstream 97097 18470407 ~ 18471571 (+)
G81537 LOC108425611 non-coding upstream 125957 18441069 ~ 18442711 (+)
G81600 isca2 non-coding downstream 125244 18704815 ~ 18706282 (+)
G81602 gskip,LOC107731910,LOC107561679 non-coding downstream 134634 18714205 ~ 18717199 (+)
G81701 NA non-coding downstream 286105 18865676 ~ 18865988 (+)
G81705 NA non-coding downstream 351585 18931156 ~ 18937144 (+)
G81708 NA non-coding downstream 361837 18941408 ~ 18941814 (+)
LOC103033848 LOC108435752 other upstream 47721 18511622 ~ 18520947 (+)
LOC103035760 rtkn2,rtkn2a other upstream 99033 18460123 ~ 18469635 (+)
cmpk2 cmpk2 other upstream 531594 18027307 ~ 18037074 (+)
G80857 NA other upstream 2985337 15563987 ~ 15583331 (+)
LOC111193203 NA other upstream 3364881 15174535 ~ 15203787 (+)
G81704 NA other downstream 350667 18930238 ~ 18930754 (+)
G81761 NA other downstream 1086165 19665736 ~ 19666047 (+)
G81763 NA other downstream 1093556 19673127 ~ 19673638 (+)
ralgapa2 ralgapa2,LOC107687934 other downstream 2941336 21520907 ~ 21673438 (+)
G82488 NA other downstream 3778073 22357644 ~ 22358135 (+)

Expression


Co-expression Network