LOC103035447 (vegfa,vegf,LOC106584182)


Basic Information

Item Value
gene id LOC103035447
gene name vegfa,vegf,LOC106584182
gene type misc
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035905.1
NCBI id CM008308.1
chromosome length 42966623
location 32199183 ~ 32218762 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022673183.1
TACAGCCAGCGagcgagacagacagagagaaacagagagagagaaacagagaaacagacagagagaagaaaagataaAGGAAGAAGCGTGGAAGAAGCCGTGGAGACGCGTTTGGTTTTGGGCCCCTGCGCGCGCGGattggatcttttttttttggcagcatGAAATGCTGATTAGTGCCCCCCTCGTCTGCGTGCGTAACGCCGTGGTGCGCATTGTCGTCTCGCCGCGGCCGCTGCTGCTGGGAGCTCTACGagaaacttaacttttttaCGCGTTTTAACGATTTTAACGCGTTTTACGCTTTTGTATTTCTGTTCCCCCGCGTTATTTATTGACCATTGATCGGCCTTTTCCACTGTGGATTGTAAGAAAGTGATCAGAAGGAGGACGCACGCGCCGAGCTTGTGTGGATTTCCCTCTTTTTCCATTCCTTTACGCCtttttccttttattctgaGGATTTTCTCGCAGGTGCCTCTTGACTGGGGCAGTATGGGAGTGCTActctgaccccccccccccccccccctcctcttcttcttcttctcctcctcctcctccttcttctcctcagTGTCACGGGTTTTGCTCCActgtagagagaaagaagaggccTGTGATTCTCCCTGTTCCCTTCAAGACTTCACCTCCTTTAAACATATTTCCCTACGAACTTTTTTTGAGGGGGAAAAGCCAAAAAACATGAACTTTGGTGTCTATTCGCTGCACTTGGTTTTAGCAGCGCTGCTTCACGCGTCTGCACTGAAGGCAGCACACATACCTCCCAAAGACGGAGGGAAAAGCAAAAATGAAGtGGTTCCCTTTATGGATGTCTACACGAAAAGCCAGTGTAACACCCGGGAGGTTCTCGTAGACATCTTGCAGGAGTATCCGGACGATATAGAGTCCACCTACATCCCGTCCTGTGTAGTTCTCAACCGCTGTGCGGGCTGCTGCAACGATGAAGCGCTGGAGTGCGGCCCCAAGGAGACGCAAACCGTCACCATGGAGGTATTAAGAGTGAGGCAAGGTTTTGCACAACATAAATATCAGTTGAATTTCACAGAACATACAAAATGTGAATGCAGacCAAAACAAGAActcaaaacaaagaaagaaaaCCGCTGCGAGCCTTGCTCAGAGAGAAGGAAGCGCTTGTTTGTGCAGGACCCTCTCACCTGCACATGTTCCTGCAAATTCACACAGTTACACTGCAAGTCCAGGCAACTTGAGTTAAACGAACGAACTTGCAGATGTGACAAGCCAAGGAGATGATTGGACTTTGTATGTCAGACGTCGACGGACACTGAAATGTATGAAGGAATTCTTTCAAATGgcactttcttcttttttttcaaccTGTGGACCATACTGCATAACACGACTCcagaacacagagacagaggcaGGATAACC
>XM_022673184.1
ACAGCCAGCGagcgagacagacagagagaaacagagagagagaaacagagaaacagacagagagaagaaaagataaAGGAAGAAGCGTGGAAGAAGCCGTGGAGACGCGTTTGGTTTTGGGCCCCTGCGCGCGCGGattggatcttttttttttggcagcatGAAATGCTGATTAGTGCCCCCCTCGTCTGCGTGCGTAACGCCGTGGTGCGCATTGTCGTCTCGCCGCGGCCGCTGCTGCTGGGAGCTCTACGagaaacttaacttttttaCGCGTTTTAACGATTTTAACGCGTTTTACGCTTTTGTATTTCTGTTCCCCCGCGTTATTTATTGACCATTGATCGGCCTTTTCCACTGTGGATTGTAAGAAAGTGATCAGAAGGAGGACGCACGCGCCGAGCTTGTGTGGATTTCCCTCTTTTTCCATTCCTTTACGCCtttttccttttattctgaGGATTTTCTCGCAGGTGCCTCTTGACTGGGGCAGTATGGGAGTGCTActctgaccccccccccccccccccctcctcttcttcttcttctcctcctcctcctccttcttctcctcagTGTCACGGGTTTTGCTCCActgtagagagaaagaagaggccTGTGATTCTCCCTGTTCCCTTCAAGACTTCACCTCCTTTAAACATATTTCCCTACGAACTTTTTTTGAGGGGGAAAAGCCAAAAAACATGAACTTTGGTGTCTATTCGCTGCACTTGGTTTTAGCAGCGCTGCTTCACGCGTCTGCACTGAAGGCAGCACACATACCTCCCAAAGACGGAGGGAAAAGCAAAAATGAAGtGGTTCCCTTTATGGATGTCTACACGAAAAGCCAGTGTAACACCCGGGAGGTTCTCGTAGACATCTTGCAGGAGTATCCGGACGATATAGAGTCCACCTACATCCCGTCCTGTGTAGTTCTCAACCGCTGTGCGGGCTGCTGCAACGATGAAGCGCTGGAGTGCGGCCCCAAGGAGACGCAAACCGTCACCATGGAGGTATTAAGAGTGAGGCAAGGTTTTGCACAACATAAATATCAGTTGAATTTCACAGAACATACAAAATGTGAATGCAGacCAAAACAAGAActcaaaacaaagaaagaaaaATGTGACAAGCCAAGGAGATGATTGGACTTTGTATGTCAGACGTCGACGGACACTGAAATGTATGAAGGAATTCTTTCAAATGgcactttcttcttttttttcaaccTGTGGACCATACTGCATAACACGACTCcagaacacagagacagaggcaGGATAACC
>XR_002650383.1
GAGACTACAGCCAGCGagcgagacagacagagagaaacagagagagagaaacagagaaacagacagagagaagaaaagataaAGGAAGAAGCGTGGAAGAAGCCGTGGAGACGCGTTTGGTTTTGGGCCCCTGCGCGCGCGGattggatcttttttttttggcagcatGAAATGCTGATTAGTGCCCCCCTCGTCTGCGTGCGTAACGCCGTGGTGCGCATTGTCGTCTCGCCGCGGCCGCTGCTGCTGGGAGCTCTACGagaaacttaacttttttaCGCGTTTTAACGATTTTAACGCGTTTTACGCTTTTGTATTTCTGTTCCCCCGCGTTATTTATTGACCATTGATCGGCCTTTTCCACTGTGGATTGTAAGAAAGTGATCAGAAGGAGGACGCACGCGCCGAGCTTGTGTGGATTTCCCTCTTTTTCCATTCCTTTACGCCtttttccttttattctgaGGATTTTCTCGCAGGTGCCTCTTGACTGGGGCAGTATGGGAGTGCTActctgaccccccccccccccccccctcctcttcttcttcttctcctcctcctcctccttcttctcctcagTGTCACGGGTTTTGCTCCActgtagagagaaagaagaggccTGTGATTCTCCCTGTTCCCTTCAAGACTTCACCTCCTTTAAACATATTTCCCTACGAACTTTTTTTGAGGGGGAAAAGCCAAAAAACATGAACTTTGGTGTCTATTCGCTGCACTTGGTTTTAGCAGCGCTGCTTCACGCGTCTGCACTGAAGGCAGCACACATACCTCCCAAAGACGGAGGGAAAAGCAAAAATGAAGtGGTTCCCTTTATGGATGTCTACACGAAAAGCCAGTGTAACACCCGGGAGGTTCTCGTAGACATCTTGCAGGAGTATCCGGACGATATAGAGTCCACCTACATCCCGTCCTGTGTAGTTCTCAACCGCTGTGCGGGCTGCTGCAACGATGAAGCGCTGGAGTGCGGCCCCAAGGAGACGCAAACCGTCACCATGGAGGTATTAAGAGTGAGGCAAGGTTTTGCACAACATAAATATCAGTTGAATTTCACAGAACATACAAAATGTGAATGCAGacCAAAACAAGAActcaaaacaaagaaagaaaaAAAACCCCGAAAGGGCAAAGGTCaaaagagaaaggcagagaggcTGAGAGGCGACGGGCCCCAGGCCCACAGCAGCGGGAGCACTCCTCTGCAGCCCGGCCCCGTGTGCCTCACGCTTGCGGCTCTGGTGTTAGAGCAATGCGTCTGGTTCTCCAGCTGCTGAGCGTTTGCTTCTCTCTTTGCCGACCGTACCGCTTGAGGCTGGTACGGGGTCGCGGCTCAGGGGCAGCAGGAGAGATGTGACAAGCCAAGGAGATGATTGGACTTTGTATGTCAGACGTCGACGGACACTGAAATGTATGAAGGAATTCTTTCAAATGgcactttcttcttttttttcaaccTGTGGACCATACTGCATAACACGACTCcagaacacagagacagaggcaGGATAACC
>XR_002650384.1
GAGACTACAGCCAGCGagcgagacagacagagagaaacagagagagagaaacagagaaacagacagagagaagaaaagataaAGGAAGAAGCGTGGAAGAAGCCGTGGAGACGCGTTTGGTTTTGGGCCCCTGCGCGCGCGGattggatcttttttttttggcagcatGAAATGCTGATTAGTGCCCCCCTCGTCTGCGTGCGTAACGCCGTGGTGCGCATTGTCGTCTCGCCGCGGCCGCTGCTGCTGGGAGCTCTACGagaaacttaacttttttaCGCGTTTTAACGATTTTAACGCGTTTTACGCTTTTGTATTTCTGTTCCCCCGCGTTATTTATTGACCATTGATCGGCCTTTTCCACTGTGGATTGTAAGAAAGTGATCAGAAGGAGGACGCACGCGCCGAGCTTGTGTGGATTTCCCTCTTTTTCCATTCCTTTACGCCtttttccttttattctgaGGATTTTCTCGCAGGTGCCTCTTGACTGGGGCAGTATGGGAGTGCTActctgaccccccccccccccccccctcctcttcttcttcttctcctcctcctcctccttcttctcctcagTGTCACGGGTTTTGCTCCActgtagagagaaagaagaggccTGTGATTCTCCCTGTTCCCTTCAAGACTTCACCTCCTTTAAACATATTTCCCTACGAACTTTTTTTGAGGGGGAAAAGCCAAAAAACATGAACTTTGGTGTCTATTCGCTGCACTTGGTTTTAGCAGCGCTGCTTCACGCGTCTGCACTGAAGGCAGCACACATACCTCCCAAAGACGGAGGGAAAAGCAAAAATGAAGtGGTTCCCTTTATGGATGTCTACACGAAAAGCCAGTGTAACACCCGGGAGGTTCTCGTAGACATCTTGCAGGAGTATCCGGACGATATAGAGTCCACCTACATCCCGTCCTGTGTAGTTCTCAACCGCTGTGCGGGCTGCTGCAACGATGAAGCGCTGGAGTGCGGCCCCAAGGAGACGCAAACCGTCACCATGGAGGTATTAAGAGTGAGGCAAGGTTTTGCACAACATAAATATCAGTTGAATTTCACAGAACATACAAAATGTGAATGCAGacCAAAACAAGAActcaaaacaaagaaagaaaaAAAACCCCGAAAGGGCAAAGGTCaaaagagaaaggcagagaggcTGAGAGGCGACGGGCCCCAGGCCCACAGCAGCGGGAGCACTCCTCTGCAGCCCGGCCCCGTGTGCCTCACGCTTGCGGCTCTGGTGTTAGAGCAATGCGTCTGGTTCTCCAGCTGCTGAGCGTTTGCTTCTCTCTTTGCCGACCGTACCGCTTGAGGCTGGTACGGGGTCGCGGCTCAGGGGCAGCAGGAGAGCCGCTGCGAGCCTTGCTCAGAGAGAAGGAAGCGCTTGTTTGTGCAGGACCCTCTCACCTGCACATGTTCCTGCAAATTCAC
>XR_002650385.1
ACATGAACTTTGGTGTCTATTCGCTGCACTTGGTTTTAGCAGCGCTGCTTCACGCGTCTGCACTGAAGGTAGGAGCACCCTGATgggGCAGCACACATACCTCCCAAAGACGGAGGGAAAAGCAAAAATGAAGtGGTTCCCTTTATGGATGTCTACACGAAAAGCCAGTGTAACACCCGGGAGGTTCTCGTAGACATCTTGCAGGAGTATCCGGACGATATAGAGTCCACCTACATCCCGTCCTGTGTAGTTCTCAACCGCTGTGCGGGCTGCTGCAACGATGAAGCGCTGGAGTGCGGCCCCAAGGAGACGCAAACCGTCACCATGGAGGTATTAAGAGTGAGGCAAGGTTTTGCACAACATAAATATCAGTTGAATTTCACAGAACATACAAAATGTGAATGCAGacCAAAACAAGAActcaaaacaaagaaagaaaaAAAACCCCGAAAGGGCAAAGGTCaaaagagaaaggcagagaggcTGAGAGGCGACGGGCCCCAGGCCCACAGCAGCGGGAGCACTCCTCTGCAGCCCGGCCCCGTGTGCCTCACGCTTGCGGCTCTGGTGTTAGAGCAATGCGTCTGGTTCTCCAGCTGCTGAGCGTTTGCTTCTCTCTTTGCCGACCGTACCGCTTGAGGCTGGTACGGGGTCGCGGCTCAGGGGCAGCAGGAGAGATGTGACAAGCCAAGGAGATGATTGGACTTTGTATGTCAGACGTCGACGGACACTGAAATGTATGAAGGAATTCTTTCAAATGgcactttcttcttttttttcaaccTGTGGACCATACTGCATAACACGACTCcagaacacagagacagaggcaGGATAACC

Function

symbol description
vegfa Enables several functions, including fibronectin binding activity; heparin binding activity; and signaling receptor binding activity. Involved in several processes, including positive regulation of cell migration; positive regulation of intracellular signal transduction; and positive regulation of macromolecule metabolic process. Acts upstream of or within several processes, including branching involved in blood vessel morphogenesis; positive regulation of endothelial cell proliferation; and regulation of nitric oxide mediated signal transduction. Located in several cellular components, including adherens junction; cell surface; and secretory granule. Implicated in several diseases, including autoimmune disease (multiple); gastrointestinal system cancer (multiple); hematologic cancer (multiple); hypertension (multiple); and reproductive organ cancer (multiple). Biomarker of several diseases, including artery disease (multiple); autoimmune disease (multiple); eye disease (multiple); inflammatory bowel disease (multiple); and respiratory system cancer (multiple).

NR:

description
PREDICTED: vascular endothelial growth factor A isoform X2

GO:

id name namespace
GO:0030097 hemopoiesis biological_process
GO:0007202 activation of phospholipase C activity biological_process
GO:0048793 pronephros development biological_process
GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis biological_process
GO:0051781 positive regulation of cell division biological_process
GO:0031334 positive regulation of protein-containing complex assembly biological_process
GO:0048844 artery morphogenesis biological_process
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation biological_process
GO:0001569 branching involved in blood vessel morphogenesis biological_process
GO:0001570 vasculogenesis biological_process
GO:0048010 vascular endothelial growth factor receptor signaling pathway biological_process
GO:0008016 regulation of heart contraction biological_process
GO:0003262 endocardial progenitor cell migration to the midline involved in heart field formation biological_process
GO:0051894 positive regulation of focal adhesion assembly biological_process
GO:0030878 thyroid gland development biological_process
GO:0008045 motor neuron axon guidance biological_process
GO:0043491 protein kinase B signaling biological_process
GO:0001938 positive regulation of endothelial cell proliferation biological_process
GO:0035477 regulation of angioblast cell migration involved in selective angioblast sprouting biological_process
GO:0035479 angioblast cell migration from lateral mesoderm to midline biological_process
GO:0005576 extracellular region cellular_component
GO:0005622 intracellular anatomical structure cellular_component
GO:0016020 membrane cellular_component
GO:0008201 heparin binding molecular_function
GO:0008083 growth factor activity molecular_function

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022673183.1 False 1419 mRNA 0.49 7 32199188 32218762
XM_022673184.1 False 1286 mRNA 0.48 6 32199189 32218762
XR_002650383.1 True 1529 misc_RNA 0.51 7 32199183 32218762
XR_002650384.1 False 1447 misc_RNA 0.52 7 32199183 32215147
XR_002650385.1 False 840 misc_RNA 0.51 7 32199891 32218762

Neighbor

gene id symbol gene type direction distance location
kpna5 kpna5,LOC107552832,LOC107711738,LOC107716841 coding upstream 349719 31835348 ~ 31849464 (+)
rwdd1 rwdd1,LOC107700695,LOC107587776,LOC107552826,LOC107704860 coding upstream 379331 31812267 ~ 31819852 (+)
mms22l mms22l coding upstream 439643 31712784 ~ 31759540 (+)
fbxl4 fbxl4,LOC107587770,LOC107716847 coding upstream 658268 31524951 ~ 31540915 (+)
faxc faxc coding upstream 696592 31480632 ~ 31502591 (+)
LOC103038892 NA coding downstream 201370 32420132 ~ 32425312 (+)
LOC103038371 NA coding downstream 208264 32427026 ~ 32430265 (+)
LOC103035585 LOC108423467 coding downstream 510357 32729119 ~ 32923000 (+)
LOC103035281 NA coding downstream 824083 33042845 ~ 33057697 (+)
c9h2orf71 NA coding downstream 842421 33061183 ~ 33071966 (+)
G85317 NA non-coding upstream 22422 32176539 ~ 32176761 (+)
G85316 NA non-coding upstream 27332 32171617 ~ 32171851 (+)
G85310 NA non-coding upstream 69770 32129099 ~ 32129413 (+)
G85304 NA non-coding upstream 113439 32085203 ~ 32085744 (+)
G85279 NA non-coding upstream 152373 32041867 ~ 32046810 (+)
G85315 NA non-coding downstream 102 32218864 ~ 32219936 (+)
G85335 NA non-coding downstream 57283 32276045 ~ 32276309 (+)
G85337 NA non-coding downstream 65378 32284140 ~ 32284478 (+)
G85338 NA non-coding downstream 71618 32290380 ~ 32290622 (+)
G85339 NA non-coding downstream 73260 32292022 ~ 32292429 (+)
G85189 NA other upstream 374795 31823586 ~ 31824388 (+)
LOC103034273 LOC103034273,LOC108415529 other upstream 393780 31749703 ~ 31805403 (+)
pnisr pnisr,LOC102782257 other upstream 729627 31454984 ~ 31469556 (+)
alg3 alg3,LOC107660011,LOC107730451,LOC107749127,LOC107557882,LOC107692886,LOC107600115 other upstream 1584121 30606757 ~ 30615062 (+)
LOC103025336 rhob,LOC103025336,LOC105888539,LOC105907285,LOC106607565 other upstream 2184003 29967550 ~ 30015180 (+)
LOC103037843 pnrc2,LOC108441235 other downstream 217455 32436217 ~ 32441318 (+)
G85740 zdhhc14 other downstream 2528052 34746814 ~ 34800377 (+)
tfb1m tfb1m,cldn20,LOC101886267,LOC107571061,LOC107675320,LOC107573130,LOC107728965,LOC108443299 other downstream 3069453 35288215 ~ 35339832 (+)
LOC111193254 NA other downstream 3418048 35636810 ~ 35658087 (+)
LOC111193255 NA other downstream 5265259 37484021 ~ 37503882 (+)

Expression


Co-expression Network