bcl11a (bcl11a,bcl11aa,LOC107666449,LOC107601892,LOC107743494,LOC107655449,LOC107559339)



Basic Information


Item Value
gene id bcl11a
gene name bcl11a,bcl11aa,LOC107666449,LOC107601892,LOC107743494,LOC107655449,LOC107559339
gene type misc
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035921.1
NCBI id CM008324.1
chromosome length 46505145
location 14722400 ~ 14780313 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>TU293854
CTATATCAAAAGAGAATCAAATGCAGCTGATCTGTCCTGAGGCGGAGTTTACCCAGAGCACAGAGGCTACTATAAAagtaacagaacaaaaacaaaaaaaggcaaaCGCGCCGGATCCGGACGAactgttggaaaaaaaatcGCAAGTGTCTCCACAGCTTTGAAACagtctgctttattttttaaaatgatttttgcagtgtaaatcTTGCTGTTTTCAGTGTGCTGCAGCTGAGAGCTGAGTGAGAGTGAGGCTTGTGATAGTGAGGGAGGGGGGTGGTATgggataggataggatagggTTGGGgtgttgtggtggtggtggtggtgtgatgTGTGCTGGGTGCTAGTGGGCGAGGGAGGAGGCGCCTTACAGCATATTTCCTTCCTCCAAGTGTCGCGTTTCTCCGCGGGCACCCGTCGCTCTGTGCCAAGCCATCAGTGAGCTGTAACTCagcctcacttttttttttttctttttttttttttcttctttttttccaccGTGGCTCTTCACAGCTCTTCAGGTCAAACGTAACTTGCATTGGGGAAAGGTTTaagattatatataaatatataatagagaACTTAAATATAGGAAAATGCACACTCATGTTCAATTCCTatgctaaaacacatttatgatctactttttttctgtatttctagaATGGTATTTGAATTAAATGTTCACCTAGTGTAGGCACTATAGTATTTATATTGAGGCTTGTATTTTTAACTGTTGCTTGTTCTCTCAAAAGGTATTATTGTACCTTTTTTGGtagtggaaaaaaacaacaagctgCCAcggtatatttttttaatttggcaggATAATATAGTACGaattatttgtatgtttaaaaaaaaatgaactgaaaaaaaatttcaataaaaaaacaactaaagtaTGTGGCATTGTATAAAAAGGAGGCCATCTAATGGTTTCCCCGAGGAGTCTTTTGCGAATGTCCACACTAGCTAAAACAGGTGGTTGTAcatatctttttttctgttctttttttagacTCTCCTCTTCTGCTGCCATTCTGTATGCAGTAATGCAAGCTGATGTTGGGTTCTTCTGTAGTGTGCTTCTCTGTCTTCTCACCTATCTCACCTGACTACATTCCAGCATCTTAAAGAGAACAAACTTCATATGCAGTAAATACCAGTACATAAATGAAAATCattcaaataaatgaattaaaaataatcaaagttttgcaggttttttgttttcattgccAAATACTAAATGGTGCTTTATATTTAGATTGGGATGACTTTCATATGcaaagcatatttaaaaatgaaatggaaATAATGGAAAGCCCGCTTGAGTTCATACTTTTTTGTAAATGGCAATGCGGAATATTTTGTTATCAGCCTTTTCTATTCCTGTTCTGAAAGCTGTTTGTTgtaacttgaacttgaactttaTCTTTTACAATGGGAGtcactatttattattacttaaatGCTCTGTTCAGAACGGAGACATGGAATGGAtcttttttggttttctttattttgtttttgttattgttgtttttctttgaaAATGACCAAAGGTCATTGACAACCTTTGCTTTTATTTGCTGTATTTGTTTCTGGTCTATGTTGAGTTTTATTGGAGAAACCACTGTCTGTGTTTTCTGGCAGTTGTCTGCATTATCCTGTTCACACACCCATTTTGTCCCTTTAttgaaaacaattaataaaaaaattaaagtatcaCTTTGTCGGTACAGTTTCTGTGGGGAGGTGGGTCtc
>XM_007252237.3
CACTCCCCGGCTTTGCCCTGCCCATGTTTTGTATGTCTGTGTCCATCCATCTCCTGACGTTCAAGTTCGCAGGGACGTCACGTCCGCACTTGAACTTGCAGCTCAGGGGGGCTTTTGCCattttttcatctctctctctctctcttttcaaaAAAGCCATGACGGCTATCCCACAATTCATCTTCCCCGCGCCATCTttgtattatttctaatttattttggATGTCAAAGGCATTGATGAAGATATTTTCTCTGGAGTCTCCCTTCTAACCCGGCTCTCCCGATGTGAACCGAGCTGAAAGCCACCACCAACCACCATGTCTCGCCGCAAGCAAGGCAAACCCCAGCACTTAAGCAAACGGGATTTCTCGCCCGAGCCCCTGTCATCTGTGGTCTCAGAGGAGAGGCAGGAACAGCACGGGCTGGTACAGGTCGCTCCGGAAGGGGACCAGGACCTGCTTACTTGCGGCCAGTGTCAGATGAACTTCCCTTTGGGGGATATCCTGATTTTTATTGAGCACAAAAGGAAGCAATGCAATGGCACCCCGTGCATGGACAAGGCAATGGATAAACCCCCTTCTCCGTCGTATAGCGAGCTGAGGAGAGCCTCCAACCCTGTAGAAGTGGGCGTCCAGGTCACGCCGGAGGACGACGACTGCTTGTCAACGTCTTCTCGAGGAATCTGTCCTAAACAGGAGAACGTTACAGGTAAAGATGAGCCCAGCAGCTACACCTGCACAACCTGCAAGCAGCCGTTCAGCAGTGCCTGGTTCCTGCTGCAGCATGCCCAGAACACTCACGGCTTCCGCATCTACCTGGAGAGCGAGCGCGGGAGCCCTCTCACGCCTCGCGTGGGTGCCCCATCCGGGATGAGCGCTGAACATGCCTCCCAGCCACCCTTACATGGCATCCACCTACCCGAGGGCAGCCCCTTCAACTTGTTACGGATACCTAACTCTGCCCGTGAGGGCCCCCCTCTCCGGGAGGGGCGGTTTCCCCCGACTCCCCCGCTGTTTAGCCCTCCACCCCGCCATCACCTGGACCCGCACCGCATGGAGCACCTGAGCCCGGAGGAGTTGGCCCTGGCCACCCACCACCCGAGTGCCTTCGACAGGGTGCTGCGCCTCAACCCCATGCCCCTGGACCCCCCAGCCATGGACTTTTCTCGCAGGTTGAGGGAGCTGGCCGGCAACACCTCAGGGTCAACTCCGCCCCTCTCGCCCAACCGGCCCAGCCCTATGCAACGGCTGCTGCAACCATTCCAATCCAACGCCAAGCCGCCCTTTCTGTCCACCCCTCCGCTTCCCTCTGTGCAGTCCCCATCCGGCTCCCAATCCACTCCCACTCCACTGCCCCAGCAGCCCAACACCCCCATGAAGTCCAAGGCCTGCGAATTCTGTGGGAAGACGTTCAAGTTCCAGAGTAACCTGATTGTGCACCGGCGCAGCCACACAGGCGAGAAACCCTACAAGTGCCACCTGTGTGACCATGCCTGCACCCAGGCAAGCAAGCTGAAGCGGCACATGAAAACGCACATGCACAAATCCTCGCCCATGACGGTCAAGTCAGACGACGGACTCTCCACGGCAAGCTCCCCTGAACCAGGGACCAGTGACCTGGTGGGCAGTGCTAGCAATGCCCTCAAGTCTGTAGTGGCCAAGTTCAAAAGTGAGAATGACCGCATGATTCCAGAGAAtggggaggaggaagaggaagaggaagaagaggaggaggaggaagaggaagaagaagaggaagaggaggaaggtgAAGACGAAGAGGAGCTGGAACGAGAGAGAGGGCGCAACAGCTTTCACTTTGGCCTAAACCTGGAGGCTGCGCGGCACCACGAAAACAGCAGTGGGCGCTTAGGCGTGAACGAGGACAGTATCCCGCGATCTCTGCCTGAGGTGATGCAGGGCATGGGTTTGGCAGCCAGCATGCAGCATTACAGCGAGGCCTTCCACCAACACAAACGGGGCGCACTCAACTCAGATAGTGACGCACACAGGGACATGTGCGACGAGGACTCTGCCTTGGAGTCGGACCGCGCACAAGAAGGCTGCGGCTCGGCCATCAATGGCCGGGGCTCGTCCCCCAGCGAGTCGGCTTCTGTGGGTCTATCCAAGAAGCTGTTGCTGGGCAGTCCCAGCTCCCTCAGCCCCCTTTCCAAACGCATCAAGATGGAGAAGGACTTTGACCTCCCCACACCCACCATCCCCAACACTGAGAACGTATACTCCCAGTGGCTGGCTGGCTACGCTGCCTCTCGCCAGCTCAAGGACCCCTTTCTGAATTTCGGGGATTCCAGACAATCGCCTTTCGCCTCATCTTCAGAGCACTCCTCAGAGAACGGCAGCTTGCGCTTCTCCACGCCCCCGGGGGAGCTGGACGGTGGCGTGTCCGGACGTAGCGGGACGGGCAGTGGAGGGAGTACGCCGCACCTCGGCGGTCACGGCCGGCCCAGTTCGAAAGACGGGCGGCGCAGCGACACTTGCGAGTATTGTGGGAAAGTGTTCAAAAACTGCAGCAACCTGACGGTGCACCGGCGTAGTCACACAGGCGAGCGGCCCTACAAGTGCGAACTCTGCAACTACGCCTGCGCCCAAAGCAGCAAGCTCACGCGGCACATGAAAACGCACGGGCAGGTGGGCAAGGACGTTTACAAATGTGAAATCTGTCAGATGCCTTTTAGTGTGTATAGCACCCTGGAGAAACACATGAAAAAATGGCACAGTGATCGCGCCTTGAACAGCGAAATTAAAACTGAATAGTGCTGGAGAATGGAGGCACACCTGCCAGTAAACAGCAACCCTCCCACCCAAACCCCACCCTTGTAGATTTTCCCTGTTTGGCTAGTCCAGTGGAGGCTAAGACAACGTGCTTGGCACCACCAGCACACCCTTCTTCATTTACCGTTGAATGCATGTTCTGTATCGGGGCAATACTATTGCATTGACGCAAACTTCGAGCCTTTCTCTTGTGCAATAATTTAcatgttgtgtattttttttctttttttctttccctttttttgatAATTAGACAGCATGCATGGTATGTTTtggctattttaaaaaaattgtccCTGGTTGGTTAGTTGTTGAGTAAATGTGTTGCTGTtttcttgttctgttttttaattcaaaaaatgaaaagagaaaagaaaagaaaaaaacaaccatgCTGCATACATTCTGTAATACATATCATGTACAGTTTTGTGTTGTAACATGGAGGACAACAGTCTATTGCTTAAACCCTCTTTGGAGGGGCTGGGAATCGCACTTAAACTAATCTTTCAAAAAGATGTTCTGTCCACATAGGGTTAAACATAGTAATTGGCCCCTATTATGGAATATAAAGTATTGACAGCCTttgaatttctttaaaaaaaaaaaacacacacatataggtGATCGAGATTTGAATTTGTACTATCATttggtaaaacaaacaaaaaaaagagtgcCTTGGATCTTGAAACTTCATTGGTTAATCTTCCTATCTGCTATAAGCTTGGAATCTCAGCCAGATACTGGAAATGGATTTATTTGATTCACGTAAGGTTCTTGCATCAAGTACCTGACTTTGACAGTCTACAAGGAAAAAATGATGATAATCAAAAAGCTAAAAGCTGATTTGTAGTTAATCATCATTAGCTACCTATGACACATGCATCCTTCTATTGTGGTATTTGTACTGTGCACGGTACATCCAGTATTGTGTGGGATTCAACCATGTTTACTCTCCAGTTATGGGTACTGTACTTACTCGGTACAGGTTTTTTCAAACCACAATCATAAGCTCTCGTGAAGATTCTGTTCTCAGTAGCACAGCAGTCTTTTGTTTtccatagtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgtgcaggcgcgagtgtgtgagtatgtgtgtgtccaCTGCATAGGTACATTTGCGGGCCTATACGATAaagaaatgcagtgttttttgaaAATTCCTCTTCGAAGAATGCATCTGATTATTTACACGTCTCAGTGATGATTAACTATGAATTGCCTACAGGTCTGAATCGAAATCCTCAAAAGAATATCTCTAGCAATGACTGCAGTACTTAATACCTGTGTTCCCTAAATGGTTCCATCAACCtgggagacaaagagagagagagagagagagagagaggggagaggagaGGGAAAGACTTTTCGTGTGTAATTATGTGTTTGGGgagttgtttttttcctctggtGAGTTAAACATCCATCCATTTTTGACAACCATGTTTTCAGTGTTTAGTTAGCACTTGTCACTCGGCCCCTTCAGTCTGTGTCTGACGCTCTGATTGGTGGTATAGCGGTTGAGTATAAATTGAGACTGCTTGCTTATACAACATTAAGTGCACTGTTAAAAGTTTCCCAGTTTACAGGTATTCACATGAGGGAAAACTTCCTATAatgctaaaaaaagaaaaagaaaataatttaaaaaaataatacagtgtCATTGTTTAACATAACACAGCCAACTCCTCCCTCCTcccaccaccccccaccccaccctctTACAGAAAGCCCAACTCCAGTATGATGTTCAAGCGTCGGGGCATAGACCTCCTGTCAAACAATGGACGATTGAAACTTGCTGCTTTCACTGcaagaacatttttttgtacaaaaaaaaaaaacgtttttaagtatgaatataaaatgacatttttaaaaaaaatagcaattcaTTATCTTAGGGGAAACTGTATTTAAGTTTGTTGATGTTTCTCTTTCCTCTTTGTCTTGGTGGTGTTCAAGACTTGATCACGATATATAtagaattggaaaaaaaatctgtgatttttttttttcccttttttttttttcctttttatttcttctttttttccaccGTGGCTCTTCACAGCTCTTCAGGTCAAACGTAACTTGCATTGGGGAAAGGTTTaagattatatataaatatataatagagaACTTAAATATAGGAAAATGCACACTCATGTTCAATTCCTatgctaaaacacatttatgatctactttttttctgtatttctagaATGGTATTTGAATTAAATGTTCACCTAGTGTAGGCACTATAGTATTTATATTGAGGCTTGTATTTTTAACTGTTGCTTGTTCTCTCAAAAGGTATTATTGTACCTTTTTTGGtagtggaaaaaaacaacaagctgCCAcggtatatttttttaatttggcaggATAATATAGTACGaattatttgtatgtttaaaaaaaaatgaactgaaaaaaaatttcaataaaaaaacaactaaagtaTGTGGCATTGTATAAAAAGGAGGCCATCTAATGGTTTCCCCGAGGAGTCTTTTGCGAATGTCCACACTAGCTAAAACAGGTGGTTGTAcatatctttttttctgttctttttttagacTCTCCTCTTCTGCTGCCATTCTGTATGCAGTAATGCAAGCTGATGTTGGGTTCTTCTGTAGTGTGCTTCTCTGTCTTCTCACCTATCTCACCTGACTACATTCCAGCATCTTAAAGAGAACAAACTTCATATGCAGTAAATACCAGTACATAAATGAAAATCattcaaataaatgaattaaaaataatcaaagttttgcaggttttttgttttcattgccAAATACTAAATGGTGCTTTATATTTAGATTGGGATGACTTTCATATGcaaagcatatttaaaaatgaaatggaaATAATGGAAAGCCCGCTTGAGTTCATACTTTTTTGTAAATGGCAATGCGGAATATTTTGTTATCAGCCTTTTCTATTCCTGTTCTGAAAGCTGTTTGTTgtaacttgaacttgaactttaTCTTTTACAATGGGAGtcactatttattattacttaaatGCTCTGTTCAGAACGGAGACATGGAATGGAtcttttttggttttctttattttgtttttgttattgttgtttttctttgaaAATGACCAAAGGTCATTGACAACCTTTGCTTTTATTTGCTGTATTTGTTTCTGGTCTATGTTGAGTTTTATTGGAGAAACCACTGTCTGTGTTTTCTGGCAGTTGTCTGCATTATCCTGTTCACACACCCATTTTGTCCCTTTAttgaaaacaattaataaaaaaattaaagta

Function


symbol description
bcl11aa Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within brain development. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Orthologous to human BCL11A (BAF chromatin remodeling complex subunit BCL11A).
bcl11a Enables several functions, including DNA-binding transcription repressor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in negative regulation of transcription by RNA polymerase II and regulation of neuron projection development. Located in nucleoplasm. Implicated in autism spectrum disorder; beta thalassemia; schizophrenia; and sickle cell anemia. Biomarker of lung non-small cell carcinoma.

NR:

description
PREDICTED: B-cell lymphoma/leukemia 11A

GO:

id name namespace
GO:0046872 metal ion binding molecular_function
GO:0003676 nucleic acid binding molecular_function

KEGG:

id description
K22045 BCL11A; B-cell lymphoma/leukemia 11A

RNA


RNA id representative length rna type GC content exon number start site end site
TU293854 False 1776 lncRNA 0.36 2 14768261 14780313
XM_007252237.3 True 6123 mRNA 0.46 3 14722400 14780274

Neighbor


gene id symbol gene type direction distance location
LOC111195974 NA coding upstream 81857 14639866 ~ 14640543 (+)
pcbd1 pcbd1,LOC107743500,LOC107601888,LOC107655445,LOC107559335 coding upstream 109832 14608175 ~ 14612568 (+)
sec23ip sec23ip,LOC107655440,LOC107666414,LOC107743502,LOC107601884 coding upstream 216554 14493853 ~ 14505846 (+)
inpp5f inpp5f,LOC107666413,LOC107726944 coding upstream 243340 14454016 ~ 14479060 (+)
bag3 bag3 coding upstream 271529 14442676 ~ 14450871 (+)
fancl fancl,LOC107585345 coding downstream 736425 15516738 ~ 15542681 (+)
LOC103023506 LOC103023506 coding downstream 1069539 15849852 ~ 15854753 (+)
slc24a3 slc24a3,LOC107693448,LOC107718828,LOC107716313,LOC107673935 coding downstream 1114292 15894605 ~ 16015675 (+)
LOC103022884 NA coding downstream 1237087 16017400 ~ 16022839 (+)
rin2 LOC108442550,LOC107673857 coding downstream 1244507 16024820 ~ 16086964 (+)
G216532 papolg non-coding upstream 20662 14696928 ~ 14701738 (+)
G216530 papolg non-coding upstream 26626 14695339 ~ 14695774 (+)
G216523 NA non-coding upstream 67119 14655036 ~ 14655281 (+)
G216520 NA non-coding upstream 77318 14642918 ~ 14645082 (+)
G216507 NA non-coding upstream 91605 14623660 ~ 14630795 (+)
LOC111195976 NA non-coding downstream 111888 14892201 ~ 14911987 (+)
LOC111195977 NA non-coding downstream 131686 14911999 ~ 14923278 (+)
G216793 NA non-coding downstream 889205 15669518 ~ 15669736 (+)
G216831 NA non-coding downstream 1134618 15914931 ~ 15923311 (+)
G216893 NA non-coding downstream 1328416 16108729 ~ 16109441 (+)
gsto1 gsto1 other upstream 375067 14342232 ~ 14347333 (+)
spef1 spef1 other upstream 972094 13740513 ~ 13750306 (+)
LOC103033819 LOC108426824,LOC108263419,LOC107725444 other upstream 1238029 13479176 ~ 13484371 (+)
trnay-gua_11 NA other upstream 1406238 13316075 ~ 13316162 (+)
trnay-gua_10 NA other upstream 1407200 13315112 ~ 13315200 (+)
borcs7 borcs7 other downstream 2224228 17004541 ~ 17007537 (+)
LOC111195981 tacc2 other downstream 2369029 17149342 ~ 17184251 (+)
pax2 pax2,pax2a,LOC107668824,LOC101463634,LOC107588637,LOC107716343,LOC107585307 other downstream 3223940 18004253 ~ 18039352 (+)
eif4ebp2 eif4ebp2,LOC107564345,LOC107716353,LOC107668794,LOC107673927 other downstream 3531580 18311893 ~ 18317228 (+)
LOC103030769 LOC103030769 other downstream 3962893 18743206 ~ 18744327 (+)

Expression



Co-expression Network