Item | Value |
---|---|
gene id | lef1 |
gene name | lef1 |
gene type | coding |
species | mexican tetra (Astyanax mexicanus) |
category of species | ornamental fish |
Item | Value |
---|---|
chromosome id | NC_035921.1 |
NCBI id | CM008324.1 |
chromosome length | 46505145 |
location | 6648941 ~ 6728983 (+) |
genome version | Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome |
symbol | description |
---|---|
lef1 | Enables sequence-specific DNA binding activity. Involved in regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; fin development; and fin regeneration. Predicted to be located in nucleus. Predicted to be part of beta-catenin-TCF complex. Is expressed in several structures, including midbrain hindbrain boundary neural rod; nervous system; neural crest; pleuroperitoneal region; and trunk. Used to study anxiety disorder. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human LEF1 (lymphoid enhancer binding factor 1). |
description |
---|
lymphoid enhancer-binding factor 1 isoform X3 |
id | name | namespace |
---|---|---|
GO:0060070 | canonical Wnt signaling pathway | biological_process |
GO:0022407 | regulation of cell-cell adhesion | biological_process |
GO:0048747 | muscle fiber development | biological_process |
GO:0021542 | dentate gyrus development | biological_process |
GO:0010628 | positive regulation of gene expression | biological_process |
GO:0042100 | B cell proliferation | biological_process |
GO:0061153 | trachea gland development | biological_process |
GO:0001755 | neural crest cell migration | biological_process |
GO:0001756 | somitogenesis | biological_process |
GO:0071864 | positive regulation of cell proliferation in bone marrow | biological_process |
GO:0071866 | negative regulation of apoptotic process in bone marrow cell | biological_process |
GO:0002040 | sprouting angiogenesis | biological_process |
GO:0021861 | forebrain radial glial cell differentiation | biological_process |
GO:0021873 | forebrain neuroblast division | biological_process |
GO:0071895 | odontoblast differentiation | biological_process |
GO:0021879 | forebrain neuron differentiation | biological_process |
GO:0030509 | BMP signaling pathway | biological_process |
GO:0046632 | alpha-beta T cell differentiation | biological_process |
GO:0030223 | neutrophil differentiation | biological_process |
GO:0001837 | epithelial to mesenchymal transition | biological_process |
GO:0016202 | regulation of striated muscle tissue development | biological_process |
GO:0032696 | negative regulation of interleukin-13 production | biological_process |
GO:1900052 | regulation of retinoic acid biosynthetic process | biological_process |
GO:0032713 | negative regulation of interleukin-4 production | biological_process |
GO:0032714 | negative regulation of interleukin-5 production | biological_process |
GO:0001569 | branching involved in blood vessel morphogenesis | biological_process |
GO:0031101 | fin regeneration | biological_process |
GO:0021943 | formation of radial glial scaffolds | biological_process |
GO:0043154 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | biological_process |
GO:0050769 | positive regulation of neurogenesis | biological_process |
GO:0048341 | paraxial mesoderm formation | biological_process |
GO:0048922 | posterior lateral line neuromast deposition | biological_process |
GO:0060784 | regulation of cell proliferation involved in tissue homeostasis | biological_process |
GO:0021979 | hypothalamus cell differentiation | biological_process |
GO:0030879 | mammary gland development | biological_process |
GO:0001649 | osteoblast differentiation | biological_process |
GO:0048069 | eye pigmentation | biological_process |
GO:0033334 | fin morphogenesis | biological_process |
GO:0030326 | embryonic limb morphogenesis | biological_process |
GO:0033336 | caudal fin development | biological_process |
GO:0033339 | pectoral fin development | biological_process |
GO:0060561 | apoptotic process involved in morphogenesis | biological_process |
GO:0060325 | face morphogenesis | biological_process |
GO:0005667 | transcription regulator complex | cellular_component |
GO:0005737 | cytoplasm | cellular_component |
GO:0043565 | sequence-specific DNA binding | molecular_function |
GO:0070016 | armadillo repeat domain binding | molecular_function |
GO:0003682 | chromatin binding | molecular_function |
GO:0008013 | beta-catenin binding | molecular_function |
GO:0008301 | DNA binding, bending | molecular_function |
GO:0045295 | gamma-catenin binding | molecular_function |
GO:0030331 | estrogen receptor binding | molecular_function |
id | description |
---|---|
K04492 | LEF1; lymphoid enhancer-binding factor 1 |
RNA id | representative | length | rna type | GC content | exon number | start site | end site |
---|---|---|---|---|---|---|---|
XM_007229470.3 | False | 2004 | mRNA | 0.51 | 10 | 6648941 | 6728929 |
XM_007229473.3 | True | 2098 | mRNA | 0.51 | 11 | 6648942 | 6728983 |
XM_007229474.3 | False | 1931 | mRNA | 0.50 | 11 | 6648942 | 6728822 |
XM_015604655.2 | False | 1928 | mRNA | 0.50 | 11 | 6648942 | 6728822 |
XM_022684507.1 | False | 1998 | mRNA | 0.51 | 10 | 6648941 | 6728929 |
XM_022684508.1 | False | 1995 | mRNA | 0.51 | 10 | 6648941 | 6728929 |
gene id | symbol | gene type | direction | distance | location |
---|---|---|---|---|---|
trnam-cau_43 | NA | coding | upstream | 167312 | 6481558 ~ 6481629 (+) |
LOC103036066 | NA | coding | upstream | 190620 | 6454447 ~ 6458321 (+) |
LOC103035747 | NA | coding | upstream | 200775 | 6435721 ~ 6448166 (+) |
LOC103042697 | NA | coding | upstream | 215813 | 6428242 ~ 6433128 (+) |
LOC103036371 | NA | coding | upstream | 233323 | 6411469 ~ 6415618 (+) |
gstcd | gstcd,LOC107757010,LOC107729368 | coding | downstream | 56607 | 6785590 ~ 6993387 (+) |
npnt | npnt,LOC107729354,LOC107675850 | coding | downstream | 283536 | 7012519 ~ 7142268 (+) |
aimp1 | aimp1,LOC107594432,LOC107757008,LOC107729369 | coding | downstream | 544222 | 7273205 ~ 7301823 (+) |
pkd2 | pkd2,LOC107684281,LOC107583176,LOC107706826 | coding | downstream | 737194 | 7466177 ~ 7481674 (+) |
LOC103045679 | NA | coding | downstream | 800597 | 7529580 ~ 7549205 (+) |
G214290 | NA | non-coding | upstream | 16567 | 6632065 ~ 6632374 (+) |
G214283 | NA | non-coding | upstream | 67208 | 6581294 ~ 6581733 (+) |
G214215 | NA | non-coding | upstream | 175197 | 6380944 ~ 6473744 (+) |
G214227 | NA | non-coding | upstream | 178741 | 6469473 ~ 6470200 (+) |
G214174 | NA | non-coding | upstream | 373018 | 6275714 ~ 6275923 (+) |
G214304 | NA | non-coding | downstream | 27422 | 6756405 ~ 6756758 (+) |
G214313 | NA | non-coding | downstream | 27989 | 6756972 ~ 6759193 (+) |
G214340 | NA | non-coding | downstream | 139734 | 6868717 ~ 6869146 (+) |
LOC111195949 | NA | non-coding | downstream | 204972 | 6933955 ~ 6939059 (+) |
G214362 | NA | non-coding | downstream | 280889 | 7009872 ~ 7010111 (+) |
LOC111196031 | NA | other | upstream | 239873 | 6399076 ~ 6409068 (+) |
G214175 | NA | other | upstream | 364573 | 6283781 ~ 6284368 (+) |
G214006 | NA | other | upstream | 1127266 | 5521184 ~ 5521675 (+) |
LOC103034491 | scoc,LOC103034491,LOC108434805,LOC107674238,LOC108263532,LOC103132857,LOC103463814,LOC106946201 | other | upstream | 1289209 | 5349167 ~ 5359732 (+) |
G213891 | NA | other | upstream | 1474845 | 5173069 ~ 5174096 (+) |
pold4 | NA | other | downstream | 1081995 | 7810978 ~ 7813036 (+) |
LOC103021346 | LOC108412479 | other | downstream | 1127179 | 7856162 ~ 7877118 (+) |
G214773 | NA | other | downstream | 1381965 | 8110948 ~ 8111325 (+) |
LOC103041196 | LOC108443732,LOC107582026,LOC107601840 | other | downstream | 2229316 | 8958299 ~ 9030598 (+) |
sprn | sprn | other | downstream | 3846512 | 10575495 ~ 10583088 (+) |