hk1 (hk1,LOC107676584)


Basic Information

Item Value
gene id hk1
gene name hk1,LOC107676584
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035921.1
NCBI id CM008324.1
chromosome length 46505145
location 9524819 ~ 9542971 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007240834.3
CTCAATCAAGTGCCATTGAGCCCCTGCTGTTGTTTGCATTCTTATTAACCTTTTGACCCTGGTCCCCAGCTCTTTTAAATGATCTCATTTACTATGGATTCTCTTTGTCATCACTTTCTTTTCCCTAATACATGTTTCGCTATAGTGGTGGAGCAGGATGATAGCCGCACAGCTTCTGGCCTACTACTTCACTGAGCTGAAGGATGACCAGGTCAAAAAGATCGATAAGTACCTGTATTCCATGCGGTTCTCTGATGAGACGCTGCGGGACATCAAGGCCCGTTTCCGTATGGAGCTGGAAAAAGGGCTGAGCCGGGACACCAACCCCACAGCCACCATCAAGATGCTGCCCACCTTTGTCAGATCCATCCCTGATGGATCAGAGAAGGGGGATTTTATTGCTCTGGATCTGGGTGGCTCTAATTTCCGAATCCTGCGTGTGAAAGTCTCTCATGAGAAGAAACAGACGGTGCAGATGGAGAGTCAAAATTACGAAACCCCTGAGGACATCATCCATGGCAGTGGATCACGGTTGTTTGACCATGTTGCAGAATGTCTAGGAGACTTTATGGAGAAGCAAAAGATCAAAGACAAAAAACTGCCTGTTGGATTCACTTTTTCTTTCCCATGTGTTCAAACTAAACTGGATGAGgcTGTTTTGCTGACTTGGACCAAACGATTTAAAGTCAATGGAGTGGAAGGAATGGATGTGGTCAAGCTTCTGAACAAAGCTATCAAAAAGCGAGGGGATTATGATGCAGATATCATGGCGGTGGTCAATGATACTGTGGGAACTATGATGACCTGTGGCTTTGATGATCAGCGCTGTGAAGTAGGAATCATCATTGGTACAGGCACTAATGCATGCTACATGGAGGAACTGAGACACATTGACCTGGTGGAAGGAGACGAGGGCAGGATGTGTATCAATACAGAGTGGGGAGCTTTTGGAGACGATGGCATGTTAGAGGACATCCGCACTGAGTTCGACAGAGAGATTGACCGTGGATCTCTTAACCCTGGCAAACAGCTGTTTGAAAAGATGGTGAGTGGTATGTACATGGGGGAGCTGGTCAGGCTCATCCTGGTGAAGATGGCCAAAGAGGGACTGCTGTTCGAGGGCCGCATCACTCCTGAGCTGCTGACGAAAGGCAAATTTGAAACAAAGCATATTTCAGCCATTGAGAAgACTAAAGAGGGTCTGACCAAAGCCAAGGAAATTCTGACCCGCCTGGGCGTGGAGCCATCAGCGGATGACTGCATCGCAGTGCAGCACGTGTGTGCCATTGTCTCTTTCCGCTCTGCCAACCTCATCGCTGCTACCCTGGGTGCTATCCTCAATCGGCTGAAGGACAACAAAAACGTACCTCGCCTCCGTACCACCGTGGGCATTGATGGATCCCTTTACAAGATGCATCCACAGTATTCTCGACGGCTGCACAAGACCGTCCGCCGTCTGGTACCAGAATGTGATGTGCGCTTCCTGCTCTCAGAGAGTGGGAGTGGCAAAGGTGCTGCCTTGGTGACAGCCTGGGCTTCTCGATTGGCTGATCAGACCCGTCAAATCGCAGAGATCCTGGCTGAGTTCCGCCTCACCCAGGACCAGCTGCTGGAGGTGAAGAAGAGAATGCTCACAGAGATCCAGACTGGCTTGAGCAAGAAGACTCAGGACAAGGCTACTGTCAAAATGCTGCCCACCTATGTCCGCAGCACTCCAGATGGAACAGAAAATGGTGACTTCCTGGCCTTGGATCTTGGAGGCACAAACTTTAGAGTGCTCTTAGTGAAGATTCGCAGTGGTAAAAGAAGGACTGTGGAGATGCATAACAAAATCTATGCCATTCCCATAGAGGTGATGCAGGGAACAGGAGAAGAGCTCTTTGATCACATTGTTGCCTGCATATCGGACTTCCTGGATTACATGGGCATGAAGAACGCCCGACTGCCTTTGGGCTTCACCTTCTCCTTCCCTTGCAGACAGACCAGCCTAGACGCTGGCATTCTTGTAAACTGGACAAAGGGCTTCAAGGCCACAGACTGTGAAGGAGAGGATGTGGTAAATCTCTTGAGGGAGGGGATTAAAAGGAGAGAGGAGTTTGACCTAGATGTAGTAGCAGTGGTTAATGACACAGTGGGAACCATGATGACTTGTGCATATGAGGAGCCAACATGTGAAGTCGGCCTTATTGCAGGAACGGGCAGCAATGCATGCTACATGGAGGAGATGAAGAACATTGAGACAGTGGATGGAGACCAGGGCAGAATGTGTGTGAACATGGAATGGGGTGCTTTTGGAGACAATGGCTGTTTGGATGATATCAGGACCCAGTATGACAGAGCTGTGGATGACCTCTCCCTCAACCCTGGCAAACAGAGGTATGAGAAGATGTGCAGTGGAATGTACCTGGGTGAGATTGTGCGGAACATCCTTATTGATTTAACAAAGCGTGGCTTCCTCTTCAGAGGGCAGATTTCTGAAACTCTGAAAACAAGGGGCATCTTCGAAACTAAATTCCTGTCCCAGATTGAGAGTGACCGTCTGGCTCTACTGCAAGTGAGGTCCATTCTGCAGCACTTGGGTCTGGACAGCACGTGTGATGACAGTATTATAGTAAAGGAGGTGTGTGGGGCAGTGTCACGCCGAGCTGCGCAGATCTGTGGAGCAGGAATGGCTGCTGTTGTGGACAAAATCCGGGAGAATAGGGGACTGGACCATCTGGACATCACTGTTGGCGTGGACGGCACGCTCTACAAACTCCATCCACAtttctcCCGGATAATGCACCAGACCGTCAAGGAACTCGCTCCAAAGTGCGATGTGAACTTCCTGCTGTCTGAAGATGGAAGCGGGAAGGGTGCTGCCTTGATCACGGCCGTGGGATGCCGCCTGCGTGAGCAAGAGCAAAAAAGCTGAAGCCTCCTGGGACCAGCCATTTAGCGCCCTTTCACTCTAACCAAGAGCAGAGAACTTTCCCACTTGCAGCCGTGACAGAAGTTCTCCACCTAATGTCCAGCACCTTTACCTGCCCATGCTTCAGTTCCAGAGCGTGGGATCCTCCAAACTTCGTATTTCACTCCATTTGAACTAATGTAACTGTCAGCCTTTCACCGTGTCTGAATTTAGTGTCCATGTCtaagtgtatttgtgtgtatgtatcaCAGATGGGCTATCCCTTATTACTAAGTCTATACTGAGATGTTGTAACTGCTGTAAACATTTTATGGATGTATATTATTAGCAAAAGGGAAGAAATTTCAAGGCAAAGCGACAAGACcaactatatatacatataagagtatattatttattttatttttgtatttgaaggGTATATTGAGAGAAGAGTGTAAGAGGAATGATGCGTGATAActtaagagagaaagaaggttaaaagtttctttttttagtctGTGTTTATGCCATATgctcattttcaaactgttgcatcttggcatttctCTGATAACAGAAAGGTTTATTATATGAATGTTGGGAGACAAGCTGGCTTCTGTGACCACGCCCACTTCCCTCTGAGGCTGAGGAAGAGGATACAGTACAATTCCATTCTCTAGTCAAGGCTGCCTCCCAGGGAACTGTTTCCACACACCCTGTAACCTCAGCTCCTGAAGACCCAACAAACAAAAGATTCAACAGGAAAAGAGACTTGCCTTTGTTATCCAGATCCTCTGAAACACAGCCTGCTCCTGCGGTGCCCGGAAACCCGAGCGGTTGCAGCGGACTAGACCATAACATTTTGCTTTCGTGAAAGTAGGTGAGAATTGTCAGCATTTGCTGTGTGCTGTGTATAAATGCAGATAGGCCATTGATTCCCCCAACCCCACCCCCACAAATAATGGTGCAAATATCTAGTAAATGTCCTTGTGTGTACTCTggctgagtgtttgtgtgtgatccTGTATAGTTACTATGAGTGAATCTGTGCAGTGGCTCTGAGATGGTATGATGAATGCATGCCTTATTTGGAAAAACAGAGGTTTAGTATCCACTCATTTTGTACAATTATATAGGTGCACCATATTTAGATGTTCTTTAAACGAAAAATGATTAAACTATTTTGAAGAGCTATG

Function

symbol description
hk1 Predicted to enable fructokinase activity; glucokinase activity; and mannokinase activity. Predicted to be involved in cellular glucose homeostasis; glucose 6-phosphate metabolic process; and glycolytic process. Predicted to act upstream of or within carbohydrate metabolic process and phosphorylation. Predicted to be active in cytosol and mitochondrion. Is expressed in several structures, including cardiovascular system; mesoderm; musculature system; nervous system; and neural tube. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4G; anemia (multiple); hematologic cancer (multiple); obesity; and retinitis pigmentosa. Orthologous to human HK1 (hexokinase 1).

NR:

description
hexokinase-1

GO:

id name namespace
GO:0046835 carbohydrate phosphorylation biological_process
GO:0051156 glucose 6-phosphate metabolic process biological_process
GO:0006096 glycolytic process biological_process
GO:0001678 cellular glucose homeostasis biological_process
GO:0005829 cytosol cellular_component
GO:0005524 ATP binding molecular_function
GO:0008865 fructokinase activity molecular_function
GO:0004340 glucokinase activity molecular_function
GO:0019158 mannokinase activity molecular_function

KEGG:

id description
K00844 HK; hexokinase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007240834.3 True 4089 mRNA 0.47 19 9524819 9542971

Neighbor

gene id symbol gene type direction distance location
LOC103047009 hkdc1,LOC103047009,LOC106612435,LOC107676583 coding upstream 8880 9496834 ~ 9515939 (+)
supv3l1 supv3l1,LOC107725491,LOC106612443,LOC107601833,LOC107666535 coding upstream 30290 9483598 ~ 9494529 (+)
vps26a vps26a,LOC107666532 coding upstream 44274 9469084 ~ 9480545 (+)
srgn srgn coding upstream 58713 9461330 ~ 9466106 (+)
kif1bp kif1bp,LOC107743600 coding upstream 83905 9432604 ~ 9440914 (+)
tspan15 NA coding downstream 22977 9565948 ~ 9614642 (+)
cfap43 NA coding downstream 89420 9632391 ~ 9653852 (+)
rufy2 rufy2,LOC107676589,LOC107743555,LOC107725492,LOC107563060 coding downstream 117529 9660500 ~ 9679057 (+)
LOC103028294 LOC108438200 coding downstream 153056 9696027 ~ 9759882 (+)
glud1 glud1,glud1a,gdh01,LOC103026661,LOC108438199,LOC107743560,LOC107563055,LOC107725450 coding downstream 257725 9800696 ~ 9817693 (+)
G215103 NA non-coding upstream 42238 9481672 ~ 9482581 (+)
G215102 NA non-coding upstream 43281 9481315 ~ 9481538 (+)
G215094 NA non-coding upstream 56420 9466620 ~ 9468399 (+)
G215039 NA non-coding upstream 214646 9288076 ~ 9310173 (+)
G215011 NA non-coding upstream 454952 9068995 ~ 9069867 (+)
G215197 NA non-coding downstream 151946 9694917 ~ 9695273 (+)
G215199 NA non-coding downstream 217317 9760288 ~ 9762248 (+)
G215215 fam35a non-coding downstream 244181 9787152 ~ 9788616 (+)
G215224 LOC107601818 non-coding downstream 276293 9819264 ~ 9890322 (+)
G215236 bmpr1aa,LOC108438195,LOC107666410,LOC107696892 non-coding downstream 347851 9890822 ~ 9891888 (+)
LOC103041196 LOC108443732,LOC107582026,LOC107601840 other upstream 494221 8958299 ~ 9030598 (+)
G214773 NA other upstream 1413494 8110948 ~ 8111325 (+)
LOC103021346 LOC108412479 other upstream 1647701 7856162 ~ 7877118 (+)
pold4 NA other upstream 1711783 7810978 ~ 7813036 (+)
LOC111196031 NA other upstream 3115751 6399076 ~ 6409068 (+)
sprn sprn other downstream 1032524 10575495 ~ 10583088 (+)
G215513 polr1b other downstream 1404108 10947079 ~ 10948287 (+)
cpeb3 cpeb3,LOC106604870 other downstream 1582729 11125700 ~ 11195423 (+)
LOC111195936 NA other downstream 2067347 11610318 ~ 11613123 (+)
G215834 NA other downstream 2662530 12205501 ~ 12206164 (+)

Expression


Co-expression Network