polr1c (polr1c)


Basic Information

Item Value
gene id polr1c
gene name polr1c
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035921.1
NCBI id CM008324.1
chromosome length 46505145
location 17063896 ~ 17067641 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007249462.3
AAACCAGCTTTGGTTGGACCAGAAGTAGAGAAGAGGCAAGCGGAGCAGGAATGATGGCGGCGCCTATGAGAAACGTGGATGAGATCCGTGACAGAGTGATTTTGGGTGAATTTGGTGTTAGAAATGTCCATTCCACAGATTTCCCGGGAAATTACCCTGGTTATGATGACACATGGGACCTGAGGAAATTCAAAAAGAACTTCAGGCTTAACATTGCTCATATGGATGAAAACACTCTGGAGTTTGATATGGTGGGAATAGATGCTGCCATTGCCAATGCTTTTCGTCGGATTCTACTTGCTGAGGTTCCAACTATGGCAATTGAGAAGGTTTTCATTTACAACAATACATCGATCATTCAGGATGAGATTTTAGCCCATAGGCTTGGTTTGGTACCCATCAAAGCTGATCCTCGTCTTTTTGAGTACAGAAATGCTGgtgATGAAGAAGGCACAGAAATTGATACAATTCAGCTTCAGTTAAAGATTAAATGCACAAGGAATACCAGAGCTGCAAAAGACTCGTCAGATCCCAAAGAACTTTACCTCAATCACATGGTGTATTCAAAGGACATAACGTGGGTACCTATTGGAAACCAAGCTGATGTGTTTGGTGATTCTAAGATTGGTCCGGTACATGATGACATCCTTTTGGCACAACTTCGGCCAGGACAAGAGCTTGACATAGTTATGCACTGTGTTAAAGGAATAGGCAAAGATCATGCCAAGTTCTCCCCAGTGGCCACAGCTAGCTACAGGTTGCTTCCTGAGATCACGCTACTGCAGACGGTTGAAGGAGAAAAGGCTGAGAGACTAAAGCGCTGCTTCTCAGCTGGAGTCATAGAAGTGGAGAACATAAATGgaGAACAGGTGGCTAAAGTGGTCAACAGTCGGCTAGACACGTGCAGCAGAGAAGTGCTCAGACATGACGATCTAAAGAATTTGGTAAAAATAGGACGAGTGCGGGATCACTTCATTTtCTCAGTGGAGTCTACTGGAATTCTACCACCTGAAGTTCTGGTCAGTGAGGCCATTAATGTACTTATTGCCAAGTGCCAGAAATTTCTCACTGAGCTAGAGTCTTCTGAAATGGAATAGACAAAGGAAAGAAGATtatatatacagacacacacgtCACAGCTGTATATAATAGTGACTTTATTGGGGGAAGGTCGTGGCCAAAGTGGCACACTTCTGGGAGTTTTGTTGTCCTTAAAATGAAAGATTTATAGATCTGTGATCAAGGTcattcagaaaatgtaattCTCAGTTATTTAGCCAGATATTGTAAGTCCAGGGTTTAACACTTTTCTATATGGATGGCTTTGGTGTTCCTTAGGCTTTAGGCTTACGATATCTAGTAACCTGAGAAATCTTGCTTTCTTTAAATGCCCATAGACTTGACTACAACTGACCcatgtaaaaagtaaataacatCGACTATAATAAATCTCAAGAATATTGTGTGTTCTAAAATGTAACATTAATTGtacatctttttttgtattaaacatGCTGTTGACTATCAGTCATGAACTATGAA

Function

symbol description
polr1c Predicted to enable DNA binding activity and protein dimerization activity. Predicted to contribute to RNA polymerase I activity and RNA polymerase III activity. Acts upstream of or within cartilage development; embryonic viscerocranium morphogenesis; and ribosome biogenesis. Predicted to be located in nucleus. Predicted to be part of RNA polymerase I complex and RNA polymerase III complex. Is expressed in several structures, including head; immature eye; midbrain; midbrain hindbrain boundary; and segmental plate. Used to study Treacher Collins syndrome. Human ortholog(s) of this gene implicated in Treacher Collins syndrome 3 and hypomyelinating leukodystrophy 11. Orthologous to human POLR1C (RNA polymerase I and III subunit C).

NR:

description
DNA-directed RNA polymerases I and III subunit RPAC1

GO:

id name namespace
GO:0006351 transcription, DNA-templated biological_process
GO:0005666 RNA polymerase III complex cellular_component
GO:0005736 RNA polymerase I complex cellular_component
GO:0003677 DNA binding molecular_function
GO:0046983 protein dimerization activity molecular_function
GO:0001054 RNA polymerase I activity molecular_function
GO:0001056 RNA polymerase III activity molecular_function

KEGG:

id description
K03027 RPC40, POLR1C; DNA-directed RNA polymerases I and III subunit RPAC1

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007249462.3 True 1542 mRNA 0.41 9 17063896 17067641

Neighbor

gene id symbol gene type direction distance location
LOC103037825 ina coding upstream 7851 17051980 ~ 17056045 (+)
cnnm2 cnnm2,cnnm2a,LOC107673921,LOC107716327,LOC107585325,LOC107588659 coding upstream 34895 17010555 ~ 17029001 (+)
wbp1l wbp1l coding upstream 69488 16982053 ~ 16994408 (+)
fbxw4 fbxw4,LOC107716323,LOC107707737,LOC107694796,LOC107673945,LOC107588663 coding upstream 96490 16931098 ~ 16967406 (+)
fgf8_1 fgf8,fgf8a,LOC107673879,LOC107716294,LOC107696243,LOC108442712,LOC107585369 coding upstream 140956 16916701 ~ 16922940 (+)
ldb1 ldb1,ldb1a,LOC108442788,LOC108444470,LOC107585322,LOC107673939,LOC107707596 coding downstream 9398 17077039 ~ 17107707 (+)
LOC103040130 NA coding downstream 41622 17109263 ~ 17130106 (+)
nsmce4a nsmce4a,LOC108262367,LOC107716332,LOC107688307,LOC107707575,LOC107585317 coding downstream 73030 17140671 ~ 17145888 (+)
LOC103040431 NA coding downstream 119500 17187141 ~ 17261572 (+)
unc5b unc5b,LOC107588651,LOC107707543,LOC107688303 coding downstream 412770 17480411 ~ 17575186 (+)
G217122 pcgf6 non-coding upstream 3315 17058330 ~ 17060581 (+)
G217109 NA non-coding upstream 54098 17009574 ~ 17009798 (+)
LOC111196035 NA non-coding upstream 165502 16883025 ~ 16898394 (+)
G216941 smap1,LOC107588664,LOC107694205,LOC107585328 non-coding upstream 344415 16560852 ~ 16719481 (+)
G216953 NA non-coding upstream 576358 16485902 ~ 16487538 (+)
G217140 NA non-coding downstream 196489 17264130 ~ 17264431 (+)
G217222 NA non-coding downstream 327398 17395039 ~ 17395249 (+)
G217313 NA non-coding downstream 709125 17776766 ~ 17777086 (+)
G217359 NA non-coding downstream 1032313 18099954 ~ 18161772 (+)
G217362 NA non-coding downstream 1049561 18117202 ~ 18124261 (+)
borcs7 borcs7 other upstream 56359 17004541 ~ 17007537 (+)
bcl11a bcl11a,bcl11aa,LOC107666449,LOC107601892,LOC107743494,LOC107655449,LOC107559339 other upstream 2283583 14722400 ~ 14780313 (+)
gsto1 gsto1 other upstream 2716563 14342232 ~ 14347333 (+)
spef1 spef1 other upstream 3313590 13740513 ~ 13750306 (+)
LOC103033819 LOC108426824,LOC108263419,LOC107725444 other upstream 3579525 13479176 ~ 13484371 (+)
LOC111195981 tacc2 other downstream 81701 17149342 ~ 17184251 (+)
pax2 pax2,pax2a,LOC107668824,LOC101463634,LOC107588637,LOC107716343,LOC107585307 other downstream 936612 18004253 ~ 18039352 (+)
eif4ebp2 eif4ebp2,LOC107564345,LOC107716353,LOC107668794,LOC107673927 other downstream 1244252 18311893 ~ 18317228 (+)
LOC103030769 LOC103030769 other downstream 1675565 18743206 ~ 18744327 (+)
cxcl12 cxcl12,cxcl12a,LOC107707253,LOC107673912,LOC106604225,LOC107588617,LOC107548639 other downstream 1769703 18837344 ~ 18847028 (+)

Expression


Co-expression Network