bag3 (bag3)



Basic Information


Item Value
gene id bag3
gene name bag3
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035921.1
NCBI id CM008324.1
chromosome length 46505145
location 14442676 ~ 14450871 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007252251.3
ATGGCACAATATTCAAGAGCGAGACTACAGCAGAGCATGAAAACACTGTCTCCTGTGGAAGCGATGGCTACGAATGACCCCCTGCCGCCAGGATGGGAGATCAAGATTGACCCTCAGACCGGCTGGCCGTTCTTTGTGGATCACAACAACCGCGTAACGACGTGGAACGACCCGAGACATGACTCTAAGAAGGTCATTCAGCTTTCTTCCAGTAGCCCATGTGCACCTACAGAGTTATCCCCTCAAGACAAGCACAAGACATTTATTCAGGAGATTAAACAGCCAACACTGCGCCAAGGTTACATCCCAATCCCTGTCATCCATGAAAATTTTGAGGCCAGGCCACATCCACTTTCCTATAAGCACCCAATGAACCCGCAAAACTTAAGAGCAGAAGGACGGACTCCATCCCCAACCCCCACGGCACACTGCCGGCCAAGATCTCCAGTGCAGTCCCCATCAGAGATTGATACTCACTGCTTGTCCTGCTCACCTGTTTCACAGGGACCTGAGATTCATCATGTCCACCATCCTTCTCAGGGGACACAGTCTCACACTAACTCCCTTCACCAGCCTTCCAGACCCAGCAGCACAGGCCTCCAGGCAGGCTACATTCCTATTCCTGTCATTCACGAGGGGGCAGGTGGCGTCCCACATACCCAGCTTAACCAGACCGTCCATCCAAAGCGCTTTACCCAGACAGAGTACCAACCCTCCTTTCACTGCCACCAACCAGAGGAGTGGAGCCGTGGCCCTGTGTTTGCCACGCGGGAAAAAATCCCAACCTATCGGGAGCAAGTGCCCATACAACTTGAGCAGAATCGCTCAGCCAGCCCTATCTTACATCCTCATACTGTAAGGGCTCAGGAGCCAGTCAGAGCACAGATCATGAGTGAGAGACCTCAGGCCCAGTCACATTTTGCACATACAGAGATCCCGCCCAAAGTTGAACAGTCATACGAGCAGCCTGTCAGCCCAGCAACGGAGATTCCTATTAGGAGAGTCAGTGAAGCACAGCCGCCTGAAGCACATCCTGTATCACCAACCACACATCAGCCCATACAGGAATTTGAACAGGCACCTATACAACAGTTTGAGCTACAACCTGAGCAACTACCACAACAGATGCCTGAGACTACCAATATCTACATGCAGGTACCTTTGACATCAGAACCTCAAGACGCTACTCCACAACCAGAAGTTTTACCTCCACAAGCTCAGCCTGAAGAAAAGGCAGAGCCATGCTCAGCCCACCCGGGACTGGTAAAAGTACAGGCAATATTGGAGCGGGTGGAGAAACTGGCACAGGATGTGAAGTGTTTTGATGGGAGAAAGAATGATAAAAGATATCTGATGCTGGAGGAGTTTTTGACCAAAGAATTGCTGGCTCTGGACTCAGTAGACCCAGAAGGACGTATAGACGTGCGCCAGGCTCGGCGTGATGGCGTTCGCAGAGTACAAACCATTCTTGAGGAACTAGAGGCCCTCAGTGAAAGCTGCACTGAAACTACTAGCTCAGCTCAGAAAGGAGAGCCTAGCTTGATTGGCCAGGCAGACATGGAGAAGGCCAAGGAGATCTCGTAACCTCAAACCGAAGCCCTACAATGAAAGTACAAAAACAAATCACATCTCCTCAGTCTCCTTCGCCTATTATCACTTGCATGCACAATTAATTTAACTGTTCTGTTGGCTGAAAATGAATATAATTTGTTTACCGAGTGCAATTATGTGTGCTGTTATGTGATGCTGCTGTTGTGGAATTTCACCGTGCAAGTGTCTTGTAGCAGGACCATAGTGGTGACCTTGTAGTGACTTGGTTTCAACCTGAAACTCAGTCTCGAATAAGAGGCctttaataaaatgcaaatgctttatttttgctTCTACTTTTGGGAACGCA

Function


symbol description
bag3 Predicted to enable adenyl-nucleotide exchange factor activity; chaperone binding activity; and heat shock protein binding activity. Acts upstream of or within heart contraction; locomotory behavior; and skeletal muscle tissue development. Located in Z disc. Is expressed in fast muscle cell; heart; muscle; and slow muscle cell. Used to study dilated cardiomyopathy and muscular dystrophy. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 1HH and myofibrillar myopathy 6. Orthologous to human BAG3 (BAG cochaperone 3).

NR:

description
BAG family molecular chaperone regulator 3-like

GO:

id name namespace
GO:0060047 heart contraction biological_process

KEGG:

id description
K09557 BAG3; BCL2-associated athanogene 3

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007252251.3 True 1900 mRNA 0.49 4 14442676 14450871

Neighbor


gene id symbol gene type direction distance location
LOC103031316 LOC108426755 coding upstream 11935 14418969 ~ 14430741 (+)
atoh7 atoh7,LOC108426756,LOC107666420,LOC107726941,LOC107601814,LOC107655428,LOC107743508 coding upstream 31253 14410095 ~ 14411423 (+)
LOC103031627 LOC108426796,LOC107559326,LOC107655434,LOC107743509,LOC105911640,LOC106576688,LOC103353499 coding upstream 47608 14382712 ~ 14395068 (+)
calhm2 calhm2 coding upstream 63502 14373831 ~ 14379174 (+)
LOC103038684 LOC103038684,LOC108426744 coding upstream 69849 14367304 ~ 14372827 (+)
inpp5f inpp5f,LOC107666413,LOC107726944 coding downstream 3145 14454016 ~ 14479060 (+)
sec23ip sec23ip,LOC107655440,LOC107666414,LOC107743502,LOC107601884 coding downstream 42982 14493853 ~ 14505846 (+)
pcbd1 pcbd1,LOC107743500,LOC107601888,LOC107655445,LOC107559335 coding downstream 157304 14608175 ~ 14612568 (+)
LOC111195974 NA coding downstream 188995 14639866 ~ 14640543 (+)
fancl fancl,LOC107585345 coding downstream 1065867 15516738 ~ 15542681 (+)
G216435 NA non-coding upstream 39212 14402585 ~ 14403464 (+)
G216410 NA non-coding upstream 87857 14353101 ~ 14354819 (+)
G216408 NA non-coding upstream 90763 14351568 ~ 14351913 (+)
G216354 LOC108426801,LOC107726962 non-coding upstream 177327 14255407 ~ 14265349 (+)
G216441 mcmbp,LOC107743503,LOC107559330,LOC107655439,LOC107726945 non-coding downstream 36888 14487759 ~ 14488523 (+)
G216505 NA non-coding downstream 163275 14614146 ~ 14616451 (+)
G216508 NA non-coding downstream 166447 14617318 ~ 14618083 (+)
G216507 NA non-coding downstream 172789 14623660 ~ 14630795 (+)
G216520 NA non-coding downstream 192047 14642918 ~ 14645082 (+)
gsto1 gsto1 other upstream 95343 14342232 ~ 14347333 (+)
spef1 spef1 other upstream 692370 13740513 ~ 13750306 (+)
LOC103033819 LOC108426824,LOC108263419,LOC107725444 other upstream 958305 13479176 ~ 13484371 (+)
trnay-gua_11 NA other upstream 1126514 13316075 ~ 13316162 (+)
trnay-gua_10 NA other upstream 1127476 13315112 ~ 13315200 (+)
bcl11a bcl11a,bcl11aa,LOC107666449,LOC107601892,LOC107743494,LOC107655449,LOC107559339 other downstream 271529 14722400 ~ 14780313 (+)
borcs7 borcs7 other downstream 2553670 17004541 ~ 17007537 (+)
LOC111195981 tacc2 other downstream 2698471 17149342 ~ 17184251 (+)
pax2 pax2,pax2a,LOC107668824,LOC101463634,LOC107588637,LOC107716343,LOC107585307 other downstream 3553382 18004253 ~ 18039352 (+)
eif4ebp2 eif4ebp2,LOC107564345,LOC107716353,LOC107668794,LOC107673927 other downstream 3861022 18311893 ~ 18317228 (+)

Expression



Co-expression Network