hsd17b12 (hsd17b12,hsd17b12a,LOC107661451,LOC107696265,LOC107573907,LOC107716735,LOC107753600)


Basic Information

Item Value
gene id hsd17b12
gene name hsd17b12,hsd17b12a,LOC107661451,LOC107696265,LOC107573907,LOC107716735,LOC107753600
gene type misc
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 20084428 ~ 20100250 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>TU101364
GTTAGAGGAGTTGTGGGGGTGTGATGCCACAACCTGCTTATAAAGGGGCTCGCACGTTGTAGGCTGTGAAATCAGTGCACGTCGCCTAATTTTCAGTGGGTCAGGCCGCCGTCCGCATAGAGGTGTTCAGCGAGCTGGAGAAAATGCTGCATGGGGCCGAGTCTGTTCTGCTGTGGGTCGGGGCGCTCACCACGGCCTCTCTGGCTCTCTGGATCCTCTACCGACTCCTCTCCGGCTTCAGGATATGGGTGATGGGCAACGGAGACCTGCTGTCCCCCAAACTGGGCAAATGGGCAGTGGTGACGGGAGCCACAGATGGAATTGGGAAATCCTATGCGGAGGAGCTTGCTCGACGAGGATTCTCCATGATGCTTATCAGCCGCACTCAGGAGAAGCTGGATGACGTTGCACAGTCCTTggAGCGTCGCTATAAGGTGGAGACCAAGACAGTTGCTGTAGATTTTGGTCAGGTTGACATCTATCCTAAGATTGAAACGGCGCTAAGTGGCCTTGAAATTGGAGTGCTTGTGAACAATGTAGGCATTTCTTACCCCTATCCAGAGTTTTTCCTGCACATCCCTGATCTTGACAATTTCATCAACACTATGATCAATGTCAATATCACCTCAGTGTGTCAGATGACGCGTCTGGTGTTGCCCAGAATGGAAGCGAGAGCAAAAGGTGTTATTCTCAACATCTCTTCTGCCAGCGGCATGTACCCAGTCCCACTGCTGACCGTCTACTCCTCCACCAAGGCAAGTACAACTCCATCT
>TU101365
TAGTTTTAAAGTTGTGTTTATGACCTCTCTTTAGGCTTTTGTCGATTTCTTCTCCCGTGGACTCCAAGCAGAGTACAAGAGCAAGGGAATAATCATCCagAGTGTGCTGCCTTTCTTCGTGGCCACCAAAATGACAAAGATTAGGAAACCCACTCTGGATAAGCCCACTCCTGACCGCTATGTAGCTGCTGAGCTGACCACCGTGGGGCTGCAGGACCAGACCAATGGCTACTTCCCTCATGCAGTCATGGGCTGGCTGACCACTGTTCTGGTTCCCATCAATTTGGTCATTTACTTTGGCATGCGTATGAACAAGGCTCAGCGAGGCGGCTACCTCAGAAGGAGAAAGCTGAGATAGGTTGCAGTGATTGCCTAAAACAGGGTTCTTCAATCCTGGTCCTACCACCCCCATCCCCTCCCCACCCTGGCCTGCATATGTATGGCTTTTCCTTTTACCACTACACCCGATTAATCTAATCAGCTCATTATCAAGTCCTTTCGGagttgcagtgtgtgtttgtgtgagttaAAGCAGGCAATCCTCTAAAaggtgctgggtgggtgggtaggtaggtaggtgccAGGACCCAGATTGAAGAACACTGGCCAAAAGGGAAAAGTGCTTTTTCCTTTCTGTTTGTCCATCAGCTTAGTTTGGATATGACTGCCTGACTCTTGTATCAGTGTTCGAGTAGTTGTGTGTGGAGGCTTTGAATACTGCCTTGTTTAAGtagcttttttgtgtgtttttttatataaataatgttgtAAGAGCTACTGACTGCACAGATGTCACTGATGCATCCTGAAATGAAGTAGTTCAGACTGTGCCTTAAACCTGGTGAGATTTCCTATAGTTTGCTGTTTTGATTTGGGAGTGGAAGTGGGATATAGCTTTTCTGTACAGGGTCTAAAGAGTGCTGCACTGGTGCATGAAGGGCTCACTTTTCACTGCTGTTGTAAGCAGATGGTATTTGAATGGAAGGTGGGGATgatttatacatattttcatGAGTATATAAAAGCCACTCATGCACCATGTTTGTTGTTCACTGATGCCAGTTCCCTGTCGTGTTTGTTTACTATGAAGAAGgtgaatttataaaaaatattttttctacagtTCTTGAACGATCAAATGAGAAATgacatttttaatctttttcatgtttttgtacCATTTATTACAACCTCTTGTATTTATGAAATCAGTGGTGGGGGGCTtttggtgttttatttttactatattattGCTACTAGATTCAATGGTGCTTTTTATAATGAGCCACTTTGGACACACCTATTGTCAATCTCTGATCATTCAGAATGTGCCTTATGGTAATAATCAGGAAATTGGTCAGGATTATTAAAAGCTGCTGGTCTATCTCAGACATAGCAATGCACTTACTTGCCTtactttctttccctttttaaCTTTCCACCAAAGAGCAAATATGCCATActgtatctatttatttttataggaGGTCTCATTTTAGCCATTCTCTCTGGCTTAGGGCTTAGATCTCTGTACAATTTTGTCTGGACCAAAGCCAGGTCAAATTGTAATGCTCAGGTGTTGCAGCAAATGGGAAAACTTGAATTTTTACCTTTCAACAtatttaagaacaaaaacaaatgtgtgCCTTTGTTCCTTAATTATTGTTCTTGTTAATAAAATTACCTGTCACA
>XM_007244252.3
TTAGAGGAGTTGTGGGGGTGTGATGCCACAACCTGCTTATAAAGGGGCTCGCACGTTGTAGGCTGTGAAATCAGTGCACGTCGCCTAATTTTCAGTGGGTCAGGCCGCCGTCCGCATAGAGGTGTTCAGCGAGCTGGAGAAAATGCTGCATGGGGCCGAGTCTGTTCTGCTGTGGGTCGGGGCGCTCACCACGGCCTCTCTGGCTCTCTGGATCCTCTACCGACTCCTCTCCGGCTTCAGGATATGGGTGATGGGCAACGGAGACCTGCTGTCCCCCAAACTGGGCAAATGGGCAGTGGTGACGGGAGCCACAGATGGAATTGGGAAATCCTATGCGGAGGAGCTTGCTCGACGAGGATTCTCCATGATGCTTATCAGCCGCACTCAGGAGAAGCTGGATGACGTTGCACAGTCCTTggAGCGTCGCTATAAGGTGGAGACCAAGACAGTTGCTGTAGATTTTGGTCAGGTTGACATCTATCCTAAGATTGAAACGGCGCTAAGTGGCCTTGAAATTGGAGTGCTTGTGAACAATGTAGGCATTTCTTACCCCTATCCAGAGTTTTTCCTGCACATCCCTGATCTTGACAATTTCATCAACACTATGATCAATGTCAATATCACCTCAGTGTGTCAGATGACGCGTCTGGTGTTGCCCAGAATGGAAGCGAGAGCAAAAGGTGTTATTCTCAACATCTCTTCTGCCAGCGGCATGTACCCAGTCCCACTGCTGACCGTCTACTCCTCCACCAAGGCTTTTGTCGATTTCTTCTCCCGTGGACTCCAAGCAGAGTACAAGAGCAAGGGAATAATCATCCagAGTGTGCTGCCTTTCTTCGTGGCCACCAAAATGACAAAGATTAGGAAACCCACTCTGGATAAGCCCACTCCTGACCGCTATGTAGCTGCTGAGCTGACCACCGTGGGGCTGCAGGACCAGACCAATGGCTACTTCCCTCATGCAGTCATGGGCTGGCTGACCACTGTTCTGGTTCCCATCAATTTGGTCATTTACTTTGGCATGCGTATGAACAAGGCTCAGCGAGGCGGCTACCTCAGAAGGAGAAAGCTGAGATAGGTTGCAGTGATTGCCTAAAACAGGGTTCTTCAATCCTGGTCCTACCACCCCCATCCCCTCCCCACCCTGGCCTGCATATGTATGGCTTTTCCTTTTACCACTACACCCGATTAATCTAATCAGCTCATTATCAAGTCCTTTCGGagttgcagtgtgtgtttgtgtgagttaAAGCAGGCAATCCTCTAAAaggtgctgggtgggtgggtaggtaggtaggtgccAGGACCCAGATTGAAGAACACTGGCCAAAAGGGAAAAGTGCTTTTTCCTTTCTGTTTGTCCATCAGCTTAGTTTGGATATGACTGCCTGACTCTTGTATCAGTGTTCGAGTAGTTGTGTGTGGAGGCTTTGAATACTGCCTTGTTTAAGtagcttttttgtgtgtttttttatataaataatgttgtAAGAGCTACTGACTGCACAGATGTCACTGATGCATCCTGAAATGAAGTAGTTCAGACTGTGCCTTAAACCTGGTGAGATTTCCTATAGTTTGCTGTTTTGATTTGGGAGTGGAAGTGGGATATAGCTTTTCTGTACAGGGTCTAAAGAGTGCTGCACTGGTGCATGAAGGGCTCACTTTTCACTGCTGTTGTAAGCAGATGGTATTTGAATGGAAGGTGGGGATgatttatacatattttcatGAGTATATAAAAGCCACTCATGCACCATGTTTGTTGTTCACTGATGCCAGTTCCCTGTCGTGTTTGTTTACTATGAAGAAGgtgaatttataaaaaatattttttctacagtTCTTGAACGATCAAATGAGAAATgacatttttaatctttttcatgtttttgtacCATTTATTACAACCTCTTGTATTTATGAAATCAGTGGTGGGGGGCTtttggtgttttatttttactatattattGCTACTAGATTCAATGGTGCTTTTTATAATGAGCCACTTTGGACACACCTATTGTCAATCTCTGATCATTCAGAATGTGCCTTATGGTAATAATCAGGAAATTGGTCAGGATTATTAAAAGCTGCTGGTCTATCTCAGACATAGCAATGCACTTACTTGCCTtactttctttccctttttaaCTTTCCACCAAAGAGCAAATATGCCATActgtatctatttatttttataggaGGTCTCATTTTAGCCATTCTCTCTGGCTTAGGGCTTAGATCTCTGTACAATTTTGTCTGGACCAAAGCCAGGTCAAATTGTAATGCTCAGGTGTTGCAGCAAATGGGAAAACTTGAATTTTTACCTTTCAACAtatttaagaacaaaaacaaatgtgtgCCTTTGTTCCTTAATTATTGTTCTTGTTAATAAAATTACCTGTCACAA

Function

symbol description
hsd17b12a Predicted to enable estradiol 17-beta-dehydrogenase activity. Predicted to be involved in estrogen biosynthetic process and fatty acid biosynthetic process. Predicted to act upstream of or within steroid biosynthetic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be integral component of membrane. Is expressed in several structures, including EVL; digestive system; integument; nervous system; and pleuroperitoneal region. Orthologous to human HSD17B12 (hydroxysteroid 17-beta dehydrogenase 12).
hsd17b12 Enables long-chain-3-hydroxyacyl-CoA dehydrogenase activity and long-chain-fatty-acyl-CoA reductase activity. Predicted to be involved in long-chain fatty-acyl-CoA biosynthetic process. Predicted to act upstream of or within extracellular matrix organization and positive regulation of cell-substrate adhesion. Part of fatty acid elongase complex.

NR:

description
very-long-chain 3-oxoacyl-CoA reductase

GO:

id name namespace
GO:0006703 estrogen biosynthetic process biological_process
GO:0055114 oxidation-reduction process biological_process
GO:0005789 endoplasmic reticulum membrane cellular_component
GO:0016021 integral component of membrane cellular_component
GO:0004303 estradiol 17-beta-dehydrogenase activity molecular_function

KEGG:

id description
K10251 HSD17B12, KAR, IFA38; 17beta-estradiol 17-dehydrogenase / very-long-chain 3-oxoacyl-CoA reductase

RNA

RNA id representative length rna type GC content exon number start site end site
TU101364 False 773 TUCP 0.53 8 20087418 20100250
TU101365 False 1692 lncRNA 0.41 3 20084429 20086739
XM_007244252.3 True 2413 mRNA 0.45 11 20084428 20100249

Neighbor

gene id symbol gene type direction distance location
alkbh3 alkbh3 coding downstream 3093 20073506 ~ 20081335 (-)
c8h11orf96 si:ch1073-281m9.1,cunh11orf96,LOC103025886,LOC107696240,LOC107661503,LOC107575890,LOC107580776 coding downstream 22353 20060386 ~ 20062075 (-)
ticrr NA coding downstream 33143 20037455 ~ 20051285 (-)
LOC103024527 fam19a5b,LOC103024527,LOC108428378,LOC107696241,LOC107753604,LOC107598818,LOC108274593 coding downstream 111770 19939635 ~ 19972658 (-)
LOC103030439 ube2q2,LOC108436947,LOC107696278,LOC105015542,LOC107661444 coding downstream 312103 19762795 ~ 19772325 (-)
LOC103045029 LOC108428372 coding upstream 92275 20192525 ~ 20206698 (-)
LOC103029688 si:ch1073-174d20.1,dbndd1,LOC108428370,LOC108275320,LOC107723994,LOC107742629,LOC107559144,LOC107570651 coding upstream 143116 20243366 ~ 20253823 (-)
ankrd27 ankrd27 coding upstream 740254 20840504 ~ 20863315 (-)
LOC103032734 LOC108428429,LOC108275416,LOC107577622,LOC107566260,LOC107682256 coding upstream 769437 20869687 ~ 20877379 (-)
trnat-agu_2 NA coding upstream 795853 20896103 ~ 20896176 (-)
G75208 api5,LOC107753602,LOC107661449 non-coding downstream 49669 20032610 ~ 20034759 (-)
G75106 NA non-coding downstream 211747 19871142 ~ 19872681 (-)
G75093 NA non-coding downstream 279458 19804766 ~ 19804970 (-)
G75092 NA non-coding downstream 284803 19799385 ~ 19799625 (-)
G75081 NA non-coding downstream 337983 19745564 ~ 19746445 (-)
LOC107197502 NA non-coding upstream 1462 20101712 ~ 20129570 (-)
G75223 NA non-coding upstream 48439 20148689 ~ 20151436 (-)
G75224 rfwd3,LOC106584535 non-coding upstream 53297 20153547 ~ 20158204 (-)
G75232 LOC108428438,LOC108274991,LOC107559147 non-coding upstream 80900 20181150 ~ 20186487 (-)
G75265 NA non-coding upstream 172525 20272775 ~ 20276444 (-)
G75207 api5,LOC107696269,LOC107753602 other downstream 52401 20027162 ~ 20032027 (-)
G75100 LOC108436948,LOC108275266 other downstream 218446 19859694 ~ 19865982 (-)
G74838 wasl,LOC105896696,LOC108275301 other downstream 1011540 19070938 ~ 19072888 (-)
LOC103034453 LOC108436916,LOC107753633,LOC107659484,LOC107573489,LOC107752304,LOC108181664,LOC107598834 other downstream 1076062 18992668 ~ 19008366 (-)
G74791 NA other downstream 1143964 18939174 ~ 18940464 (-)
LOC103032014 maf,LOC108428434,LOC108274756,LOC102790406,LOC102298902,LOC101477682,LOC102192535,LOC101173775,LOC100702616,LOC107663990,LOC107565340 other upstream 522391 20622641 ~ 20748208 (-)
gatd1 pddc1,LOC102788149 other upstream 965069 21065319 ~ 21071246 (-)
LOC111193105 LOC102794092,LOC108274651,LOC107571202,LOC108428364 other upstream 1169254 21269504 ~ 21273017 (-)
LOC103024007 LOC108428399 other upstream 2342486 22442736 ~ 22574013 (-)
LOC103033738 LOC103033738,LOC108444230,LOC106560753,LOC105008418,LOC108274439,LOC107549618,LOC107686877 other upstream 3224327 23324577 ~ 23366216 (-)

Expression


Co-expression Network