tsg101 (tsg101,tsg101a)


Basic Information

Item Value
gene id tsg101
gene name tsg101,tsg101a
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 10212563 ~ 10221827 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007228053.3
CTTAGCGACGGAAAGAGGTCGATCTGTCCATTTTGGCAGAGTGCACTTGCTTTATTTACCTTTCCTGATGAGCTAGCTGTACTCTGAGTTTAGTGTAAGTGTCAGGAATAGATCTGAAACGGCTTTAACTCGAGCTGTGTGGAGTATCAGTCCGGTATCCGTCGTGTGCTCGGGTTAAAGCCCGGGTTTAGGGGAGTTTATCGGGGGGACCGTCTCCTGGCCCTGGCTGAGTTTAGCCGGGGACCAGGCCAGCGCTGCGGAACTAGCTGGGCAACCATTACAGCTCCATACACCCGTTATTAATAAAAGCCGGGATTAActaaattacagtttatttattgaAGACTGTGAGAGAGTTTAGGGGCTCAGCTATGGCGGTTGTCAACGAAGGCGCGCTTAAAAAGATGCTGAAGCAATATAAATACCGTGACCTCACTGTACGTGAGATAACGAATGTCATCCTGCAATACAAAGATCTGAAACCTCTGATGGATGCTTATGTGTTCAATGATGGATCGTCAAGGGAGTTGATGAGTTTAACAGGGACAGTGCCAGTAAGCTATAGAGGAAATGTGTATAATATCCCTGTGTGTCTATGGCTGTTGGACACATATCCCTACAACCCTCCCATATGTTTTGTGAAACCTACCAGCGCAATGATGATCAAGACTGGGAAACATATTGATGCCAATGGCAAGATTTACCTTCCCTATCTCCATGAATGGAAACATCCGCAGTCTGACCTGTATGGTCTGATCCAGGTCATGATTGTTGTTTTTGGAGAGGAGCCTCCTGTTTTCTCACGACCCACAACTCAGCCCCCCTATCAGTCCTTCCAGGCCACTGGGCCCCCAAATCAATCTTACATGCCTGGAATGCCTGCTGTGTCTGGTTATGGACCAAACCCAAATCCATgTGGGTATCCAGGCTATCCTTATCCTGGAGGGTCTACATATCCTGCTTCTGGGGGCCCTACACACTACCCGTCCCAGCCTCCAGTCACTACTGTGGGGCAGAGTCGAGATGGCACCATCGGAGAGGACACTATCCGTGCCTCGCTCATCTCGGCTGTGAGCGATAAACTCCGCTGGAGGATGAAGGAGGAGATGGATAGGGCTCAGGCTGAGCTGGATGCTCTCAAGCGTACAGAGGAGGACCTGAAGAAAGGCCACCAAAAGCTGGAGGAGATGGTCTCTCGTCTGGACCAGGAAGTGgCTGAGGTGGACAGGAATATTGACCTGCTCAAGAAGAAGGATGAGGAACTGACAGAAGCTCTGGAGAAGATGGAGAATCAGTCAGAGAACAATGATATTGATGACGTAATTGTTCCCACAGCGCCGCTCTATAAACAGATCCTGAATCTGTATGCTGAGGAGAATGCCATTGAGGACACCATATTCTACCTTGGGGAGGCTCTACGCAGAGGCGTCATCGACTTGGAGGTCTTTCTCAAGCATGTGCGACTGCTGTCCCGTAAGCAGTTCCAGCTGAGAGCACTGATGCAGAAAGCCCGAAAGACTGCCGGACTCAGCGACCTCTACTGATCCCACTGCCACCTGATCCCCCAccttgttttatgttttctttccCTTACTATGTTTTACATAGTTGTCAACAGCTTCCCTTATAAACTGATGCCTACTTATATCCTTTGGATTCTGGCAAATATAGCATAACATTGATGAATCCTTCAAGTTATCTATGTTGAAATcagataaaattttaaaatcagaAATGAAGCACAACAGTGATTGACTGACTGTTTAACTGGCTGACCAACTAGGGACAAAGTCACAGGGGTGACTTTCTGTTTCTTCATGCATgtaatgcacattttttttctgtcttagAGCTTCTTTACATCTTCATCTTTTGGTTATTATATCAAAATGTGTCAGATttgttgattgttttttttttgcagtactgACTCCAAAATGTAGCAAATGACAAACTGCTGAATGACTGCTCCACACtccttacatttttgtttttgggacaagaaaatacttatttaattttagaaaggaACTCTTTAATGCAATGTGAGCTTTTGTATCTCAgcgattttattttactgtttctgaCTGAGTATTTATGTTTTTCAACTGTGCTGTCCTGGGGTCGACCTGCTGCGTCCTGTTCCTGAATTGTTGCTATAATTGTACAACTGTCGTTCATGTAGctatttaaactgaattattcGTCTGACATTTCAAGTGTTACAAATTTAGAACGGTTCCAGAGCATTTGCACTCAAATTTCTGAGTGAGAAATTGTGTGTACGTGTAggcatgtatgtgtgtacaaGTATTCATACAGGTCTGCTTAGTTTGACTGACTCCAGCATCAACAATGGAATGAAgatttctttattaattcattcaaaaaggttttaaatgacttttgacaaaataatagagaaaaaaaaatctatgtgtgttttttttttttttagtgcgtTTTGGGTGggcaactttattttatttgattgagaAGATCCTATTACAAAGATTCTTCTTACTTTTTCCTTCTTGTTTTCAGATCTTTAGTTGTTAATATCTTCTGCTCAATAAAATCAGGATAATTTGG

Function

symbol description
tsg101a Predicted to act upstream of or within cellular protein modification process and protein transport. Predicted to be located in endosome. Human ortholog(s) of this gene implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and prostate cancer. Orthologous to human TSG101 (tumor susceptibility 101).
tsg101 Enables several functions, including protein homodimerization activity; ubiquitin protein ligase binding activity; and virion binding activity. Involved in several processes, including positive regulation of exosomal secretion; positive regulation of viral life cycle; and regulation of protein kinase activity. Located in several cellular components, including endosome; extracellular exosome; and nucleolus. Part of ESCRT I complex. Implicated in breast cancer; breast carcinoma; cervix carcinoma; endometrial adenocarcinoma; and prostate cancer. Biomarker of breast cancer and ovarian cancer.

NR:

description
tumor susceptibility gene 101 protein

GO:

id name namespace
GO:0006464 cellular protein modification process biological_process
GO:0015031 protein transport biological_process

KEGG:

id description
K12183 TSG101, STP22, VPS23; ESCRT-I complex subunit TSG101

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007228053.3 True 2592 mRNA 0.43 10 10212563 10221827

Neighbor

gene id symbol gene type direction distance location
LOC103047796 NA coding upstream 67 10207709 ~ 10212496 (+)
hras hras,rash,LOC107562835,LOC103357265 coding upstream 6441 10185737 ~ 10206122 (+)
irf7 NA coding upstream 139462 10065416 ~ 10073101 (+)
thg1l thg1l,LOC103154062,LOC106912903,LOC107751338 coding upstream 234739 9974224 ~ 9977824 (+)
LOC103044029 LOC108442474,LOC108275029,LOC107680923,LOC107660187,LOC107587072 coding upstream 255035 9910406 ~ 9957528 (+)
igsf22 igsf22 coding downstream 753894 10975721 ~ 11000591 (+)
spty2d1 spty2d1 coding downstream 807659 11029486 ~ 11034828 (+)
LOC103022764 uevld,LOC108275186 coding downstream 815673 11037500 ~ 11048398 (+)
th th,LOC108274586 coding downstream 883827 11105654 ~ 11116630 (+)
LOC103024122 LOC108439251,LOC100136550,LOC100304637,LOC107675272 coding downstream 901352 11123179 ~ 11132277 (+)
LOC111193092 NA non-coding upstream 113418 10097259 ~ 10099145 (+)
G72617 NA non-coding upstream 153677 10058685 ~ 10058886 (+)
G72615 NA non-coding upstream 154745 10057483 ~ 10057818 (+)
G72612 NA non-coding upstream 183717 10028483 ~ 10028846 (+)
G72606 NA non-coding upstream 234141 9977975 ~ 9978422 (+)
G72752 NA non-coding downstream 576165 10797992 ~ 10798845 (+)
G72753 NA non-coding downstream 577719 10799546 ~ 10801772 (+)
G72766 NA non-coding downstream 786722 11008549 ~ 11015607 (+)
G72871 NA non-coding downstream 962839 11184666 ~ 11184981 (+)
G72875 NA non-coding downstream 1000947 11222774 ~ 11223004 (+)
G72621 NA other upstream 130423 10078579 ~ 10082140 (+)
LOC103043718 LOC103043718,LOC108442465 other upstream 242521 9968506 ~ 9970042 (+)
G72281 LOC107754548,LOC108274935,LOC107754545,LOC107754498 other upstream 1063144 9142899 ~ 9149419 (+)
LOC103030246 pcdh2ab8,pcdh2ab10,pcdh2ab12,LOC108430950,LOC101884096,LOC108274577,LOC107588388,LOC108430926,LOC108430925,LOC108430922,LOC108275110,LOC108430948,LOC108275111,LOC107588302,LOC107660888,LOC107754492,LOC107655665 other upstream 1176537 8869128 ~ 9036026 (+)
G71788 LOC105418110,LOC105418502,LOC106676625,LOC102305489,LOC102201812 other upstream 3327022 6881587 ~ 6885541 (+)
LOC103022150 brsk2a,brsk2b,LOC107707552,LOC107675281,LOC107600443 other downstream 51092 10272919 ~ 10626964 (+)
LOC103043719 NA other downstream 2649657 12871484 ~ 12897931 (+)
G73533 NA other downstream 4427002 14648829 ~ 14649551 (+)
rpgrip1l rpgrip1l other downstream 4669707 14891534 ~ 14921003 (+)
svip svip other downstream 5350475 15572302 ~ 15577533 (+)

Expression


Co-expression Network