wwox (wwox,LOC107559152)


Basic Information

Item Value
gene id wwox
gene name wwox,LOC107559152
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 20289830 ~ 20632543 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007244266.3
GTGTCCGTGCAGTGGTGGAGAGTGCTGCTGtgggtctgctgctgctggtggtggagTGGAGCTGTTCTGACTGAGAGACACAGAAGCGGCTGAATTAGAAACTCTTACAGGAGAACCGCACAGCGCAATGGCTGCTCTTAAATACGCGGGAATGGACGATACTGACAGCGAGGACGAGCTGCCCCCCGGCTGGGAGGAGAGATCCACCAAGGATGGCTGGGTTTATTATGCCAAtcaCGAGGAGATGAAAACACAGTGGGAGCATCCTAAAACTGGAAAGAAGAAACGCTGTGCTGGAGatcTGCCGTACGGGTGGGAACAGGAGTTGGACGACAAGGGTCAAGTCTTTTATGTTGATCACATCAACAAGAGAAAGACGTACTTCGATCCTCGGCAGGCCTTCACCATAGAGGATGTACAAGTAAAGCCCAAGCGTTATGATGGAAACACTGCTGCCCTGGAGATTCTACAGGGTCAGGATCTCTCCAACAAGGTCATAGTCATTACTGGAGCCAATTCTGGTGTCGgTTTTGAGACGGCGCGCTCCTTCGCTCTTCATGGGGCTCATGTGATCTTGGCCTGCCGGAATAAAGCTCGCAGCAGTAAAGCAGTTAGTCTGATTCTAGAGGAGTGGCACAAAGCTCGCGTTGAGGCCATGACACTGGACCTGGCCTCGTTGAGAAGTGTTCAAGAGTTTGCAGAGGCCTTTAAAGCACGGAAACTgcCTCTGCATATTCTGGTGTGTAATGCGGCAGTATCTACACAGCCCTGGTGTTTGACTGAGGACGGGCTGGAATCCACCTTCCAGATCTGCCACCTGGGCCACTTCTACCTGGTGCAGCTGCTGCAGGATGTGCTGCGGCGGTCAGCTCCTGCTCGTGTGGTGGTGGTGTCCTCTGAATCCCACAGGTTCACAGAGCTGCTGGACTCGTGTGGTAAAGTGGACTTGGCTCTGCTCTCTCCGCCTCAGAAGGAGTACTGGTCCATGCTGGCCTACAATAGAGCCAAACTCTGCAACATCCTGTTCTCCAATGAGCTGAACCGCCGCCTGTCTCCGCACGGGGTCACCTCCAACGCAGTGCACCCTGGGAACATGATGTATACGTCCATCCATCGCAGCTGGTGGCTCATGACCTTCCTCTTCACCCTGGCACGACCGTTCACCAAGTCTATGCAACAGGGTGCGGCCACCACCGTGTACTGCGCAGTGGCTCCGGAGCTGGAGGGACTGGGAGGGATGTACTTCAACAACTGCTTCCGCTGTCTTCCGTCTCAGCAGGCCCAGGATCCCTCCTCCGCCCTCAGCCTGTGGGAGCTCAGCGAGAGGCTGGTCCAGGAGAGGTCCACCAACCCTCAGCCAGTGTAACCTCAGGATCCCGTCGCGTGCCAGTGACCCCGACACCTTCCGTGCCCTGCCGCACGTTTTCCATCACCAGGAAGTGAAGGGgactgtgtgttttatatttgggaaatatacagtatacactactgtactcactgtacaaaaatacaaacaaaaaaacaacagccaAATCCTTTAGTCTGCACCTTCAGTGTCCACTGTCACCGTTCGCCATAAACCAAGCCTGGAGAGTCTGTAGGAGCTAGCACTGTGTAACGTCACTGTATATATTTCCCAGGCCGTTCCAGATTCCTCACCTTTTGTTCCTCACATGAGCTATAGAACACCGTCTAGAACACTGTTCTCTAATACGGCTCTCTAAACATCGATCACCACACGTTCCAGCTAGGGGCTCTACGTTATAGCAAATAcacttagaaaaaaatagaacatcatCTCACAATCTTAAACTACACAATTTTTAATCTTTGAATTCGAGTTCTGTTGAAATAGCTGGGAATTCTCGTTCTCAAGGTCCATCCATCCCTTTGTACAGATTGAATTAAGAGAATGAGTAGATGAGTGCACTAAAGAAGCTACAAAGAAGTAGTGGAGGAAGTAGTGGAGGAAGTAGTGGAagagtgtatgtatgtgtgtgtatgtctgtgtgtgtgtgtgtgggtgggcgGGTGTGAATGCGTACGAGAGTGGTTTCCTATTTACACATAAGACCACTGAAGTTCCTACAAATCTGCCTGTATAGATATGCTGTACATGATACACATCAGGTGATGTTCTAATGCGCTTTATGTTTCTGTAGATTCTGTAGATTAGTAGAATTCACGACCCCCAATCTGCCGAGAGACTCCCGATCCAAACTATGAATTTTCGAACTTTTACAAaatgctatgctaatgctaattacaATGAAGCAGCATCTCTGAGGAGAACAGGAGGGCCAGTGCTggct

Function

symbol description
wwox Predicted to enable oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor. Acts upstream of or within cellular calcium ion homeostasis. Predicted to be located in cytoplasm and nucleus. Is expressed in cranial nerve II; gut; heart; and presumptive cardiac ventricle heart tube. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 12; developmental and epileptic encephalopathy 28; esophageal cancer; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human WWOX (WW domain containing oxidoreductase).

NR:

description
WW domain-containing oxidoreductase

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0016491 oxidoreductase activity molecular_function

KEGG:

id description
K19329 WWOX; WW domain-containing oxidoreductase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007244266.3 True 2312 mRNA 0.50 9 20289830 20632543

Neighbor

gene id symbol gene type direction distance location
LOC103030013 LOC108428369,LOC107701578,LOC107742623,LOC107559153,LOC107723981,LOC107570647,LOC107688789 coding upstream 5157 20278577 ~ 20284673 (+)
LOC103030550 LOC108428435,LOC108274760 coding upstream 13275 20253846 ~ 20276555 (+)
tdrd12 NA coding upstream 59830 20209281 ~ 20230000 (+)
LOC103028218 LOC108428438,LOC108274991,LOC107559147 coding upstream 98213 20160901 ~ 20191617 (+)
rfwd3 rfwd3,LOC107754982,LOC107559137 coding upstream 129728 20148662 ~ 20160102 (+)
faap24 faap24 coding downstream 244874 20877417 ~ 20880566 (+)
LOC103033048 slc7a10b,slc7a10,LOC108428368,LOC108274532,LOC107679961,LOC107752484,LOC105900738,LOC107555706 coding downstream 249287 20881830 ~ 20895098 (+)
ccdc34 NA coding downstream 280238 20912781 ~ 20915900 (+)
LOC103034349 LOC108428426,LOC108274949 coding downstream 284963 20917506 ~ 20923676 (+)
ccdc77 ccdc77,LOC107754361 coding downstream 295747 20928290 ~ 20936087 (+)
LOC111193104 NA non-coding upstream 1783 20284677 ~ 20288047 (+)
G75131 NA non-coding upstream 167090 20060370 ~ 20122740 (+)
G75034 NA non-coding upstream 484854 19804766 ~ 19804976 (+)
G75033 NA non-coding upstream 490181 19799385 ~ 19799649 (+)
G75026 NA non-coding upstream 524065 19761774 ~ 19765765 (+)
G75300 NA non-coding downstream 207990 20840533 ~ 20840981 (+)
G75309 LOC108428429,LOC108275416,LOC107566260,LOC107682256 non-coding downstream 237167 20869710 ~ 20873881 (+)
G75313 NA non-coding downstream 254612 20887155 ~ 20910244 (+)
G75310 NA non-coding downstream 306808 20939351 ~ 20941050 (+)
G75323 ankrd26,LOC108428422,LOC105913370 non-coding downstream 313070 20945613 ~ 20947024 (+)
LOC103028745 NA other upstream 81875 20203619 ~ 20207955 (+)
LOC103044129 NA other upstream 752213 19527212 ~ 19537617 (+)
tmem17 tmem17,znf774,LOC107678976,LOC107753710 other upstream 827643 19459958 ~ 19462187 (+)
cadps2 NA other upstream 967055 19140149 ~ 19322775 (+)
G74832 NA other upstream 1204274 19082816 ~ 19085556 (+)
G75383 morc2,LOC107754332,LOC107701074,LOC107674835 other downstream 390713 21023256 ~ 21025128 (+)
G75391 pus7 other downstream 456079 21088622 ~ 21096906 (+)
mov10l1 NA other downstream 617924 21250467 ~ 21264776 (+)
LOC103028957 rfx7,LOC108428391,LOC108275305,LOC107695007,LOC107563886,LOC100538179,LOC107741823,LOC100694937 other downstream 2122430 22754973 ~ 22780959 (+)
LOC103047784 LOC108428360,LOC108274708 other downstream 2149192 22781735 ~ 22815522 (+)

Expression


Co-expression Network