irak4 (irak4)



Basic Information


Item Value
gene id irak4
gene name irak4
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 21578912 ~ 21591254 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007244321.3
AACACCATCGATATCTCACTTTAAAAGTTACCTACATGGTGACGCTCATAAACCCGAGCAGCCAGTCTGCAGTGCTGTGACTGAGCGGAGGAGCTGGAGATACATTAGAAATGTGTCAGAGATAAAGGACTGCTGAAGCTCTGTCTCCTGAGctgagtgaggagagagagcgagctgGTTTCCGTGTTGAAGAGGTTCAGATGTAGCTAAAGGGGAAATGACTTCAAACTGAGGAAGTGTCTCAATATGGGAAAaacccacactcacacacttaaacacacacacactctgatatCATAAACTCGCTCCTcggtgaatgtgtgtgtggctttaGTCCGCGTATTGTTAAAGAAGCTGGTTTTAATTAGAGGTTGAGGGAGTCCTGAGGTCCAGTATGAGCAGCAGCGCTGTAACAGCTGATACCTTCATCAGGAAGCTCAGTCGCTCCACTCTCAGGACCCTCTCAGACTTCCTGGACCCTCAGGACGCGTGGAGAACTGTTCTGATGGACATACAGAAACCGACAGGAGAACCTAGATACACTCAGCTGCACCTCAGGAGGTTTGAAAGGCTGTTGGCTCAGGGTAAAAGTCCCACAGTAGAGCTGTTGTATGACTGGGGGACCACAAACAGCACAGTTGGAGAACTGGTTGATATTCTTGTCAGAAACAAGCTGTTTGCTCCTGCTAGAGTCCTTCTGCCAGATATAGCTGCAACACCTGCTCCAACACCTGTCACAAATCAGAGGGCAGAGAGAGATCCTCCCATTCAGTACCACCGGGAGGAGACTAAGCTCCTCAGACTCGCAGCAGAAGAAGCACATCACACCCCACCTGACAGCACCACACAACCAGAGGAGAACCAGGAGCCTGATGAAGAAGGATTCTACACTTTTACATATCAAGAGCTGACGGTGATCACAGAAAGCTGGGATGAAAGGCCAGTTTCGGATGGAGGCAGGAGACTCGGGGAGGGAGGCTTTGGAGTTGTGTTCAAAGGCATCCTCAGCACCACACCTGTAGCAGTGAAGAAACTCAATTTAGAAgatgaattagagctgaaagcTCAGTTCAAACAAGAGATTCAGACACTGAAGAGGTTAAAACATGTAAATCTGGTGAATATGGTGGGTTATTCCAGTGACGGCCAGCACCCATGTTTAGTCTATGCTTACATGTCAAATGGTTCATTGCTGGATCGACTAGCATGTGAGGGGGGAAGTGATCCTCTCTTCTGGAAGTTGAGGTGTTCAATAGCATTGGGCACAGCAAGAGGACTGGAATACCTTCACCAACACAACCACATACATCGAGATGTGAAAAGTggcaatattttgttggacGATTCCTTCGTTTCGAAGATTTCAGATTTTGGGTTAACCCGAGCCTCAGCTAAACATTCCTGCACAACAGTAATTACAGAGAGGATTGTGGGTACGACAGCTTACATGGCACCTGAGGCACTGCGAGGAGAGATCACTCCCAAATCAGATGTGTTCAGCTTTGGAGTGGTGCTGCTGGAAATATTATCTGGACTTCCGCCAGTTGATGAAAACCGGGACCCAAAGCTTCTGATAGATATGAAGGATGAAATTGAGGATGAAGAGATCATGCTGCAGGAGTTTGTAGATAAGAAAATGGAAGACTGGGACATGGAGTCTATAGAGAAGATGTACGGGGTGGCAAGTCAGTGCCTAAATGAAAGGAAGAACAGGAGGCCTCTGCTGAAGGAGGTGACTGCTGAGCTGGAGGATCTCTCTCATTGAGACCTGATGAGCTAAACTAAGACAAACATTTGTAAAAATGAATGCTTGAAtagattttaaatgtaaacttttaatactgtaaatatttatgtatattaaaatagcttatatCTGTAGTAAAATTCTGCAACATATTAAAGAATTTTATAGCAA

Function


symbol description
irak4 Predicted to enable ATP binding activity; magnesium ion binding activity; and protein serine/threonine kinase activity. Acts upstream of or within positive regulation of transcription, DNA-templated and response to bacterium. Predicted to be located in cytoplasm. Is expressed in brain; gill; heart; immune system; and liver. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human IRAK4 (interleukin 1 receptor associated kinase 4).

NR:

description
PREDICTED: interleukin-1 receptor-associated kinase 4 isoform X2

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process
GO:0007165 signal transduction biological_process
GO:0005524 ATP binding molecular_function
GO:0004674 protein serine/threonine kinase activity molecular_function
GO:0000287 magnesium ion binding molecular_function

KEGG:

id description
K04733 IRAK4; interleukin-1 receptor-associated kinase 4

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007244321.3 True 1918 mRNA 0.46 11 21578912 21591254

Neighbor


gene id symbol gene type direction distance location
tmem117 tmem117 coding downstream 19420 21475745 ~ 21559492 (-)
LOC103045028 NA coding downstream 279230 21293359 ~ 21299682 (-)
pclaf kiaa0101 coding downstream 340718 21236632 ~ 21238194 (-)
LOC103043194 csnk1g1,LOC108415052,LOC108274686,LOC106573333,LOC107738908,LOC107559435 coding downstream 343794 21199250 ~ 21235118 (-)
LOC103042467 rps17,rs17,LOC103042467,LOC107389132,LOC108428414 coding downstream 381393 21190045 ~ 21197519 (-)
LOC103022647 NA coding upstream 321270 21912524 ~ 21946943 (-)
pdzrn4 pdzrn4 coding upstream 459984 22051238 ~ 22145393 (-)
cntn1 cntn1,LOC108275444 coding upstream 698819 22290073 ~ 22421277 (-)
LOC103026605 NA coding upstream 1000366 22591620 ~ 22627981 (-)
LOC103026897 LOC103026897,LOC108428397 coding upstream 1038933 22630187 ~ 22637125 (-)
G75542 twf1,LOC108428409 non-coding downstream 3257 21566322 ~ 21575655 (-)
G75451 NA non-coding downstream 333382 21245264 ~ 21245530 (-)
G75447 NA non-coding downstream 391167 21184875 ~ 21187745 (-)
G75444 LOC108428417 non-coding downstream 403844 21172622 ~ 21175068 (-)
G75424 NA non-coding downstream 513765 21064348 ~ 21065147 (-)
G75554 NA non-coding upstream 34815 21626069 ~ 21626282 (-)
LOC111193107 NA non-coding upstream 130391 21721645 ~ 21724907 (-)
G75584 NA non-coding upstream 219286 21810540 ~ 21810761 (-)
G75611 NA non-coding upstream 350316 21941570 ~ 22001415 (-)
G75618 NA non-coding upstream 377451 21968705 ~ 21971088 (-)
LOC111193105 LOC102794092,LOC108274651,LOC107571202,LOC108428364 other downstream 305895 21269504 ~ 21273017 (-)
gatd1 pddc1,LOC102788149 other downstream 507666 21065319 ~ 21071246 (-)
LOC103032014 maf,LOC108428434,LOC108274756,LOC102790406,LOC102298902,LOC101477682,LOC102192535,LOC101173775,LOC100702616,LOC107663990,LOC107565340 other downstream 830704 20622641 ~ 20748208 (-)
hsd17b12 hsd17b12,hsd17b12a,LOC107661451,LOC107696265,LOC107573907,LOC107716735,LOC107753600 other downstream 1478662 20084428 ~ 20100250 (-)
G75207 api5,LOC107696269,LOC107753602 other downstream 1546885 20027162 ~ 20032027 (-)
LOC103024007 LOC108428399 other upstream 851482 22442736 ~ 22574013 (-)
LOC103033738 LOC103033738,LOC108444230,LOC106560753,LOC105008418,LOC108274439,LOC107549618,LOC107686877 other upstream 1733323 23324577 ~ 23366216 (-)
LOC103042310 ucmab,ucma,LOC107720768,LOC107569716,LOC107673257,LOC108275358,LOC107559968 other upstream 2235960 23827214 ~ 23833068 (-)
deaf1 deaf1,LOC107726848 other upstream 2649644 24240898 ~ 24260530 (-)
LOC103025724 tmem80 other upstream 3199938 24791192 ~ 24798616 (-)

Expression



Co-expression Network