LOC103044821 (anxa2,LOC108433632,LOC107739086,LOC107724175,LOC107659511,LOC107550215)



Basic Information


Item Value
gene id LOC103044821
gene name anxa2,LOC108433632,LOC107739086,LOC107724175,LOC107659511,LOC107550215
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 16958574 ~ 16965560 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_007246492.3
GTGGAGGAGGCAGGACTAGAATGCTGCTGGGAGGGAATAAAGCTACTGGCAGTGGCCCTGGTATTtaaccaccacacccatctcaCAACTCATAGCTGGGACTCTGCTGTGCATCATTCTTACGCTGCTCACAAAGAAGGTCAAAGATGGCTCTGGTAGCTGAATTCCTAGGTCAAATCACATTTAACCTTGGGgaCAACGAGCCCACCTACCCCACTGTGGTTCCTGCACCCGACTTTGATCCTGACAAAGATGCTGCCAGAATTGAGACCGCTATCAAAACCAAAGgtgTGGATGAACAGACTATTATTCAGGTCCTCACCAAACGGACGTATGCCCAAAGGCGGGAAATTGCCTTTGCATATGAGAGAAGAGCCAAGAAGGATATGATTTCTGCCCTCAAATCGGCACTGTCTGGCTCACTGGAGACAGTCATTCTGGGTCTGATGAAAAGCACTGCTCAGTATGATGCCTCTGAGATCAAAGCCTCTATTAAGGGTTTGGGGACAGATGAGGAGAGCCTGATTGAGATCGTCTGCTCTCGGAGCAATGCTGAACTGATGGAGATAAAGAAAGTCTACAGAGAACTGTTCAAGAAGGAATTGGAAAAGGATGTGGCTGGAGACACATCAGGAGACTTTGCTAAACTGCTGCTGGCTCTAGTGGAGGCCAAGAGGGCTGAGCCCAGCAGTGTAGTTGACTATGAGAAGATTGATGAAGATGCCAGAGCACTGTATGAAGCTGGAGTGAAGAGGAAAGGCACAGATGTTAAAACCTGGATCTCAATCATGACAGAGAGGAGTGTCCCTCATCTGCAGAAAGTGTTCGACAGATACAAGAGCTACAGCCCGTATGACATGCAGGAGAGCATCAGGAAGGAAGTGAAAGGAGATCTGGAGAAGTCTTTTCTTACATTGGTCCAGTGCTTTGAAAACAAACAACTCTACTTCGCCAACAGACTCAGTGAGGCCATGAAGagtaAAGGAGCGAAGGAGAAGGTGGTGACCAGGATCATGGTGTCTCGCTGTGAGGTGGACCTGAAGAAGATCAGGTCTGAGTTCAAGGCCCAGTTTGGGAAGTCTCTGTACCAGACCATCTTTGAGCACACTAAAGGAGACTACCAGGCGGCTCTGCTGAGTCTGTGTGGTGGAGATGACTGAAGTGGACCGTAAGTCATGAAGGCCACGCCTCTGATCTGTCATAAATAAACTGGACTCACAAAAAGGATTGTATAATGTCCTGTCAAGATATCCTGTAGATAATACATCTCAACGTGCCAATATAACATGTTTGAAGTATTGACTTTTGAATTTGAGTGGTCAGACCTATGTCATTAAGCTTATATGAATTTTGGGACCAGTTTTAATGCACATATCTaaatttttactttatatacaatGTTTTGCTACATTATTCTcatctttatcatcatcatcagcagctgCTGCTTCATCTACAGCAGATCTAGAAGGAGTGCAGCATCTGTAatagtccagcagagagcagtaGAGCACCACATGACTTTGTTTCTTCTTATTCTGTTTTAATTAGACTCAAGAATCGCTCTGCTTGCTGCTAAGGCTTTACTTCACTTTTTCCCCACTTTGCTTTGATGtttacagcctttttttttttttaataaatagtgtGAAAATATTTGATCTCAAATACGATTTGCATATTTTATCCCCTCATTTCGAAAAGGAATAAGAgcaaaaaagttttcttttttttttcagaaatgagAAAACGTTTTCTTACTGCGCTCAtgatgaaatataaatatgcactGCTTCCATGTACAGCCAAATAAAGGCTTTGATTAGAGAGA

Function


symbol description
anxa2 Enables several functions, including S100 protein binding activity; enzyme inhibitor activity; and phospholipid binding activity. Involved in several processes, including negative regulation of low-density lipoprotein particle receptor catabolic process; positive regulation of cellular component organization; and positive regulation of low-density lipoprotein particle clearance. Located in several cellular components, including bounding membrane of organelle; extracellular exosome; and lipid droplet. Part of AnxA2-p11 complex and PCSK9-AnxA2 complex. Colocalizes with membrane raft. Implicated in osteonecrosis. Biomarker of cholangiocarcinoma; invasive ductal carcinoma; pancreatic ductal carcinoma; and paranasal sinus benign neoplasm.

NR:

description
PREDICTED: annexin A2-like

GO:

id name namespace
GO:0005509 calcium ion binding molecular_function
GO:0005544 calcium-dependent phospholipid binding molecular_function
GO:0004859 phospholipase inhibitor activity molecular_function
GO:0008092 cytoskeletal protein binding molecular_function

KEGG:

id description
K17092 ANXA2; annexin A2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_007246492.3 True 1831 mRNA 0.44 13 16958574 16965560

Neighbor


gene id symbol gene type direction distance location
bnip2 bnip2,LOC107703138 coding downstream 128593 16814916 ~ 16829981 (-)
otud7a otud7a,si:dkey-37f18.2,LOC107715690,LOC107752330,LOC107659507,LOC107550219,LOC107698115,LOC107598848,LOC108275340 coding downstream 219909 16618151 ~ 16738665 (-)
LOC103042575 LOC108433637 coding downstream 430487 16489647 ~ 16528087 (-)
acsbg1 NA coding downstream 500820 16447496 ~ 16457754 (-)
cib2 cib2,LOC103027299,LOC107573330,LOC107752320,LOC101476243 coding downstream 544229 16384549 ~ 16414345 (-)
ice2 NA coding upstream 1222 16966782 ~ 16988490 (-)
LOC103045127 rora,roraa,LOC108433630,LOC106561150,LOC106573506,LOC103141220 coding upstream 27351 16992911 ~ 17425461 (-)
LOC103045440 zgc:162595,LOC108433606,LOC108275248 coding upstream 622468 17588028 ~ 17600473 (-)
etfa etfa,LOC107712526,LOC107557988 coding upstream 996135 17961695 ~ 17975485 (-)
scaper scaper,LOC107712524,LOC107662441 coding upstream 1024927 17990487 ~ 18110831 (-)
G74368 NA non-coding downstream 157523 16797045 ~ 16801051 (-)
G74306 NA non-coding downstream 172535 16770442 ~ 16786039 (-)
G74295 NA non-coding downstream 211052 16743060 ~ 16747522 (-)
G74286 NA non-coding downstream 268217 16659503 ~ 16690357 (-)
G74285 NA non-coding downstream 316918 16640842 ~ 16641656 (-)
G74407 NA non-coding upstream 289357 17254917 ~ 17255289 (-)
G74447 NA non-coding upstream 839775 17805335 ~ 17813965 (-)
G74556 tpm1,LOC108441842 non-coding upstream 879566 17845126 ~ 17866138 (-)
G74599 slc27a2,LOC108414297 non-coding upstream 1252729 18218289 ~ 18227676 (-)
G74640 NA non-coding upstream 1385071 18350631 ~ 18350936 (-)
LOC103041134 rps27l,zgc:136826,LOC107752326,LOC107598918,LOC101156845 other downstream 488251 16467089 ~ 16470323 (-)
LOC103046265 pkp3 other downstream 1177896 15758303 ~ 15780678 (-)
LOC103040324 NA other downstream 1543961 15381329 ~ 15414613 (-)
LOC103037068 cpne8,LOC108274474,LOC107679956,LOC107752477,LOC107723993,LOC105026415,LOC106561599,LOC105028206 other downstream 1744290 15123814 ~ 15214284 (-)
hbp1 hbp1,LOC107732286,LOC107701066 other downstream 2161291 14709058 ~ 14797283 (-)
nrg4 NA other upstream 911466 17877026 ~ 17885395 (-)
G74591 isl2,LOC105022634 other upstream 1017187 17982747 ~ 18029747 (-)
G74791 NA other upstream 1973614 18939174 ~ 18940464 (-)
LOC103034453 LOC108436916,LOC107753633,LOC107659484,LOC107573489,LOC107752304,LOC108181664,LOC107598834 other upstream 2027108 18992668 ~ 19008366 (-)
G74838 wasl,LOC105896696,LOC108275301 other upstream 2105378 19070938 ~ 19072888 (-)

Expression



Co-expression Network