isl2 (isl2,isl2a,LOC107589357,LOC107662481,LOC107712508,LOC107688926)


Basic Information

Item Value
gene id isl2
gene name isl2,isl2a,LOC107589357,LOC107662481,LOC107712508,LOC107688926
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 17979428 ~ 17986224 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007246513.3
CGCATCGGCTCCAGGTTCTCAGTGAGCTCGGCACGGTGCACACACCTACATAcacacccctcacacacacactcacacatatacatatacacacatacacgcgCGCGTAcgcgcacacagacacacagctacacacacatacacacggaCTCTCCCGCTGTTCTTCGTCCTGCGCAGCCCTGGGCGCTCTGGCCATCCTGTATGGTGGATATTCTGCTCCACTCTTCTTTCTTGGGTGATATGGGGGATCATTCCAAAAAGAAGTCCGGAATCGCCATGTGTGTGGGCTGTGGAAGTCAGATCCATGaccagtacatcctgagagtgTCCCCGGACCTGGAGTGGCACGCGGCCTGCTTGAAGTGCGCCGAGTGCAGCCAGTACCTGGACGAGACCTGCACGTGCTTCGTCCGAGACGGCAAGACCTACTGCAAGCGAGATTACGTACGGTTATTCGGGATTAAATGTGCCAAGTGTAACAGCGGGTTCTGCAGCAGCGAGCTGGTGATGAGGGCTCGGGATAATGTCTACCACATGGAGTGTTTCAGGTGCTCGGTATGTAGCAGGCACCTTTTGCCCGGAGATGAGTTCTCTCTGCGGGAAGAGGAGCTGCTCTGCCGGGCTGACCACGGGCTGCTGCTAGAGAGAGGAGCGGCGGGAAGCCCCCTCAGTCCGGCAAACATCCACTCAGCCAGAGCCCTCCACATGCCAGAGCCCGTGCCGGTGCGGCAGCCTCCTCACCGGAACCACGTCCACAAGCAGTCGGAGAAAACCACCCGCGTGCGCACCGTTCTCAACGAGAAGCAGCTGCACACGCTGCGGACGTGCTACAACGCGAACCCGCGGCCGGACGCGCTGATGAAGGAGCAGCTGGTTGAGATGACGGGCTTGAGTCCGCGAGTCATTCGGGTGTGGTTCCAGAACAAGCGCTGCAAGGACAAGAAGAGGTCCATTCTCATgaagcagctccagcagcagcagcacagcgaCAAAACGAATCTTCAAGGACTGACAGGAACGCCATTAGTTGCTGGCAGTCCAATCAGACACGACAACACGGTGCAGGGTAATCCTGTAGAGGTGCAGACCTACCAGCCCCCCTGGAAAGCTTTGAGTGAATTCGCCCTGCAGAGTGACCTGGAGCAGCCCGCCTTCCAGCAGCTGGTATCCTTTTCTGAGTCGGGCTCTCTGGGGAACTCCTCGGCCAGTGATGTGACCTCTCTGTCGTCGCAGTTGCCGGACACCCCCACCAGCATGGTGGCCAGCCCGGTGGAAACGTGAACTCCGCGCGAGCCGCACGGCCGCGCACCCGCCTGTCCCAGCATGCACCGCGCGAGAACCCCCTGCATGAGCCCCAAGCGGATCGAGGGATTACAACACACACGCATACGAACACGCACACATACCCACAGACACTCGTACACACTGCAACTGTGGATCTAAAGCTGAAAACACGGAGCAAAGAAGCTCAATTTTCCACACCGTCGACCCACGTGGATCCAAAACAGACCAGAGCAGAACGGCCCGAGGAATATGAACAAGTTGAGCCACTGTCAACAagtttctattttcttttcttttttaataatgtcttaacagTATTCCCGCAGGGCTAACTGTGTTGCTCCATCACCCACGCCCCCTTGCCCTCAACCACCGAGACCAggacacacacctctctctgtCCTACTGCGCATGATCTCCGAAGACGATGTAGAAACAAAACTGCtatgtaaatgttttatcttGACGGATGGAGGACAGAATTGTTTGAACTTCtcgagaaaaaaagaaaaaacccgtaagttattgttatttattgttaGGACCTAACCGTCCGCGAGAATTACAAAATTAACTATGTTAATAAACTACGTTAAGTGTT

Function

symbol description
isl2a Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within blood vessel morphogenesis; exocrine pancreas development; and neuron differentiation. Predicted to be active in nucleus. Is expressed in several structures, including ectoderm; gut; liver and biliary system; nervous system; and neural tube. Orthologous to human ISL2 (ISL LIM homeobox 2).
isl2 Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in axonogenesis; neuron fate specification; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of neuron differentiation and neuron differentiation. Predicted to be part of chromatin. Predicted to be active in nucleus.

NR:

description
PREDICTED: insulin gene enhancer protein ISL-2

GO:

id name namespace
GO:0006355 regulation of transcription, DNA-templated biological_process
GO:0048665 neuron fate specification biological_process
GO:0048675 axon extension biological_process
GO:0005634 nucleus cellular_component
GO:0043565 sequence-specific DNA binding molecular_function
GO:0003700 DNA-binding transcription factor activity molecular_function
GO:0008270 zinc ion binding molecular_function

KEGG:

id description
K18492 ISL2; insulin gene enhancer protein ISL-2

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007246513.3 True 1885 mRNA 0.55 6 17979428 17986224

Neighbor

gene id symbol gene type direction distance location
tmem266 tmem266,LOC107557978 coding upstream 17767 17887308 ~ 17961661 (+)
lactb lactb,LOC107712527,LOC107659517,LOC107589333,LOC107557987 coding upstream 103189 17868563 ~ 17876239 (+)
tpm1 tpm1,LOC107712528,LOC107659515,LOC107739081,LOC103141214,LOC103379363,LOC103149890,LOC108237348,LOC103040917,LOC108441842,LOC107589334 coding upstream 113300 17845101 ~ 17866128 (+)
LOC103025470 tln2,LOC108433629,LOC107659514,LOC107703225,LOC107739102 coding upstream 172528 17684670 ~ 17806900 (+)
foxb1 foxb1 coding upstream 1081497 16895315 ~ 16897931 (+)
atp8b4 atp8b4 coding downstream 154789 18141013 ~ 18177415 (+)
cops2 cops2,LOC107557994,LOC107589327 coding downstream 203787 18190011 ~ 18195649 (+)
cep152 NA coding downstream 209926 18196150 ~ 18211686 (+)
LOC103027907 slc27a2,LOC108414297 coding downstream 227885 18214109 ~ 18227746 (+)
LOC103028223 duoxa2,LOC103028223 coding downstream 440640 18426864 ~ 18430628 (+)
G74461 NA non-coding upstream 14653 17961696 ~ 17964775 (+)
G74413 NA non-coding upstream 502448 17476757 ~ 17476980 (+)
G74335 rora,LOC108433630,LOC106561150,LOC107659510,LOC107598851 non-coding upstream 970889 16989028 ~ 17008539 (+)
G74339 anxa2,anxa2a,LOC108433632,LOC107739086,LOC107724175,LOC107659511,LOC107550215,LOC107598852 non-coding upstream 1015046 16957657 ~ 16964382 (+)
LOC111193101 NA non-coding upstream 1092280 16831109 ~ 16887148 (+)
G74471 scaper non-coding downstream 8370 17994594 ~ 17995133 (+)
G74477 NA non-coding downstream 129359 18115583 ~ 18182105 (+)
G74494 ctdspl2a,LOC108411888,LOC108275364,LOC107557990,LOC107739078,LOC107662443,LOC107589331 non-coding downstream 134385 18120609 ~ 18123835 (+)
G74479 NA non-coding downstream 191471 18177695 ~ 18179770 (+)
G74510 NA non-coding downstream 225688 18211912 ~ 18213361 (+)
G74169 NA other upstream 1691099 16286676 ~ 16288329 (+)
svip svip other upstream 2401895 15572302 ~ 15577533 (+)
rpgrip1l rpgrip1l other upstream 3058425 14891534 ~ 14921003 (+)
G73533 NA other upstream 3329877 14648829 ~ 14649551 (+)
LOC103043719 NA other upstream 5081497 12871484 ~ 12897931 (+)
G74649 NA other downstream 468627 18454851 ~ 18455197 (+)
LOC103029914 scamp5,scamp5a,LOC108436905,LOC103363822,LOC107395508,LOC107703195 other downstream 484480 18470704 ~ 18479345 (+)
G74832 NA other downstream 1096592 19082816 ~ 19085556 (+)
cadps2 NA other downstream 1153925 19140149 ~ 19322775 (+)
tmem17 tmem17,znf774,LOC107678976,LOC107753710 other downstream 1473734 19459958 ~ 19462187 (+)

Expression


Co-expression Network