LOC103030119 (hcn4,LOC108436942,LOC107696280,LOC107573709,LOC106530001)



Basic Information


Item Value
gene id LOC103030119
gene name hcn4,LOC108436942,LOC107696280,LOC107573709,LOC106530001
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 19692184 ~ 19725549 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_015605106.2
GGCACCGCGCGCGcgctccgtctctctctcctctctctctcctcttcactcattcactccgCCACGCAACGCTGCGGGACGCTGCTGGATTACGCTCTTCGtgtggctggctggctggctggctggctcgTTTGCATCACCCAAGATCACCGTTTTTGTTTTGGAGTGTGTTTTTTTGAGGGGAGGCTCGTGCGTCGTCACGTCGTTTACCTAACCTCTGTctatcaatccatcatccatccacctaTCCATCCGTCCTCCTTCAGCAGCATCCCTGCATCCCAGCGCGCTCTGCATCTCAGCACGCTCGCCTggcttgtctctctctttctctctctctctctctccctcactctctctccctctctctctctcactggcgGGATGGACGGCACGCGCTGCTCTCCAGCTTCTCTGCGCGATGCCCATGTCATCTGAGGCTTAAGAAGAGGACAAGAAACAAAGCAActtatctctccctctccacTGTTCTCTTTTACCCTCCATTCAGCTTGCATCTCTTTTGTTGCCATGGACCGGCTGCACTCATCCATGCGCAAGCGTCTCTACAGCCAAGGGGACACGGCGGAGGATGGTGAGCAGGATGCGCGCAGGAAGAGCGTGAGGATGAAGCAGCTGTTGCCCTCTGCCTCGCCGACCGGGAGcagcggagagagagaaagagcaggaggtgaacgaggaggaggaggaggtgggggatcaggaggaggaggaagcggGGGAGGCGAGACGGAGACGGACAtgggcagcagagccttcaTCAGGGCAAACGGTGACTGCCGGAGGTTCAGGGGCAGCAGCAGCATGCCAGAGGGAGATGCTGCCGAGCAGAGGCGCCTGATCACCGAGGAGGAGGCCAGCCctgaggaggaggacgaggaggaggaggatgaggaggcaGAGGAGAAGTGGAGgaagagggagcgagagaggaagagggagatggaggaagaggaggtggtggtggaggagagggagagggagaggacaCCCAGTCTGGGCAAGTTGGAGAGTGGCGAGCAGATGGACGAGGAGAGGCTGTACCAGGCCGGTTTCATGCACAGGCAACTGGGCGCCATGCTGCAGCCCGGGGTCAACAAGTTCTCCCTGCGCATGTTCGGCAGCGAGAAGGCCGTGGAGAGGGAGCAGGAGAGGGTCAAGTCGGCCGGCTTCTGGATCATCCACCCCTACAGTGACTTCAGATTCTACTGGGACCTTATCATGCTGCTATTGATGGTGGGAAATCTGATCATCATCCCTGTGGGAATCACATTCTTCAAGGATGAGCACACCCCGGCCTGGATCGTCTTTAACGTGGTCTCCGACACCTTCTTCCTAGTGGACCTGGTCCTGAACTTCCGGACGGGAATCGTGAAGGAGGACAGTACGGAGATCATTCTGGACCCTCAGCTGATCAAGGTGAGGTACTTGCGCAGCTGGTTTGCTGTGGACTTCATCTCCTCCATCCCTGTGGATTATATCTTCCTCATTGTTGAGACTCGGATTGACTCGGACTTCTACAAGACCGCCAGAGCTCTGAGGATCGTCCGCTTTACCAAAATCCTCAGTCTTCTCAGACTGCTACGACTGTCCCGCCTCATCAGATACATTCACCAGTGGGAGGAGATTTTCCACATGACCTACGACCTGGCCAGCGCTATGGTGCGTATAGTGAACCTGATTGGCATGATGCTATTGCTGTGCCACTGGGACGGCTGCCTGCAGTTCCTCGTGCCCATGCTGCAGGATTTCCCCTCCGACTGCTGGGTTTCTAAAAACAAAATGGTGAATGATACTTGGGGTCAGCAGTACTCTTATGCCCTGTTTAAGGCTATGAGCCACATGCTGTGTATTGGCTATGGCATGTACCCACCCGTAGGCATGACAGACGTTTGGCTGACCATCCTCAGCATGATCGTAGGTGCCACCTGCTACGCCATGTTTGTGGGTCATGCCACCGCCCTCATTCAATCACTGGACTCCTCACGAAGGCAATACCAGGAGAAGTACAAACAGGTAGAGCAGTACATGTCCTTCCACAAGCTTCCTGCAGACATGCGCCAAAGGATCCATGACTACTACGAGCACCGTTACCAGGGCAAGATGTTTGACGAGGAGAGCATTCTAGGAGAACTGAATGAGCCACTCAGAGAGGAGATCATCAGTTTCAACTGTCGAAAGTTGGTGGCCACCATGCCCTTATTTGCCAATGCAGATCCCAACTTTGTGACCTCCATGCTAACAAAGTTACGCTTTGAAGTCTTCCAGCCAGGGGACTACATCATTCGAGAAGGCACTGTAGGAAAGAAGATGTATTTCATCCAGCATGGGGTGCTAACAGTCCTGACCAAGGGCAGCAAAGAGACAAAGATTTCAGACGGATCTTATTTTGGAGAGATCTGTTTGCTGACCCGGGGCAGGAGAACAGCCAGCGTGAGGGCAGAAACCTACTGCCGCTTGTACTCCCTGTCTGTGGATCATTTTAACGAAGTGCTGGAAGAGTACCCGATGATGCGGCGAGCCTTTGAGACAGTAGCCCTCGACCGCCTTGACCGCATTGgAAAAAGAAACTCTGTTCTCCAGCACAAGGTACAGCGGGATCTCAACTCAGGTGTGCTTAACTACCAGGAAAATGAGATCATCCAGCAGATTGTGCAGCATGACAGGGACATGGCTCACTGTGCCCACCTATTGCAgactcctcctccagctccacaTATAGCACACAATCCTTCCTCACACACCCCAGTCATCTGGGCTCCTCTCATCCAGGCGCCTCTCCAAGCTGCTGCTGCCACCACCTCTGTGGCCATCGCCCTTACTCGACACCCGCATCTACCCCACACGCTCTTCCGGCCTCCAGTGCCCTTGCTAGGTTCACTCAAAGACCCGCCAGGCCATTTGAGAAGGTTCCCCATGCCAACTGCAGCTACAGGTGCTTCCACACGGGGTGGCTCATCTTCTGGTGCCAGTTCTCAGCTTGGCTCAGGTGTGGAAACACCTATTCTAGATTCTCTCCTAGCCAAAAGTTCTGCAACAGCATCCACACCTCCTCCAATTTCTGCTTCCAGCTCCCTGCCATCTTCAACCACAACCACAATTACCACCTCCACATCAAGCATCAGCGAAGCATCCGTCTTCTCCCACAGGCCTCTGGCCACCTGTGGTTCTCGAACCTCAAGTATAGCCCAGCTTCACACCCAACCTCAGTTTCCACCAGCTTCTTTTCCCAACATCACTGCTCCACTGCCTGGCTTCTTTCAACAGGGGGCACTAGGTGGAGATGCAGCTCAGTTTTCCATCCCCCCTGCCTCTACTCTAACCCCTTTGATAGCCCACTCAATTAGCCCAATATTGACCCAACTGCAGTCCACGCAACCCAGTCTTCAGCAGGCCAAACGCAGTCAGGAGGTAAGCAAGCCAGTCAGAACAGCCACTCCATCACCATCTACCAGATCTCCACTTTGCTCCACGAATCTTTCAGAGCAGTCTTCCCCAAAACCCCAGACTCAGGACCCTCAAAACATACTACAGCCTGATATTCTCCCCCATCAGCCCTGTGAACCCTCTGCCCTGGCCTCGCTTGCCCAGTATGGGTCAGGGAATGCCTCCCCATGTAGTACCCCACCAGCCTGGAGCCCCATGTCCCAGAGTCCCTTGGTTCAACGGAAGAGAACACCCCTTCACAGCAACCCTTCCAGCACTTCCGGGTCTCAGAGTTCCCTTCTGTCCCCTCAGACCCTCTTTCCTCCTCCACCCTCCCAGCCGCGAGAGAGGGGCGGGTCACTGGTTGATCTCCCCTCTCAGGACGTCAGCAccatctctatatctctcccCTCGCCTCATACTCTTGAAAGACCCCAGCCAGTAAGGAAAGTCTCCCATGTCCCAGATCCGTCCCATGTGGTGTCTACTTCAGGTTTCGCCAAAACCCCCTCACCCACCCCTGTAACTAAACCATACAGTTCAATACCAGGACATGTGGCCCTATCGAGACAGACTTCAAAAGGGTCCATAGTGCAGACTGGCTCTTCTAGTGGTTCACCAGCCCCTGGGTCTAGAGACAGATCCAGTCCAGGGACGCCAAGCTTACAACCCAAACTCCCATCAAACTTATGAGACCAGACTGTACCCTTGTCTATTGTACAGACTGTGTTTTTTATCACCTAGTAATATCTATCTACAAAAAAGAAACTTTTATGGCTGAGAAGAGGACGTTTGTCTACCTGCATTTATAATCGTACAATGACTACTTTTCAACTCATGCCAAATGAAGGAATATGGAAGTGACTGATGACTGAATGAGCGTGTATGGGAATGATTGAGTTGTGTACAAGCAAAATGACTGTGTCTTCCAagttcttttagcattttttgcAATACTAATGTCTGACAGTGAGATTATGTAGGGATATGCAACAAATAGcagtttccaaaaaaaaaaagaagtcttTACAGTAATAACAGAATTATGGTTGTCGTTGTACCAATAAAAAATGGCCCCTTTCAAAGGAGTGAAATATCCTGGGGAAAGATGCAAAAATACTCCTTGCTCTTCACCATATCATCTAGTGtggtagaaaaaaaaaccaTGTAGTACAGATCTCACTTATCAGgttgcacacacatacacacacacacacacacagaaatgcaTACACCTGATCCTCGTCATATTAATTATCAGACACAGACTGATTATTCCACTAGACCTTGCCCCCCAACCATACCTCCTTGTTGATCAAGGCGCACTGCTCAGTATTTATGGCCTTTCCTTTTTTAACAAAACTGCCTTAGAGCCTGAACGACCAGGGAACGATCCCCTCACTTCCACCACAAAAGAGATAAGATAAAGAATGTATGGCAATCATTTTGTATGTGCTTTCTATGTGTACTTGTGCGGTACCTAAGCAATAAAACTGTATGCTTGA

Function


symbol description
hcn4 Predicted to enable sodium channel activity and voltage-gated potassium channel activity. Acts upstream of or within heart contraction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Is expressed in heart primordium and pericardial region. Used to study sick sinus syndrome. Human ortholog(s) of this gene implicated in Brugada syndrome 8; Gilles de la Tourette syndrome; and sick sinus syndrome. Orthologous to human HCN4 (hyperpolarization activated cyclic nucleotide gated potassium channel 4).

NR:

description
PREDICTED: potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3-like

GO: NA

KEGG:

id description
K04957 HCN4; hyperpolarization activated cyclic nucleotide-gated potassium channel 4

RNA


RNA id representative length rna type GC content exon number start site end site
XM_015605106.2 True 4952 mRNA 0.52 8 19692184 19725549

Neighbor


gene id symbol gene type direction distance location
LOC103047267 parp6,parp6b,LOC108436940,LOC108275327,LOC107753615,LOC107661437 coding downstream 31922 19643325 ~ 19660262 (-)
LOC103046970 NA coding downstream 54532 19635125 ~ 19637652 (-)
LOC103046663 cox5aa,LOC103046663,LOC108436939,LOC107696286,LOC107716663,LOC107576348,LOC107678975 coding downstream 59745 19624687 ~ 19632439 (-)
LOC103045635 arid3b,LOC108436938,LOC108275332,LOC107575848,LOC107752332 coding downstream 69636 19596930 ~ 19622548 (-)
etfbkmt etfbkmt coding downstream 119648 19569330 ~ 19572536 (-)
LOC103021510 LOC108436943 coding upstream 4614 19730163 ~ 19749501 (-)
LOC103030439 ube2q2,LOC108436947,LOC107696278,LOC105015542,LOC107661444 coding upstream 37246 19762795 ~ 19772325 (-)
LOC103024527 fam19a5b,LOC103024527,LOC108428378,LOC107696241,LOC107753604,LOC107598818,LOC108274593 coding upstream 214086 19939635 ~ 19972658 (-)
ticrr NA coding upstream 311906 20037455 ~ 20051285 (-)
c8h11orf96 si:ch1073-281m9.1,cunh11orf96,LOC103025886,LOC107696240,LOC107661503,LOC107575890,LOC107580776 coding upstream 334837 20060386 ~ 20062075 (-)
G75069 NA non-coding downstream 4066 19640821 ~ 19688118 (-)
G74928 NA non-coding downstream 273380 19325392 ~ 19418804 (-)
G74911 aass,LOC102787118 non-coding downstream 337133 19354093 ~ 19355051 (-)
G74909 aass,LOC107753626,LOC107678990,LOC107752301,LOC107698474 non-coding downstream 342173 19344945 ~ 19350011 (-)
G74910 NA non-coding downstream 350248 19279652 ~ 19341936 (-)
G75081 NA non-coding upstream 20015 19745564 ~ 19746445 (-)
G75092 NA non-coding upstream 73836 19799385 ~ 19799625 (-)
G75093 NA non-coding upstream 79217 19804766 ~ 19804970 (-)
G75106 NA non-coding upstream 145593 19871142 ~ 19872681 (-)
G75208 api5,LOC107753602,LOC107661449 non-coding upstream 307061 20032610 ~ 20034759 (-)
G74838 wasl,LOC105896696,LOC108275301 other downstream 619296 19070938 ~ 19072888 (-)
LOC103034453 LOC108436916,LOC107753633,LOC107659484,LOC107573489,LOC107752304,LOC108181664,LOC107598834 other downstream 683818 18992668 ~ 19008366 (-)
G74791 NA other downstream 751720 18939174 ~ 18940464 (-)
G74591 isl2,LOC105022634 other downstream 1662437 17982747 ~ 18029747 (-)
nrg4 NA other downstream 1806789 17877026 ~ 17885395 (-)
G75100 LOC108436948,LOC108275266 other upstream 134145 19859694 ~ 19865982 (-)
G75207 api5,LOC107696269,LOC107753602 other upstream 301613 20027162 ~ 20032027 (-)
hsd17b12 hsd17b12,hsd17b12a,LOC107661451,LOC107696265,LOC107573907,LOC107716735,LOC107753600 other upstream 358879 20084428 ~ 20100250 (-)
LOC103032014 maf,LOC108428434,LOC108274756,LOC102790406,LOC102298902,LOC101477682,LOC102192535,LOC101173775,LOC100702616,LOC107663990,LOC107565340 other upstream 897092 20622641 ~ 20748208 (-)
gatd1 pddc1,LOC102788149 other upstream 1339770 21065319 ~ 21071246 (-)

Expression



Co-expression Network