LOC103033497 (grm8,grm8b,LOC107659486,LOC107698172,LOC107598887)


Basic Information

Item Value
gene id LOC103033497
gene name grm8,grm8b,LOC107659486,LOC107698172,LOC107598887
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035904.1
NCBI id CM008307.1
chromosome length 27092187
location 18672401 ~ 18838757 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022672241.1
AATCCCAAGACTCTATACTGTGTGCATGTTCGTAGTCCCAGGGGTCTGTGAATTCTGTAGTGAAGGTCACTCTTGCTAGGCCATTGATTGCCTAATATACCACTGCATTCTCAGACACAGCACTCCACTGACCTGAACTCACAGATGACCGACCTTATGTTTTCGAAACCGCAGAGAATGATCACTTTACCTTGGGACCTCCTCCCCCAGGGCAGGTGTACTGGTGATTCCATTCACTTTGTACGGCCCTTTCATACTGACCACATGCTGCAGTAACTGCACCACGACTGACAGACCGCCCACACTCCTGCTTGCTTGTCTTCTTATATACCTTAACCTTGCATTGTCATGGCGAGGAACTCGATGTGGCACAGCTGCCTTTTTATGCTGACAGTGGTGACCTGCTCCATCACCCAGCGCCCAGACCCCCTCACCCCCCCAACTCCTGAATACGCTCATTCCGTTAGACTAGATGGTGACATTATCCTGGGAGGCCTCTTCCCAGTCCATGCCCGAGGGGAGCGTGGTGCCCCCTGCGGTGAGCTGAAGAAGGAAAAAGGCATACATCGTTTAGAGGCCATGCTATTCGCCATTGACCTCATCAACAAGGACCCTGACCTGCTGCCCAACATCACACTGGGTGCTCGCATCCTGGACACCTGTTCACGGGACACCTATGCTCTGGAGCAGTCGCTCACCTTTGTGCAGGCACTTATTGAGCGTGACCCTTTAGATGTGCGCTGCGCTGGTGGAGAGCAACCCAGCTTTGCTAAGCCAGACAAGATTGTGGGTGTGATCGGTGCTTCCTCAAGTTCCGTCTCCATCATGGTGGCCAACATCCTGCGGCTGTTTAAGATCCCTCAGATTAGCTATGCATCCACTGCGCCGGAGCTGAGCGACAATACCCGATACGACTTCTTCTCCCGAGTGGTGCCACCTGACTCCTACCAGGCTCAGGCCATGCTGGACATCGTCACGGCCATGAGCTGGAACTACGTCTCCACACTGGCCTCCGAGGGGAACTATGGAGAAAGTGGCGTGGAGGCCTTTGTTCAGATCTCCCGGGAAACTGgtGGTGTATGTATTGCACAGTCTCTGAAAGTCCCTCGAGAACCCAGACCAGGAGAGTTTGACAAGATCATCTTGCGACTGCTGGAAACCCCTAATGCTCGTGCCATCATCATGTTCGCAAATGAGGACGACATCAGaCGCATCCTCAATGCAGCCAAGAGAAACAATCTAACAAATCATTTCCTCTGGGTGGGGTCGGACAGCTGGGGCTCGAAGATCCCCGTCGTTCAGCAGGAGAAAGTGGCCGAGGGGGCCATCACCATCCTGCCTAAAAGAGCTTCGGTTGATGCATTTGACAGATACTTCAAAAGCCGTTCCTTATCCAACAACCGGAGGAACGTGTGGTTTGCTGAGTTCTGGGAGGAGAACTTTGGATGCAAGCTGGGGATGCATGGCAAACGTCCTGGCAGCCCGAAGAAGTGTACAGGTTTGGAGAAAGTGGGAAGGGACTCCAGCTATGAGCAGGAGGGGAAGGTTCAGTTCGTGATGGATGCTGTGTATGCCATGGCTCATGCTCTTCACCGCATGCACAGAGACTTGTGCTCAGGATACCCGGGACTTTGCCCTCGAATGAGCACCATTGACGGCAAGGAGCTGCTAGGTTACATCCGAAATGTCAGTTTTAATGGAAGCGCCAAGACCCCTGTAACGTTCAATGAGAATGGAGATGCTCCTGGGCGATATGACATCTTCCAGTATCAGATTTCTAATGGATCAATAGCTGAGTACAGAGTCATCGGCCAGTGGACTGATCACCTTCATTTAAATATGGATGCACTTCAGTGGGTGAGCGGTGATTCATCCGTGCCCGCCTCGGTCTGCAGCCTGCCCTGCCGGACGGGCGAGCGGAAGAAGGTGGTGAAGGGAGTGCCCTGCTGTTGGCACTGCGAGCGCTGCGAGGGCTACCACTATCAGGCCAGCGAGTTCACCTGTCAGCTCTGTCCGTACGAGCAGCGCCCGGACCACAACCGCACCGGCTGCCAGCCCATCCCCATCATCAAGCTGGAGTGGCACTCCCCCTGGGCTGTGGTGCCCGTGTTTATTGCCATTCTGGGCATCATCGCCACTACTTTTGTGATAGCTACCTTCGTACGCTATAACGACACCCCGATCGTACGTGCCTCTGGCAGGGAGATGAGTTACGTGCTGTTGACTGGAATATTCCTCTGCTATATCATCACCTTTCCCATGATTGCAACCCCTGGAGTGTCTGTCTGCTCCTTCCGCAGGATCTTCCTAGGCCTCGGCATGTGCTTCAGCTATGCTGCCCTGCTCACAAAGACCAACCGCATCCACCGCATCTTTGAGCAGGGTAAGTGTTCGGTGGCTGCTCCCCGCTTCATCAGCCCAGCCTCGCAGCTGGTCATCACCTTCAGCCTGATCTCTGTGCAGCTGATGGGTGTACTGGTGTGGTTTATCGCTGACCCCCCACACACGATCGTGGATTACGGAGAGCAGCGCACGCAGGACCCTGAAAATGCCCGAGGAGTGCTCAAATGTGACATATCTGATCTCTCGCTCATCTGTTCACTGGGCTATAGTATTCTATTGATGGTAACATGCACTGTTTATGCCATCAAGACCAGAGGAGTACCAGAGACCTTCAACGAGGCCAAGCCTATTGGATTTACTATGTACACCACCTGCATCATATGGCTTGCCTTCATACCCATTTTCTTTGGGACAGCACAGTCTGCAGAGCGGATGTACATCCAGACGACCACCCTGACCGTGTCTTTGAGCCTGAGTGCGTCGGTATCTCTGGGGATGCTCTACATGCCCAAAGTCTATATAATCATCTTCCATCCAGAGCAAAATGTGCCCAAACGCAAGCGTAGCTTCAAGGCTATTGTCACAGCCGCCACAATGTCCAGCAAGCTCAGCCAACTGGCCAGCGAGAGGCCAAATGGAGAGGTGAAAACGGAGCTCTGTGAGAGTGTGGACAACAGCAcaCCGCCCACAAAGACAACCTACGTCAGCTATACTAATCACGCCATATGAAGATGCATTCCTGAGAAGAAGATTCTAAAATGTTTACATGAGGCATGGATTAAAGGCACTGACTGGAACTAAAGCATGACACTATGATGTTGTTCGTGGTAAGAGGACGACTGTTTGGACTGAGACATGAGTCGTTTTTTCTAACATTTAAACTGTGTGGCCATGCAGCAGTCAGACAGAAGAGCACAAGTTGCTACTGGTGTAGCAGCAAAAGAGAAGTGTTATATCAGTGGaaacaaagaacaagagaaaataatatatatatattaaaaaaaaaaaactaagaaaacaaaggaaaactATTGGAGTCAACCATGTTAGTCGTTATTCTAATTGTAAGTATTTTGTGGTCGTGCAGATTTTTTAATTCTTGTTCCACAGTGTCAGATCTGCATTTGAAAAATGCATTCGTCTCTTGTATCGGCTACTCTGGTCAATTAGCCCTGGGTTGTAAGTGTGTATATGCCATGGTTGAAGCATGCCaatttttatacaaataatttatttataataaaggaATGTTTTTGAAATGTG

Function

symbol description
grm8b Predicted to enable group III metabotropic glutamate receptor activity. Predicted to be involved in G protein-coupled glutamate receptor signaling pathway and regulation of glutamatergic synaptic transmission. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane. Is expressed in brain and sensory system. Human ortholog(s) of this gene implicated in attention deficit hyperactivity disorder; autistic disorder; and schizophrenia. Orthologous to human GRM8 (glutamate metabotropic receptor 8).
grm8 Enables G protein-coupled receptor activity and glutamate receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled glutamate receptor signaling pathway. Predicted to be located in presynaptic membrane. Predicted to be active in GABA-ergic synapse and glutamatergic synapse. Predicted to be integral component of presynaptic active zone membrane. Implicated in attention deficit hyperactivity disorder; autistic disorder; and schizophrenia. Biomarker of multiple sclerosis.

NR:

description
PREDICTED: metabotropic glutamate receptor 8

GO: NA

KEGG:

id description
K04610 GRM8; metabotropic glutamate receptor 8

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022672241.1 True 3606 mRNA 0.51 12 18672401 18838757

Neighbor

gene id symbol gene type direction distance location
LOC103032349 znf800 coding upstream 3941 18653276 ~ 18668460 (+)
LOC103032021 NA coding upstream 28322 18637244 ~ 18644079 (+)
LOC103027288 NA coding upstream 37454 18632303 ~ 18634947 (+)
LOC103026996 lamb1,lamb1a,LOC107662456,LOC107595246 coding upstream 57280 18577789 ~ 18615121 (+)
LOC103026700 lamb4 coding upstream 97034 18535874 ~ 18575367 (+)
pot1 NA coding downstream 54470 18893227 ~ 18937127 (+)
gpr37 gpr37,gpr37a,LOC107753714,LOC107698235,LOC106584563 coding downstream 100338 18939095 ~ 18950348 (+)
LOC103034777 wasl,wasla,LOC108275301,LOC107598884,LOC107659464 coding downstream 218030 19056787 ~ 19081399 (+)
iqub iqub coding downstream 259759 19098516 ~ 19114949 (+)
slc13a1 slc13a1 coding downstream 280790 19119547 ~ 19133880 (+)
G74714 NA non-coding upstream 44373 18627649 ~ 18628028 (+)
G74672 NA non-coding upstream 45991 18625071 ~ 18626410 (+)
G74668 NA non-coding upstream 138271 18533808 ~ 18534130 (+)
G74654 NA non-coding upstream 209765 18461444 ~ 18462636 (+)
G74535 LOC108436883 non-coding upstream 296862 18371716 ~ 18375539 (+)
G74770 NA non-coding downstream 118881 18957638 ~ 18970866 (+)
G74810 NA non-coding downstream 153921 18992678 ~ 18994863 (+)
G74831 NA non-coding downstream 243555 19082312 ~ 19082521 (+)
G74833 NA non-coding downstream 247046 19085803 ~ 19086231 (+)
G74951 fnbp4,LOC107598873,LOC107681673 non-coding downstream 639241 19477998 ~ 19481987 (+)
LOC103029914 scamp5,scamp5a,LOC108436905,LOC103363822,LOC107395508,LOC107703195 other upstream 193056 18470704 ~ 18479345 (+)
G74649 NA other upstream 217204 18454851 ~ 18455197 (+)
G74169 NA other upstream 2384072 16286676 ~ 16288329 (+)
svip svip other upstream 3094868 15572302 ~ 15577533 (+)
rpgrip1l rpgrip1l other upstream 3751398 14891534 ~ 14921003 (+)
G74832 NA other downstream 244059 19082816 ~ 19085556 (+)
cadps2 NA other downstream 301392 19140149 ~ 19322775 (+)
tmem17 tmem17,znf774,LOC107678976,LOC107753710 other downstream 621201 19459958 ~ 19462187 (+)
LOC103044129 NA other downstream 688455 19527212 ~ 19537617 (+)
LOC103028745 NA other downstream 1364862 20203619 ~ 20207955 (+)

Expression


Co-expression Network