LOC111193007 (rac2,LOC108436672,LOC107561353,LOC105892187,LOC107551172,LOC108231305,LOC106601467)



Basic Information


Item Value
gene id LOC111193007
gene name rac2,LOC108436672,LOC107561353,LOC105892187,LOC107551172,LOC108231305,LOC106601467
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information


Item Value
chromosome id NC_035898.1
NCBI id CM008301.1
chromosome length 34292151
location 200963 ~ 273632 (+)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence


>XM_022671575.1
GAGGAGGAGTGAGTGGAGGGGGGGAAACACACTGACAACTTTTCTGAAACAGACTGGTTTCCTGTATTGCACCTTCTTCACTTTTTGCACACTCTGGTTCTGTTGAGGCGCGTTAAAAAGCTGAAAAGAACAGCTCGGGGGGGAAGATGCAGGCCATAAAGTGTGTCGTTGTGGGTGACGGAGCTGTGGGGAAAACATGTTTGCTGATCAGCTACACCACCAATGCCTTCCCTGGAGAATATATCCCCACAGTGTTCGATAACTACTCGGCCAACGTGATGGTGGACAGCAAGCCCGTCAACCTGGGGCTCTGGGATACAGCCGGACAGGAGGATTACGACAGGCTCCGGCCTCTGTCCTACCCACAGACggatgTGTTTCTCATCTGCTTCTCTCTGGTGAGCCCGGCATCGTTTGAGAACGTCAGAGCCAAGTGGTACCCAGAGGTCAGGCACCATTGCCCCTCCACACCTATCATCCTGGTTGGCACCAAGCTTGATCTGAGGGACGAGAAGGAGACCATCGAGAAGCTGAAAGAGAAGAAACTGGCTCCAATCACCTATCCACAGGGTTTGGCACTGGCCAAAGAGATAGATTCGGTGAAGTACCTAGAGTGTTCAGCTCTTACTCAGCGGGGTCTGAAGACAGTGTTTGACGAGGCCATCCGCGCCGTGCTCTGCCCACAGCCCACCAAAGTGAAGAAGAAGGGCTGCATTCTGCTGTGAAAAGAAACGGATTCTAATGATGGAGAAGAAGATTCCTCTAAAGCGGATGGAAATTCTCTTTAAATCCCAATAATGCTAAAATAATACTGTTTAAAGCTTTCTCACATTGCTGATGCATTTGTTTACTTTTACCCTatgatggtgtgtttttttattcaataaacaacAGCAGTCtatgttatataaatataaaataaaggtatttaaattgtagttttgtctAGCGAGCGATAGTGCGGGGGAGTTGTTGAAGGTTATCCAGTGGTGTGGTGTTGTAGATGCAGAATAAACACCATTTTTTTCCATCTCCCGTTGGTACAAAATGTGTAGGTGGAGTTCAGACTAGCCCATTCCGTCATGATGCCCAGGATAAGGCTGTTTCTGTTTATAGATTTCTgcaggataataataatgaaagccACCTGATGCACGGTACTGTGGGATGATGGTTGAGCACATATCGTATTGTAACTCAGGCTCTTTGGTGTGACAATAAACAACTTTCCAAACAAATA

Function


symbol description
rac2 Predicted to enable GTP binding activity; GTPase activity; and protein kinase binding activity. Acts upstream of or within several processes, including defense response to other organism; leukocyte chemotaxis; and regulation of neutrophil migration. Located in cytoplasm. Is expressed in neutrophil and thymus. Human ortholog(s) of this gene implicated in immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis; immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia; and immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia. Orthologous to human RAC2 (Rac family small GTPase 2).

NR:

description
PREDICTED: ras-related C3 botulinum toxin substrate 2

GO:

id name namespace
GO:0032878 regulation of establishment or maintenance of cell polarity biological_process
GO:0001780 neutrophil homeostasis biological_process
GO:0007264 small GTPase mediated signal transduction biological_process
GO:0009611 response to wounding biological_process
GO:0002446 neutrophil mediated immunity biological_process
GO:2000391 positive regulation of neutrophil extravasation biological_process
GO:0016020 membrane cellular_component
GO:0005737 cytoplasm cellular_component
GO:0005525 GTP binding molecular_function

KEGG:

id description
K07860 RAC2; Ras-related C3 botulinum toxin substrate 2

RNA


RNA id representative length rna type GC content exon number start site end site
XM_022671575.1 True 1240 mRNA 0.46 7 200963 273632

Neighbor


gene id symbol gene type direction distance location
LOC103029565 LOC103029565 coding upstream 48738 116081 ~ 152225 (+)
LOC103029038 NA coding upstream 90301 51288 ~ 110662 (+)
LOC103034757 LOC108436653 coding downstream 41216 314848 ~ 365716 (+)
LOC103047457 NA coding downstream 127338 400970 ~ 407136 (+)
LOC111193013 NA coding downstream 240648 514280 ~ 528000 (+)
trnal-uag NA coding downstream 259139 532771 ~ 532853 (+)
trnal-caa NA coding downstream 259498 533130 ~ 533212 (+)
G6876 NA non-coding upstream 1183 199397 ~ 199780 (+)
G6851 NA non-coding upstream 1999 188135 ~ 198964 (+)
G6852 NA non-coding upstream 4049 196620 ~ 196914 (+)
G6843 NA non-coding upstream 46563 138624 ~ 154400 (+)
G6895 NA non-coding downstream 106972 380604 ~ 380940 (+)
G6928 NA non-coding downstream 270802 544434 ~ 574624 (+)
G6929 NA non-coding downstream 270990 544622 ~ 576356 (+)
G6939 NA non-coding downstream 324929 598561 ~ 599050 (+)
LOC111194143 NA non-coding downstream 761440 1035072 ~ 1035957 (+)
G6901 LOC108436678 other downstream 139499 413131 ~ 437388 (+)
G6995 NA other downstream 427132 700764 ~ 702320 (+)
G7109 NA other downstream 1066574 1340206 ~ 1345431 (+)
LOC103037883 LOC105898698,LOC103360086,LOC101074561,LOC107391594,LOC102794576,LOC103154361,LOC100701095,LOC105938735,LOC105901802 other downstream 1765755 2039387 ~ 2047563 (+)
carm1 carm1 other downstream 1776651 2050283 ~ 2080541 (+)

Expression



Co-expression Network