CI01000009_10795119_10827802 (ERBB4B, ERBB4)


Basic Information

Item Value
gene id CI01000009_10795119_10827802
gene name ERBB4B, ERBB4
gene type coding
species grasscarp (Ctenopharyngodon idella)
category of species economic fish

Chromosome Information

Item Value
chromosome id CI01000009
NCBI id null
chromosome length 16003125
location 10795073 ~ 10827936 (-)
genome version v1_2015/06_NatureGenetics_grasscarp_Genome

Sequence

>CI01000009_10795119_10827802.mRNA
AGTGGTAGGACAGATGAGAGATGATAGGAAACTATGGGGAAGTTAGTTATTTACTGGCATGAATGCTCTTGTATTAATAATAAACATATCTTTTGCAGTTTTGGATCGTATGATATGTGACCCGCTGTGCTCTGATGCTGGCTGCTGGGGTCCGGGGCCCGACCAGTGCCTGTCCTGTCGGTTCTTTAGCAGGGGACGCACCTGTGTTGAATCCTGCAACCTGCACGAAGGGGATTTCACAAAGATTCATGTCTCCATCCTCTAGACAAACAATAACAAAACAGCAGTGCAGCACGTCCCCTGGCTTTGGAGAGCAGGTTGCAATGATGAAACTGAATCAGCACCAGGGCTCGTGCACCCTGCGATCGTCCCACATGATTCTTTTGCCTTGCAGACTGGCCAGCTCTAGGCCCAAGCTGCTCACCAGGCCTTATGTGGTCGAGAAGCGGGAGGCGGGTTTGGAGAGGGATGTACGTGAGTTCGCAAATGGTTCAGTGTGCTTGGAGTGTGACGCACAGTGTGAGGTGGCAGATGATGACGGTCTTACCTGCACTGGGCCTATGATTTTGATAAGACTTGAAGACGGACCCAACTGCGTGGAAAAATGCCCTGATGGCCTACAGGGAGCAAACAGCTTCATCTTCAAATATGCTGAGGCCAACAATGAGTGTCACCCCTGCCATGTCAACTGCACCCAGGGATGCACAGGGCCTCGTCTGCAAGACTGCATTGGCATGATGGACAGATACTTTGTTTATATAATACTATCACAGAATGGTTTCAATAGTCTCTCTTGCACATTTGGAAAAGACATGGCAGGTTACATAAAACAAGATGTCAGGTATCCTGTCCTCCTTCCCCTGCAATATACGGCAGTGGCACGGACTCCCCTCATTGCGGCTGGGGTTATTGGGGGATTGTTTGTGGTGATCATCGTGGGGCTGAGTGTTGCTATATCAGTCAGAAGGAAGAGCATCAAGAAGAAGAGAGCCTTGAGACGCTTCTTGGAGACTGAGTTGGTAGAGCCTCTGACGCCCAGCGGTGCAGCCCCAAACCAGGCCCAACTGCGCATTCTGAAAGAGACCGAGCTGAAACGGGTGAAGATTCTGGGAGCCGGGGCCTTCGGCACCGTCTACAAGGGCATCTGGGTTCCTGAGGGTGAGACTGTGAAGATTCCCGTTGCCATAAAGATCTTGAACGAGGCGACGGGCCCCAAAGCCAATGTAGAGTTCATGGATGAAGCTCTGATCATGGCCAGCATGGAGCATCCTCACTTGGTGCGTTTATTGGGTGTGTGTCTGAGCCCCACCATACAGCTGGTCACTCAGCTCATGCCCCATGGCTGTCTGCTGGACTACGTGCACGAACACAAAGACAACATCGGCTCCCAGTTACTGCTCAACTGGTGTGTTCAGATCGCCAAGGTTAATGGCAGTCTGAGGAGAAAAAATGCACTTCATGCAATAGATTATTGATGAAATAATCAGGCATGAAAGTAATTTTGATGAGTAGATTAATAAA

Function

symbol description
erbb4b Predicted to enable epidermal growth factor receptor binding activity and transmembrane receptor protein tyrosine kinase activity. Predicted to be involved in positive regulation of cell population proliferation; positive regulation of kinase activity; and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within protein phosphorylation. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be part of receptor complex. Predicted to be active in basal plasma membrane. Predicted to be integral component of plasma membrane. Is expressed in heart; muscle; nervous system; and trunk. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Orthologous to human ERBB4 (erb-b2 receptor tyrosine kinase 4).
erbb4 Enables several functions, including epidermal growth factor receptor binding activity; protein homodimerization activity; and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including positive regulation of phosphorylation; positive regulation of signal transduction; and protein phosphorylation. Located in basolateral plasma membrane; mitochondrion; and nucleus. Part of receptor complex. Implicated in amyotrophic lateral sclerosis type 19; colorectal cancer; esophagus squamous cell carcinoma; hepatocellular carcinoma; and lung adenocarcinoma. Biomarker of carcinoma (multiple); ductal carcinoma in situ; reproductive organ cancer (multiple); and urinary bladder cancer.

NR:

description
receptor tyrosine kinase, partial

GO:

id name namespace
GO:0006468 protein phosphorylation biological_process

KEGG: NA

RNA

RNA id representative length rna type GC content exon number start site end site
CI01000009_10795119_10827802.mRNA True 1521 mRNA 0.50 14 10795073 10827936

Neighbor

gene id symbol gene type direction distance location
CI01000009_10762456_10773627 NA coding downstream 20161 10761302 ~ 10774912 (-)
CI01000009_10631280_10637275 MYLZ3, MYL1 coding downstream 157798 10631086 ~ 10637275 (-)
CI01000009_10414678_10421940 NA coding downstream 373133 10413808 ~ 10421940 (-)
CI01000009_10355985_10360375 CYP27A7 coding downstream 434698 10355735 ~ 10360375 (-)
CI01000009_10330884_10337327 NA coding downstream 457746 10330780 ~ 10337327 (-)
CI01000009_10830928_10886836 ERBB4, ERBB4A coding upstream 2992 10830928 ~ 10886836 (-)
CI01000009_10925943_10927369 ERBB4 coding upstream 97946 10925882 ~ 10928279 (-)
CI01000009_11030714_11032123 NA coding upstream 202739 11030675 ~ 11035630 (-)
CI01000009_11071390_11075169 NA coding upstream 242742 11067012 ~ 11075433 (-)
CI01000009_11102518_11109578 NA coding upstream 274185 11102121 ~ 11109578 (-)
G57439 NA non-coding downstream 47292 10747514 ~ 10747781 (-)
G57436 NA non-coding downstream 56619 10738072 ~ 10738454 (-)
G57435 NA non-coding downstream 57748 10736863 ~ 10737325 (-)
G57426 NA non-coding downstream 72984 10721703 ~ 10722089 (-)
G57418 NA non-coding downstream 101398 10693345 ~ 10693675 (-)
G57456 NA non-coding upstream 323914 11151850 ~ 11256971 (-)
G57527 NA non-coding upstream 466700 11294636 ~ 11294872 (-)
G57533 NA non-coding upstream 487472 11315408 ~ 11315645 (-)
G57550 NA non-coding upstream 534343 11362279 ~ 11362547 (-)
CI01000009_08858198_08860555 NA other downstream 1934510 8856310 ~ 8860563 (-)
G55814 NA other downstream 2367061 8425821 ~ 8428012 (-)
G53515 NA other downstream 5289825 5502395 ~ 5505248 (-)
G52828 NA other downstream 6563604 4217420 ~ 4231469 (-)
CI01000009_03261739_03262843 NA other downstream 7533116 3261038 ~ 3262843 (-)
G59097 NA other upstream 1460281 12288217 ~ 12289518 (-)
CI01000009_13975122_13976026 NA other upstream 3147452 13975099 ~ 13978614 (-)
G59490 NA other upstream 3205628 14033564 ~ 14037873 (-)
G59811 NA other upstream 4034461 14862397 ~ 14887464 (-)
G59941 NA other upstream 4304168 15132104 ~ 15132503 (-)

Expression


Co-expression Network