btk (btk)


Basic Information

Item Value
gene id btk
gene name btk
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035920.1
NCBI id CM008323.1
chromosome length 47266144
location 13941252 ~ 13973029 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_007236470.3
GCACCAGTAACACACGGAAACCAGTGAGTGCCAGCTCAGAGACCGGGCATCAGACTGGGTTAACGGGTCAGAGTGGATCTGGGAGTCAGGGTAACGTCAAATCTGGATGAAAAATGTCAGATACTCTACTGGAGGAGGTTTTTATAAAGCGCTCCCagcaaaagaagaaaacatCACCCTTAAACTTTAAAGAAAGGTTATTCGTTCTCACACCGGACAAGATTTCATACTACGACTTTGATGTCGAAAAAGCAAAAAAGAAGGGGTTAAAGGGATATGTGGACACAGAAAAGATTAAAGGTGTAGAGACTGTGATGCCAGAAGACAGCGCTCCTCTAGAACGACTGTTTCCATTTCAGGTCATCTATGATGAGGGACCACTCTACGTATTCGCGCGAACAGATGATGTGCGAAAGCTGTGGATGAACAAAATAAGACATGTGATTCGCTTCAACAAAGATCTAATACAGAAATATCACCCCTGCTTCTGGGAGGACGGCGCGTGGAAGTGCTGTCAGCAGGAAGTGAAGCAGGCTATGGGCTGCAGAGTGATCAATACCAAAAATGGAGgaCTTTTCAAAAGTTCTCGGCGTCAATCCAGAAAACCGCTCCCGCCAACACCAGAAGAGGAAAAGCCCCCCAGACCCCTGCCCCCACAGCCACCGCCACAGCCTGGCTTCACGGTGGGGATGACGGTCATCGCCGAGTACGAGTACGCCCCTATGGCACCTCAGGACCTGGAGCTGAGGAAGGACGAGGAGTACACAGTGCTGCAGATATGCGACGCAAACTGGTTAAGAGCCAGAGATAAATATGGACAAGAGGGATACATTCCCAGCAACTATGTTGTCGAGGCCCTGAATGGACTGGAGAAGTGCGAatGGTATTGCAAGAACATGAACCGCAGTCAGGCTGAGAATTTACTGAAAACTGAGaataaaGATGGAGGTTTTCTGGTACGAGATTCTGGACGATTAGCTGGAAAATACACAGTGTCAGTTTTCACCAAGAGTGGAGGGGAAACTTCTGGCAGCTCTCGACACTACAACATATTAACCACTCAGCAAGGCCAGTTCTACCTGGCAGAGAAACATTATTTCAACAATATTCCAGATCTTATCAATTACCATCAGCACAACGCTGCAGGACTGGTGAGCAGGCTAAAATACATTGTGTCAAATCGAGCTCAACATGCTCCATCCACTGCTGGTCTGGGCTATGGTGTCTGGGAGATTGATCCTCGCCAGCTCACGTTTATAAAAGAGTTGGGTAACGGGCAGTTTGGGGTGGTGAAGTATGGAAAGTGGCAGGGTCGGCATGATGTAGCCATCAAAATGATCAAGGAGGGTTCTATGTCTGAGGATGATTTCATTGAAGAGGCTAAAGTCATGATGAAACTTCGACATGAAAACCTGGTTCAGCTTTATGGAGTTTGCACAAAACAAAGACCTATTTACATCGTCACTGAGTTTCTCCCTAACGGATGTTTGCTGACGTACCTGCGGGACTACCTGCAGCacccctctcctctcctgcttctGGAGATGTGTAAAGACGTCACAGAAGGCATGGCCTACCTAGAGTCCCAGCAGTATATCCACAGAGACCTTgcAGCAAGAAACTGCTTAGTAGACTCAAACGGCACAGTTAAAGTGACTGATTTTGGTTTGTCAAGatatgTTCTGGACGATGAGTACACCAGCTCTGTAGGCTCAAAGTTCCCTGTACGCTGGTCACCTCCAGAAGTTCTGCTTTACAGCAAGTTCAGCAGCAAGTCAGATATCTGGGCATTTGGTGTTTTAATGTGGGAAATCTACACACTGGGCCGAATGCCATATGACCGTATGAATAACACAGAGATAGTGGAAAAGGTCTCTGGTGGACATCGGCTGTATCGTCCTCAGTTGGCCAATGACAGAATCTACTCCGTAATGACCAGCTGTTGGCATGATAAAGCTGATGAGCGACCCACGTTCCAGGATCTCGTGATGATTATTCAAGACTTAGTGGAGAACATGGGCTAGAGAGCAGGCTGTGAAACATTGGGCATTAAGAAAAAATTGATCTTTTATTACAGAGTACAGATATTGTCCTAAGCTGGATGTTGGACTATGAATATTTAAAacgatttaaaaaatgaagatcGAATAGattctcatttttaaatgcCATTTGTTATAGTATGgattctttaaatgttttttttctactactactgttcCATCTCTTaaactgtactgtttttgtgcattaaaTTCTGCAAAGCTTCCAAAGTCAGATTACTGCAACTCTTTACTGTGCACAGTTGACTAAGAGGGGATCTCATCAGgattacattatttacagaTGAATTATCTTTGTGAATTTATTGTGTGTTGCTAAAACAGTATATCATTCATGTACGTGATGttattgaataaaatgaaagatATGTgga

Function

symbol description
btk Predicted to enable protein tyrosine kinase activity. Acts upstream of or within anterior/posterior pattern specification; negative regulation of Wnt signaling pathway; and regulation of canonical Wnt signaling pathway. Is expressed in hematopoietic system. Human ortholog(s) of this gene implicated in agammaglobulinemia (multiple); isolated growth hormone deficiency type III; and lymphoma (multiple). Orthologous to human BTK (Bruton tyrosine kinase).

NR:

description
tyrosine-protein kinase BTK isoform X1

GO:

id name namespace
GO:0018108 peptidyl-tyrosine phosphorylation biological_process
GO:0035556 intracellular signal transduction biological_process
GO:0005524 ATP binding molecular_function
GO:0004713 protein tyrosine kinase activity molecular_function

KEGG:

id description
K07370 BTK; Bruton agammaglobulinemia tyrosine kinase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_007236470.3 True 2437 mRNA 0.45 19 13941252 13973029

Neighbor

gene id symbol gene type direction distance location
timm8a timm8a,LOC107593201,LOC107680336,LOC107742474 coding downstream 10340 13928962 ~ 13930912 (-)
sil1 NA coding downstream 42539 13889589 ~ 13898713 (-)
csnk1a1 csnk1a1,LOC106611977,LOC107554841,LOC107742481,LOC106604944,LOC107593197 coding downstream 54166 13859221 ~ 13887086 (-)
hspa9 hspa9,LOC106604950,LOC106611979 coding downstream 142619 13780145 ~ 13798633 (-)
LOC111195730 NA coding downstream 163656 13774336 ~ 13777596 (-)
LOC111195849 NA coding upstream 2053688 16026717 ~ 16027163 (-)
LOC103026525 LOC108427881 coding upstream 2071149 16044178 ~ 16142579 (-)
trnae-uuc_23 NA coding upstream 2170259 16143288 ~ 16143359 (-)
cenpi cenpi coding upstream 2522327 16495356 ~ 16521829 (-)
tmem35a tmem35a,tmem35,LOC107724834,LOC107688707 coding upstream 2550057 16523086 ~ 16527085 (-)
G205387 NA non-coding downstream 107307 13833567 ~ 13833945 (-)
G205386 NA non-coding downstream 113865 13826512 ~ 13827387 (-)
G205378 NA non-coding downstream 161747 13768739 ~ 13779505 (-)
G205363 NA non-coding downstream 197905 13742620 ~ 13743347 (-)
G205361 hdac3,LOC103471067 non-coding downstream 253416 13685401 ~ 13687836 (-)
G205423 gsr,LOC107680979 non-coding upstream 12801 13985830 ~ 13991653 (-)
G205401 NA non-coding upstream 19724 13992753 ~ 13995460 (-)
G205448 NA non-coding upstream 257296 14230325 ~ 14230606 (-)
G205456 NA non-coding upstream 319017 14292046 ~ 14292683 (-)
G205459 NA non-coding upstream 336296 14309325 ~ 14309690 (-)
LOC103033675 LOC108410893 other downstream 22867 13902203 ~ 13918385 (-)
G205375 NA other downstream 163631 13744353 ~ 13777621 (-)
LOC111195729 NA other downstream 201331 13733713 ~ 13739921 (-)
G204671 NA other downstream 2357178 11583200 ~ 11584074 (-)
G204584 NA other downstream 3296565 10644254 ~ 10644687 (-)
LOC103035169 LOC108427892,LOC107740141,LOC107554835,LOC107593202,LOC108268827 other upstream 1648 13974677 ~ 13978450 (-)
pcdh19 pcdh19,LOC107680972,LOC107740148,LOC107688683 other upstream 1434915 15407944 ~ 15567635 (-)
G205640 NA other upstream 1570888 15543917 ~ 15545622 (-)
G205670 NA other upstream 1858621 15831650 ~ 15832094 (-)
drp2 drp2,LOC107724836,LOC107593231 other upstream 2230908 16203937 ~ 16365647 (-)

Expression


Co-expression Network