grhpr (grhpr,grhpra,LOC107550900,LOC107756505,LOC107730677,LOC105908753,LOC107680659)


Basic Information

Item Value
gene id grhpr
gene name grhpr,grhpra,LOC107550900,LOC107756505,LOC107730677,LOC105908753,LOC107680659
gene type coding
species mexican tetra (Astyanax mexicanus)
category of species ornamental fish

Chromosome Information

Item Value
chromosome id NC_035920.1
NCBI id CM008323.1
chromosome length 47266144
location 33800102 ~ 33812322 (-)
genome version Astyanax_mexicanus-2.0_2017_mexican_tetra_Genome

Sequence

>XM_022684009.1
GAGCCCCTGTTCCATGCTGCAGCAGTAGTGTAAACACAGCCGGCTACGCTAGTTAGCTGCTGTACTTAGCCCTGTGAGCTCCTGCAGGGCTTTAACCCAGCTGTATCTCTGCAGTTATCAATTTTTATCAGTTTTCTGATTCCAGAACCTCCTCCAGCTGCTGTGTTACCCGCAGTATGAGCGCTCAGACCCGGCTGAAGGTGTTCGTGACCCGGCGGCTCCCTCAGGAGGGCATGGAGCTCCTGCAGCAGTCAGCAGGGTGTACTGTATCAGTGTGGGACTCCGATGAACCGGTTCCTCGAGCAGAACTCCTTAAGGGGGTGGAAGGAGCTCACGGTCTGCTCTGCCTGCTCTCGGACCGGATCGACACCGAGGTTCTGGATGCAGCGGGCCCCAACCTGAAAGTTATCAGCACCCTGTCTGTGGGATTCGACCACCTCGCAATTGATGAGGTAAAGAAACGGGGGATCCGCGTTGGCTACACTCCAGATGTGCTGACAGATGCTACAGCTGAGTTGACTGTAGCTCTTTTATTGGCCACTGCTCGACGGCTACCTGAGGGAATACAGGAGGTGAAAAGTGGTGGCTGGAGCACCTGGAAGCCACTGTGGCTGTGTGGTTATGGGCTTTCTGGCAGTACTGTTGGAGTGATTGGCCTGGGACGcatagGCCTGGCCATTGCACGAAGGCTGATGCCGTTTGGGGTAAAGAGGCTGCTTTACTCAGGACGGCAGCCCAAACCACAGGCTCAGGAAGTGGACGGAGAATACGtACCATTGGACACACTCTTgagtgagagtgattttgtggtGGTGTCTTGTGCTCTGACCCCCGACACTCAGGGTCTGTGTAACAAGGCCTTCTTCAGCAAGATGAAGAAAACTGCAGTCTTCATCAACACCAGCAGAGGAGCTGTTGTGAATCAAGAGGACCTGTTTGAAGCCCTCTCTACTGGACAGATTGCTGCAGCCGGGCTTGATGTGACAACTCCAGAGCCACTGCCCACTGACCATCCCTTACTGACCCTCAACAACTGCGTGGTTCTTCCCCACATTGGCAGTGCCACCTATTCCACACGTGGAATTATGGCTCAGCTGTCTGCCAACAACCTGCTGGCCGGCCTGAGTGGAGATGCTATGGCCAGTGAACTGAAGATGTAGGGCCCCCTAAGTGGGTTCTGACATGAGCACAAACACTCCTCCAGCCTCCTGAGTAGAGACGAGGGATGACCCTGACCAGAGATGCTGTTGAGATTTAGATACCCTGTAGTACTCACTAATTATCAATCATCTCACTTACTGCTGCAatattactttttactgtagatgttttacattttctatGTCTGACAATTTCATAAAACAATCACTTATA
>XM_022684011.1
CTCCAGCACCACTCAGATCTTCCTTACCTGGCTGTTCTCCTACTGACCCTGAAACCAAACACCTGGCCTGCAGCACGTGCTGCACTCAGATTCACTCAGAACCTCCTCCAGCTGCTGTGTTACCCGCAGTATGAGCGCTCAGACCCGGCTGAAGGTGTTCGTGACCCGGCGGCTCCCTCAGGAGGGCATGGAGCTCCTGCAGCAGTCAGCAGGGTGTACTGTATCAGTGTGGGACTCCGATGAACCGGTTCCTCGAGCAGAACTCCTTAAGGGGGTGGAAGGAGCTCACGGTCTGCTCTGCCTGCTCTCGGACCGGATCGACACCGAGGTTCTGGATGCAGCGGGCCCCAACCTGAAAGTTATCAGCACCCTGTCTGTGGGATTCGACCACCTCGCAATTGATGAGGTAAAGAAACGGGGGATCCGCGTTGGCTACACTCCAGATGTGCTGACAGATGCTACAGCTGAGTTGACTGTAGCTCTTTTATTGGCCACTGCTCGACGGCTACCTGAGGGAATACAGGAGGTGAAAAGTGGTGGCTGGAGCACCTGGAAGCCACTGTGGCTGTGTGGTTATGGGCTTTCTGGCAGTACTGTTGGAGTGATTGGCCTGGGACGcatagGCCTGGCCATTGCACGAAGGCTGATGCCGTTTGGGGTAAAGAGGCTGCTTTACTCAGGACGGCAGCCCAAACCACAGGCTCAGGAAGTGGACGGAGAATACGtACCATTGGACACACTCTTgagtgagagtgattttgtggtGGTGTCTTGTGCTCTGACCCCCGACACTCAGGGTCTGTGTAACAAGGCCTTCTTCAGCAAGATGAAGAAAACTGCAGTCTTCATCAACACCAGCAGAGGAGCTGTTGTGAATCAAGAGGACCTGTTTGAAGCCCTCTCTACTGGACAGATTGCTGCAGCCGGGCTTGATGTGACAACTCCAGAGCCACTGCCCACTGACCATCCCTTACTGACCCTCAACAACTGCGTGGTTCTTCCCCACATTGGCAGTGCCACCTATTCCACACGTGGAATTATGGCTCAGCTGTCTGCCAACAACCTGCTGGCCGGCCTGAGTGGAGATGCTATGGCCAGTGAACTGAAGATGTAGGGCCCCCTAAGTGGGTTCTGACATGAGCACAAACACTCCTCCAGCCTCCTGAGTAGAGACGAGGGATGACCCTGACCAGAGATGCTGTTGAGATTTAGATACCCTGTAGTACTCACTAATTATCAATCATCTCACTTACTGCTGCAatattactttttactgtagatgttttacattttctatGTCTGACAATTTCATAAAACAATCACTTATA

Function

symbol description
grhpra Predicted to enable glycerate dehydrogenase activity; glyoxylate reductase (NADP+) activity; and hydroxypyruvate reductase activity. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in primary hyperoxaluria and primary hyperoxaluria type 2. Orthologous to human GRHPR (glyoxylate and hydroxypyruvate reductase).
grhpr Enables NADPH binding activity; oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; and protein homodimerization activity. Involved in excretion and glyoxylate metabolic process. Located in cytoplasm. Part of catalytic complex. Implicated in primary hyperoxaluria and primary hyperoxaluria type 2.

NR:

description
PREDICTED: glyoxylate reductase/hydroxypyruvate reductase

GO:

id name namespace
GO:0055114 oxidation-reduction process biological_process
GO:0008465 glycerate dehydrogenase activity molecular_function
GO:0051287 NAD binding molecular_function
GO:0030267 glyoxylate reductase (NADP) activity molecular_function
GO:0016618 hydroxypyruvate reductase activity molecular_function

KEGG:

id description
K00049 GRHPR; glyoxylate/hydroxypyruvate reductase

RNA

RNA id representative length rna type GC content exon number start site end site
XM_022684009.1 True 1374 mRNA 0.52 9 33800102 33810499
XM_022684011.1 False 1328 mRNA 0.53 10 33800102 33812322

Neighbor

gene id symbol gene type direction distance location
LOC111195776 NA coding downstream 1173526 32614920 ~ 32626576 (-)
LOC103043395 adh5,LOC103043395,LOC108425010,LOC107680974,LOC107730660,LOC107696300,LOC107586060,LOC107756510 coding downstream 1190194 32602209 ~ 32609908 (-)
LOC103043705 LOC107680975,LOC107730661,LOC107696296 coding downstream 1199091 32592697 ~ 32601011 (-)
LOC103044229 LOC103044229,LOC108430909 coding downstream 1683538 32076591 ~ 32116564 (-)
rapgef2 rapgef2 coding downstream 2417580 31290134 ~ 31382522 (-)
mrpl18 mrpl18 coding upstream 28665 33840987 ~ 33844951 (-)
LOC111195843 NA coding upstream 40747 33853069 ~ 33854406 (-)
pdgfc pdgfc coding upstream 96787 33909109 ~ 34001611 (-)
fam198b fam198b coding upstream 399243 34211565 ~ 34220540 (-)
tmem144 NA coding upstream 409557 34221879 ~ 34229881 (-)
G209571 NA non-coding downstream 897 33797302 ~ 33799205 (-)
G209579 NA non-coding downstream 18095 33781743 ~ 33782007 (-)
G209546 NA non-coding downstream 50586 33749177 ~ 33749516 (-)
G209452 NA non-coding downstream 846585 32953027 ~ 32953517 (-)
G209440 NA non-coding downstream 914050 32885690 ~ 32886052 (-)
G209576 NA non-coding upstream 18898 33831220 ~ 33834676 (-)
G209575 NA non-coding upstream 22976 33835298 ~ 33838826 (-)
LOC111195844 NA non-coding upstream 258792 34071114 ~ 34073594 (-)
G209623 gria2,gria2b non-coding upstream 312040 34124362 ~ 34127776 (-)
G209625 NA non-coding upstream 323890 34136212 ~ 34151668 (-)
G209529 LOC103042373,LOC108425009,LOC108268400,LOC107730658,LOC107756507,LOC107667842,LOC107550901 other downstream 195113 33602099 ~ 33604989 (-)
G209458 NA other downstream 844017 32955615 ~ 32956085 (-)
gar1 gar1,LOC106513240,LOC107756508,LOC107680945,LOC107586061 other downstream 1160173 32629294 ~ 32639929 (-)
G209303 NA other downstream 2282210 31517433 ~ 31517892 (-)
G209256 NA other downstream 2525700 31273868 ~ 31274402 (-)
G209640 NA other upstream 358445 34170767 ~ 34212849 (-)
G209660 NA other upstream 422596 34234918 ~ 34274593 (-)
egf NA other upstream 808139 34620461 ~ 34656484 (-)
LOC103045435 asb5a,LOC108425000,LOC107602595,LOC107740119,LOC107569834,LOC107723803 other upstream 897449 34709771 ~ 34759091 (-)
G210059 NA other upstream 2898098 36710420 ~ 36710743 (-)

Expression


Co-expression Network